Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Connection

Laurel Lenz to Animals

This is a "connection" page, showing publications Laurel Lenz has written about Animals.

 
Connection Strength
 
 
 
0.823
 
  1. Bortell N, Aguilera ER, Lenz LL. Pulmonary insults exacerbate susceptibility to oral Listeria monocytogenes infection through the production of IL-10 by NK cells. PLoS Pathog. 2021 04; 17(4):e1009531.
    View in: PubMed
    Score: 0.039
  2. Larson SR, Bortell N, Illies A, Crisler WJ, Matsuda JL, Lenz LL. Myeloid Cell CK2 Regulates Inflammation and Resistance to Bacterial Infection. Front Immunol. 2020; 11:590266.
    View in: PubMed
    Score: 0.038
  3. Clark SE, Schmidt RL, Aguilera ER, Lenz LL. IL-10-producing NK cells exacerbate sublethal Streptococcus pneumoniae infection in the lung. Transl Res. 2020 12; 226:70-82.
    View in: PubMed
    Score: 0.037
  4. Aguilera ER, Lenz LL. Inflammation as a Modulator of Host Susceptibility to Pulmonary Influenza, Pneumococcal, and Co-Infections. Front Immunol. 2020; 11:105.
    View in: PubMed
    Score: 0.036
  5. Crisler WJ, Eshleman EM, Lenz LL. Ligand-induced IFNGR1 down-regulation calibrates myeloid cell IFN? responsiveness. Life Sci Alliance. 2019 10; 2(5).
    View in: PubMed
    Score: 0.035
  6. Clark SE, Burrack KS, Jameson SC, Hamilton SE, Lenz LL. NK Cell IL-10 Production Requires IL-15 and IL-10 Driven STAT3 Activation. Front Immunol. 2019; 10:2087.
    View in: PubMed
    Score: 0.035
  7. Alper S, Lenz LL. Editorial overview: Tuning the innate immune response to pathogens. Curr Opin Immunol. 2018 10; 54:vi-ix.
    View in: PubMed
    Score: 0.032
  8. Crisler WJ, Lenz LL. Crosstalk between type I and II interferons in regulation of myeloid cell responses during bacterial infection. Curr Opin Immunol. 2018 10; 54:35-41.
    View in: PubMed
    Score: 0.032
  9. Clark SE, Schmidt RL, McDermott DS, Lenz LL. A Batf3/Nlrp3/IL-18 Axis Promotes Natural Killer Cell IL-10 Production during Listeria monocytogenes Infection. Cell Rep. 2018 05 29; 23(9):2582-2594.
    View in: PubMed
    Score: 0.032
  10. Eshleman EM, Delgado C, Kearney SJ, Friedman RS, Lenz LL. Down regulation of macrophage IFNGR1 exacerbates systemic L. monocytogenes infection. PLoS Pathog. 2017 May; 13(5):e1006388.
    View in: PubMed
    Score: 0.029
  11. Clark SE, Filak HC, Guthrie BS, Schmidt RL, Jamieson A, Merkel P, Knight V, Cole CM, Raulet DH, Lenz LL. Bacterial Manipulation of NK Cell Regulatory Activity Increases Susceptibility to Listeria monocytogenes Infection. PLoS Pathog. 2016 06; 12(6):e1005708.
    View in: PubMed
    Score: 0.028
  12. Kearney SJ, Delgado C, Eshleman EM, Hill KK, O'Connor BP, Lenz LL. Type I IFNs downregulate myeloid cell IFN-? receptor by inducing recruitment of an early growth response 3/NGFI-A binding protein 1 complex that silences ifngr1 transcription. J Immunol. 2013 Sep 15; 191(6):3384-92.
    View in: PubMed
    Score: 0.023
  13. Kearney S, Delgado C, Lenz LL. Differential effects of type I and II interferons on myeloid cells and resistance to intracellular bacterial infections. Immunol Res. 2013 Mar; 55(1-3):187-200.
    View in: PubMed
    Score: 0.022
  14. Schmidt RL, Lenz LL. Distinct licensing of IL-18 and IL-1? secretion in response to NLRP3 inflammasome activation. PLoS One. 2012; 7(9):e45186.
    View in: PubMed
    Score: 0.021
  15. Williams MA, Schmidt RL, Lenz LL. Early events regulating immunity and pathogenesis during Listeria monocytogenes infection. Trends Immunol. 2012 Oct; 33(10):488-95.
    View in: PubMed
    Score: 0.021
  16. Cole C, Thomas S, Filak H, Henson PM, Lenz LL. Nitric oxide increases susceptibility of Toll-like receptor-activated macrophages to spreading Listeria monocytogenes. Immunity. 2012 May 25; 36(5):807-20.
    View in: PubMed
    Score: 0.021
  17. Rayamajhi M, Delgado C, Condon TV, Riches DW, Lenz LL. Lung B cells promote early pathogen dissemination and hasten death from inhalation anthrax. Mucosal Immunol. 2012 Jul; 5(4):444-54.
    View in: PubMed
    Score: 0.021
  18. Schmidt RL, Filak HC, Lemon JD, Potter TA, Lenz LL. A LysM and SH3-domain containing region of the Listeria monocytogenes p60 protein stimulates accessory cells to promote activation of host NK cells. PLoS Pathog. 2011 Nov; 7(11):e1002368.
    View in: PubMed
    Score: 0.020
  19. Jin L, Hill KK, Filak H, Mogan J, Knowles H, Zhang B, Perraud AL, Cambier JC, Lenz LL. MPYS is required for IFN response factor 3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers cyclic-di-AMP and cyclic-di-GMP. J Immunol. 2011 Sep 01; 187(5):2595-601.
    View in: PubMed
    Score: 0.020
  20. Rayamajhi M, Redente EF, Condon TV, Gonzalez-Juarrero M, Riches DW, Lenz LL. Non-surgical intratracheal instillation of mice with analysis of lungs and lung draining lymph nodes by flow cytometry. J Vis Exp. 2011 May 02; (51).
    View in: PubMed
    Score: 0.019
  21. Rayamajhi M, Humann J, Kearney S, Hill KK, Lenz LL. Antagonistic crosstalk between type I and II interferons and increased host susceptibility to bacterial infections. Virulence. 2010 Sep-Oct; 1(5):418-22.
    View in: PubMed
    Score: 0.018
  22. Humann J, Lenz LL. Activation of naive NK cells in response to Listeria monocytogenes requires IL-18 and contact with infected dendritic cells. J Immunol. 2010 May 01; 184(9):5172-8.
    View in: PubMed
    Score: 0.018
  23. Rayamajhi M, Humann J, Penheiter K, Andreasen K, Lenz LL. Induction of IFN-alphabeta enables Listeria monocytogenes to suppress macrophage activation by IFN-gamma. J Exp Med. 2010 Feb 15; 207(2):327-37.
    View in: PubMed
    Score: 0.018
  24. Humann J, Lenz LL. Bacterial peptidoglycan degrading enzymes and their impact on host muropeptide detection. J Innate Immun. 2009; 1(2):88-97.
    View in: PubMed
    Score: 0.016
  25. Lenz LL, Huang WA, Zhou C, Li Z, Calendar R. Stable integration vector for nutrient broth-based selection of attenuated Listeria monocytogenes strains with recombinant antigen expression. Clin Vaccine Immunol. 2008 Sep; 15(9):1414-9.
    View in: PubMed
    Score: 0.016
  26. Lenz LL, Andrews-Polymenis HL. Silencing the alarm: insights into the interaction between host and pathogen. Conference on Microbial Pathogenesis: Mechanisms of Infectious Disease. EMBO Rep. 2008 Jan; 9(1):27-32.
    View in: PubMed
    Score: 0.015
  27. Humann J, Bjordahl R, Andreasen K, Lenz LL. Expression of the p60 autolysin enhances NK cell activation and is required for listeria monocytogenes expansion in IFN-gamma-responsive mice. J Immunol. 2007 Feb 15; 178(4):2407-14.
    View in: PubMed
    Score: 0.014
  28. Lenz LL, Mohammadi S, Geissler A, Portnoy DA. SecA2-dependent secretion of autolytic enzymes promotes Listeria monocytogenes pathogenesis. Proc Natl Acad Sci U S A. 2003 Oct 14; 100(21):12432-7.
    View in: PubMed
    Score: 0.011
  29. Piper M, Van Court B, Mueller A, Watanabe S, Bickett T, Bhatia S, Darragh LB, Mayeda M, Nguyen D, Gadwa J, Knitz M, Corbo S, Morgan R, Lee JJ, Dent A, Goodman K, Messersmith W, Schulick R, Del Chiaro M, Zhu Y, Kedl RM, Lenz L, Karam SD. Targeting Treg-Expressed STAT3 Enhances NK-Mediated Surveillance of Metastasis and Improves Therapeutic Response in Pancreatic Adenocarcinoma. Clin Cancer Res. 2022 Mar 01; 28(5):1013-1026.
    View in: PubMed
    Score: 0.010
  30. Bickett TE, Knitz MW, Piper M, Oweida AJ, Gadwa J, Darragh LB, Nguyen D, Bhatia S, Bhuvane S, Phan AV, Van Court B, Corbo S, Pham T, Dent AL, Lenz L, Karam SD. Dichotomous effects of cellular expression of STAT3 on tumor growth of HNSCC. Mol Ther. 2022 03 02; 30(3):1149-1162.
    View in: PubMed
    Score: 0.010
  31. Bickett TE, Knitz M, Darragh LB, Bhatia S, Van Court B, Gadwa J, Bhuvane S, Piper M, Nguyen D, Tu H, Lenz L, Clambey ET, Barry K, Karam SD. FLT3L Release by Natural Killer Cells Enhances Response to Radioimmunotherapy in Preclinical Models of HNSCC. Clin Cancer Res. 2021 11 15; 27(22):6235-6249.
    View in: PubMed
    Score: 0.010
  32. Lenz LL, Butz EA, Bevan MJ. Requirements for bone marrow-derived antigen-presenting cells in priming cytotoxic T cell responses to intracellular pathogens. J Exp Med. 2000 Oct 16; 192(8):1135-42.
    View in: PubMed
    Score: 0.009
  33. Walker MM, Kim S, Crisler WJ, Nguyen K, Lenz LL, Cambier JC, Getahun A. Selective Loss of Responsiveness to Exogenous but Not Endogenous Cyclic-Dinucleotides in Mice Expressing STING-R231H. Front Immunol. 2020; 11:238.
    View in: PubMed
    Score: 0.009
  34. Yang C, McDermot DS, Pasricha S, Brown AS, Bedoui S, Lenz LL, van Driel IR, Hartland EL. IFN? receptor down-regulation facilitates Legionella survival in alveolar macrophages. J Leukoc Biol. 2020 02; 107(2):273-284.
    View in: PubMed
    Score: 0.009
  35. Soderborg TK, Clark SE, Mulligan CE, Janssen RC, Babcock L, Ir D, Young B, Krebs N, Lemas DJ, Johnson LK, Weir T, Lenz LL, Frank DN, Hernandez TL, Kuhn KA, D'Alessandro A, Barbour LA, El Kasmi KC, Friedman JE. The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD. Nat Commun. 2018 10 26; 9(1):4462.
    View in: PubMed
    Score: 0.008
  36. Lenz LL, Bevan MJ. CTL responses to H2-M3-restricted Listeria epitopes. Immunol Rev. 1997 Aug; 158:115-21.
    View in: PubMed
    Score: 0.007
  37. Lenz LL, Dere B, Bevan MJ. Identification of an H2-M3-restricted Listeria epitope: implications for antigen presentation by M3. Immunity. 1996 Jul; 5(1):63-72.
    View in: PubMed
    Score: 0.007
  38. Lenz LL, Bevan MJ. H2-M3 restricted presentation of Listeria monocytogenes antigens. Immunol Rev. 1996 Jun; 151:107-21.
    View in: PubMed
    Score: 0.007
  39. Mills CD, Lenz LL, Harris RA. A Breakthrough: Macrophage-Directed Cancer Immunotherapy. Cancer Res. 2016 Feb 01; 76(3):513-6.
    View in: PubMed
    Score: 0.007
  40. Kedl RM, Wysocki LJ, Janssen WJ, Born WK, Rosenbaum MD, Granowski J, Kench JA, Fong DL, Switzer LA, Cruse M, Huang H, Jakubzick CV, Kosmider B, Takeda K, Stranova TJ, Klumm RC, Delgado C, Tummala S, De Langhe S, Cambier J, Haskins K, Lenz LL, Curran-Everett D. General parity between trio and pairwise breeding of laboratory mice in static caging. J Immunol. 2014 Nov 15; 193(10):4757-60.
    View in: PubMed
    Score: 0.006
  41. Knowles H, Heizer JW, Li Y, Chapman K, Ogden CA, Andreasen K, Shapland E, Kucera G, Mogan J, Humann J, Lenz LL, Morrison AD, Perraud AL. Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes. Proc Natl Acad Sci U S A. 2011 Jul 12; 108(28):11578-83.
    View in: PubMed
    Score: 0.005
  42. Boudreau JE, Stephenson KB, Wang F, Ashkar AA, Mossman KL, Lenz LL, Rosenthal KL, Bramson JL, Lichty BD, Wan Y. IL-15 and type I interferon are required for activation of tumoricidal NK cells by virus-infected dendritic cells. Cancer Res. 2011 Apr 01; 71(7):2497-506.
    View in: PubMed
    Score: 0.005
  43. Jin L, Lenz LL, Cambier JC. Cellular reactive oxygen species inhibit MPYS induction of IFN?. PLoS One. 2010 Dec 10; 5(12):e15142.
    View in: PubMed
    Score: 0.005
  44. Noor S, Goldfine H, Tucker DE, Suram S, Lenz LL, Akira S, Uematsu S, Girotti M, Bonventre JV, Breuel K, Williams DL, Leslie CC. Activation of cytosolic phospholipase A2alpha in resident peritoneal macrophages by Listeria monocytogenes involves listeriolysin O and TLR2. J Biol Chem. 2008 Feb 22; 283(8):4744-55.
    View in: PubMed
    Score: 0.004
  45. Muraille E, Narni-Mancinelli E, Gounon P, Bassand D, Glaichenhaus N, Lenz LL, Lauvau G. Cytosolic expression of SecA2 is a prerequisite for long-term protective immunity. Cell Microbiol. 2007 Jun; 9(6):1445-54.
    View in: PubMed
    Score: 0.004
  46. Arrunategui-Correa V, Lenz L, Kim HS. CD1d-independent regulation of NKT cell migration and cytokine production upon Listeria monocytogenes infection. Cell Immunol. 2004 Nov-Dec; 232(1-2):38-48.
    View in: PubMed
    Score: 0.003
  47. Diehl GE, Yue HH, Hsieh K, Kuang AA, Ho M, Morici LA, Lenz LL, Cado D, Riley LW, Winoto A. TRAIL-R as a negative regulator of innate immune cell responses. Immunity. 2004 Dec; 21(6):877-89.
    View in: PubMed
    Score: 0.003
  48. Ploss A, Lauvau G, Contos B, Kerksiek KM, Guirnalda PD, Leiner I, Lenz LL, Bevan MJ, Pamer EG. Promiscuity of MHC class Ib-restricted T cell responses. J Immunol. 2003 Dec 01; 171(11):5948-55.
    View in: PubMed
    Score: 0.003
  49. Auerbuch V, Lenz LL, Portnoy DA. Development of a competitive index assay to evaluate the virulence of Listeria monocytogenes actA mutants during primary and secondary infection of mice. Infect Immun. 2001 Sep; 69(9):5953-7.
    View in: PubMed
    Score: 0.002
  50. Princiotta MF, Lenz LL, Bevan MJ, Staerz UD. H2-M3 restricted presentation of a Listeria-derived leader peptide. J Exp Med. 1998 May 18; 187(10):1711-9.
    View in: PubMed
    Score: 0.002
  51. Harty JT, Lenz LL, Bevan MJ. Primary and secondary immune responses to Listeria monocytogenes. Curr Opin Immunol. 1996 Aug; 8(4):526-30.
    View in: PubMed
    Score: 0.002
  52. Fattaey A, Lenz L, Consigli RA. Production and characterization of monoclonal antibodies to budgerigar fledgling disease virus major capsid protein VP. Avian Dis. 1992 Jul-Sep; 36(3):543-53.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Copyright © 2025 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)