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Search Results to Kenneth Norman MacLean

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One or more keywords matched the following items that are connected to MacLean, Kenneth

Item TypeName
Academic Article Plasma albumin cysteinylation is regulated by cystathionine beta-synthase.
Academic Article Betaine supplementation improves the atherogenic risk factor profile in a transgenic mouse model of hyperhomocysteinemia.
Academic Article Hyperhomocysteinemia is associated with hypertriglyceridemia in mice with methylenetetrahydrofolate reductase deficiency.
Academic Article Cystathionine beta-synthase null homocystinuric mice fail to exhibit altered hemostasis or lowering of plasma homocysteine in response to betaine treatment.
Academic Article Integrated stress response modulates cellular redox state via induction of cystathionine ?-lyase: cross-talk between integrated stress response and thiol metabolism.
Academic Article Long-term betaine therapy in a murine model of cystathionine beta-synthase deficient homocystinuria: decreased efficacy over time reveals a significant threshold effect between elevated homocysteine and thrombotic risk.
Academic Article High homocysteine and thrombosis without connective tissue disorders are associated with a novel class of cystathionine beta-synthase (CBS) mutations.
Academic Article Altered expression of apoA-I, apoA-IV and PON-1 activity in CBS deficient homocystinuria in the presence and absence of treatment: possible implications for cardiovascular outcomes.
Concept Betaine-Homocysteine S-Methyltransferase
Concept Homocysteine
Academic Article Taurine alleviates repression of betaine-homocysteine S-methyltransferase and significantly improves the efficacy of long-term betaine treatment in a mouse model of cystathionine ?-synthase-deficient homocystinuria.
Academic Article Biomarkers of oxidative stress, inflammation, and vascular dysfunction in inherited cystathionine ?-synthase deficient homocystinuria and the impact of taurine treatment in a phase 1/2 human clinical trial.
Academic Article Derangement of hepatic polyamine, folate, and methionine cycle metabolism in cystathionine beta-synthase-deficient homocystinuria in the presence and absence of treatment: Possible implications for pathogenesis.

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  • Homocysteine

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