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Search Results to Thomas R Cech

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One or more keywords matched the following items that are connected to Cech, Thomas

Item TypeName
Academic Article Catalysis of RNA cleavage by a ribozyme derived from the group I intron of Anabaena pre-tRNA(Leu).
Academic Article Representation of the secondary and tertiary structure of group I introns.
Academic Article Relative orientation of RNA helices in a group 1 ribozyme determined by helix extension electron microscopy.
Academic Article Telomerase RNA localized in the replication band and spherical subnuclear organelles in hypotrichous ciliates.
Academic Article Movement of the guide sequence during RNA catalysis by a group I ribozyme.
Academic Article Telomerase RNAs of different ciliates have a common secondary structure and a permuted template.
Academic Article Two major tertiary folding transitions of the Tetrahymena catalytic RNA.
Academic Article Coaxially stacked RNA helices in the catalytic center of the Tetrahymena ribozyme.
Academic Article Kinetic pathway for folding of the Tetrahymena ribozyme revealed by three UV-inducible crosslinks.
Academic Article Joining the two domains of a group I ribozyme to form the catalytic core.
Academic Article Crystal structure of a group I ribozyme domain: principles of RNA packing.
Academic Article RNA tertiary structure mediation by adenosine platforms.
Academic Article Self-assembly of a group I intron active site from its component tertiary structural domains.
Academic Article Identification of ribozymes within a ribozyme library that efficiently cleave a long substrate RNA.
Academic Article Thermodynamic stability of the P4-P6 domain RNA tertiary structure measured by temperature gradient gel electrophoresis.
Academic Article A tertiary interaction in the Tetrahymena intron contributes to selection of the 5' splice site.
Academic Article Replacement of the conserved G.U with a G-C pair at the cleavage site of the Tetrahymena ribozyme decreases binding, reactivity, and fidelity.
Academic Article Energetics and cooperativity of tertiary hydrogen bonds in RNA structure.
Academic Article Self-splicing of the Tetrahymena intron from mRNA in mammalian cells.
Academic Article RNA tertiary folding monitored by fluorescence of covalently attached pyrene.
Academic Article Quantifying the energetic interplay of RNA tertiary and secondary structure interactions.
Academic Article Multiple folding pathways for the P4-P6 RNA domain.
Academic Article A hammerhead ribozyme allows synthesis of a new form of the Tetrahymena ribozyme homogeneous in length with a 3' end blocked for transesterification.
Academic Article Kinetic and secondary structure analysis of Naegleria andersoni GIR1, a group I ribozyme whose putative biological function is site-specific hydrolysis.
Academic Article Telomerase and the chromosome end replication problem.
Academic Article The Euplotes La motif protein p43 has properties of a telomerase-specific subunit.
Academic Article Tetrahymena telomerase is active as a monomer.
Academic Article Local RNA structural changes induced by crystallization are revealed by SHAPE.
Academic Article The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis.
Academic Article In vivo selection of better self-splicing introns in Escherichia coli: the role of the P1 extension helix of the Tetrahymena intron.
Academic Article Analysis of the structure of Tetrahymena nuclear RNAs in vivo: telomerase RNA, the self-splicing rRNA intron, and U2 snRNA.
Academic Article Ribozyme-mediated repair of defective mRNA by targeted, trans-splicing.
Academic Article X-ray crystallography of large RNAs: heavy-atom derivatives by RNA engineering.
Academic Article Reverse transcriptase motifs in the catalytic subunit of telomerase.
Academic Article Euplotes telomerase contains an La motif protein produced by apparent translational frameshifting.
Academic Article An early transition state for folding of the P4-P6 RNA domain.
Academic Article Effects of nucleotide analogues on Euplotes aediculatus telomerase processivity: evidence for product-assisted translocation.
Academic Article The Euplotes telomerase subunit p43 stimulates enzymatic activity and processivity in vitro.
Academic Article Structure of the Tetrahymena ribozyme: base triple sandwich and metal ion at the active site.
Academic Article Comparison of crystal structure interactions and thermodynamics for stabilizing mutations in the Tetrahymena ribozyme.
Academic Article Tetrahymena telomerase protein p65 induces conformational changes throughout telomerase RNA (TER) and rescues telomerase reverse transcriptase and TER assembly mutants.
Concept RNA, Protozoan
Academic Article In Crystallo Selection to Establish New?RNA?Crystal?Contacts.

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