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Connection

Thomas Cech to Oligoribonucleotides

This is a "connection" page, showing publications Thomas Cech has written about Oligoribonucleotides.

 
Connection Strength
 
 
 
0.816
 
  1. Strobel SA, Cech TR. Minor groove recognition of the conserved G.U pair at the Tetrahymena ribozyme reaction site. Science. 1995 Feb 03; 267(5198):675-9.
    View in: PubMed
    Score: 0.123
  2. Herschlag D, Piccirilli JA, Cech TR. Ribozyme-catalyzed and nonenzymatic reactions of phosphate diesters: rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom. Biochemistry. 1991 May 21; 30(20):4844-54.
    View in: PubMed
    Score: 0.095
  3. Herschlag D, Cech TR. Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 2. Kinetic description of the reaction of an RNA substrate that forms a mismatch at the active site. Biochemistry. 1990 Nov 06; 29(44):10172-80.
    View in: PubMed
    Score: 0.092
  4. Celander DW, Cech TR. Iron(II)-ethylenediaminetetraacetic acid catalyzed cleavage of RNA and DNA oligonucleotides: similar reactivity toward single- and double-stranded forms. Biochemistry. 1990 Feb 13; 29(6):1355-61.
    View in: PubMed
    Score: 0.087
  5. Zaug AJ, Grosshans CA, Cech TR. Sequence-specific endoribonuclease activity of the Tetrahymena ribozyme: enhanced cleavage of certain oligonucleotide substrates that form mismatched ribozyme-substrate complexes. Biochemistry. 1988 Dec 13; 27(25):8924-31.
    View in: PubMed
    Score: 0.080
  6. Cohen SB, Cech TR. A quantitative study of the flexibility contributed to RNA structures by nicks and single-stranded gaps. RNA. 1998 Oct; 4(10):1179-85.
    View in: PubMed
    Score: 0.040
  7. McConnell TS, Herschlag D, Cech TR. Effects of divalent metal ions on individual steps of the Tetrahymena ribozyme reaction. Biochemistry. 1997 Jul 08; 36(27):8293-303.
    View in: PubMed
    Score: 0.036
  8. Campbell TB, Cech TR. Mutations in the Tetrahymena ribozyme internal guide sequence: effects on docking of the P1 helix into the catalytic core and correlation with catalytic activity. Biochemistry. 1996 Sep 03; 35(35):11493-502.
    View in: PubMed
    Score: 0.034
  9. Nakamura TM, Wang YH, Zaug AJ, Griffith JD, Cech TR. Relative orientation of RNA helices in a group 1 ribozyme determined by helix extension electron microscopy. EMBO J. 1995 Oct 02; 14(19):4849-59.
    View in: PubMed
    Score: 0.032
  10. Wang JF, Downs WD, Cech TR. Movement of the guide sequence during RNA catalysis by a group I ribozyme. Science. 1993 Apr 23; 260(5107):504-8.
    View in: PubMed
    Score: 0.027
  11. Legault P, Herschlag D, Celander DW, Cech TR. Mutations at the guanosine-binding site of the Tetrahymena ribozyme also affect site-specific hydrolysis. Nucleic Acids Res. 1992 Dec 25; 20(24):6613-9.
    View in: PubMed
    Score: 0.027
  12. Piccirilli JA, McConnell TS, Zaug AJ, Noller HF, Cech TR. Aminoacyl esterase activity of the Tetrahymena ribozyme. Science. 1992 Jun 05; 256(5062):1420-4.
    View in: PubMed
    Score: 0.026
  13. Pyle AM, Cech TR. Ribozyme recognition of RNA by tertiary interactions with specific ribose 2'-OH groups. Nature. 1991 Apr 18; 350(6319):628-31.
    View in: PubMed
    Score: 0.024
  14. Herschlag D, Cech TR. Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site. Biochemistry. 1990 Nov 06; 29(44):10159-71.
    View in: PubMed
    Score: 0.023
  15. Grosshans CA, Cech TR. Metal ion requirements for sequence-specific endoribonuclease activity of the Tetrahymena ribozyme. Biochemistry. 1989 Aug 22; 28(17):6888-94.
    View in: PubMed
    Score: 0.021
  16. Sullivan FX, Cech TR. Reversibility of cyclization of the Tetrahymena rRNA intervening sequence: implication for the mechanism of splice site choice. Cell. 1985 Sep; 42(2):639-48.
    View in: PubMed
    Score: 0.016
  17. Zaug AJ, Grabowski PJ, Cech TR. Autocatalytic cyclization of an excised intervening sequence RNA is a cleavage-ligation reaction. Nature. 1983 Feb 17-23; 301(5901):578-83.
    View in: PubMed
    Score: 0.013
  18. Zaug AJ, Cech TR. The intervening sequence excised from the ribosomal RNA precursor of Tetrahymena contains a 5-terminal guanosine residue not encoded by the DNA. Nucleic Acids Res. 1982 May 11; 10(9):2823-38.
    View in: PubMed
    Score: 0.013
  19. Doudna JA, Cech TR, Sullenger BA. Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor. Proc Natl Acad Sci U S A. 1995 Mar 14; 92(6):2355-9.
    View in: PubMed
    Score: 0.008
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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