Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Connection

Tamir Kanias to Blood Preservation

This is a "connection" page, showing publications Tamir Kanias has written about Blood Preservation.

 
Connection Strength
 
 
 
6.495
 
  1. Tran J, Jackman RP, Muench MO, Hazegh K, Bean SW, Thomas KA, Fang F, Page G, O'Connor K, Roubinian NH, Anawalt BD, Kanias T. Testosterone supplementation increases red blood cell susceptibility to oxidative stress, decreases membrane deformability, and decreases survival after cold storage and transfusion. Transfusion. 2024 08; 64(8):1469-1480.
    View in: PubMed
    Score: 0.617
  2. Hazegh K, Fang F, Bravo MD, Tran JQ, Muench MO, Jackman RP, Roubinian N, Bertolone L, D'Alessandro A, Dumont L, Page GP, Kanias T. Blood donor obesity is associated with changes in red blood cell metabolism and susceptibility to hemolysis in cold storage and in response to osmotic and oxidative stress. Transfusion. 2021 02; 61(2):435-448.
    View in: PubMed
    Score: 0.480
  3. Alexander K, Hazegh K, Fang F, Sinchar D, Kiss JE, Page GP, D'Alessandro A, Kanias T. Testosterone replacement therapy in blood donors modulates erythrocyte metabolism and susceptibility to hemolysis in cold storage. Transfusion. 2021 01; 61(1):108-123.
    View in: PubMed
    Score: 0.479
  4. Kanias T, Busch MP. Diversity in a blood bag: application of omics technologies to inform precision Transfusion Medicine. Blood Transfus. 2019 07; 17(4):258-262.
    View in: PubMed
    Score: 0.435
  5. Kanias T, Wang L, Lippert A, Kim-Shapiro DB, Gladwin MT. Red blood cell endothelial nitric oxide synthase does not modulate red blood cell storage hemolysis. Transfusion. 2013 May; 53(5):981-9.
    View in: PubMed
    Score: 0.272
  6. Kanias T, Gladwin MT. Nitric oxide, hemolysis, and the red blood cell storage lesion: interactions between transfusion, donor, and recipient. Transfusion. 2012 Jul; 52(7):1388-92.
    View in: PubMed
    Score: 0.269
  7. Kanias T, Acker JP. Mechanism of hemoglobin-induced cellular injury in desiccated red blood cells. Free Radic Biol Med. 2010 Aug 15; 49(4):539-47.
    View in: PubMed
    Score: 0.232
  8. Kanias T, Acker JP. Biopreservation of red blood cells--the struggle with hemoglobin oxidation. FEBS J. 2010 Jan; 277(2):343-56.
    View in: PubMed
    Score: 0.225
  9. Deng X, Di Germanio C, Marques de Menezes EG, Milani P, Stone M, Tanner H, Bakkour SC, Chafets DM, Reese SE, Roubinian NH, Kleinman S, Kanias T, Busch MP, Earley EJ, Page GP, Nemkov T, D'Alessandro A, Norris PJ. Donor genetics and storage conditions influence mitochondrial DNA and extracellular vesicle levels in RBC units. JCI Insight. 2025 Jul 22; 10(14).
    View in: PubMed
    Score: 0.165
  10. Kanias T, George G, Sekiya J, Kelly K, Stanley C, Lee D, Finlon J, Rahman M, Gehris T, Bowen D, Barton M, Marschner S, Berg MP, Norris PJ. Optimization of biotinylation protocol for next generation studies of red blood cell survival after transfusion. Transfusion. 2025 Jul; 65(7):1360-1372.
    View in: PubMed
    Score: 0.164
  11. Zhao Y, Brandon-Coatham M, Yazdanbakhsh M, Mykhailova O, William N, Osmani R, Kanias T, Acker JP. Cold storage surpasses the impact of biological age and donor characteristics on red blood cell morphology classified by deep machine learning. Sci Rep. 2025 Mar 05; 15(1):7735.
    View in: PubMed
    Score: 0.162
  12. Mykhailova O, Brandon-Coatham M, Hemmatibardehshahi S, Yazdanbakhsh M, Olafson C, Yi QL, Kanias T, Acker JP. Donor age contributes more to the rheological properties of stored red blood cells than donor sex and biological age distribution. Blood Adv. 2025 Feb 25; 9(4):673-686.
    View in: PubMed
    Score: 0.162
  13. Kelly K, Kanias T, Leite C, Stanley C, Dumont LJ. Platelet storage in small bags as a model of platelet function in full-sized containers. Transfusion. 2025 Jan; 65(1):185-193.
    View in: PubMed
    Score: 0.160
  14. Fang F, Roubinian NH, Bean SW, Kemmler C, Page GG, Kanias T. Genetic determinants of plasma testosterone in male blood donors are associated with altered red blood cell characteristics and survival in cold storage and after transfusion. Transfus Apher Sci. 2024 12; 63(6):104017.
    View in: PubMed
    Score: 0.158
  15. Chitrakar A, Bean SM, Kanias T, Thomas KA. Stored platelet hemostatic phenotype and function is not altered when donors are on testosterone replacement therapy. Transfusion. 2024 08; 64(8):1520-1532.
    View in: PubMed
    Score: 0.155
  16. Mykhailova O, Brandon-Coatham M, Phan C, Yazdanbakhsh M, Olafson C, Yi QL, Kanias T, Acker JP. Red cell concentrates from teen male donors contain poor-quality biologically older cells. Vox Sang. 2024 May; 119(5):417-427.
    View in: PubMed
    Score: 0.151
  17. Donnenberg AD, Kim-Shapiro DB, Kanias T, Moore LR, Kiss JE, Lee JS, Xiong Z, Wang L, Triulzi DJ, Gladwin MT. Optimizing interpretation of survival studies of fresh and aged transfused biotin-labeled RBCs. Transfusion. 2023 01; 63(1):35-46.
    View in: PubMed
    Score: 0.139
  18. Fang F, Hazegh K, Mast AE, Triulzi DJ, Spencer BR, Gladwin MT, Busch MP, Kanias T, Page GP. Sex-specific genetic modifiers identified susceptibility of cold stored red blood cells to osmotic hemolysis. BMC Genomics. 2022 Mar 23; 23(1):227.
    View in: PubMed
    Score: 0.132
  19. Page GP, Kanias T, Guo YJ, Lanteri MC, Zhang X, Mast AE, Cable RG, Spencer BR, Kiss JE, Fang F, Endres-Dighe SM, Brambilla D, Nouraie M, Gordeuk VR, Kleinman S, Busch MP, Gladwin MT. Multiple-ancestry genome-wide association study identifies 27 loci associated with measures of hemolysis following blood storage. J Clin Invest. 2021 07 01; 131(13).
    View in: PubMed
    Score: 0.126
  20. D'Alessandro A, Fu X, Kanias T, Reisz JA, Culp-Hill R, Guo Y, Gladwin MT, Page G, Kleinman S, Lanteri M, Stone M, Busch MP, Zimring JC. Donor sex, age and ethnicity impact stored red blood cell antioxidant metabolism through mechanisms in part explained by glucose 6-phosphate dehydrogenase levels and activity. Haematologica. 2021 05 01; 106(5):1290-1302.
    View in: PubMed
    Score: 0.124
  21. D'Alessandro A, Fu X, Reisz JA, Kanias T, Page GP, Stone M, Kleinman S, Zimring JC, Busch M. Stored RBC metabolism as a function of caffeine levels. Transfusion. 2020 06; 60(6):1197-1211.
    View in: PubMed
    Score: 0.116
  22. Stefanoni D, Fu X, Reisz JA, Kanias T, Nemkov T, Page GP, Dumont L, Roubinian N, Stone M, Kleinman S, Busch M, Zimring JC, D'Alessandro A. Nicotine exposure increases markers of oxidant stress in stored red blood cells from healthy donor volunteers. Transfusion. 2020 06; 60(6):1160-1174.
    View in: PubMed
    Score: 0.116
  23. Bertolone L, Roy MK, Hay AM, Morrison EJ, Stefanoni D, Fu X, Kanias T, Kleinman S, Dumont LJ, Stone M, Nemkov T, Busch MP, Zimring JC, D'Alessandro A. Impact of taurine on red blood cell metabolism and implications for blood storage. Transfusion. 2020 06; 60(6):1212-1226.
    View in: PubMed
    Score: 0.116
  24. Fang F, Hazegh K, Sinchar D, Guo Y, Page GP, Mast AE, Kleinman S, Busch MP, Kanias T. Sex hormone intake in female blood donors: impact on haemolysis during cold storage and regulation of erythrocyte calcium influx by progesterone. Blood Transfus. 2019 07; 17(4):263-273.
    View in: PubMed
    Score: 0.109
  25. D'Alessandro A, Reisz JA, Zhang Y, Gehrke S, Alexander K, Kanias T, Triulzi DJ, Donadee C, Barge S, Badlam J, Jain S, Risbano MG, Gladwin MT. Effects of aged stored autologous red blood cells on human plasma metabolome. Blood Adv. 2019 03 26; 3(6):884-896.
    View in: PubMed
    Score: 0.107
  26. Stone M, Keating SM, Kanias T, Lanteri MC, Lebedeva M, Sinchar D, Hampton D, Jakub A, Rychka V, Brewer G, Bakkour S, Gefter N, Murcia K, Page GP, Endres-Dighe S, Bialkowski W, Fu X, Zimring J, Raife TJ, Kleinman S, Gladwin MT, Busch MP. Piloting and implementation of quality assessment and quality control procedures in RBC-Omics: a large multi-center study of red blood cell hemolysis during storage. Transfusion. 2019 01; 59(1):57-66.
    View in: PubMed
    Score: 0.105
  27. Kanias T, Stone M, Page GP, Guo Y, Endres-Dighe SM, Lanteri MC, Spencer BR, Cable RG, Triulzi DJ, Kiss JE, Murphy EL, Kleinman S, Gladwin MT, Busch MP, Mast AE. Frequent blood donations alter susceptibility of red blood cells to storage- and stress-induced hemolysis. Transfusion. 2019 01; 59(1):67-78.
    View in: PubMed
    Score: 0.105
  28. Reisz JA, Nemkov T, Dzieciatkowska M, Culp-Hill R, Stefanoni D, Hill RC, Yoshida T, Dunham A, Kanias T, Dumont LJ, Busch M, Eisenmesser EZ, Zimring JC, Hansen KC, D'Alessandro A. Methylation of protein aspartates and deamidated asparagines as a function of blood bank storage and oxidative stress in human red blood cells. Transfusion. 2018 12; 58(12):2978-2991.
    View in: PubMed
    Score: 0.104
  29. Kanias T, Sinchar D, Osei-Hwedieh D, Baust JJ, Jordan A, Zimring JC, Waterman HR, de Wolski KS, Acker JP, Gladwin MT. Testosterone-dependent sex differences in red blood cell hemolysis in storage, stress, and disease. Transfusion. 2016 Oct; 56(10):2571-2583.
    View in: PubMed
    Score: 0.089
  30. Osei-Hwedieh DO, Kanias T, Croix CS, Jessup M, Xiong Z, Sinchar D, Franks J, Xu Q, M Novelli E, Sertorio JT, Potoka K, Binder RJ, Basu S, Belanger AM, Kim-Shapiro DB, Triulzi D, Lee JS, Gladwin MT. Sickle Cell Trait Increases Red Blood Cell Storage Hemolysis and Post-Transfusion Clearance in Mice. EBioMedicine. 2016 Sep; 11:239-248.
    View in: PubMed
    Score: 0.089
  31. Risbano MG, Kanias T, Triulzi D, Donadee C, Barge S, Badlam J, Jain S, Belanger AM, Kim-Shapiro DB, Gladwin MT. Effects of Aged Stored Autologous Red Blood Cells on Human Endothelial Function. Am J Respir Crit Care Med. 2015 Nov 15; 192(10):1223-33.
    View in: PubMed
    Score: 0.085
  32. Huang S, Hou HW, Kanias T, Sertorio JT, Chen H, Sinchar D, Gladwin MT, Han J. Towards microfluidic-based depletion of stiff and fragile human red cells that accumulate during blood storage. Lab Chip. 2015 Jan 21; 15(2):448-58.
    View in: PubMed
    Score: 0.080
  33. Wang D, Cortés-Puch I, Sun J, Solomon SB, Kanias T, Remy KE, Feng J, Alimchandani M, Quezado M, Helms C, Perlegas A, Gladwin MT, Kim-Shapiro DB, Klein HG, Natanson C. Transfusion of older stored blood worsens outcomes in canines depending on the presence and severity of pneumonia. Transfusion. 2014 Jul; 54(7):1712-24.
    View in: PubMed
    Score: 0.076
  34. Solomon SB, Wang D, Sun J, Kanias T, Feng J, Helms CC, Solomon MA, Alimchandani M, Quezado M, Gladwin MT, Kim-Shapiro DB, Klein HG, Natanson C. Mortality increases after massive exchange transfusion with older stored blood in canines with experimental pneumonia. Blood. 2013 Feb 28; 121(9):1663-72.
    View in: PubMed
    Score: 0.070
  35. Gladwin MT, Kanias T, Kim-Shapiro DB. Hemolysis and cell-free hemoglobin drive an intrinsic mechanism for human disease. J Clin Invest. 2012 Apr; 122(4):1205-8.
    View in: PubMed
    Score: 0.066
  36. Donadee C, Raat NJ, Kanias T, Tejero J, Lee JS, Kelley EE, Zhao X, Liu C, Reynolds H, Azarov I, Frizzell S, Meyer EM, Donnenberg AD, Qu L, Triulzi D, Kim-Shapiro DB, Gladwin MT. Nitric oxide scavenging by red blood cell microparticles and cell-free hemoglobin as a mechanism for the red cell storage lesion. Circulation. 2011 Jul 26; 124(4):465-76.
    View in: PubMed
    Score: 0.063
  37. Mykhailova O, Brandon-Coatham M, Durand K, Olafson C, Xu A, Yi QL, Kanias T, Acker JP. Estimated median density identifies donor age and sex differences in red blood cell biological age. Transfusion. 2024 04; 64(4):705-715.
    View in: PubMed
    Score: 0.038
  38. Cloutier M, Cognasse F, Yokoyama APH, Hazegh K, Mykhailova O, Brandon-Coatham M, Hamzeh-Cognasse H, Kutner JM, Acker JP, Kanias T. Quality assessment of red blood cell concentrates from blood donors at the extremes of the age spectrum: The BEST collaborative study. Transfusion. 2023 08; 63(8):1506-1518.
    View in: PubMed
    Score: 0.036
  39. Lanteri MC, Kanias T, Keating S, Stone M, Guo Y, Page GP, Brambilla DJ, Endres-Dighe SM, Mast AE, Bialkowski W, D'Andrea P, Cable RG, Spencer BR, Triulzi DJ, Murphy EL, Kleinman S, Gladwin MT, Busch MP. Intradonor reproducibility and changes in hemolytic variables during red blood cell storage: results of recall phase of the REDS-III RBC-Omics study. Transfusion. 2019 01; 59(1):79-88.
    View in: PubMed
    Score: 0.026
  40. D'Alessandro A, Culp-Hill R, Reisz JA, Anderson M, Fu X, Nemkov T, Gehrke S, Zheng C, Kanias T, Guo Y, Page G, Gladwin MT, Kleinman S, Lanteri M, Stone M, Busch M, Zimring JC. Heterogeneity of blood processing and storage additives in different centers impacts stored red blood cell metabolism as much as storage time: lessons from REDS-III-Omics. Transfusion. 2019 01; 59(1):89-100.
    View in: PubMed
    Score: 0.026
  41. Endres-Dighe SM, Guo Y, Kanias T, Lanteri M, Stone M, Spencer B, Cable RG, Kiss JE, Kleinman S, Gladwin MT, Brambilla DJ, D'Andrea P, Triulzi DJ, Mast AE, Page GP, Busch MP. Blood, sweat, and tears: Red Blood Cell-Omics study objectives, design, and recruitment activities. Transfusion. 2019 01; 59(1):46-56.
    View in: PubMed
    Score: 0.026
  42. Cortés-Puch I, Remy KE, Solomon SB, Sun J, Wang D, Al-Hamad M, Kelly SM, Sinchar D, Bellavia L, Kanias T, Popovsky MA, Kim-Shapiro DB, Klein HG, Natanson C. In a canine pneumonia model of exchange transfusion, altering the age but not the volume of older red blood cells markedly alters outcome. Transfusion. 2015 Nov; 55(11):2564-75.
    View in: PubMed
    Score: 0.021
  43. Cortés-Puch I, Wang D, Sun J, Solomon SB, Remy KE, Fernandez M, Feng J, Kanias T, Bellavia L, Sinchar D, Perlegas A, Solomon MA, Kelley WE, Popovsky MA, Gladwin MT, Kim-Shapiro DB, Klein HG, Natanson C. Washing older blood units before transfusion reduces plasma iron and improves outcomes in experimental canine pneumonia. Blood. 2014 Feb 27; 123(9):1403-11.
    View in: PubMed
    Score: 0.019
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Copyright © 2026 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)