 Connection
Thomas Cech to DNA
This is a "connection" page, showing publications Thomas Cech has written about DNA.
|
|
| |
Connection Strength |
|
 |
|
 |
| |
3.422 |
|
|
|
-
Hemphill WO, Steiner HR, Kominsky JR, Wuttke DS, Cech TR. Transcription factors ERa and Sox2 have differing multiphasic DNA- and RNA-binding mechanisms. RNA. 2024 07 16; 30(8):1089-1105.
Score: 0.563
-
Dalby AB, Hofr C, Cech TR. Contributions of the TEL-patch amino acid cluster on TPP1 to telomeric DNA synthesis by human telomerase. J Mol Biol. 2015 Mar 27; 427(6 Pt B):1291-1303.
Score: 0.292
-
Nandakumar J, Podell ER, Cech TR. How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA. Proc Natl Acad Sci U S A. 2010 Jan 12; 107(2):651-6.
Score: 0.205
-
Vicens Q, Cech TR. Atomic level architecture of group I introns revealed. Trends Biochem Sci. 2006 Jan; 31(1):41-51.
Score: 0.155
-
Johnson K, Seidel JM, Cech TR. Small molecule telomerase inhibitors are also potent inhibitors of telomeric C-strand synthesis. RNA. 2024 08 16; 30(9):1213-1226.
Score: 0.142
-
Hemphill WO, Voong CK, Fenske R, Goodrich JA, Cech TR. Multiple RNA- and DNA-binding proteins exhibit direct transfer of polynucleotides with implications for target-site search. Proc Natl Acad Sci U S A. 2023 06 27; 120(26):e2220537120.
Score: 0.131
-
Hemphill WO, Fenske R, Gooding AR, Cech TR. PRC2 direct transfer from G-quadruplex RNA to dsDNA has implications for RNA-binding chromatin modifiers. Proc Natl Acad Sci U S A. 2023 06 06; 120(23):e2220528120.
Score: 0.130
-
Jansson-Fritzberg LI, Sousa CI, Smallegan MJ, Song JJ, Gooding AR, Kasinath V, Rinn JL, Cech TR. DNMT1 inhibition by pUG-fold quadruplex RNA. RNA. 2023 03; 29(3):346-360.
Score: 0.126
-
Lim CJ, Cech TR. Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization. Nat Rev Mol Cell Biol. 2021 04; 22(4):283-298.
Score: 0.111
-
Heenan PR, Wang X, Gooding AR, Cech TR, Perkins TT. Bending and looping of long DNA by Polycomb repressive complex 2 revealed by AFM imaging in liquid. Nucleic Acids Res. 2020 04 06; 48(6):2969-2981.
Score: 0.105
-
Stern JL, Paucek RD, Huang FW, Ghandi M, Nwumeh R, Costello JC, Cech TR. Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes. Cell Rep. 2017 12 26; 21(13):3700-3707.
Score: 0.089
-
Wang X, Paucek RD, Gooding AR, Brown ZZ, Ge EJ, Muir TW, Cech TR. Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA. Nat Struct Mol Biol. 2017 Dec; 24(12):1028-1038.
Score: 0.088
-
Hammond PW, Lively TN, Cech TR. The anchor site of telomerase from Euplotes aediculatus revealed by photo-cross-linking to single- and double-stranded DNA primers. Mol Cell Biol. 1997 Jan; 17(1):296-308.
Score: 0.084
-
Wang X, Schwartz JC, Cech TR. Nucleic acid-binding specificity of human FUS protein. Nucleic Acids Res. 2015 Sep 03; 43(15):7535-43.
Score: 0.075
-
Hicke BJ, Willis MC, Koch TH, Cech TR. Telomeric protein-DNA point contacts identified by photo-cross-linking using 5-bromodeoxyuridine. Biochemistry. 1994 Mar 22; 33(11):3364-73.
Score: 0.069
-
Fang G, Cech TR. Characterization of a G-quartet formation reaction promoted by the beta-subunit of the Oxytricha telomere-binding protein. Biochemistry. 1993 Nov 02; 32(43):11646-57.
Score: 0.067
-
Raghuraman MK, Cech TR. Effect of monovalent cation-induced telomeric DNA structure on the binding of Oxytricha telomeric protein. Nucleic Acids Res. 1990 Aug 11; 18(15):4543-52.
Score: 0.054
-
Herschlag D, Cech TR. DNA cleavage catalysed by the ribozyme from Tetrahymena. Nature. 1990 Mar 29; 344(6265):405-9.
Score: 0.052
-
Williamson JR, Raghuraman MK, Cech TR. Monovalent cation-induced structure of telomeric DNA: the G-quartet model. Cell. 1989 Dec 01; 59(5):871-80.
Score: 0.051
-
Zaug AJ, Podell ER, Cech TR. Mutation in TERT separates processivity from anchor-site function. Nat Struct Mol Biol. 2008 Aug; 15(8):870-2.
Score: 0.046
-
Cech TR. G-strings at chromosome ends. Nature. 1988 Apr 28; 332(6167):777-8.
Score: 0.046
-
Price CM, Cech TR. Telomeric DNA-protein interactions of Oxytricha macronuclear DNA. Genes Dev. 1987 Oct; 1(8):783-93.
Score: 0.044
-
Jacobs SA, Podell ER, Cech TR. Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase. Nat Struct Mol Biol. 2006 Mar; 13(3):218-25.
Score: 0.039
-
Zaug AJ, Podell ER, Cech TR. Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro. Proc Natl Acad Sci U S A. 2005 Aug 02; 102(31):10864-9.
Score: 0.038
-
Opresko PL, Mason PA, Podell ER, Lei M, Hickson ID, Cech TR, Bohr VA. POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates. J Biol Chem. 2005 Sep 16; 280(37):32069-80.
Score: 0.038
-
Lei M, Zaug AJ, Podell ER, Cech TR. Switching human telomerase on and off with hPOT1 protein in vitro. J Biol Chem. 2005 May 27; 280(21):20449-56.
Score: 0.037
-
Cech TR. Beginning to understand the end of the chromosome. Cell. 2004 Jan 23; 116(2):273-9.
Score: 0.034
-
Brehm SL, Cech TR. Fate of an intervening sequence ribonucleic acid: excision and cyclization of the Tetrahymena ribosomal ribonucleic acid intervening sequence in vivo. Biochemistry. 1983 May 10; 22(10):2390-7.
Score: 0.032
-
Palen TE, Cech TR. Transcribed and non-transcribed regions of Tetrahymena ribosomal gene chromatin have different accessibilities to micrococcal nuclease. Nucleic Acids Res. 1983 Apr 11; 11(7):2077-91.
Score: 0.032
-
Gottschling DE, Palen TE, Cech TR. Different nucleosome spacing in transcribed and non-transcribed regions of the ribosomal RNA gene in Tetrahymena thermophila. Nucleic Acids Res. 1983 Apr 11; 11(7):2093-109.
Score: 0.032
-
Baumann P, Podell E, Cech TR. Human Pot1 (protection of telomeres) protein: cytolocalization, gene structure, and alternative splicing. Mol Cell Biol. 2002 Nov; 22(22):8079-87.
Score: 0.031
-
Zaug AJ, Cech TR. The intervening sequence excised from the ribosomal RNA precursor of Tetrahymena contains a 5-terminal guanosine residue not encoded by the DNA. Nucleic Acids Res. 1982 May 11; 10(9):2823-38.
Score: 0.030
-
Cech TR, Brehm SL. Replication of the extrachromosomal ribosomal RNA genes of Tetrahymena thermophilia. Nucleic Acids Res. 1981 Jul 24; 9(14):3531-43.
Score: 0.029
-
Baumann P, Cech TR. Pot1, the putative telomere end-binding protein in fission yeast and humans. Science. 2001 May 11; 292(5519):1171-5.
Score: 0.028
-
Cech T, Pathak MA, Biswas RK. An electron microscopic study of the photochemical cross-linking of DNA in guinea pig epidermis by psoralen derivatives. Biochim Biophys Acta. 1979 Apr 26; 562(2):342-60.
Score: 0.025
-
Cech TR, Potter D, Pardue ML. Chromatin structure in living cells. Cold Spring Harb Symp Quant Biol. 1978; 42 Pt 1:191-8.
Score: 0.022
-
Cech T, Potter D, Pardue ML. Electron microscopy of DNA cross-linked with trimethylpsoralen: a probe for chromatin structure. Biochemistry. 1977 Nov 29; 16(24):5313-21.
Score: 0.022
-
Cech T, Pardue ML. Cross-linking of DNA with trimethylpsoralen is a probe for chromatin structure. Cell. 1977 Jul; 11(3):631-40.
Score: 0.022
-
Cech TR, Pardue ML. Electron microscopy of DNA crosslinked with trimethylpsoralen: test of the secondary structure of eukaryotic inverted repeat sequences. Proc Natl Acad Sci U S A. 1976 Aug; 73(8):2644-8.
Score: 0.020
-
Cech TR, Reisler F, Hearst JE. Partial denaturation of mouse DNA in preparative CsCl density gradients at alkaline pH. Biochemistry. 1976 May 04; 15(9):1865-73.
Score: 0.020
-
Cech TR, Hearst JE. Organization of highly repeated sequences in mouse main-band DNA. J Mol Biol. 1976 Jan 25; 100(3):227-56.
Score: 0.020
-
Cech TR, Hearst JE. An electron microscopic study of mouse foldback DNA. Cell. 1975 Aug; 5(4):429-46.
Score: 0.019
-
Cech TR, Rosenfeld A, Hearst JE. Characterization of the most rapidly renaturing sequences in mouse main-band DNA. J Mol Biol. 1973 Dec 15; 81(3):299-325.
Score: 0.017
-
Willis MC, Hicke BJ, Uhlenbeck OC, Cech TR, Koch TH. Photocrosslinking of 5-iodouracil-substituted RNA and DNA to proteins. Science. 1993 Nov 19; 262(5137):1255-7.
Score: 0.017
-
Herschlag D, Eckstein F, Cech TR. Contributions of 2'-hydroxyl groups of the RNA substrate to binding and catalysis by the Tetrahymena ribozyme. An energetic picture of an active site composed of RNA. Biochemistry. 1993 Aug 17; 32(32):8299-311.
Score: 0.017
-
Herschlag D, Eckstein F, Cech TR. The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction. Biochemistry. 1993 Aug 17; 32(32):8312-21.
Score: 0.017
-
Wang JF, Downs WD, Cech TR. Movement of the guide sequence during RNA catalysis by a group I ribozyme. Science. 1993 Apr 23; 260(5107):504-8.
Score: 0.016
-
Hicke BJ, Celander DW, MacDonald GH, Price CM, Cech TR. Two versions of the gene encoding the 41-kilodalton subunit of the telomere binding protein of Oxytricha nova. Proc Natl Acad Sci U S A. 1990 Feb; 87(4):1481-5.
Score: 0.013
-
Raghuraman MK, Cech TR. Assembly and self-association of oxytricha telomeric nucleoprotein complexes. Cell. 1989 Nov 17; 59(4):719-28.
Score: 0.013
-
Cech TR, Karrer KM. Chromatin structure of the ribosomal RNA genes of Tetrahymena thermophila as analyzed by trimethylpsoralen crosslinking in vivo. J Mol Biol. 1980 Feb 05; 136(4):395-416.
Score: 0.006
-
Zaug AJ, Cech TR. In vitro splicing of the ribosomal RNA precursor in nuclei of Tetrahymena. Cell. 1980 Feb; 19(2):331-8.
Score: 0.006
-
Hearst JE, Cech TR, Marx KA, Rosenfeld A, Allen JR. Characterization of the rapidly renaturing sequences in the main CsCl density bands of Drosophila, mouse, and human DNA. Cold Spring Harb Symp Quant Biol. 1974; 38:329-39.
Score: 0.004
|
Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
|