 Connection
Thomas Cech to Tetrahymena thermophila
This is a "connection" page, showing publications Thomas Cech has written about Tetrahymena thermophila.
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Connection Strength |
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4.418 |
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Xi L, Cech TR. Protein-RNA interaction restricts telomerase from running through the stop sign. Nat Struct Mol Biol. 2015 Nov; 22(11):835-6.
Score: 0.524
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Berman AJ, Gooding AR, Cech TR. Tetrahymena telomerase protein p65 induces conformational changes throughout telomerase RNA (TER) and rescues telomerase reverse transcriptase and TER assembly mutants. Mol Cell Biol. 2010 Oct; 30(20):4965-76.
Score: 0.365
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Zaug AJ, Podell ER, Cech TR. Mutation in TERT separates processivity from anchor-site function. Nat Struct Mol Biol. 2008 Aug; 15(8):870-2.
Score: 0.316
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Jacobs SA, Podell ER, Cech TR. Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase. Nat Struct Mol Biol. 2006 Mar; 13(3):218-25.
Score: 0.267
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Guo F, Cech TR. In vivo selection of better self-splicing introns in Escherichia coli: the role of the P1 extension helix of the Tetrahymena intron. RNA. 2002 May; 8(5):647-58.
Score: 0.205
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Bryan TM, Goodrich KJ, Cech TR. A mutant of Tetrahymena telomerase reverse transcriptase with increased processivity. J Biol Chem. 2000 Aug 04; 275(31):24199-207.
Score: 0.182
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Golden BL, Gooding AR, Podell ER, Cech TR. A preorganized active site in the crystal structure of the Tetrahymena ribozyme. Science. 1998 Oct 09; 282(5387):259-64.
Score: 0.161
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Bryan TM, Sperger JM, Chapman KB, Cech TR. Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax. Proc Natl Acad Sci U S A. 1998 Jul 21; 95(15):8479-84.
Score: 0.158
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McConnell TS, Herschlag D, Cech TR. Effects of divalent metal ions on individual steps of the Tetrahymena ribozyme reaction. Biochemistry. 1997 Jul 08; 36(27):8293-303.
Score: 0.147
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Rusconi CP, Cech TR. The anticodon is the signal sequence for mitochondrial import of glutamine tRNA in Tetrahymena. Genes Dev. 1996 Nov 15; 10(22):2870-80.
Score: 0.141
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Campbell TB, Cech TR. Mutations in the Tetrahymena ribozyme internal guide sequence: effects on docking of the P1 helix into the catalytic core and correlation with catalytic activity. Biochemistry. 1996 Sep 03; 35(35):11493-502.
Score: 0.139
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Rusconi CP, Cech TR. Mitochondrial import of only one of three nuclear-encoded glutamine tRNAs in Tetrahymena thermophila. EMBO J. 1996 Jul 01; 15(13):3286-95.
Score: 0.137
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Zaug AJ, Cech TR. Analysis of the structure of Tetrahymena nuclear RNAs in vivo: telomerase RNA, the self-splicing rRNA intron, and U2 snRNA. RNA. 1995 Jun; 1(4):363-74.
Score: 0.127
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McConnell TS, Cech TR. A positive entropy change for guanosine binding and for the chemical step in the Tetrahymena ribozyme reaction. Biochemistry. 1995 Mar 28; 34(12):4056-67.
Score: 0.126
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Downs WD, Cech TR. A tertiary interaction in the Tetrahymena intron contributes to selection of the 5' splice site. Genes Dev. 1994 May 15; 8(10):1198-211.
Score: 0.118
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Murphy FL, Cech TR. GAAA tetraloop and conserved bulge stabilize tertiary structure of a group I intron domain. J Mol Biol. 1994 Feb 11; 236(1):49-63.
Score: 0.116
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Strobel SA, Cech TR. Tertiary interactions with the internal guide sequence mediate docking of the P1 helix into the catalytic core of the Tetrahymena ribozyme. Biochemistry. 1993 Dec 14; 32(49):13593-604.
Score: 0.115
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Herschlag D, Eckstein F, Cech TR. Contributions of 2'-hydroxyl groups of the RNA substrate to binding and catalysis by the Tetrahymena ribozyme. An energetic picture of an active site composed of RNA. Biochemistry. 1993 Aug 17; 32(32):8299-311.
Score: 0.112
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Herschlag D, Eckstein F, Cech TR. The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction. Biochemistry. 1993 Aug 17; 32(32):8312-21.
Score: 0.112
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Murphy FL, Cech TR. An independently folding domain of RNA tertiary structure within the Tetrahymena ribozyme. Biochemistry. 1993 May 25; 32(20):5291-300.
Score: 0.111
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Legault P, Herschlag D, Celander DW, Cech TR. Mutations at the guanosine-binding site of the Tetrahymena ribozyme also affect site-specific hydrolysis. Nucleic Acids Res. 1992 Dec 25; 20(24):6613-9.
Score: 0.107
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Pyle AM, Murphy FL, Cech TR. RNA substrate binding site in the catalytic core of the Tetrahymena ribozyme. Nature. 1992 Jul 09; 358(6382):123-8.
Score: 0.104
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Heuer TS, Chandry PS, Belfort M, Celander DW, Cech TR. Folding of group I introns from bacteriophage T4 involves internalization of the catalytic core. Proc Natl Acad Sci U S A. 1991 Dec 15; 88(24):11105-9.
Score: 0.100
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Berman AJ, Akiyama BM, Stone MD, Cech TR. The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis. Nat Struct Mol Biol. 2011 Nov 20; 18(12):1371-5.
Score: 0.100
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Vicens Q, Gooding AR, Laederach A, Cech TR. Local RNA structural changes induced by crystallization are revealed by SHAPE. RNA. 2007 Apr; 13(4):536-48.
Score: 0.072
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Jacobs SA, Podell ER, Wuttke DS, Cech TR. Soluble domains of telomerase reverse transcriptase identified by high-throughput screening. Protein Sci. 2005 Aug; 14(8):2051-8.
Score: 0.064
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Cech TR, Zaug AJ, Grabowski PJ. In vitro splicing of the ribosomal RNA precursor of Tetrahymena: involvement of a guanosine nucleotide in the excision of the intervening sequence. Cell. 1981 Dec; 27(3 Pt 2):487-96.
Score: 0.050
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Weinstein LB, Jones BC, Cosstick R, Cech TR. A second catalytic metal ion in group I ribozyme. Nature. 1997 Aug 21; 388(6644):805-8.
Score: 0.037
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Sullenger BA, Cech TR. Ribozyme-mediated repair of defective mRNA by targeted, trans-splicing. Nature. 1994 Oct 13; 371(6498):619-22.
Score: 0.030
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Wang YH, Murphy FL, Cech TR, Griffith JD. Visualization of a tertiary structural domain of the Tetrahymena group I intron by electron microscopy. J Mol Biol. 1994 Feb 11; 236(1):64-71.
Score: 0.029
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McConnell TS, Cech TR, Herschlag D. Guanosine binding to the Tetrahymena ribozyme: thermodynamic coupling with oligonucleotide binding. Proc Natl Acad Sci U S A. 1993 Sep 15; 90(18):8362-6.
Score: 0.028
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Cate JH, Gooding AR, Podell E, Zhou K, Golden BL, Kundrot CE, Cech TR, Doudna JA. Crystal structure of a group I ribozyme domain: principles of RNA packing. Science. 1996 Sep 20; 273(5282):1678-85.
Score: 0.009
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Cate JH, Gooding AR, Podell E, Zhou K, Golden BL, Szewczak AA, Kundrot CE, Cech TR, Doudna JA. RNA tertiary structure mediation by adenosine platforms. Science. 1996 Sep 20; 273(5282):1696-9.
Score: 0.009
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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