 Connection
Thomas Cech to Guanosine
This is a "connection" page, showing publications Thomas Cech has written about Guanosine.
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Connection Strength |
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1.222 |
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Guo F, Gooding AR, Cech TR. Structure of the Tetrahymena ribozyme: base triple sandwich and metal ion at the active site. Mol Cell. 2004 Nov 05; 16(3):351-62.
Score: 0.231
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Kuo LY, Cech TR. Conserved thermochemistry of guanosine nucleophile binding for structurally distinct group I ribozymes. Nucleic Acids Res. 1996 Oct 01; 24(19):3722-7.
Score: 0.132
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Strobel SA, Cech TR. Exocyclic amine of the conserved G.U pair at the cleavage site of the Tetrahymena ribozyme contributes to 5'-splice site selection and transition state stabilization. Biochemistry. 1996 Jan 30; 35(4):1201-11.
Score: 0.126
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McConnell TS, Cech TR. A positive entropy change for guanosine binding and for the chemical step in the Tetrahymena ribozyme reaction. Biochemistry. 1995 Mar 28; 34(12):4056-67.
Score: 0.119
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Legault P, Herschlag D, Celander DW, Cech TR. Mutations at the guanosine-binding site of the Tetrahymena ribozyme also affect site-specific hydrolysis. Nucleic Acids Res. 1992 Dec 25; 20(24):6613-9.
Score: 0.101
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Wang JF, Cech TR. Tertiary structure around the guanosine-binding site of the Tetrahymena ribozyme. Science. 1992 Apr 24; 256(5056):526-9.
Score: 0.097
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Tanner NK, Cech TR. Guanosine binding required for cyclization of the self-splicing intervening sequence ribonucleic acid from Tetrahymena thermophila. Biochemistry. 1987 Jun 16; 26(12):3330-40.
Score: 0.069
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Bass BL, Cech TR. Specific interaction between the self-splicing RNA of Tetrahymena and its guanosine substrate: implications for biological catalysis by RNA. Nature. 1984 Apr 26-May 2; 308(5962):820-6.
Score: 0.055
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Seto AG, Zaug AJ, Sobel SG, Wolin SL, Cech TR. Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle. Nature. 1999 Sep 09; 401(6749):177-80.
Score: 0.040
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Golden BL, Gooding AR, Podell ER, Cech TR. A preorganized active site in the crystal structure of the Tetrahymena ribozyme. Science. 1998 Oct 09; 282(5387):259-64.
Score: 0.038
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Tanner MA, Cech TR. Joining the two domains of a group I ribozyme to form the catalytic core. Science. 1997 Feb 07; 275(5301):847-9.
Score: 0.034
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Golden BL, Cech TR. Conformational switches involved in orchestrating the successive steps of group I RNA splicing. Biochemistry. 1996 Mar 26; 35(12):3754-63.
Score: 0.032
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McConnell TS, Cech TR, Herschlag D. Guanosine binding to the Tetrahymena ribozyme: thermodynamic coupling with oligonucleotide binding. Proc Natl Acad Sci U S A. 1993 Sep 15; 90(18):8362-6.
Score: 0.027
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Pyle AM, Murphy FL, Cech TR. RNA substrate binding site in the catalytic core of the Tetrahymena ribozyme. Nature. 1992 Jul 09; 358(6382):123-8.
Score: 0.025
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Cech TR. Self-splicing of group I introns. Annu Rev Biochem. 1990; 59:543-68.
Score: 0.021
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Flor PJ, Flanegan JB, Cech TR. A conserved base pair within helix P4 of the Tetrahymena ribozyme helps to form the tertiary structure required for self-splicing. EMBO J. 1989 Nov; 8(11):3391-9.
Score: 0.020
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McSwiggen JA, Cech TR. Stereochemistry of RNA cleavage by the Tetrahymena ribozyme and evidence that the chemical step is not rate-limiting. Science. 1989 May 12; 244(4905):679-83.
Score: 0.020
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Price JV, Cech TR. Determinants of the 3' splice site for self-splicing of the Tetrahymena pre-rRNA. Genes Dev. 1988 Nov; 2(11):1439-47.
Score: 0.019
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Price JV, Engberg J, Cech TR. 5' exon requirement for self-splicing of the Tetrahymena thermophila pre-ribosomal RNA and identification of a cryptic 5' splice site in the 3' exon. J Mol Biol. 1987 Jul 05; 196(1):49-60.
Score: 0.017
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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