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Connection

Leslie Leinwand to Myosins

This is a "connection" page, showing publications Leslie Leinwand has written about Myosins.

 
Connection Strength
 
 
 
5.543
 
  1. Vera CD, Johnson CA, Walklate J, Adhikari A, Svicevic M, Mijailovich SM, Combs AC, Langer SJ, Ruppel KM, Spudich JA, Geeves MA, Leinwand LA. Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar properties. J Biol Chem. 2019 11 15; 294(46):17451-17462.
    View in: PubMed
    Score: 0.648
  2. Resnicow DI, Deacon JC, Warrick HM, Spudich JA, Leinwand LA. Functional diversity among a family of human skeletal muscle myosin motors. Proc Natl Acad Sci U S A. 2010 Jan 19; 107(3):1053-8.
    View in: PubMed
    Score: 0.329
  3. Armel TZ, Leinwand LA. Mutations at the same amino acid in myosin that cause either skeletal or cardiac myopathy have distinct molecular phenotypes. J Mol Cell Cardiol. 2010 May; 48(5):1007-13.
    View in: PubMed
    Score: 0.325
  4. Armel TZ, Leinwand LA. Mutations in the beta-myosin rod cause myosin storage myopathy via multiple mechanisms. Proc Natl Acad Sci U S A. 2009 Apr 14; 106(15):6291-6.
    View in: PubMed
    Score: 0.313
  5. Resnicow DI, Hooft AM, Harrison BC, Baker JE, Leinwand LA. GFP fails to inhibit actin-myosin interactions in vitro. Nat Methods. 2008 Mar; 5(3):212-3; author reply 213-4.
    View in: PubMed
    Score: 0.290
  6. Meller A, Lotthammer JM, Smith LG, Novak B, Lee LA, Kuhn CC, Greenberg L, Leinwand LA, Greenberg MJ, Bowman GR. Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains. Elife. 2023 01 27; 12.
    View in: PubMed
    Score: 0.204
  7. Lehman SJ, Crocini C, Leinwand LA. Targeting the sarcomere in inherited cardiomyopathies. Nat Rev Cardiol. 2022 06; 19(6):353-363.
    View in: PubMed
    Score: 0.192
  8. Freeman K, Colon-Rivera C, Olsson MC, Moore RL, Weinberger HD, Grupp IL, Vikstrom KL, Iaccarino G, Koch WJ, Leinwand LA. Progression from hypertrophic to dilated cardiomyopathy in mice that express a mutant myosin transgene. Am J Physiol Heart Circ Physiol. 2001 Jan; 280(1):H151-9.
    View in: PubMed
    Score: 0.177
  9. Roopnarine O, Leinwand LA. Functional analysis of myosin mutations that cause familial hypertrophic cardiomyopathy. Biophys J. 1998 Dec; 75(6):3023-30.
    View in: PubMed
    Score: 0.153
  10. Mayer DC, Leinwand LA. Sarcomeric gene expression and contractility in myofibroblasts. J Cell Biol. 1997 Dec 15; 139(6):1477-84.
    View in: PubMed
    Score: 0.143
  11. Sohn RL, Vikstrom KL, Strauss M, Cohen C, Szent-Gyorgyi AG, Leinwand LA. A 29 residue region of the sarcomeric myosin rod is necessary for filament formation. J Mol Biol. 1997 Feb 21; 266(2):317-30.
    View in: PubMed
    Score: 0.135
  12. Schiaffino S, Murgia M, Leinwand LA, Reggiani C. Letter to the editor: Comments on Stuart et al. (2016): "Myosin content of individual human muscle fibers isolated by laser capture microdissection". Am J Physiol Cell Physiol. 2016 12 01; 311(6):C1048-C1049.
    View in: PubMed
    Score: 0.133
  13. Sindhwani R, Ismail-Beigi F, Leinwand LA. Post-transcriptional regulation of rat alpha cardiac myosin heavy chain gene expression. J Biol Chem. 1994 Feb 04; 269(5):3272-6.
    View in: PubMed
    Score: 0.109
  14. Straceski AJ, Geisterfer-Lowrance A, Seidman CE, Seidman JG, Leinwand LA. Functional analysis of myosin missense mutations in familial hypertrophic cardiomyopathy. Proc Natl Acad Sci U S A. 1994 Jan 18; 91(2):589-93.
    View in: PubMed
    Score: 0.109
  15. Weiss A, Mayer DC, Leinwand LA. Diversity of myosin-based motility: multiple genes and functions. Soc Gen Physiol Ser. 1994; 49:159-71.
    View in: PubMed
    Score: 0.109
  16. Buttrick PM, Kaplan ML, Kitsis RN, Leinwand LA. Distinct behavior of cardiac myosin heavy chain gene constructs in vivo. Discordance with in vitro results. Circ Res. 1993 Jun; 72(6):1211-7.
    View in: PubMed
    Score: 0.104
  17. Vikstrom KL, Rovner AS, Saez CG, Bravo-Zehnder M, Straceski AJ, Leinwand LA. Sarcomeric myosin heavy chain expressed in nonmuscle cells forms thick filaments in the presence of substoichiometric amounts of light chains. Cell Motil Cytoskeleton. 1993; 26(3):192-204.
    View in: PubMed
    Score: 0.101
  18. Yoon SJ, Seiler SH, Kucherlapati R, Leinwand L. Organization of the human skeletal myosin heavy chain gene cluster. Proc Natl Acad Sci U S A. 1992 Dec 15; 89(24):12078-82.
    View in: PubMed
    Score: 0.101
  19. Moore JR, Leinwand L, Warshaw DM. Understanding cardiomyopathy phenotypes based on the functional impact of mutations in the myosin motor. Circ Res. 2012 Jul 20; 111(3):375-85.
    View in: PubMed
    Score: 0.098
  20. McNally EM, Bravo-Zehnder MM, Leinwand LA. Identification of sequences necessary for the association of cardiac myosin subunits. J Cell Biol. 1991 May; 113(3):585-90.
    View in: PubMed
    Score: 0.090
  21. Frankel S, Sohn R, Leinwand L. The use of sarkosyl in generating soluble protein after bacterial expression. Proc Natl Acad Sci U S A. 1991 Feb 15; 88(4):1192-6.
    View in: PubMed
    Score: 0.089
  22. McNally E, Sohn R, Frankel S, Leinwand L. Expression of myosin and actin in Escherichia coli. Methods Enzymol. 1991; 196:368-89.
    View in: PubMed
    Score: 0.088
  23. McNally EM, Kraft R, Bravo-Zehnder M, Taylor DA, Leinwand LA. Full-length rat alpha and beta cardiac myosin heavy chain sequences. Comparisons suggest a molecular basis for functional differences. J Mol Biol. 1989 Dec 05; 210(3):665-71.
    View in: PubMed
    Score: 0.082
  24. McNally EM, Gianola KM, Leinwand LA. Complete nucleotide sequence of full length cDNA for rat alpha cardiac myosin heavy chain. Nucleic Acids Res. 1989 Sep 25; 17(18):7527-8.
    View in: PubMed
    Score: 0.081
  25. Kraft R, Bravo-Zehnder M, Taylor DA, Leinwand LA. Complete nucleotide sequence of full length cDNA for rat beta cardiac myosin heavy chain. Nucleic Acids Res. 1989 Sep 25; 17(18):7529-30.
    View in: PubMed
    Score: 0.081
  26. Karsch-Mizrachi I, Travis M, Blau H, Leinwand LA. Expression and DNA sequence analysis of a human embryonic skeletal muscle myosin heavy chain gene. Nucleic Acids Res. 1989 Aug 11; 17(15):6167-79.
    View in: PubMed
    Score: 0.080
  27. Feghali R, Leinwand LA. Molecular genetic characterization of a developmentally regulated human perinatal myosin heavy chain. J Cell Biol. 1989 May; 108(5):1791-7.
    View in: PubMed
    Score: 0.079
  28. McNally EM, Buttrick PM, Leinwand LA. Ventricular myosin light chain 1 is developmentally regulated and does not change in hypertension. Nucleic Acids Res. 1989 Apr 11; 17(7):2753-67.
    View in: PubMed
    Score: 0.078
  29. McNally EM, Goodwin EB, Spudich JA, Leinwand LA. Coexpression and assembly of myosin heavy chain and myosin light chain in Escherichia coli. Proc Natl Acad Sci U S A. 1988 Oct; 85(19):7270-3.
    View in: PubMed
    Score: 0.076
  30. Goodwin EB, Szent-Gyorgyi AG, Leinwand LA. Cloning and characterization of the scallop essential and regulatory myosin light chain cDNAs. J Biol Chem. 1987 Aug 15; 262(23):11052-6.
    View in: PubMed
    Score: 0.070
  31. Saez LJ, Gianola KM, McNally EM, Feghali R, Eddy R, Shows TB, Leinwand LA. Human cardiac myosin heavy chain genes and their linkage in the genome. Nucleic Acids Res. 1987 Jul 10; 15(13):5443-59.
    View in: PubMed
    Score: 0.069
  32. Saez L, Leinwand LA. Characterization of diverse forms of myosin heavy chain expressed in adult human skeletal muscle. Nucleic Acids Res. 1986 Apr 11; 14(7):2951-69.
    View in: PubMed
    Score: 0.064
  33. DeLozanne A, Lewis M, Spudich JA, Leinwand LA. Cloning and characterization of a nonmuscle myosin heavy chain cDNA. Proc Natl Acad Sci U S A. 1985 Oct; 82(20):6807-10.
    View in: PubMed
    Score: 0.061
  34. Leinwand LA, Fournier RE, Nadal-Ginard B, Shows TB. Multigene family for sarcomeric myosin heavy chain in mouse and human DNA: localization on a single chromosome. Science. 1983 Aug 19; 221(4612):766-9.
    View in: PubMed
    Score: 0.053
  35. Leinwand LA, Saez L, McNally E, Nadal-Ginard B. Isolation and characterization of human myosin heavy chain genes. Proc Natl Acad Sci U S A. 1983 Jun; 80(12):3716-20.
    View in: PubMed
    Score: 0.052
  36. S?billon P, Bonne G, Flavigny J, Venin S, Rouche A, Fiszman M, Vikstrom K, Leinwand L, Carrier L, Schwartz K. COOH-terminal truncated human cardiac MyBP-C alters myosin filament organization. C R Acad Sci III. 2001 Mar; 324(3):251-60.
    View in: PubMed
    Score: 0.045
  37. Sartorius CA, Lu BD, Acakpo-Satchivi L, Jacobsen RP, Byrnes WC, Leinwand LA. Myosin heavy chains IIa and IId are functionally distinct in the mouse. J Cell Biol. 1998 May 18; 141(4):943-53.
    View in: PubMed
    Score: 0.037
  38. Nakao K, Minobe W, Roden R, Bristow MR, Leinwand LA. Myosin heavy chain gene expression in human heart failure. J Clin Invest. 1997 Nov 01; 100(9):2362-70.
    View in: PubMed
    Score: 0.035
  39. Kass-Eisler A, Li K, Leinwand LA. Prospects for gene therapy with direct injection of polynucleotides. Ann N Y Acad Sci. 1995 Nov 27; 772:232-40.
    View in: PubMed
    Score: 0.031
  40. Liao L, Sindhwani R, Rojkind M, Factor S, Leinwand L, Diamond B. Antibody-mediated autoimmune myocarditis depends on genetically determined target organ sensitivity. J Exp Med. 1995 Mar 01; 181(3):1123-31.
    View in: PubMed
    Score: 0.029
  41. Smerdu V, Karsch-Mizrachi I, Campione M, Leinwand L, Schiaffino S. Type IIx myosin heavy chain transcripts are expressed in type IIb fibers of human skeletal muscle. Am J Physiol. 1994 Dec; 267(6 Pt 1):C1723-8.
    View in: PubMed
    Score: 0.029
  42. Cho M, Hughes SM, Karsch-Mizrachi I, Travis M, Leinwand LA, Blau HM. Fast myosin heavy chains expressed in secondary mammalian muscle fibers at the time of their inception. J Cell Sci. 1994 Sep; 107 ( Pt 9):2361-71.
    View in: PubMed
    Score: 0.028
  43. Sweeney HL, Straceski AJ, Leinwand LA, Tikunov BA, Faust L. Heterologous expression of a cardiomyopathic myosin that is defective in its actin interaction. J Biol Chem. 1994 Jan 21; 269(3):1603-5.
    View in: PubMed
    Score: 0.027
  44. Liao L, Sindhwani R, Leinwand L, Diamond B, Factor S. Cardiac alpha-myosin heavy chains differ in their induction of myocarditis. Identification of pathogenic epitopes. J Clin Invest. 1993 Dec; 92(6):2877-82.
    View in: PubMed
    Score: 0.027
  45. Hughes SM, Cho M, Karsch-Mizrachi I, Travis M, Silberstein L, Leinwand LA, Blau HM. Three slow myosin heavy chains sequentially expressed in developing mammalian skeletal muscle. Dev Biol. 1993 Jul; 158(1):183-99.
    View in: PubMed
    Score: 0.026
  46. Ogata I, S?ez CG, Greenwel P, Ponce Mde L, Geerts A, Leinwand LA, Rojkind M. Rat liver fat-storing cell lines express sarcomeric myosin heavy chain mRNA and protein. Cell Motil Cytoskeleton. 1993; 26(2):125-32.
    View in: PubMed
    Score: 0.025
  47. Buttrick PM, Kass A, Kitsis RN, Kaplan ML, Leinwand LA. Behavior of genes directly injected into the rat heart in vivo. Circ Res. 1992 Jan; 70(1):193-8.
    View in: PubMed
    Score: 0.024
  48. Feghali R, Karsch-Mizrachi I, Leinwand LA, Kohtz DS. Four sarcomeric myosin heavy chain genes are expressed by human fetal skeletal muscle cells differentiating in culture. Gene Expr. 1992; 2(1):49-58.
    View in: PubMed
    Score: 0.024
  49. Kitsis RN, Buttrick PM, McNally EM, Kaplan ML, Leinwand LA. Hormonal modulation of a gene injected into rat heart in vivo. Proc Natl Acad Sci U S A. 1991 May 15; 88(10):4138-42.
    View in: PubMed
    Score: 0.023
  50. Fishman GI, Hertzberg EL, Spray DC, Leinwand LA. Expression of connexin43 in the developing rat heart. Circ Res. 1991 Mar; 68(3):782-7.
    View in: PubMed
    Score: 0.022
  51. Buttrick P, Malhotra A, Factor S, Greenen D, Leinwand L, Scheuer J. Effect of aging and hypertension on myosin biochemistry and gene expression in the rat heart. Circ Res. 1991 Mar; 68(3):645-52.
    View in: PubMed
    Score: 0.022
  52. Goodwin EB, Leinwand LA, Szent-Gy?rgyi AG. Regulation of scallop myosin by mutant regulatory light chains. J Mol Biol. 1990 Nov 05; 216(1):85-93.
    View in: PubMed
    Score: 0.022
  53. Frankel S, Condeelis J, Leinwand L. Expression of actin in Escherichia coli. Aggregation, solubilization, and functional analysis. J Biol Chem. 1990 Oct 15; 265(29):17980-7.
    View in: PubMed
    Score: 0.022
  54. Leinwand LA, Sohn R, Frankel SA, Goodwin EB, McNally EM. Bacterial expression of eukaryotic contractile proteins. Cell Motil Cytoskeleton. 1989; 14(1):3-11.
    View in: PubMed
    Score: 0.019
  55. De Lozanne A, Berlot CH, Leinwand LA, Spudich JA. Expression in Escherichia coli of a functional Dictyostelium myosin tail fragment. J Cell Biol. 1987 Dec; 105(6 Pt 2):2999-3005.
    View in: PubMed
    Score: 0.018
  56. Warrick HM, De Lozanne A, Leinwand LA, Spudich JA. Conserved protein domains in a myosin heavy chain gene from Dictyostelium discoideum. Proc Natl Acad Sci U S A. 1986 Dec; 83(24):9433-7.
    View in: PubMed
    Score: 0.017
  57. Schwartz CE, McNally E, Leinwand L, Skolnick MH. A polymorphic human myosin heavy chain locus is linked to an anonymous single copy locus (D17S1) at 17p13. Cytogenet Cell Genet. 1986; 43(1-2):117-20.
    View in: PubMed
    Score: 0.016
  58. Kaplan ML, Cheslow Y, Vikstrom K, Malhotra A, Geenen DL, Nakouzi A, Leinwand LA, Buttrick PM. Cardiac adaptations to chronic exercise in mice. Am J Physiol. 1994 Sep; 267(3 Pt 2):H1167-73.
    View in: PubMed
    Score: 0.007
Connection Strength

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