 Connection
Gregory Downey to Fibroblasts
This is a "connection" page, showing publications Gregory Downey has written about Fibroblasts.
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Connection Strength |
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1.839 |
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Aschner Y, Nelson M, Brenner M, Roybal H, Beke K, Meador C, Foster D, Correll KA, Reynolds PR, Anderson K, Redente EF, Matsuda J, Riches DWH, Groshong SD, Pozzi A, Sap J, Wang Q, Rajshankar D, McCulloch CAG, Zemans RL, Downey GP. Protein tyrosine phosphatase-a amplifies transforming growth factor-?-dependent profibrotic signaling in lung fibroblasts. Am J Physiol Lung Cell Mol Physiol. 2020 08 01; 319(2):L294-L311.
Score: 0.531
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Aschner Y, Khalifah AP, Briones N, Yamashita C, Dolgonos L, Young SK, Campbell MN, Riches DW, Redente EF, Janssen WJ, Henson PM, Sap J, Vacaresse N, Kapus A, McCulloch CA, Zemans RL, Downey GP. Protein tyrosine phosphatase a mediates profibrotic signaling in lung fibroblasts through TGF-? responsiveness. Am J Pathol. 2014 May; 184(5):1489-502.
Score: 0.345
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Herrera Abreu MT, Wang Q, Vachon E, Suzuki T, Chow CW, Wang Y, Hong O, Villar J, McCulloch CA, Downey GP. Tyrosine phosphatase SHP-2 regulates IL-1 signaling in fibroblasts through focal adhesions. J Cell Physiol. 2006 Apr; 207(1):132-43.
Score: 0.199
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Ahangari F, Becker C, Foster DG, Chioccioli M, Nelson M, Beke K, Wang X, Justet A, Adams T, Readhead B, Meador C, Correll K, Lili LN, Roybal HM, Rose KA, Ding S, Barnthaler T, Briones N, DeIuliis G, Schupp JC, Li Q, Omote N, Aschner Y, Sharma L, Kopf KW, Magnusson B, Hicks R, Backmark A, Dela Cruz CS, Rosas I, Cousens LP, Dudley JT, Kaminski N, Downey GP. Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis. Am J Respir Crit Care Med. 2022 12 15; 206(12):1463-1479.
Score: 0.158
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Wang Q, Delcorde J, Tang T, Downey GP, McCulloch CA. Regulation of IL-1 signaling through control of focal adhesion assembly. FASEB J. 2018 06; 32(6):3119-3132.
Score: 0.113
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Wang Q, Wang Y, Fritz D, Rajshankar D, Downey GP, McCulloch CA. Interactions of the protein-tyrosine phosphatase-a with the focal adhesion targeting domain of focal adhesion kinase are involved in interleukin-1 signaling in fibroblasts. J Biol Chem. 2014 Jun 27; 289(26):18427-41.
Score: 0.087
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Burnham EL, Janssen WJ, Riches DW, Moss M, Downey GP. The fibroproliferative response in acute respiratory distress syndrome: mechanisms and clinical significance. Eur Respir J. 2014 Jan; 43(1):276-85.
Score: 0.081
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Rajshankar D, Downey GP, McCulloch CA. IL-1? enhances cell adhesion to degraded fibronectin. FASEB J. 2012 Nov; 26(11):4429-44.
Score: 0.077
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Herrera Abreu MT, Penton PC, Kwok V, Vachon E, Shalloway D, Vidali L, Lee W, McCulloch CA, Downey GP. Tyrosine phosphatase PTPalpha regulates focal adhesion remodeling through Rac1 activation. Am J Physiol Cell Physiol. 2008 Apr; 294(4):C931-44.
Score: 0.056
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Sendo S, Kiosses WB, Yang S, Wu DJ, Lee DWK, Liu L, Aschner Y, Vela AJ, Downey GP, Santelli E, Bottini N. Clustering of phosphatase RPTPa promotes Src signaling and the arthritogenic action of synovial fibroblasts. Sci Signal. 2023 07 04; 16(792):eabn8668.
Score: 0.041
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MacGillivray M, Herrera-Abreu MT, Chow CW, Shek C, Wang Q, Vachon E, Feng GS, Siminovitch KA, McCulloch CA, Downey GP. The protein tyrosine phosphatase SHP-2 regulates interleukin-1-induced ERK activation in fibroblasts. J Biol Chem. 2003 Jul 18; 278(29):27190-8.
Score: 0.041
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Wang Q, Wang Y, Downey GP, Plotnikov S, McCulloch CA. A ternary complex comprising FAK, PTPa and IP3 receptor 1 functionally engages focal adhesions and the endoplasmic reticulum to mediate IL-1-induced Ca2+ signalling in fibroblasts. Biochem J. 2016 Feb 15; 473(4):397-410.
Score: 0.024
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Rajshankar D, Sima C, Wang Q, Goldberg SR, Kazembe M, Wang Y, Glogauer M, Downey GP, McCulloch CA. Role of PTPa in the destruction of periodontal connective tissues. PLoS One. 2013; 8(8):e70659.
Score: 0.021
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Wang Q, Downey GP, McCulloch CA. Focal adhesions and Ras are functionally and spatially integrated to mediate IL-1 activation of ERK. FASEB J. 2011 Oct; 25(10):3448-64.
Score: 0.018
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Wang Q, Herrera Abreu MT, Siminovitch K, Downey GP, McCulloch CA. Phosphorylation of SHP-2 regulates interactions between the endoplasmic reticulum and focal adhesions to restrict interleukin-1-induced Ca2+ signaling. J Biol Chem. 2006 Oct 13; 281(41):31093-105.
Score: 0.013
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Wang Q, Downey GP, Bajenova E, Abreu M, Kapus A, McCulloch CA. Mitochondrial function is a critical determinant of IL-1-induced ERK activation. FASEB J. 2005 May; 19(7):837-9.
Score: 0.012
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Wang Q, Downey GP, Herrera-Abreu MT, Kapus A, McCulloch CA. SHP-2 modulates interleukin-1-induced Ca2+ flux and ERK activation via phosphorylation of phospholipase Cgamma1. J Biol Chem. 2005 Mar 04; 280(9):8397-406.
Score: 0.011
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Wang Q, Downey GP, Choi C, Kapus A, McCulloch CA. IL-1 induced release of Ca2+ from internal stores is dependent on cell-matrix interactions and regulates ERK activation. FASEB J. 2003 Oct; 17(13):1898-900.
Score: 0.010
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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