 Connection
Co-Authors
This is a "connection" page, showing publications co-authored by Thomas Cech and Arthur Zaug.
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Connection Strength |
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5.951 |
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Zaug AJ, Goodrich KJ, Song JJ, Sullivan AE, Cech TR. Reconstitution of a telomeric replicon organized by CST. Nature. 2022 08; 608(7924):819-825.
Score: 0.849
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Zaug AJ, Lim CJ, Olson CL, Carilli MT, Goodrich KJ, Wuttke DS, Cech TR. CST does not evict elongating telomerase but prevents initiation by ssDNA binding. Nucleic Acids Res. 2021 11 18; 49(20):11653-11665.
Score: 0.812
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Zaug AJ, Crary SM, Jesse Fioravanti M, Campbell K, Cech TR. Many disease-associated variants of hTERT retain high telomerase enzymatic activity. Nucleic Acids Res. 2013 Oct; 41(19):8969-78.
Score: 0.457
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Zaug AJ, Podell ER, Nandakumar J, Cech TR. Functional interaction between telomere protein TPP1 and telomerase. Genes Dev. 2010 Mar 15; 24(6):613-22.
Score: 0.361
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Zaug AJ, Podell ER, Cech TR. Mutation in TERT separates processivity from anchor-site function. Nat Struct Mol Biol. 2008 Aug; 15(8):870-2.
Score: 0.322
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Zaug AJ, Podell ER, Cech TR. Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro. Proc Natl Acad Sci U S A. 2005 Aug 02; 102(31):10864-9.
Score: 0.262
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Lim CJ, Barbour AT, Zaug AJ, Goodrich KJ, McKay AE, Wuttke DS, Cech TR. The structure of human CST reveals a decameric assembly bound to telomeric DNA. Science. 2020 06 05; 368(6495):1081-1085.
Score: 0.184
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Schmidt JC, Zaug AJ, Kufer R, Cech TR. Dynamics of human telomerase recruitment depend on template-telomere base pairing. Mol Biol Cell. 2018 Apr 01; 29(7):869-880.
Score: 0.158
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Lim CJ, Zaug AJ, Kim HJ, Cech TR. Reconstitution of human shelterin complexes reveals unexpected stoichiometry and dual pathways to enhance telomerase processivity. Nat Commun. 2017 10 20; 8(1):1075.
Score: 0.153
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Schmidt JC, Zaug AJ, Cech TR. Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres. Cell. 2016 Aug 25; 166(5):1188-1197.e9.
Score: 0.141
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Zaug AJ, Linger J, Cech TR. Method for determining RNA 3' ends and application to human telomerase RNA. Nucleic Acids Res. 1996 Feb 01; 24(3):532-3.
Score: 0.136
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Xi L, Schmidt JC, Zaug AJ, Ascarrunz DR, Cech TR. A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression. Genome Biol. 2015 Nov 10; 16:231.
Score: 0.134
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Zaug AJ, Cech TR. Analysis of the structure of Tetrahymena nuclear RNAs in vivo: telomerase RNA, the self-splicing rRNA intron, and U2 snRNA. RNA. 1995 Jun; 1(4):363-74.
Score: 0.130
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Borah S, Xi L, Zaug AJ, Powell NM, Dancik GM, Cohen SB, Costello JC, Theodorescu D, Cech TR. Cancer. TERT promoter mutations and telomerase reactivation in urothelial cancer. Science. 2015 Feb 27; 347(6225):1006-10.
Score: 0.127
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Zaug AJ, D?vila-Aponte JA, Cech TR. Catalysis of RNA cleavage by a ribozyme derived from the group I intron of Anabaena pre-tRNA(Leu). Biochemistry. 1994 Dec 13; 33(49):14935-47.
Score: 0.126
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Zaug AJ, McEvoy MM, Cech TR. Self-splicing of the group I intron from Anabaena pre-tRNA: requirement for base-pairing of the exons in the anticodon stem. Biochemistry. 1993 Aug 10; 32(31):7946-53.
Score: 0.114
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Nandakumar J, Bell CF, Weidenfeld I, Zaug AJ, Leinwand LA, Cech TR. The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity. Nature. 2012 Dec 13; 492(7428):285-9.
Score: 0.108
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Zaug AJ, Cech TR. The intervening sequence RNA of Tetrahymena is an enzyme. 1986. Biotechnology. 1992; 24:57-62.
Score: 0.102
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Zaug AJ, Grosshans CA, Cech TR. Sequence-specific endoribonuclease activity of the Tetrahymena ribozyme: enhanced cleavage of certain oligonucleotide substrates that form mismatched ribozyme-substrate complexes. Biochemistry. 1988 Dec 13; 27(25):8924-31.
Score: 0.083
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Zaug AJ, Cech TR. Self-splicing RNA and an RNA enzyme in Tetrahymena. J Protozool. 1987 Nov; 34(4):416-7.
Score: 0.077
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Zaug AJ, Been MD, Cech TR. The Tetrahymena ribozyme acts like an RNA restriction endonuclease. Nature. 1986 Dec 4-10; 324(6096):429-33.
Score: 0.072
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Zaug AJ, Cech TR. The Tetrahymena intervening sequence ribonucleic acid enzyme is a phosphotransferase and an acid phosphatase. Biochemistry. 1986 Aug 12; 25(16):4478-82.
Score: 0.070
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Zaug AJ, Cech TR. The intervening sequence RNA of Tetrahymena is an enzyme. Science. 1986 Jan 31; 231(4737):470-5.
Score: 0.068
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Zaug AJ, Kent JR, Cech TR. Reactions of the intervening sequence of the Tetrahymena ribosomal ribonucleic acid precursor: pH dependence of cyclization and site-specific hydrolysis. Biochemistry. 1985 Oct 22; 24(22):6211-8.
Score: 0.067
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Zaug AJ, Cech TR. Oligomerization of intervening sequence RNA molecules in the absence of proteins. Science. 1985 Sep 13; 229(4718):1060-4.
Score: 0.066
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Lei M, Zaug AJ, Podell ER, Cech TR. Switching human telomerase on and off with hPOT1 protein in vitro. J Biol Chem. 2005 May 27; 280(21):20449-56.
Score: 0.064
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Forino NM, Woo JZ, Zaug AJ, Jimenez AG, Edelson E, Cech TR, Rouskin S, Stone MD. Telomerase RNA structural heterogeneity in living human cells detected by DMS-MaPseq. bioRxiv. 2024 Aug 29.
Score: 0.062
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Zaug AJ, Kent JR, Cech TR. A labile phosphodiester bond at the ligation junction in a circular intervening sequence RNA. Science. 1984 May 11; 224(4649):574-8.
Score: 0.060
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Seto AG, Umansky K, Tzfati Y, Zaug AJ, Blackburn EH, Cech TR. A template-proximal RNA paired element contributes to Saccharomyces cerevisiae telomerase activity. RNA. 2003 Nov; 9(11):1323-32.
Score: 0.058
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Zaug AJ, Grabowski PJ, Cech TR. Autocatalytic cyclization of an excised intervening sequence RNA is a cleavage-ligation reaction. Nature. 1983 Feb 17-23; 301(5901):578-83.
Score: 0.055
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Zaug AJ, Cech TR. The intervening sequence excised from the ribosomal RNA precursor of Tetrahymena contains a 5-terminal guanosine residue not encoded by the DNA. Nucleic Acids Res. 1982 May 11; 10(9):2823-38.
Score: 0.052
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Livengood AJ, Zaug AJ, Cech TR. Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction. Mol Cell Biol. 2002 Apr; 22(7):2366-74.
Score: 0.052
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Zaug AJ, Cech TR. In vitro splicing of the ribosomal RNA precursor in nuclei of Tetrahymena. Cell. 1980 Feb; 19(2):331-8.
Score: 0.045
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Seto AG, Zaug AJ, Sobel SG, Wolin SL, Cech TR. Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle. Nature. 1999 Sep 09; 401(6749):177-80.
Score: 0.044
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Chapon C, Cech TR, Zaug AJ. Polyadenylation of telomerase RNA in budding yeast. RNA. 1997 Nov; 3(11):1337-51.
Score: 0.038
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Nakamura TM, Wang YH, Zaug AJ, Griffith JD, Cech TR. Relative orientation of RNA helices in a group 1 ribozyme determined by helix extension electron microscopy. EMBO J. 1995 Oct 02; 14(19):4849-59.
Score: 0.033
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Tang M, Li Y, Zhang Y, Chen Y, Huang W, Wang D, Zaug AJ, Liu D, Zhao Y, Cech TR, Ma W, Songyang Z. Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance. J Cell Sci. 2015 Jan 15; 128(2):331-41.
Score: 0.031
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Piccirilli JA, McConnell TS, Zaug AJ, Noller HF, Cech TR. Aminoacyl esterase activity of the Tetrahymena ribozyme. Science. 1992 Jun 05; 256(5062):1420-4.
Score: 0.026
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Batista LF, Pech MF, Zhong FL, Nguyen HN, Xie KT, Zaug AJ, Crary SM, Choi J, Sebastiano V, Cherry A, Giri N, Wernig M, Alter BP, Cech TR, Savage SA, Reijo Pera RA, Artandi SE. Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells. Nature. 2011 May 22; 474(7351):399-402.
Score: 0.025
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Latham JA, Zaug AJ, Cech TR. Self-splicing and enzymatic cleavage of RNA by a group I intervening sequence. Methods Enzymol. 1990; 181:558-69.
Score: 0.022
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Wang F, Podell ER, Zaug AJ, Yang Y, Baciu P, Cech TR, Lei M. The POT1-TPP1 telomere complex is a telomerase processivity factor. Nature. 2007 Feb 01; 445(7127):506-10.
Score: 0.018
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Been MD, Barfod ET, Burke JM, Price JV, Tanner NK, Zaug AJ, Cech TR. Structures involved in Tetrahymena rRNA self-splicing and RNA enzyme activity. Cold Spring Harb Symp Quant Biol. 1987; 52:147-57.
Score: 0.018
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Burke JM, Irvine KD, Kaneko KJ, Kerker BJ, Oettgen AB, Tierney WM, Williamson CL, Zaug AJ, Cech TR. Role of conserved sequence elements 9L and 2 in self-splicing of the Tetrahymena ribosomal RNA precursor. Cell. 1986 Apr 25; 45(2):167-76.
Score: 0.017
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F?rstemann K, Zaug AJ, Cech TR, Lingner J. Yeast telomerase is specialized for C/A-rich RNA templates. Nucleic Acids Res. 2003 Mar 15; 31(6):1646-55.
Score: 0.014
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Kruger K, Grabowski PJ, Zaug AJ, Sands J, Gottschling DE, Cech TR. Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena. Cell. 1982 Nov; 31(1):147-57.
Score: 0.014
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Cech TR, Zaug AJ, Grabowski PJ. In vitro splicing of the ribosomal RNA precursor of Tetrahymena: involvement of a guanosine nucleotide in the excision of the intervening sequence. Cell. 1981 Dec; 27(3 Pt 2):487-96.
Score: 0.013
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Grabowski PJ, Zaug AJ, Cech TR. The intervening sequence of the ribosomal RNA precursor is converted to a circular RNA in isolated nuclei of Tetrahymena. Cell. 1981 Feb; 23(2):467-76.
Score: 0.012
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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