Connection
Thomas Cech to RNA, Protozoan
This is a "connection" page, showing publications Thomas Cech has written about RNA, Protozoan.
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Connection Strength |
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4.578 |
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Berman AJ, Akiyama BM, Stone MD, Cech TR. The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis. Nat Struct Mol Biol. 2011 Nov 20; 18(12):1371-5.
Score: 0.374
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Berman AJ, Gooding AR, Cech TR. Tetrahymena telomerase protein p65 induces conformational changes throughout telomerase RNA (TER) and rescues telomerase reverse transcriptase and TER assembly mutants. Mol Cell Biol. 2010 Oct; 30(20):4965-76.
Score: 0.343
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Vicens Q, Gooding AR, Laederach A, Cech TR. Local RNA structural changes induced by crystallization are revealed by SHAPE. RNA. 2007 Apr; 13(4):536-48.
Score: 0.269
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Guo F, Gooding AR, Cech TR. Comparison of crystal structure interactions and thermodynamics for stabilizing mutations in the Tetrahymena ribozyme. RNA. 2006 Mar; 12(3):387-95.
Score: 0.250
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Bryan TM, Goodrich KJ, Cech TR. Tetrahymena telomerase is active as a monomer. Mol Biol Cell. 2003 Dec; 14(12):4794-804.
Score: 0.212
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Guo F, Cech TR. Evolution of Tetrahymena ribozyme mutants with increased structural stability. Nat Struct Biol. 2002 Nov; 9(11):855-61.
Score: 0.200
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Sperger JM, Cech TR. A stem-loop of Tetrahymena telomerase RNA distant from the template potentiates RNA folding and telomerase activity. Biochemistry. 2001 Jun 19; 40(24):7005-16.
Score: 0.182
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Silverman SK, Cech TR. An early transition state for folding of the P4-P6 RNA domain. RNA. 2001 Feb; 7(2):161-6.
Score: 0.177
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Silverman SK, Deras ML, Woodson SA, Scaringe SA, Cech TR. Multiple folding pathways for the P4-P6 RNA domain. Biochemistry. 2000 Oct 10; 39(40):12465-75.
Score: 0.173
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Hagen M, Cech TR. Self-splicing of the Tetrahymena intron from mRNA in mammalian cells. EMBO J. 1999 Nov 15; 18(22):6491-500.
Score: 0.163
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Silverman SK, Cech TR. RNA tertiary folding monitored by fluorescence of covalently attached pyrene. Biochemistry. 1999 Oct 26; 38(43):14224-37.
Score: 0.162
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Silverman SK, Cech TR. Energetics and cooperativity of tertiary hydrogen bonds in RNA structure. Biochemistry. 1999 Jul 06; 38(27):8691-702.
Score: 0.159
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Szewczak AA, Podell ER, Bevilacqua PC, Cech TR. Thermodynamic stability of the P4-P6 domain RNA tertiary structure measured by temperature gradient gel electrophoresis. Biochemistry. 1998 Aug 11; 37(32):11162-70.
Score: 0.149
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Campbell TB, Cech TR. Identification of ribozymes within a ribozyme library that efficiently cleave a long substrate RNA. RNA. 1995 Aug; 1(6):598-609.
Score: 0.121
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Fang G, Cech TR. Telomerase RNA localized in the replication band and spherical subnuclear organelles in hypotrichous ciliates. J Cell Biol. 1995 Jul; 130(2):243-53.
Score: 0.120
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Zaug AJ, Cech TR. Analysis of the structure of Tetrahymena nuclear RNAs in vivo: telomerase RNA, the self-splicing rRNA intron, and U2 snRNA. RNA. 1995 Jun; 1(4):363-74.
Score: 0.119
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Doudna JA, Cech TR. Self-assembly of a group I intron active site from its component tertiary structural domains. RNA. 1995 Mar; 1(1):36-45.
Score: 0.117
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Murphy FL, Wang YH, Griffith JD, Cech TR. Coaxially stacked RNA helices in the catalytic center of the Tetrahymena ribozyme. Science. 1994 Sep 16; 265(5179):1709-12.
Score: 0.114
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Lingner J, Hendrick LL, Cech TR. Telomerase RNAs of different ciliates have a common secondary structure and a permuted template. Genes Dev. 1994 Aug 15; 8(16):1984-98.
Score: 0.113
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Laggerbauer B, Murphy FL, Cech TR. Two major tertiary folding transitions of the Tetrahymena catalytic RNA. EMBO J. 1994 Jun 01; 13(11):2669-76.
Score: 0.111
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Downs WD, Cech TR. A tertiary interaction in the Tetrahymena intron contributes to selection of the 5' splice site. Genes Dev. 1994 May 15; 8(10):1198-211.
Score: 0.111
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Guo F, Gooding AR, Cech TR. Structure of the Tetrahymena ribozyme: base triple sandwich and metal ion at the active site. Mol Cell. 2004 Nov 05; 16(3):351-62.
Score: 0.057
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Aigner S, Cech TR. The Euplotes telomerase subunit p43 stimulates enzymatic activity and processivity in vitro. RNA. 2004 Jul; 10(7):1108-18.
Score: 0.056
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Aigner S, Postberg J, Lipps HJ, Cech TR. The Euplotes La motif protein p43 has properties of a telomerase-specific subunit. Biochemistry. 2003 May 20; 42(19):5736-47.
Score: 0.052
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Guo F, Cech TR. In vivo selection of better self-splicing introns in Escherichia coli: the role of the P1 extension helix of the Tetrahymena intron. RNA. 2002 May; 8(5):647-58.
Score: 0.048
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Jarstfer MB, Cech TR. Effects of nucleotide analogues on Euplotes aediculatus telomerase processivity: evidence for product-assisted translocation. Biochemistry. 2002 Jan 08; 41(1):151-61.
Score: 0.047
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Aigner S, Lingner J, Goodrich KJ, Grosshans CA, Shevchenko A, Mann M, Cech TR. Euplotes telomerase contains an La motif protein produced by apparent translational frameshifting. EMBO J. 2000 Nov 15; 19(22):6230-9.
Score: 0.044
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Silverman SK, Zheng M, Wu M, Tinoco I, Cech TR. Quantifying the energetic interplay of RNA tertiary and secondary structure interactions. RNA. 1999 Dec; 5(12):1665-74.
Score: 0.041
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Shoffner GM, Wang R, Podell E, Cech TR, Guo F. In Crystallo Selection to Establish New?RNA?Crystal?Contacts. Structure. 2018 09 04; 26(9):1275-1283.e3.
Score: 0.037
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Jabri E, Aigner S, Cech TR. Kinetic and secondary structure analysis of Naegleria andersoni GIR1, a group I ribozyme whose putative biological function is site-specific hydrolysis. Biochemistry. 1997 Dec 23; 36(51):16345-54.
Score: 0.036
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Lingner J, Hughes TR, Shevchenko A, Mann M, Lundblad V, Cech TR. Reverse transcriptase motifs in the catalytic subunit of telomerase. Science. 1997 Apr 25; 276(5312):561-7.
Score: 0.034
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Tanner MA, Cech TR. Joining the two domains of a group I ribozyme to form the catalytic core. Science. 1997 Feb 07; 275(5301):847-9.
Score: 0.034
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Cech TR, Lingner J. Telomerase and the chromosome end replication problem. Ciba Found Symp. 1997; 211:20-8; discussion 28-34.
Score: 0.033
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Golden BL, Gooding AR, Podell ER, Cech TR. X-ray crystallography of large RNAs: heavy-atom derivatives by RNA engineering. RNA. 1996 Dec; 2(12):1295-305.
Score: 0.033
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Cate JH, Gooding AR, Podell E, Zhou K, Golden BL, Kundrot CE, Cech TR, Doudna JA. Crystal structure of a group I ribozyme domain: principles of RNA packing. Science. 1996 Sep 20; 273(5282):1678-85.
Score: 0.033
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Cate JH, Gooding AR, Podell E, Zhou K, Golden BL, Szewczak AA, Kundrot CE, Cech TR, Doudna JA. RNA tertiary structure mediation by adenosine platforms. Science. 1996 Sep 20; 273(5282):1696-9.
Score: 0.033
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Downs WD, Cech TR. Kinetic pathway for folding of the Tetrahymena ribozyme revealed by three UV-inducible crosslinks. RNA. 1996 Jul; 2(7):718-32.
Score: 0.032
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Nakamura TM, Wang YH, Zaug AJ, Griffith JD, Cech TR. Relative orientation of RNA helices in a group 1 ribozyme determined by helix extension electron microscopy. EMBO J. 1995 Oct 02; 14(19):4849-59.
Score: 0.031
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Zaug AJ, D?vila-Aponte JA, Cech TR. Catalysis of RNA cleavage by a ribozyme derived from the group I intron of Anabaena pre-tRNA(Leu). Biochemistry. 1994 Dec 13; 33(49):14935-47.
Score: 0.029
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Pyle AM, Moran S, Strobel SA, Chapman T, Turner DH, Cech TR. Replacement of the conserved G.U with a G-C pair at the cleavage site of the Tetrahymena ribozyme decreases binding, reactivity, and fidelity. Biochemistry. 1994 Nov 22; 33(46):13856-63.
Score: 0.029
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Sullenger BA, Cech TR. Ribozyme-mediated repair of defective mRNA by targeted, trans-splicing. Nature. 1994 Oct 13; 371(6498):619-22.
Score: 0.029
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Cech TR, Damberger SH, Gutell RR. Representation of the secondary and tertiary structure of group I introns. Nat Struct Biol. 1994 May; 1(5):273-80.
Score: 0.028
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Wang JF, Downs WD, Cech TR. Movement of the guide sequence during RNA catalysis by a group I ribozyme. Science. 1993 Apr 23; 260(5107):504-8.
Score: 0.026
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Grosshans CA, Cech TR. A hammerhead ribozyme allows synthesis of a new form of the Tetrahymena ribozyme homogeneous in length with a 3' end blocked for transesterification. Nucleic Acids Res. 1991 Jul 25; 19(14):3875-80.
Score: 0.023
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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