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Search Results to David Karasik

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Karasik, David

One or more keywords matched the following items that are connected to Karasik, David

Item Type	Name
Concept	Bone Density
Academic Article	Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
Academic Article	Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus.
Academic Article	Impact of the environment on the skeleton: is it modulated by genetic factors?
Academic Article	Mouse BMD quantitative trait loci show improved concordance with human genome-wide association loci when recalculated on a new, common mouse genetic map.
Academic Article	An atlas of genetic influences on osteoporosis in humans and mice.
Academic Article	Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.
Academic Article	Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.
Academic Article	Genetic variation in TRPS1 may regulate hip geometry as well as bone mineral density.
Academic Article	Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.
Academic Article	Bone mineral density loci specific to the skull portray potential pleiotropic effects on craniosynostosis.
Academic Article	Bone geometry and skeletal fragility.
Academic Article	Impact of common variation in bone-related genes on type 2 diabetes and related traits.
Academic Article	Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women.
Academic Article	Refined QTLs of osteoporosis-related traits by linkage analysis with genome-wide SNPs: Framingham SHARe.
Academic Article	Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies.
Academic Article	Meta-analysis of genome-wide scans provides evidence for sex- and site-specific regulation of bone mass.
Academic Article	Heritability of prevalent vertebral fracture and volumetric bone mineral density and geometry at the lumbar spine in three generations of the Framingham study.
Academic Article	Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study.
Academic Article	Deletion of SREBF1, a Functional Bone-Muscle Pleiotropic Gene, Alters Bone Density and Lipid Signaling in Zebrafish.
Academic Article	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.
Academic Article	Lrp5 Mutant and Crispant Zebrafish Faithfully Model Human Osteoporosis, Establishing the Zebrafish as a Platform for CRISPR-Based Functional Screening of Osteoporosis Candidate Genes.
Academic Article	Genetic variants modify the associations of concentrations of methylmalonic acid, vitamin B-12, vitamin B-6, and folate with bone mineral density.
Academic Article	An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits.
Academic Article	A Meta-Analysis of the Transferability of Bone Mineral Density Genetic Loci Associations From European to African Ancestry Populations.
Academic Article	Identification of Novel Loci Associated With Hip Shape: A Meta-Analysis of Genomewide Association Studies.
Academic Article	The genetics of bone mass and susceptibility to bone diseases.
Academic Article	Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis.
Academic Article	A genome-wide scan for pleiotropy between bone mineral density and nonbone phenotypes.
Academic Article	Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture.
Academic Article	Hip structural geometry in old and old-old age: similarities and differences between men and women.
Academic Article	Assessment of gene-by-sex interaction effect on bone mineral density.
Academic Article	Bone Strength Estimated by Micro-Finite Element Analysis (?FEA) Is Heritable and Shares Genetic Predisposition With Areal BMD: The Framingham Study.
Academic Article	A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density.
Academic Article	Genetic variation at the low-density lipoprotein receptor-related protein 5 (LRP5) locus modulates Wnt signaling and the relationship of physical activity with bone mineral density in men.
Academic Article	The influence of adult hip shape genetic variants on adolescent hip shape: Findings from a population-based DXA study.
Academic Article	Heritability and Genetic Correlations for Bone Microarchitecture: The Framingham Study Families.
Academic Article	Both indirect maternal and direct fetal genetic effects reflect the observational relationship between higher birth weight and lower adult bone mass.
Academic Article	Hip geometry variation is associated with bone mineralization pathway gene variants: The Framingham Study.
Academic Article	Genome-wide association with bone mass and geometry in the Framingham Heart Study.
Academic Article	Novel model of restricted mobility induced osteopenia in zebrafish.
Academic Article	Interactions of interleukin-6 promoter polymorphisms with dietary and lifestyle factors and their association with bone mass in men and women from the Framingham Osteoporosis Study.
Academic Article	Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study.
Academic Article	Association of a common polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene with bone phenotypes depends on plasma folate status.
Academic Article	Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium.
Academic Article	Opportunities and Challenges in Functional Genomics Research in Osteoporosis: Report From a Workshop Held by the Causes Working Group of the Osteoporosis and Bone Research Academy of the Royal Osteoporosis Society on October 5th 2020.
Academic Article	Increased plasma osteoprotegerin concentrations are associated with indices of bone strength of the hip.
Academic Article	Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus.
Academic Article	A Polymorphism in a gene encoding Perilipin 4 is associated with height but not with bone measures in individuals from the Framingham Osteoporosis Study.
Academic Article	Complex segregation analysis of the radiographic phalanges bone mineral density and their age-related changes.
Academic Article	Estrogen receptor beta polymorphisms are associated with bone mass in women and men: the Framingham Study.

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Bone Density