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Connection

Thomas Jansson to Signal Transduction

This is a "connection" page, showing publications Thomas Jansson has written about Signal Transduction.

 
Connection Strength
 
 
 
2.576
 
  1. Kelly AC, Kramer A, Rosario FJ, Powell TL, Jansson T. Inhibition of mechanistic target of rapamycin signaling decreases levels of O-GlcNAc transferase and increases serotonin release in the human placenta. Clin Sci (Lond). 2020 12 11; 134(23):3123-3136.
    View in: PubMed
    Score: 0.251
  2. Keleher MR, Erickson K, Kechris K, Yang IV, Dabelea D, Friedman JE, Boyle KE, Jansson T. Associations between the activity of placental nutrient-sensing pathways and neonatal and postnatal metabolic health: the ECHO Healthy Start cohort. Int J Obes (Lond). 2020 11; 44(11):2203-2212.
    View in: PubMed
    Score: 0.240
  3. Rosario FJ, Powell TL, Jansson T. Activation of placental insulin and mTOR signaling in a mouse model of maternal obesity associated with fetal overgrowth. Am J Physiol Regul Integr Comp Physiol. 2016 Jan 01; 310(1):R87-93.
    View in: PubMed
    Score: 0.176
  4. Kavitha JV, Rosario FJ, Nijland MJ, McDonald TJ, Wu G, Kanai Y, Powell TL, Nathanielsz PW, Jansson T. Down-regulation of placental mTOR, insulin/IGF-I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon. FASEB J. 2014 Mar; 28(3):1294-305.
    View in: PubMed
    Score: 0.155
  5. Roos S, Jansson N, Palmberg I, Säljö K, Powell TL, Jansson T. Mammalian target of rapamycin in the human placenta regulates leucine transport and is down-regulated in restricted fetal growth. J Physiol. 2007 Jul 01; 582(Pt 1):449-59.
    View in: PubMed
    Score: 0.098
  6. Francis EC, Boyle KE, Gyllenhammer LE, Dabelea D, Jansson T, Perng W. Placental insulin-mTOR and stress-inflammatory signaling patterns are associated with childhood adiposity. BMC Med. 2026 05 08; 24(1).
    View in: PubMed
    Score: 0.091
  7. Rosario FJ, Shimada H, Fredrick SBJ, Barentsen K, Powell TL, Urschitz J, Brown TL, Brown L, Jansson T. Trophoblast-specific overexpression of Slc7a5 increases fetal amino acid availability and hepatic mTOR signalling and causes increased fetal growth. J Physiol. 2026 Mar; 604(5):2276-2301.
    View in: PubMed
    Score: 0.090
  8. Rosario FJ, Urschitz J, Razavy H, Elston M, Powell TL, Jansson T. PiggyBac transposase-mediated inducible trophoblast-specific knockdown of Mtor decreases placental nutrient transport and fetal growth. Clin Sci (Lond). 2025 07 31; 139(14):825-845.
    View in: PubMed
    Score: 0.087
  9. Bidne KL, Erickson KE, Powell TL, Jansson T. Mechanistic target of rapamycin signaling activity in the human placenta across gestation and in maternal obesity?. Biol Reprod. 2025 03 16; 112(3):540-549.
    View in: PubMed
    Score: 0.084
  10. Dumolt JH, Rosario FJ, Barentsen K, Urschitz J, Powell TL, Jansson T. Trophoblast-specific overexpression of adiponectin receptor 2 causes fetal growth restriction in pregnant mice. FASEB J. 2024 10 15; 38(19):e70100.
    View in: PubMed
    Score: 0.082
  11. Nandi P, Jang CE, Biggar K, Halari CD, Jansson T, Gupta MB. Mechanistic Target of Rapamycin Complex 1 Signaling Links Hypoxia to Increased IGFBP-1 Phosphorylation in Primary Human Decidualized Endometrial Stromal Cells. Biomolecules. 2021 09 18; 11(9).
    View in: PubMed
    Score: 0.066
  12. Vaughan OR, Powell TL, Jansson T. Glucocorticoid regulation of amino acid transport in primary human trophoblast cells. J Mol Endocrinol. 2019 11; 63(4):239-248.
    View in: PubMed
    Score: 0.058
  13. Gupta MB, Jansson T. Novel roles of mechanistic target of rapamycin signaling in regulating fetal growth?. Biol Reprod. 2019 04 01; 100(4):872-884.
    View in: PubMed
    Score: 0.056
  14. Vaughan OR, Powell TL, Jansson T. Apelin is a novel regulator of human trophoblast amino acid transport. Am J Physiol Endocrinol Metab. 2019 05 01; 316(5):E810-E816.
    View in: PubMed
    Score: 0.056
  15. Gupta MB, Abu Shehab M, Nygard K, Biggar K, Singal SS, Santoro N, Powell TL, Jansson T. IUGR Is Associated With Marked Hyperphosphorylation of Decidual and Maternal Plasma IGFBP-1. J Clin Endocrinol Metab. 2019 02 01; 104(2):408-422.
    View in: PubMed
    Score: 0.055
  16. Chassen S, Jansson T. Complex, coordinated and highly regulated changes in placental signaling and nutrient transport capacity in IUGR. Biochim Biophys Acta Mol Basis Dis. 2020 02 01; 1866(2):165373.
    View in: PubMed
    Score: 0.055
  17. Rosario FJ, Gupta MB, Myatt L, Powell TL, Glenn JP, Cox L, Jansson T. Mechanistic Target of Rapamycin Complex 1 Promotes the Expression of Genes Encoding Electron Transport Chain Proteins and Stimulates Oxidative Phosphorylation in Primary Human Trophoblast Cells by Regulating Mitochondrial Biogenesis. Sci Rep. 2019 01 22; 9(1):246.
    View in: PubMed
    Score: 0.055
  18. Rosario FJ, Nathanielsz PW, Powell TL, Jansson T. Maternal folate deficiency causes inhibition of mTOR signaling, down-regulation of placental amino acid transporters and fetal growth restriction in mice. Sci Rep. 2017 06 21; 7(1):3982.
    View in: PubMed
    Score: 0.049
  19. Silva E, Rosario FJ, Powell TL, Jansson T. Mechanistic Target of Rapamycin Is a Novel Molecular Mechanism Linking Folate Availability and Cell Function. J Nutr. 2017 07; 147(7):1237-1242.
    View in: PubMed
    Score: 0.049
  20. Vaughan OR, Rosario FJ, Powell TL, Jansson T. Regulation of Placental Amino Acid Transport and Fetal Growth. Prog Mol Biol Transl Sci. 2017; 145:217-251.
    View in: PubMed
    Score: 0.048
  21. Dimasuay KG, Aitken EH, Rosario F, Njie M, Glazier J, Rogerson SJ, Fowkes FJ, Beeson JG, Powell T, Jansson T, Boeuf P. Inhibition of placental mTOR signaling provides a link between placental malaria and reduced birthweight. BMC Med. 2017 Jan 03; 15(1):1.
    View in: PubMed
    Score: 0.048
  22. Chen YY, Powell TL, Jansson T. 1,25-Dihydroxy vitamin D3 stimulates system A amino acid transport in primary human trophoblast cells. Mol Cell Endocrinol. 2017 02 15; 442:90-97.
    View in: PubMed
    Score: 0.048
  23. Rosario FJ, Powell TL, Jansson T. Mechanistic target of rapamycin (mTOR) regulates trophoblast folate uptake by modulating the cell surface expression of FR-a and the RFC. Sci Rep. 2016 08 26; 6:31705.
    View in: PubMed
    Score: 0.047
  24. Rosario FJ, Dimasuay KG, Kanai Y, Powell TL, Jansson T. Regulation of amino acid transporter trafficking by mTORC1 in primary human trophoblast cells is mediated by the ubiquitin ligase Nedd4-2. Clin Sci (Lond). 2016 Apr 01; 130(7):499-512.
    View in: PubMed
    Score: 0.044
  25. Chen YY, Rosario FJ, Shehab MA, Powell TL, Gupta MB, Jansson T. Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR. Clin Sci (Lond). 2015 Dec; 129(12):1131-41.
    View in: PubMed
    Score: 0.044
  26. Gaccioli F, White V, Capobianco E, Powell TL, Jawerbaum A, Jansson T. Maternal overweight induced by a diet with high content of saturated fat activates placental mTOR and eIF2alpha signaling and increases fetal growth in rats. Biol Reprod. 2013 Oct; 89(4):96.
    View in: PubMed
    Score: 0.038
  27. Jansson T, Powell TL. Role of placental nutrient sensing in developmental programming. Clin Obstet Gynecol. 2013 Sep; 56(3):591-601.
    View in: PubMed
    Score: 0.038
  28. Rosario FJ, Kanai Y, Powell TL, Jansson T. Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells. J Physiol. 2013 Feb 01; 591(3):609-25.
    View in: PubMed
    Score: 0.036
  29. Rosario FJ, Jansson N, Kanai Y, Prasad PD, Powell TL, Jansson T. Maternal protein restriction in the rat inhibits placental insulin, mTOR, and STAT3 signaling and down-regulates placental amino acid transporters. Endocrinology. 2011 Mar; 152(3):1119-29.
    View in: PubMed
    Score: 0.032
  30. Jones HN, Jansson T, Powell TL. Full-length adiponectin attenuates insulin signaling and inhibits insulin-stimulated amino Acid transport in human primary trophoblast cells. Diabetes. 2010 May; 59(5):1161-70.
    View in: PubMed
    Score: 0.030
  31. Roos S, Powell TL, Jansson T. Placental mTOR links maternal nutrient availability to fetal growth. Biochem Soc Trans. 2009 Feb; 37(Pt 1):295-8.
    View in: PubMed
    Score: 0.028
  32. Jansson N, Pettersson J, Haafiz A, Ericsson A, Palmberg I, Tranberg M, Ganapathy V, Powell TL, Jansson T. Down-regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in rats fed a low protein diet. J Physiol. 2006 Nov 01; 576(Pt 3):935-46.
    View in: PubMed
    Score: 0.024
  33. Shimada H, Sakuragi T, Barentsen K, Erickson K, Urschitz J, Powell TL, Jansson T, Rosario FJ. Placental mitochondrial respiration is inhibited in mice with trophoblast specific AdipoR2 overexpression. Free Radic Biol Med. 2026 Feb 01; 243:276-290.
    View in: PubMed
    Score: 0.022
  34. Kramer A, Vaughan OR, Barentsen K, Urschitz J, Powell TL, Jansson T, Rosario FJ. Lentivirus-Mediated Trophoblast-Specific Deptor Knockdown Increases Transplacental System A and System L Amino Acid Transport and Fetal Growth in Mice. Function (Oxf). 2025 03 24; 6(2).
    View in: PubMed
    Score: 0.021
  35. Kramer AC, Jansson T, Bale TL, Powell TL. Maternal-fetal cross-talk via the placenta: influence on offspring development and metabolism. Development. 2023 10 15; 150(20).
    View in: PubMed
    Score: 0.019
  36. Francis EC, Dabelea D, Boyle KE, Jansson T, Perng W. Maternal Diet Quality Is Associated with Placental Proteins in the Placental Insulin/Growth Factor, Environmental Stress, Inflammation, and mTOR Signaling Pathways: The Healthy Start ECHO Cohort. J Nutr. 2022 03 03; 152(3):816-825.
    View in: PubMed
    Score: 0.017
  37. Abu Shehab M, Biggar K, Kakadia JH, Dhruv M, Jain B, Nandi P, Nygard K, Jansson T, Gupta MB. Inhibition of decidual IGF-1 signaling in response to hypoxia and leucine deprivation is mediated by mTOR and AAR pathways and increased IGFBP-1 phosphorylation. Mol Cell Endocrinol. 2020 07 15; 512:110865.
    View in: PubMed
    Score: 0.015
  38. Jayabalan N, Lai A, Ormazabal V, Adam S, Guanzon D, Palma C, Scholz-Romero K, Lim R, Jansson T, McIntyre HD, Lappas M, Salomon C. Adipose Tissue Exosomal Proteomic Profile Reveals a Role on Placenta Glucose Metabolism in Gestational Diabetes Mellitus. J Clin Endocrinol Metab. 2019 05 01; 104(5):1735-1752.
    View in: PubMed
    Score: 0.014
  39. Capobianco E, Gomez Ribot D, Fornes D, Powell TL, Levieux C, Jansson T, Jawerbaum A. Diet Enriched with Olive Oil Attenuates Placental Dysfunction in Rats with Gestational Diabetes Induced by Intrauterine Programming. Mol Nutr Food Res. 2018 10; 62(19):e1800263.
    View in: PubMed
    Score: 0.013
  40. Roberti SL, Higa R, White V, Powell TL, Jansson T, Jawerbaum A. Critical role of mTOR, PPAR? and PPARd signaling in regulating early pregnancy decidual function, embryo viability and feto-placental growth. Mol Hum Reprod. 2018 06 01; 24(6):327-340.
    View in: PubMed
    Score: 0.013
  41. Singal SS, Nygard K, Dhruv MR, Biggar K, Shehab MA, Li SS, Jansson T, Gupta MB. Co-Localization of Insulin-Like Growth Factor Binding Protein-1, Casein Kinase-2ß, and Mechanistic Target of Rapamycin in Human Hepatocellular Carcinoma Cells as Demonstrated by Dual Immunofluorescence and in Situ Proximity Ligation Assay. Am J Pathol. 2018 01; 188(1):111-124.
    View in: PubMed
    Score: 0.013
  42. Capobianco E, Fornes D, Linenberg I, Powell TL, Jansson T, Jawerbaum A. A novel rat model of gestational diabetes induced by intrauterine programming is associated with alterations in placental signaling and fetal overgrowth. Mol Cell Endocrinol. 2016 Feb 15; 422:221-232.
    View in: PubMed
    Score: 0.011
  43. Damerill I, Biggar KK, Abu Shehab M, Li SS, Jansson T, Gupta MB. Hypoxia Increases IGFBP-1 Phosphorylation Mediated by mTOR Inhibition. Mol Endocrinol. 2016 Feb; 30(2):201-16.
    View in: PubMed
    Score: 0.011
  44. Malkani N, Jansson T, Gupta MB. IGFBP-1 hyperphosphorylation in response to leucine deprivation is mediated by the AAR pathway. Mol Cell Endocrinol. 2015 Sep 05; 412:182-95.
    View in: PubMed
    Score: 0.011
  45. Lager S, Jansson T, Powell TL. Differential regulation of placental amino acid transport by saturated and unsaturated fatty acids. Am J Physiol Cell Physiol. 2014 Oct 15; 307(8):C738-44.
    View in: PubMed
    Score: 0.010
  46. Aye IL, Gao X, Weintraub ST, Jansson T, Powell TL. Adiponectin inhibits insulin function in primary trophoblasts by PPARa-mediated ceramide synthesis. Mol Endocrinol. 2014 Apr; 28(4):512-24.
    View in: PubMed
    Score: 0.010
  47. Lager S, Gaccioli F, Ramirez VI, Jones HN, Jansson T, Powell TL. Oleic acid stimulates system A amino acid transport in primary human trophoblast cells mediated by toll-like receptor 4. J Lipid Res. 2013 Mar; 54(3):725-733.
    View in: PubMed
    Score: 0.009
  48. Jansson N, Rosario FJ, Gaccioli F, Lager S, Jones HN, Roos S, Jansson T, Powell TL. Activation of placental mTOR signaling and amino acid transporters in obese women giving birth to large babies. J Clin Endocrinol Metab. 2013 Jan; 98(1):105-13.
    View in: PubMed
    Score: 0.009
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