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Search Results to Jonathan Mark Petrash

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Item TypeName
Academic Article Purification and properties of human liver aldehyde reductases.
Academic Article Prevention of diabetic vascular dysfunction by guanidines. Inhibition of nitric oxide synthase versus advanced glycation end-product formation.
Academic Article Kinetic characteristics of ZENECA ZD5522, a potent inhibitor of human and bovine lens aldose reductase.
Academic Article Aldose reductase catalysis and crystallography. Insights from recent advances in enzyme structure and function.
Academic Article Interrelationships among human aldo-keto reductases: immunochemical, kinetic and structural properties.
Academic Article Probing the active site of human aldose reductase. Site-directed mutagenesis of Asp-43, Tyr-48, Lys-77, and His-110.
Academic Article Kinetic alteration of human aldose reductase by mutagenesis of cysteine residues.
Academic Article Cloning, expression, and chaperone-like activity of human alphaA-crystallin.
Academic Article Specifically targeted modification of human aldose reductase by physiological disulfides.
Academic Article Modification of aldose reductase by S-nitrosoglutathione.
Academic Article 1.7 A structure of FR-1, a fibroblast growth factor-induced member of the aldo-keto reductase family, complexed with coenzyme and inhibitor.
Academic Article Structure-function studies of FR-1. A growth factor-inducible aldo-keto reductase.
Academic Article Involvement of cysteine residues in catalysis and inhibition of human aldose reductase. Site-directed mutagenesis of Cys-80, -298, and -303.
Academic Article Kinetic and structural characterization of the glutathione-binding site of aldose reductase.
Academic Article Characterization of the glutathione binding site of aldose reductase.
Academic Article A potential role for aldose reductase in steroid metabolism.
Academic Article Mechanism of inhibition of aldose reductase by menadione (vitamin K3).
Academic Article Aldo-keto reductases as modulators of stress response.
Academic Article Kinetic studies of FR-1, a growth factor-inducible aldo-keto reductase.
Academic Article Oxidative modification of aldose reductase induced by copper ion. Factors and conditions affecting the process.
Academic Article Effects of osmotic stress and hyperglycemia on aldose reductase gene expression in human renal proximal tubule cells.
Academic Article Structural and kinetic determinants of aldehyde reduction by aldose reductase.
Academic Article All in the family: aldose reductase and closely related aldo-keto reductases.
Academic Article Resolving isoforms of aldose reductase by preparative isoelectric focusing in the Rotofor.
Academic Article Functional studies of aldo-keto reductases in Saccharomyces cerevisiae.
Academic Article Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes.
Academic Article Erythrocyte aldose reductase activity and sorbitol levels in diabetic retinopathy.
Academic Article Dietary sources of aldose reductase inhibitors: prospects for alleviating diabetic complications.
Academic Article Regulation of aldose reductase by aldehydes and nitric oxide.
Academic Article Aldose reductase protects against early atherosclerotic lesion formation in apolipoprotein E-null mice.
Academic Article Inhibition of aldose reductase by dietary antioxidant curcumin: mechanism of inhibition, specificity and significance.
Academic Article Isolation and characterization of cDNA clones encoding aldose reductase.
Academic Article Aldose reductase-mediated induction of epithelium-to-mesenchymal transition (EMT) in lens.
Academic Article Functional genomic studies of aldo-keto reductases.
Academic Article Binding of 1-benzopyran-4-one derivatives to aldose reductase: a free energy perturbation study.
Academic Article Alteration of substrate selectivity through mutation of two arginine residues in the binding site of amadoriase II from Aspergillus sp.
Academic Article The isolation and characterization of ?-glucogallin as a novel aldose reductase inhibitor from Emblica officinalis.
Academic Article Inhibition of aldose reductase by Gentiana lutea extracts.
Academic Article Beta-glucogallin reduces the expression of lipopolysaccharide-induced inflammatory markers by inhibition of aldose reductase in murine macrophages and ocular tissues.
Academic Article Deletion of aldose reductase from mice inhibits diabetes-induced retinal capillary degeneration and superoxide generation.
Academic Article Formation of sorbitol 6-phosphate by bovine and human lens aldose reductase, sorbitol dehydrogenase and sorbitol kinase.
Academic Article Susceptibility of aldehyde and aldose reductases of human tissues to aldose reductase inhibitors.
Academic Article Refined 1.8 A structure of human aldose reductase complexed with the potent inhibitor zopolrestat.
Academic Article Kinetic and spectroscopic evidence for active site inhibition of human aldose reductase.
Academic Article Structural studies of aldo-keto reductase inhibition.
Academic Article The crystal structure of the aldose reductase.NADPH binary complex.
Academic Article Active site modification of aldose reductase by nitric oxide donors.
Academic Article Inhibition of aldose reductase by tannoid principles of Emblica officinalis: implications for the prevention of sugar cataract.
Academic Article Purification, crystallization and preliminary crystallographic analysis of porcine aldose reductase.
Academic Article Structure of a glutathione conjugate bound to the active site of aldose reductase.
Academic Article Mechanisms involved in the protection of UV-induced protein inactivation by the corneal crystallin ALDH3A1.
Academic Article Disruption of aldo-keto reductase genes leads to elevated markers of oxidative stress and inositol auxotrophy in Saccharomyces cerevisiae.
Academic Article Aldo-keto reductases in the eye.
Academic Article Aldose reductase deficiency in mice prevents azoxymethane-induced colonic preneoplastic aberrant crypt foci formation.
Academic Article Human and rodent aldo-keto reductases from the AKR1B subfamily and their specificity with retinaldehyde.
Academic Article Functional expression of novel human and murine AKR1B genes.
Academic Article Synthesis and biological evaluation of new piplartine analogues as potent aldose reductase inhibitors (ARIs).
Academic Article Exclusion of aldose reductase as a mediator of ERG deficits in a mouse model of diabetic eye disease.
Concept Amine Oxidase (Copper-Containing)
Concept L-Iditol 2-Dehydrogenase
Concept Aldehyde Reductase
Concept Sugar Alcohol Dehydrogenases
Concept Amino Acid Oxidoreductases
Concept Glucosephosphate Dehydrogenase
Concept 20-Hydroxysteroid Dehydrogenases
Concept Aldehyde Dehydrogenase
Concept Alcohol Oxidoreductases
Concept Oxidoreductases Acting on Aldehyde or Oxo Group Donors
Concept Hydroxyprostaglandin Dehydrogenases
Concept 20-alpha-Hydroxysteroid Dehydrogenase
Academic Article Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome.
Academic Article Alpha-crystallin-mediated protection of lens cells against heat and oxidative stress-induced cell death.
Academic Article Lack of association between VAP-1/SSAO activity and corneal neovascularization in a rabbit model.
Academic Article Design of an amide N-glycoside derivative of ?-glucogallin: a stable, potent, and specific inhibitor of aldose reductase.
Academic Article Aldose reductase inhibition prevents endotoxin-induced inflammatory responses in retinal microglia.
Academic Article Diabetes-induced impairment in visual function in mice: contributions of p38 MAPK, rage, leukocytes, and aldose reductase.
Academic Article Aldose reductase expression as a risk factor for cataract.
Academic Article Aldose reductase inhibition alleviates hyperglycemic effects on human retinal pigment epithelial cells.
Academic Article Aldose Reductase Mediates Transforming Growth Factor ?2 (TGF-?2)-Induced Migration and Epithelial-To-Mesenchymal Transition of Lens-Derived Epithelial Cells.
Academic Article Aldose reductase mediates retinal microglia activation.
Academic Article Characterization of Emodin as a Therapeutic Agent for Diabetic Cataract.
Academic Article Influence of aldose reductase on epithelial-to-mesenchymal transition signaling in lens epithelial cells.
Grant MOLECULAR STUDIES OF ALDOSE REDUCTASE AND CATARACT
Grant Aldose Reductase and Diabetic Eye Disease
Grant Novel Therapeutics Against Diabetic Eye Disease
Grant MOLECULAR BIOLOGY OF ALDOSE REDUCTASE AND CATARACT
Grant Molecular Signaling in Cataracts
Academic Article Inhibition of a-glucosidase, a-amylase, and aldose reductase by potato polyphenolic compounds.
Academic Article Aldose Reductase Inhibition Prevents Development of Posterior Capsular Opacification in an In Vivo Model of Cataract Surgery.
Academic Article Aldo-Keto Reductases: Multifunctional Proteins as Therapeutic Targets in Diabetes and Inflammatory Disease.
Academic Article Role of aldose reductase in diabetes-induced retinal microglia activation.
Concept Aldo-Keto Reductases
Academic Article Aldose reductase inhibition enhances lens regeneration in mice.
Academic Article Diabetes-Independent Retinal Phenotypes in an Aldose Reductase Transgenic Mouse Model.
Academic Article Mitigation of lens opacification by a functional food in a diabetic rodent model.

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