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Patrick J. Kearney

TitleAsst Professor Adjoint
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-FM General Operations

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Kearney PJ, Zhang Y, Liang M, Tan Y, Kahuno E, Conklin TL, Fagan RR, Pavchinskiy RG, Shaffer SA, Yue Z, Melikian HE. Silencing Parkinson's risk allele Rit2 sex-specifically compromises motor function and dopamine neuron viability. NPJ Parkinsons Dis. 2024 Feb 23; 10(1):41. PMID: 38395968.
      View in: PubMed
    2. Kearney PJ, Zhang Y, Tan Y, Kahuno E, Conklin TL, Fagan RR, Pavchinskiy RG, Shafer SA, Yue Z, Melikian HE. Rit2 silencing in dopamine neurons drives a Parkinsonian phenotype. bioRxiv. 2023 Nov 13. PMID: 37162843.
      View in: PubMed
    3. Cui T, Corrales-Guerrero S, Castro-Aceituno V, Nair S, Maneval DC, Monnig C, Kearney P, Ellis S, Raheja N, Raheja N, Williams TM. JNTX-101, a novel albumin-encapsulated gemcitabine prodrug, is efficacious and operates via caveolin-1-mediated endocytosis. Mol Ther Oncolytics. 2023 Sep 21; 30:181-192. PMID: 37674628.
      View in: PubMed
    4. Kearney PJ, Zhang Y, Tan Y, Kahuno E, Conklin TL, Fagan RR, Pavchinskiy RG, Shafer SA, Yue Z, Melikian HE. Rit2 silencing in dopamine neurons drives a progressive Parkinsonian phenotype. Res Sq. 2023 May 25. PMID: 37293098.
      View in: PubMed
    5. Kearney PJ, Bolden NC, Kahuno E, Conklin TL, Martin GE, Lubec G, Melikian HE. Presynaptic Gq-coupled receptors drive biphasic dopamine transporter trafficking that modulates dopamine clearance and motor function. J Biol Chem. 2023 02; 299(2):102900. PMID: 36640864.
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    6. Fagan RR, Kearney PJ, Luethi D, Bolden NC, Sitte HH, Emery P, Melikian HE. Dopaminergic Ric GTPase activity impacts amphetamine sensitivity and sleep quality in a dopamine transporter-dependent manner in Drosophila melanogaster. Mol Psychiatry. 2021 12; 26(12):7793-7802. PMID: 34471250.
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    7. Fagan RR, Kearney PJ, Melikian HE. In Situ Regulated Dopamine Transporter Trafficking: There's No Place Like Home. Neurochem Res. 2020 Jun; 45(6):1335-1343. PMID: 32146647.
      View in: PubMed
    8. Fagan RR, Kearney PJ, Sweeney CG, Luethi D, Schoot Uiterkamp FE, Schicker K, Alejandro BS, O'Connor LC, Sitte HH, Melikian HE. Dopamine transporter trafficking and Rit2 GTPase: Mechanism of action and in vivo impact. J Biol Chem. 2020 04 17; 295(16):5229-5244. PMID: 32132171.
      View in: PubMed
    9. Sweeney CG, Kearney PJ, Fagan RR, Smith LA, Bolden NC, Zhao-Shea R, Rivera IV, Kolpakova J, Xie J, Gao G, Tapper AR, Martin GE, Melikian HE. Conditional, inducible gene silencing in dopamine neurons reveals a sex-specific role for Rit2 GTPase in acute cocaine response and striatal function. Neuropsychopharmacology. 2020 01; 45(2):384-393. PMID: 31277075.
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    10. Macpherson LJ, Zaharieva EE, Kearney PJ, Alpert MH, Lin TY, Turan Z, Lee CH, Gallio M. Dynamic labelling of neural connections in multiple colours by trans-synaptic fluorescence complementation. Nat Commun. 2015 Dec 04; 6:10024. PMID: 26635273.
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    11. Frank DD, Jouandet GC, Kearney PJ, Macpherson LJ, Gallio M. Temperature representation in the Drosophila brain. Nature. 2015 Mar 19; 519(7543):358-61. PMID: 25739506.
      View in: PubMed
    12. Gabriel LR, Wu S, Kearney P, Bellvé KD, Standley C, Fogarty KE, Melikian HE. Dopamine transporter endocytic trafficking in striatal dopaminergic neurons: differential dependence on dynamin and the actin cytoskeleton. J Neurosci. 2013 Nov 06; 33(45):17836-46. PMID: 24198373.
      View in: PubMed
    13. Snyder QC, Kearney PJ. High +Gz induced acute inguinal herniation in an F-16 aircrew member: case report and review. Aviat Space Environ Med. 2002 Jan; 73(1):68-72. PMID: 11817622.
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    14. Kearney PJ, Li G. Geographic variations in crash risk of general aviation and air taxis. Aviat Space Environ Med. 2000 Jan; 71(1):19-21. PMID: 10632126.
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    15. Kearney PJ. Cases from the aerospace medicine residents' teaching file. Case #54. Fibrous dysplasia. Aviat Space Environ Med. 1993 Oct; 64(10):955-6. PMID: 8240203.
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