Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Connection

Thomas Jansson to TOR Serine-Threonine Kinases

This is a "connection" page, showing publications Thomas Jansson has written about TOR Serine-Threonine Kinases.

 
Connection Strength
 
 
 
7.540
 
  1. Kelly AC, Kramer A, Rosario FJ, Powell TL, Jansson T. Inhibition of mechanistic target of rapamycin signaling decreases levels of O-GlcNAc transferase and increases serotonin release in the human placenta. Clin Sci (Lond). 2020 12 11; 134(23):3123-3136.
    View in: PubMed
    Score: 0.607
  2. Gupta MB, Jansson T. Novel roles of mechanistic target of rapamycin signaling in regulating fetal growth?. Biol Reprod. 2019 04 01; 100(4):872-884.
    View in: PubMed
    Score: 0.540
  3. Silva E, Rosario FJ, Powell TL, Jansson T. Mechanistic Target of Rapamycin Is a Novel Molecular Mechanism Linking Folate Availability and Cell Function. J Nutr. 2017 07; 147(7):1237-1242.
    View in: PubMed
    Score: 0.476
  4. Rosario FJ, Powell TL, Jansson T. Mechanistic target of rapamycin (mTOR) regulates trophoblast folate uptake by modulating the cell surface expression of FR-a and the RFC. Sci Rep. 2016 08 26; 6:31705.
    View in: PubMed
    Score: 0.451
  5. Rosario FJ, Dimasuay KG, Kanai Y, Powell TL, Jansson T. Regulation of amino acid transporter trafficking by mTORC1 in primary human trophoblast cells is mediated by the ubiquitin ligase Nedd4-2. Clin Sci (Lond). 2016 Apr 01; 130(7):499-512.
    View in: PubMed
    Score: 0.428
  6. Rosario FJ, Powell TL, Jansson T. Activation of placental insulin and mTOR signaling in a mouse model of maternal obesity associated with fetal overgrowth. Am J Physiol Regul Integr Comp Physiol. 2016 Jan 01; 310(1):R87-93.
    View in: PubMed
    Score: 0.425
  7. Kavitha JV, Rosario FJ, Nijland MJ, McDonald TJ, Wu G, Kanai Y, Powell TL, Nathanielsz PW, Jansson T. Down-regulation of placental mTOR, insulin/IGF-I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon. FASEB J. 2014 Mar; 28(3):1294-305.
    View in: PubMed
    Score: 0.374
  8. Gaccioli F, White V, Capobianco E, Powell TL, Jawerbaum A, Jansson T. Maternal overweight induced by a diet with high content of saturated fat activates placental mTOR and eIF2alpha signaling and increases fetal growth in rats. Biol Reprod. 2013 Oct; 89(4):96.
    View in: PubMed
    Score: 0.370
  9. Rosario FJ, Kanai Y, Powell TL, Jansson T. Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells. J Physiol. 2013 Feb 01; 591(3):609-25.
    View in: PubMed
    Score: 0.347
  10. Rosario FJ, Jansson N, Kanai Y, Prasad PD, Powell TL, Jansson T. Maternal protein restriction in the rat inhibits placental insulin, mTOR, and STAT3 signaling and down-regulates placental amino acid transporters. Endocrinology. 2011 Mar; 152(3):1119-29.
    View in: PubMed
    Score: 0.306
  11. Rosario FJ, Urschitz J, Powell TL, Brown TL, Jansson T. Overexpression of the LAT1 in primary human trophoblast cells increases the uptake of essential amino acids and activates mTOR signaling. Clin Sci (Lond). 2023 11 15; 137(21):1651-1664.
    View in: PubMed
    Score: 0.186
  12. Dumolt JH, Rosario FJ, Kramer AC, Horwitz S, Powell TL, Jansson T. Maternal glucagon-like peptide-1 is positively associated with fetal growth in pregnancies complicated with obesity. Clin Sci (Lond). 2023 04 26; 137(8):663-678.
    View in: PubMed
    Score: 0.179
  13. Rosario FJ, Chopra A, Biggar K, Powell TL, Gupta MB, Jansson T. Placental Remote Control of Fetal Metabolism: Trophoblast mTOR Signaling Regulates Liver IGFBP-1 Phosphorylation and IGF-1 Bioavailability. Int J Mol Sci. 2023 Apr 14; 24(8).
    View in: PubMed
    Score: 0.178
  14. Kelly AC, J Rosario F, Chan J, Cox LA, Powell TL, Jansson T. Transcriptomic responses are sex-dependent in the skeletal muscle and liver in offspring of obese mice. Am J Physiol Endocrinol Metab. 2022 Oct 01; 323(4):E336-E353.
    View in: PubMed
    Score: 0.170
  15. Dumolt JH, Powell TL, Jansson T. Placental Function and the Development of Fetal Overgrowth and Fetal Growth Restriction. Obstet Gynecol Clin North Am. 2021 Jun; 48(2):247-266.
    View in: PubMed
    Score: 0.157
  16. Higa R, Rosario FJ, Powell TL, Jansson T, Jawerbaum A. Inhibition of MTOR signaling impairs rat embryo organogenesis by affecting folate availability. Reproduction. 2021 04; 161(4):365-373.
    View in: PubMed
    Score: 0.155
  17. Keleher MR, Erickson K, Kechris K, Yang IV, Dabelea D, Friedman JE, Boyle KE, Jansson T. Associations between the activity of placental nutrient-sensing pathways and neonatal and postnatal metabolic health: the ECHO Healthy Start cohort. Int J Obes (Lond). 2020 11; 44(11):2203-2212.
    View in: PubMed
    Score: 0.145
  18. Gupta MB, Abu Shehab M, Nygard K, Biggar K, Singal SS, Santoro N, Powell TL, Jansson T. IUGR Is Associated With Marked Hyperphosphorylation of Decidual and Maternal Plasma IGFBP-1. J Clin Endocrinol Metab. 2019 02 01; 104(2):408-422.
    View in: PubMed
    Score: 0.133
  19. Roberti SL, Higa R, White V, Powell TL, Jansson T, Jawerbaum A. Critical role of mTOR, PPAR? and PPARd signaling in regulating early pregnancy decidual function, embryo viability and feto-placental growth. Mol Hum Reprod. 2018 06 01; 24(6):327-340.
    View in: PubMed
    Score: 0.127
  20. Capobianco E, Fornes D, Roberti SL, Powell TL, Jansson T, Jawerbaum A. Supplementation with polyunsaturated fatty acids in pregnant rats with mild diabetes normalizes placental PPAR? and mTOR signaling in female offspring developing gestational diabetes. J Nutr Biochem. 2018 03; 53:39-47.
    View in: PubMed
    Score: 0.123
  21. Singal SS, Nygard K, Dhruv MR, Biggar K, Shehab MA, Li SS, Jansson T, Gupta MB. Co-Localization of Insulin-Like Growth Factor Binding Protein-1, Casein Kinase-2?, and Mechanistic Target of Rapamycin in Human Hepatocellular Carcinoma Cells as Demonstrated by Dual Immunofluorescence and in Situ Proximity Ligation Assay. Am J Pathol. 2018 01; 188(1):111-124.
    View in: PubMed
    Score: 0.122
  22. Rosario FJ, Nathanielsz PW, Powell TL, Jansson T. Maternal folate deficiency causes inhibition of mTOR signaling, down-regulation of placental amino acid transporters and fetal growth restriction in mice. Sci Rep. 2017 06 21; 7(1):3982.
    View in: PubMed
    Score: 0.119
  23. Dimasuay KG, Aitken EH, Rosario F, Njie M, Glazier J, Rogerson SJ, Fowkes FJ, Beeson JG, Powell T, Jansson T, Boeuf P. Inhibition of placental mTOR signaling provides a link between placental malaria and reduced birthweight. BMC Med. 2017 Jan 03; 15(1):1.
    View in: PubMed
    Score: 0.115
  24. Chen YY, Powell TL, Jansson T. 1,25-Dihydroxy vitamin D3 stimulates system A amino acid transport in primary human trophoblast cells. Mol Cell Endocrinol. 2017 02 15; 442:90-97.
    View in: PubMed
    Score: 0.115
  25. Capobianco E, Fornes D, Linenberg I, Powell TL, Jansson T, Jawerbaum A. A novel rat model of gestational diabetes induced by intrauterine programming is associated with alterations in placental signaling and fetal overgrowth. Mol Cell Endocrinol. 2016 Feb 15; 422:221-232.
    View in: PubMed
    Score: 0.108
  26. Damerill I, Biggar KK, Abu Shehab M, Li SS, Jansson T, Gupta MB. Hypoxia Increases IGFBP-1 Phosphorylation Mediated by mTOR Inhibition. Mol Endocrinol. 2016 Feb; 30(2):201-16.
    View in: PubMed
    Score: 0.108
  27. Aye IL, Rosario FJ, Powell TL, Jansson T. Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth. Proc Natl Acad Sci U S A. 2015 Oct 13; 112(41):12858-63.
    View in: PubMed
    Score: 0.106
  28. Chen YY, Rosario FJ, Shehab MA, Powell TL, Gupta MB, Jansson T. Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR. Clin Sci (Lond). 2015 Dec; 129(12):1131-41.
    View in: PubMed
    Score: 0.106
  29. Abu Shehab M, Damerill I, Shen T, Rosario FJ, Nijland M, Nathanielsz PW, Kamat A, Jansson T, Gupta MB. Liver mTOR controls IGF-I bioavailability by regulation of protein kinase CK2 and IGFBP-1 phosphorylation in fetal growth restriction. Endocrinology. 2014 Apr; 155(4):1327-39.
    View in: PubMed
    Score: 0.094
  30. Lager S, Gaccioli F, Ramirez VI, Jones HN, Jansson T, Powell TL. Oleic acid stimulates system A amino acid transport in primary human trophoblast cells mediated by toll-like receptor 4. J Lipid Res. 2013 Mar; 54(3):725-733.
    View in: PubMed
    Score: 0.087
  31. Jansson N, Rosario FJ, Gaccioli F, Lager S, Jones HN, Roos S, Jansson T, Powell TL. Activation of placental mTOR signaling and amino acid transporters in obese women giving birth to large babies. J Clin Endocrinol Metab. 2013 Jan; 98(1):105-13.
    View in: PubMed
    Score: 0.087
  32. Rosario FJ, Schumacher MA, Jiang J, Kanai Y, Powell TL, Jansson T. Chronic maternal infusion of full-length adiponectin in pregnant mice down-regulates placental amino acid transporter activity and expression and decreases fetal growth. J Physiol. 2012 Mar 15; 590(6):1495-509.
    View in: PubMed
    Score: 0.082
  33. Roos S, Powell TL, Jansson T. Placental mTOR links maternal nutrient availability to fetal growth. Biochem Soc Trans. 2009 Feb; 37(Pt 1):295-8.
    View in: PubMed
    Score: 0.067
  34. Roos S, Jansson N, Palmberg I, S?lj? K, Powell TL, Jansson T. Mammalian target of rapamycin in the human placenta regulates leucine transport and is down-regulated in restricted fetal growth. J Physiol. 2007 Jul 01; 582(Pt 1):449-59.
    View in: PubMed
    Score: 0.059
  35. Jansson N, Pettersson J, Haafiz A, Ericsson A, Palmberg I, Tranberg M, Ganapathy V, Powell TL, Jansson T. Down-regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in rats fed a low protein diet. J Physiol. 2006 Nov 01; 576(Pt 3):935-46.
    View in: PubMed
    Score: 0.057
  36. Francis EC, Dabelea D, Boyle KE, Jansson T, Perng W. Maternal Diet Quality Is Associated with Placental Proteins in the Placental Insulin/Growth Factor, Environmental Stress, Inflammation, and mTOR Signaling Pathways: The Healthy Start ECHO Cohort. J Nutr. 2022 03 03; 152(3):816-825.
    View in: PubMed
    Score: 0.041
  37. Kakadia JH, Jain BB, Biggar K, Sutherland A, Nygard K, Li C, Nathanielsz PW, Jansson T, Gupta MB. Hyperphosphorylation of fetal liver IGFBP-1 precedes slowing of fetal growth in nutrient-restricted baboons and may be a mechanism underlying IUGR. Am J Physiol Endocrinol Metab. 2020 09 01; 319(3):E614-E628.
    View in: PubMed
    Score: 0.037
  38. Abu Shehab M, Biggar K, Kakadia JH, Dhruv M, Jain B, Nandi P, Nygard K, Jansson T, Gupta MB. Inhibition of decidual IGF-1 signaling in response to hypoxia and leucine deprivation is mediated by mTOR and AAR pathways and increased IGFBP-1 phosphorylation. Mol Cell Endocrinol. 2020 07 15; 512:110865.
    View in: PubMed
    Score: 0.037
  39. Jessel RH, Rosario FJ, Chen YY, Erickson K, Teal SB, Kramer A, Cotton E, Ryan S, Jansson T, Powell TL. Decreased placental folate transporter expression and activity in first and second trimester in obese mothers. J Nutr Biochem. 2020 03; 77:108305.
    View in: PubMed
    Score: 0.035
  40. Capobianco E, Gomez Ribot D, Fornes D, Powell TL, Levieux C, Jansson T, Jawerbaum A. Diet Enriched with Olive Oil Attenuates Placental Dysfunction in Rats with Gestational Diabetes Induced by Intrauterine Programming. Mol Nutr Food Res. 2018 10; 62(19):e1800263.
    View in: PubMed
    Score: 0.032
  41. Malkani N, Jansson T, Gupta MB. IGFBP-1 hyperphosphorylation in response to leucine deprivation is mediated by the AAR pathway. Mol Cell Endocrinol. 2015 Sep 05; 412:182-95.
    View in: PubMed
    Score: 0.026
  42. Lager S, Jansson T, Powell TL. Differential regulation of placental amino acid transport by saturated and unsaturated fatty acids. Am J Physiol Cell Physiol. 2014 Oct 15; 307(8):C738-44.
    View in: PubMed
    Score: 0.025
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Copyright © 2024 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)