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Search Results to Michael R Narkewicz

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Narkewicz, Michael

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cystic fibrosis liver disease

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My research is focused on 2 major areas: 1. Cystic Fibrosis Liver Disease. I focus on clinical / translational research focused on identifying the underlying mechanisms of liver disease in CF, developing tests to identify liver disease in CF and to predict the subsequent development of advanced liver disease in CF using radiology, biochemistry and clinical predictors. 2. Studies of the impact of CFTR modulator and corrector therapies on GI and liver manifestations in CF 3. Clinical trials of antiviral therapy for chronic hepatitis B and C in children and adolescents.

One or more keywords matched the following items that are connected to Narkewicz, Michael

Item Type	Name
Academic Article	Outcome of syndromic paucity of interlobular bile ducts (Alagille syndrome) with onset of cholestasis in infancy.
Academic Article	Oxidant injury to hepatic mitochondria in patients with Wilson's disease and Bedlington terriers with copper toxicosis.
Academic Article	Serine and glycine metabolism in hepatocytes from mid gestation fetal lambs.
Academic Article	Effect of ursodeoxycholic acid therapy on hepatic function in children with intrahepatic cholestatic liver disease.
Academic Article	Correction of hypozincemia following liver transplantation in children is associated with reduced urinary zinc loss.
Academic Article	Development of primary culture of ovine fetal hepatocytes for studies of amino acid metabolism and insulinlike growth factors.
Academic Article	Fulminant hepatitis associated with centrilobular hepatic necrosis in young children.
Academic Article	Cysteine supplementation and reduction of total parenteral nutrition-induced hepatic lipid accumulation in the weanling rat.
Academic Article	Long-term results with the Kasai operation for biliary atresia.
Academic Article	Biliary atresia: an update on our understanding of the disorder.
Academic Article	Four cases of severe hepatotoxicity associated with pemoline: possible autoimmune pathogenesis.
Academic Article	Development of the liver and bile ducts.
Academic Article	Liver involvement in Alpers disease.
Academic Article	Hormonal control of specific gene expression in the rat liver during the suckling-weaning transition.
Academic Article	Portopulmonary hypertension in pediatric patients.
Academic Article	Abnormal concentrations of esterified carnitine in bile: a feature of pediatric acute liver failure with poor prognosis.
Academic Article	Characterization of acute liver failure and development of a continuous risk of death staging system in children.
Academic Article	Comparison of indices of vitamin A status in children with chronic liver disease.
Academic Article	Connective tissue growth factor expression is increased in biliary epithelial cells in biliary atresia.
Academic Article	Hormonal regulation of liver phosphoenolpyruvate carboxykinase and glucokinase gene expression at weaning in the rat.
Academic Article	Acute hepatitis and liver failure associated with influenza A infection in children.
Academic Article	The "C" of viral hepatitis in children.
Academic Article	Insulin and tri-iodothyronine induce glucokinase mRNA in primary cultures of neonatal rat hepatocytes.
Academic Article	Hepatic veno-occlusive disease and human herpes virus 7 infection in primary agammaglobulinemia.
Academic Article	Pulmonary vascular complications in asymptomatic children with portal hypertension.
Academic Article	Serine and glycine transport in fetal ovine hepatocytes.
Academic Article	Characterization and outcomes of young infants with acute liver failure.
Academic Article	Ontogeny of hepatic enzymes involved in serine- and folate-dependent one-carbon metabolism in rabbits.
Academic Article	Heavy breathing: a step to noninvasive assessment of hepatic fibrosis and function in infants and children.
Academic Article	Immunophenotype predicts outcome in pediatric acute liver failure.
Academic Article	Incidence and clinical significance of elevated liver function tests in cystic fibrosis clinical trials.
Academic Article	Decreasing incidence of symptomatic Epstein-Barr virus disease and posttransplant lymphoproliferative disorder in pediatric liver transplant recipients: report of the studies of pediatric liver transplantation experience.
Academic Article	Hepatic dysfunction following the Fontan procedure.
Academic Article	Plasma markers of platelet activation in cystic fibrosis liver and lung disease.
Academic Article	Biliary diversion for progressive familial intrahepatic cholestasis: improved liver morphology and bile acid profile.
Academic Article	Induction of cytosolic phosphoenolpyruvate carboxykinase in the ovine fetal liver by chronic fetal hypoglycemia and hypoinsulinemia.
Academic Article	Pathways of serine and glycine metabolism in primary culture of ovine fetal hepatocytes.
Academic Article	Interferon treatment for chronic hepatitis B: enhanced response in children 5 years old or younger.
Academic Article	Fulminant Epstein-Barr viral hepatitis: orthotopic liver transplantation and review of the literature.
Academic Article	Ontogeny of serine hydroxymethyltransferase isoenzymes in fetal sheep liver, kidney, and placenta.
Academic Article	Acute liver failure in children: the first 348 patients in the pediatric acute liver failure study group.
Academic Article	Improvement of cyclosporin absorption in children after liver transplantation by means of water-soluble vitamin E.
Academic Article	Niemann-pick disease type C in neonatal cholestasis at a North American Center.
Academic Article	Autoantibodies in mothers of children with neonatal liver disease.
Academic Article	Evaluation of a scoring system for assessing prognosis in pediatric acute liver failure.
Academic Article	Effect of vitamin E on transport processes in isolated rat hepatocytes.
Academic Article	Pattern of diagnostic evaluation for the causes of pediatric acute liver failure: an opportunity for quality improvement.
Academic Article	Risk factors for rejection and infection in pediatric liver transplantation.
Academic Article	Pathology of chronic hepatitis C in children: liver biopsy findings in the Peds-C Trial.
Academic Article	Epstein-Barr virus-related optic neuritis as a precursor to the development of posttransplant lymphoproliferative disease.
Academic Article	Choledochoduodenostomy in pediatric liver transplantation.
Academic Article	Pegylated interferon for chronic hepatitis C in children affects growth and body composition: results from the pediatric study of hepatitis C (PEDS-C) trial.
Academic Article	Intravenous N-acetylcysteine in pediatric patients with nonacetaminophen acute liver failure: a placebo-controlled clinical trial.
Academic Article	Pulmonary function in individuals who underwent liver transplantation: from the US cystic fibrosis foundation registry.
Academic Article	Evaluation of the liver injury unit scoring system to predict survival in a multinational study of pediatric acute liver failure.
Concept	Liver Diseases
Concept	Liver Cirrhosis
Concept	Liver
Concept	Liver Cirrhosis, Biliary
Concept	Liver Transplantation
Concept	Liver Function Tests
Concept	Chemical and Drug Induced Liver Injury
Concept	Liver Failure
Concept	Fatty Liver
Concept	Liver Failure, Acute
Concept	Mitochondria, Liver
Concept	Microsomes, Liver
Academic Article	Evaluating progression of liver disease from repeat liver biopsies in children with chronic hepatitis C: a retrospective study.
Academic Article	Cirrhosis and other liver disease in cystic fibrosis.
Academic Article	Intestinal lesions are associated with altered intestinal microbiome and are more frequent in children and young adults with cystic fibrosis and cirrhosis.
Academic Article	Baseline Ultrasound and Clinical Correlates in Children with Cystic Fibrosis.
Academic Article	Total Serum Bilirubin within 3 Months of Hepatoportoenterostomy Predicts Short-Term Outcomes in Biliary Atresia.
Academic Article	Cystic Fibrosis Liver Disease and Ursodeoxycholic Acid: One Small Step Forward, Miles to Go.
Academic Article	Lactate and Lactate: Pyruvate Ratio in the Diagnosis and Outcomes of Pediatric Acute Liver Failure.
Academic Article	Prevalence and Significance of Autoantibodies in Children With Acute Liver Failure.
Academic Article	Prevalence of elevated liver enzymes in children with cystic fibrosis diagnosed by newborn screen.
Academic Article	Cystic Fibrosis-related Liver Disease: Research Challenges and Future Perspectives.
Academic Article	Variceal Hemorrhage and Adverse Liver Outcomes in Patients With Cystic Fibrosis Cirrhosis.
Academic Article	Cystic Fibrosis-related cirrhosis.
Academic Article	Acoustic radiation force impulse of the liver after Fontan operation: Correlation with cardiopulmonary exercise test.
Academic Article	A Learning Collaborative Approach Increases Specificity of Diagnosis of Acute Liver Failure in Pediatric Patients.
Academic Article	A Multidisciplinary Approach to Pretransplant and Posttransplant Management of Cystic Fibrosis-Associated Liver Disease.
Academic Article	Liver Ultrasound Patterns in Children With Cystic Fibrosis Correlate With Noninvasive Tests of Liver Disease.
Academic Article	Integrating Clinical Ultrasound Into Screening for Cystic Fibrosis Liver Disease: Approach With Caution and Optimism.
Grant	Cystic Fibrosis Liver Disease Consortium
Academic Article	Heterogeneous Liver on Research Ultrasound Identifies Children with Cystic Fibrosis at High Risk of Advanced Liver Disease: Interim Results of a Prospective Observational Case-Controlled Study.
Academic Article	The Emergence of Elastography for Cystic Fibrosis Liver Disease.
Academic Article	Association Between Transient Elastography and Controlled Attenuated Parameter and Liver Ultrasound in Children With Cystic Fibrosis.
Academic Article	Health-related Quality of Life in a Prospective Study of Ultrasound to Detect Cystic Fibrosis-related Liver Disease in Children.
Academic Article	Long-term follow-up and liver outcomes in children with cystic fibrosis and nodular liver on ultrasound in a multi-center study.
Academic Article	Serum biomarkers correlated with liver stiffness assessed in a multicenter study of pediatric cholestatic liver disease.
Academic Article	Heterogeneous liver on research ultrasound identifies children with cystic fibrosis at high risk of advanced liver disease.
Academic Article	Prospective study of quantitative liver MRI in cystic fibrosis: feasibility and comparison to PUSH cohort ultrasound.
Academic Article	Cystic fibrosis liver disease in the post-modulator era.

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