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Search Results to James Veblen DeGregori

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DeGregori, James

One or more keywords matched the following items that are connected to DeGregori, James

Item Type	Name
Academic Article	A murine homolog of the yeast RNA1 gene is required for postimplantation development.
Academic Article	Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.
Academic Article	Fiber knob modifications overcome low, heterogeneous expression of the coxsackievirus-adenovirus receptor that limits adenovirus gene transfer and oncolysis for human rhabdomyosarcoma cells.
Academic Article	The genetics of the E2F family of transcription factors: shared functions and unique roles.
Academic Article	Defective gene expression, S phase progression, and maturation during hematopoiesis in E2F1/E2F2 mutant mice.
Academic Article	p53 mediates senescence-like arrest induced by chronic replicational stress.
Academic Article	Replicational stress selects for p53 mutation.
Academic Article	Declining cellular fitness with age promotes cancer initiation by selecting for adaptive oncogenic mutations.
Academic Article	Irradiation selects for p53-deficient hematopoietic progenitors.
Academic Article	Prolactin stimulates activation of c-jun N-terminal kinase (JNK).
Academic Article	Active RB elicits late G1/S inhibition.
Academic Article	Surprising dependency for retinoblastoma protein in ras-mediated tumorigenesis.
Academic Article	Mutation-specific control of BCR-ABL T315I positive leukemia with a recombinant yeast-based therapeutic vaccine in a murine model.
Academic Article	Irradiation alters selection for oncogenic mutations in hematopoietic progenitors.
Academic Article	Ionizing radiation and hematopoietic malignancies: altering the adaptive landscape.
Academic Article	Aging-associated changes in hematopoiesis and leukemogenesis: what's the connection?
Academic Article	Challenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?
Concept	Mutation
Concept	Germ-Line Mutation
Concept	Mutation, Missense
Academic Article	Cancer evolution is associated with pervasive positive selection on globally expressed genes.
Academic Article	Patterns of somatically acquired amplifications and deletions in apparently normal tissues of ovarian cancer patients.
Academic Article	Stochastic modeling indicates that aging and somatic evolution in the hematopoetic system are driven by non-cell-autonomous processes.
Academic Article	Toward an evolutionary model of cancer: Considering the mechanisms that govern the fate of somatic mutations.
Academic Article	Stochastic modeling reveals an evolutionary mechanism underlying elevated rates of childhood leukemia.
Academic Article	The landscape of somatic mutations in protein coding genes in apparently benign human tissues carries signatures of relaxed purifying selection.
Academic Article	Changing mutational and adaptive landscapes and the genesis of cancer.
Grant	Diet-Induced Adaptive Leukemogenesis: BCR-Abl dependent upregulation of folate re
Grant	Nrf2-mediated impaired hematopoietic stem cell fitness following irradiation
Grant	Poor competition in hematopoietic stem/progenitor pools favors tumorigenesis
Grant	Aging-associated alterations in adaptive landscapes and the evolution of leukemia
Academic Article	Connecting Cancer to Its Causes Requires Incorporation of Effects on Tissue Microenvironments.
Academic Article	Urea Cycle Sustains Cellular Energetics upon EGFR Inhibition in EGFR-Mutant NSCLC.
Academic Article	Decoy fitness peaks, tumor suppression, and aging.
Concept	Mutation Rate
Academic Article	A generalized theory of age-dependent carcinogenesis.
Grant	Understanding and circumventing aging-dependent changes in the bone marrow microenvironment that promote leukemogenesis
Academic Article	FERMI: A Novel Method for Sensitive Detection of Rare Mutations in Somatic Tissue.
Academic Article	Somatic maintenance impacts the evolution of mutation rate.
Academic Article	Cancer as a disease of old age: changing mutational and microenvironmental landscapes.
Academic Article	Shedding Light on Mutant Clonal Dynamics and Cancer Risk in the Skin.
Academic Article	Cells with Cancer-associated Mutations Overtake Our Tissues as We Age.
Academic Article	Clonal hematopoiesis: Mutation-specific adaptation to environmental change.
Academic Article	The sculpting of somatic mutational landscapes by evolutionary forces and their impacts on aging-related disease.
Academic Article	Dissecting stepwise mutational impairment of megakaryopoiesis in a model of Down syndrome-associated leukemia.
Academic Article	Dangerous Liaisons between Tet2 Mutation, Inflammatory Monocytes, and Leukemogenesis.
Academic Article	Therapeutic resistance in acute myeloid leukemia cells is mediated by a novel ATM/mTOR pathway regulating oxidative phosphorylation.

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