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Search Results to Eric M Poeschla

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One or more keywords matched the following items that are connected to Poeschla, Eric

Item TypeName
Concept HIV Integrase
Concept Integrases
Concept HIV Integrase Inhibitors
Academic Article LEDGF/p75 proteins with alternative chromatin tethers are functional HIV-1 cofactors.
Academic Article An essential role for LEDGF/p75 in HIV integration.
Academic Article Identification of the LEDGF/p75 HIV-1 integrase-interaction domain and NLS reveals NLS-independent chromatin tethering.
Academic Article A role for LEDGF/p75 in targeting HIV DNA integration.
Academic Article A new class of multimerization selective inhibitors of HIV-1 integrase.
Academic Article Comparison of wild-type and class I integrase mutant-FIV vectors in retina demonstrates sustained expression of integrated transgenes in retinal pigment epithelium.
Academic Article LEDGF dominant interference proteins demonstrate prenuclear exposure of HIV-1 integrase and synergize with LEDGF depletion to destroy viral infectivity.
Academic Article LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes.
Academic Article Unintegrated lentivirus DNA persistence and accessibility to expression in nondividing cells: analysis with class I integrase mutants.
Academic Article Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase.
Academic Article Integrase, LEDGF/p75 and HIV replication.
Academic Article Identification and characterization of the chromatin-binding domains of the HIV-1 integrase interactor LEDGF/p75.
Academic Article TALEN knockout of the PSIP1 gene in human cells: analyses of HIV-1 replication and allosteric integrase inhibitor mechanism.
Academic Article Integrase inhibitor reversal dynamics indicate unintegrated HIV-1 dna initiate de novo integration.
Academic Article The mechanism of H171T resistance reveals the importance of Nd-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase.
Grant Dependency Factors in HIV-1 Cytoplasmic-Nuclear Transit and Intgeration
Grant Lentiviral Genome Processing
Grant Lentiviral Genome Processing
Academic Article Multivalent interactions essential for lentiviral integrase function.
Academic Article Allosteric Integrase Inhibitor Influences on HIV-1 Integration and Roles of LEDGF/p75 and HDGFL2 Host Factors.

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  • Integrases

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