 Connection
Eric Poeschla to HIV-1
This is a "connection" page, showing publications Eric Poeschla has written about HIV-1.
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Connection Strength |
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4.758 |
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Kumar S, Morrison JH, Dingli D, Poeschla E. HIV-1 Activation of Innate Immunity Depends Strongly on the Intracellular Level of TREX1 and Sensing of Incomplete Reverse Transcription Products. J Virol. 2018 08 15; 92(16).
Score: 0.390
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Fadel HJ, Morrison JH, Saenz DT, Fuchs JR, Kvaratskhelia M, Ekker SC, Poeschla EM. TALEN knockout of the PSIP1 gene in human cells: analyses of HIV-1 replication and allosteric integrase inhibitor mechanism. J Virol. 2014 Sep 01; 88(17):9704-17.
Score: 0.294
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Meehan AM, Saenz DT, Guevera R, Morrison JH, Peretz M, Fadel HJ, Hamada M, van Deursen J, Poeschla EM. A cyclophilin homology domain-independent role for Nup358 in HIV-1 infection. PLoS Pathog. 2014 Feb; 10(2):e1003969.
Score: 0.287
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Poeschla E. The importance of becoming double-stranded: Innate immunity and the kinetic model of HIV-1 central plus strand synthesis. Virology. 2013 Jun 20; 441(1):1-11.
Score: 0.270
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Fadel HJ, Saenz DT, Guevara R, von Messling V, Peretz M, Poeschla EM. Productive replication and evolution of HIV-1 in ferret cells. J Virol. 2012 Feb; 86(4):2312-22.
Score: 0.247
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Meehan AM, Saenz DT, Morrison J, Hu C, Peretz M, Poeschla EM. LEDGF dominant interference proteins demonstrate prenuclear exposure of HIV-1 integrase and synergize with LEDGF depletion to destroy viral infectivity. J Virol. 2011 Apr; 85(7):3570-83.
Score: 0.232
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Hu C, Saenz DT, Fadel HJ, Walker W, Peretz M, Poeschla EM. The HIV-1 central polypurine tract functions as a second line of defense against APOBEC3G/F. J Virol. 2010 Nov; 84(22):11981-93.
Score: 0.226
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Stern MA, Hu C, Saenz DT, Fadel HJ, Sims O, Peretz M, Poeschla EM. Productive replication of Vif-chimeric HIV-1 in feline cells. J Virol. 2010 Jul; 84(14):7378-95.
Score: 0.221
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Kemler I, Meehan A, Poeschla EM. Live-cell coimaging of the genomic RNAs and Gag proteins of two lentiviruses. J Virol. 2010 Jul; 84(13):6352-66.
Score: 0.220
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Meehan AM, Saenz DT, Morrison JH, Garcia-Rivera JA, Peretz M, Llano M, Poeschla EM. LEDGF/p75 proteins with alternative chromatin tethers are functional HIV-1 cofactors. PLoS Pathog. 2009 Jul; 5(7):e1000522.
Score: 0.209
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Llano M, Morrison J, Poeschla EM. Virological and cellular roles of the transcriptional coactivator LEDGF/p75. Curr Top Microbiol Immunol. 2009; 339:125-46.
Score: 0.201
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Poeschla EM. Integrase, LEDGF/p75 and HIV replication. Cell Mol Life Sci. 2008 May; 65(9):1403-24.
Score: 0.192
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Llano M, Saenz DT, Meehan A, Wongthida P, Peretz M, Walker WH, Teo W, Poeschla EM. An essential role for LEDGF/p75 in HIV integration. Science. 2006 Oct 20; 314(5798):461-4.
Score: 0.171
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Llano M, Kelly T, Vanegas M, Peretz M, Peterson TE, Simari RD, Poeschla EM. Blockade of human immunodeficiency virus type 1 expression by caveolin-1. J Virol. 2002 Sep; 76(18):9152-64.
Score: 0.130
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Singh PK, Li W, Bedwell GJ, Fadel HJ, Poeschla EM, Engelman AN. Allosteric Integrase Inhibitor Influences on HIV-1 Integration and Roles of LEDGF/p75 and HDGFL2 Host Factors. Viruses. 2022 08 26; 14(9).
Score: 0.129
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Francis AC, Cereseto A, Singh PK, Shi J, Poeschla E, Engelman AN, Aiken C, Melikyan GB. Localization and functions of native and eGFP-tagged capsid proteins in HIV-1 particles. PLoS Pathog. 2022 08; 18(8):e1010754.
Score: 0.129
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Rebensburg SV, Wei G, Larue RC, Lindenberger J, Francis AC, Annamalai AS, Morrison J, Shkriabai N, Huang SW, KewalRamani V, Poeschla EM, Melikyan GB, Kvaratskhelia M. Sec24C is an HIV-1 host dependency factor crucial for virus replication. Nat Microbiol. 2021 04; 6(4):435-444.
Score: 0.117
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Bester SM, Wei G, Zhao H, Adu-Ampratwum D, Iqbal N, Courouble VV, Francis AC, Annamalai AS, Singh PK, Shkriabai N, Van Blerkom P, Morrison J, Poeschla EM, Engelman AN, Melikyan GB, Griffin PR, Fuchs JR, Asturias FJ, Kvaratskhelia M. Structural and mechanistic bases for a potent HIV-1 capsid inhibitor. Science. 2020 10 16; 370(6514):360-364.
Score: 0.114
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Achuthan V, Perreira JM, Sowd GA, Puray-Chavez M, McDougall WM, Paulucci-Holthauzen A, Wu X, Fadel HJ, Poeschla EM, Multani AS, Hughes SH, Sarafianos SG, Brass AL, Engelman AN. Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration. Cell Host Microbe. 2018 09 12; 24(3):392-404.e8.
Score: 0.098
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Sowd GA, Serrao E, Wang H, Wang W, Fadel HJ, Poeschla EM, Engelman AN. A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin. Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8):E1054-63.
Score: 0.082
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Singh PK, Plumb MR, Ferris AL, Iben JR, Wu X, Fadel HJ, Luke BT, Esnault C, Poeschla EM, Hughes SH, Kvaratskhelia M, Levin HL. LEDGF/p75 interacts with mRNA splicing factors and targets HIV-1 integration to highly spliced genes. Genes Dev. 2015 Nov 01; 29(21):2287-97.
Score: 0.081
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Thierry S, Munir S, Thierry E, Subra F, Leh H, Zamborlini A, Saenz D, Levy DN, Lesbats P, Sa?b A, Parissi V, Poeschla E, Deprez E, Delelis O. Integrase inhibitor reversal dynamics indicate unintegrated HIV-1 dna initiate de novo integration. Retrovirology. 2015 Mar 12; 12:24.
Score: 0.077
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Slaughter A, Jurado KA, Deng N, Feng L, Kessl JJ, Shkriabai N, Larue RC, Fadel HJ, Patel PA, Jena N, Fuchs JR, Poeschla E, Levy RM, Engelman A, Kvaratskhelia M. The mechanism of H171T resistance reveals the importance of Nd-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase. Retrovirology. 2014 Nov 25; 11:100.
Score: 0.076
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Poeschla E, Wong-Staal F. Molecular biology of HIV: challenges for the second decade. AIDS Res Hum Retroviruses. 1994 Feb; 10(2):111-2.
Score: 0.071
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Kemler I, Saenz D, Poeschla E. Feline immunodeficiency virus Gag is a nuclear shuttling protein. J Virol. 2012 Aug; 86(16):8402-11.
Score: 0.064
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Fadel HJ, Poeschla EM. Retroviral restriction and dependency factors in primates and carnivores. Vet Immunol Immunopathol. 2011 Oct 15; 143(3-4):179-89.
Score: 0.060
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Sainski AM, Natesampillai S, Cummins NW, Bren GD, Taylor J, Saenz DT, Poeschla EM, Badley AD. The HIV-1-specific protein Casp8p41 induces death of infected cells through Bax/Bak. J Virol. 2011 Aug; 85(16):7965-75.
Score: 0.059
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Vanegas M, Llano M, Delgado S, Thompson D, Peretz M, Poeschla E. Identification of the LEDGF/p75 HIV-1 integrase-interaction domain and NLS reveals NLS-independent chromatin tethering. J Cell Sci. 2005 Apr 15; 118(Pt 8):1733-43.
Score: 0.039
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Merten CA, Stitz J, Braun G, Poeschla EM, Cichutek K, Buchholz CJ. Directed evolution of retrovirus envelope protein cytoplasmic tails guided by functional incorporation into lentivirus particles. J Virol. 2005 Jan; 79(2):834-40.
Score: 0.038
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Llano M, Vanegas M, Fregoso O, Saenz D, Chung S, Peretz M, Poeschla EM. LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes. J Virol. 2004 Sep; 78(17):9524-37.
Score: 0.037
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Nguyen KL, llano M, Akari H, Miyagi E, Poeschla EM, Strebel K, Bour S. Codon optimization of the HIV-1 vpu and vif genes stabilizes their mRNA and allows for highly efficient Rev-independent expression. Virology. 2004 Feb 20; 319(2):163-75.
Score: 0.036
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Loewen N, Fautsch MP, Peretz M, Bahler CK, Cameron JD, Johnson DH, Poeschla EM. Genetic modification of human trabecular meshwork with lentiviral vectors. Hum Gene Ther. 2001 Nov 20; 12(17):2109-19.
Score: 0.031
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Wong-Staal F, Poeschla EM, Looney DJ. A controlled, Phase 1 clinical trial to evaluate the safety and effects in HIV-1 infected humans of autologous lymphocytes transduced with a ribozyme that cleaves HIV-1 RNA. Hum Gene Ther. 1998 Nov 01; 9(16):2407-25.
Score: 0.025
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Poeschla E, Corbeau P, Wong-Staal F. Development of HIV vectors for anti-HIV gene therapy. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11395-9.
Score: 0.022
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Yu M, Poeschla E, Yamada O, Degrandis P, Leavitt MC, Heusch M, Yees JK, Wong-Staal F, Hampel A. In vitro and in vivo characterization of a second functional hairpin ribozyme against HIV-1. Virology. 1995 Jan 10; 206(1):381-6.
Score: 0.019
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Leavitt MC, Yu M, Yamada O, Kraus G, Looney D, Poeschla E, Wong-Staal F. Transfer of an anti-HIV-1 ribozyme gene into primary human lymphocytes. Hum Gene Ther. 1994 Sep; 5(9):1115-20.
Score: 0.019
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Sharma A, Slaughter A, Jena N, Feng L, Kessl JJ, Fadel HJ, Malani N, Male F, Wu L, Poeschla E, Bushman FD, Fuchs JR, Kvaratskhelia M. A new class of multimerization selective inhibitors of HIV-1 integrase. PLoS Pathog. 2014 May; 10(5):e1004171.
Score: 0.018
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Yu M, Poeschla E, Wong-Staal F. Progress towards gene therapy for HIV infection. Gene Ther. 1994 Jan; 1(1):13-26.
Score: 0.018
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Diaz-Griffero F, Kar A, Lee M, Stremlau M, Poeschla E, Sodroski J. Comparative requirements for the restriction of retrovirus infection by TRIM5alpha and TRIMCyp. Virology. 2007 Dec 20; 369(2):400-10.
Score: 0.012
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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