Multi-omics and biochemical reconstitution reveal CDK7-dependent mechanisms controlling RNA polymerase II function at gene 5'- and 3' ends.
Luyties O, Sanford L, Rodino J, Nagel M, Jones T, Rimel JK, Ebmeier CC, Palacio M, Shelby GS, Cozzolino K, Brennan F, Hartzog A, Saucedo MB, Watts LP, Spencer S, Kugel JF, Dowell RD, Taatjes DJ. Multi-omics and biochemical reconstitution reveal CDK7-dependent mechanisms controlling RNA polymerase II function at gene 5'- and 3' ends. Cell Rep. 2025 Jul 22; 44(7):115904.