Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Connection

Thomas Cech to RNA, Protozoan

This is a "connection" page, showing publications Thomas Cech has written about RNA, Protozoan.

 
Connection Strength
 
 
 
4.578
 
  1. Berman AJ, Akiyama BM, Stone MD, Cech TR. The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis. Nat Struct Mol Biol. 2011 Nov 20; 18(12):1371-5.
    View in: PubMed
    Score: 0.374
  2. Berman AJ, Gooding AR, Cech TR. Tetrahymena telomerase protein p65 induces conformational changes throughout telomerase RNA (TER) and rescues telomerase reverse transcriptase and TER assembly mutants. Mol Cell Biol. 2010 Oct; 30(20):4965-76.
    View in: PubMed
    Score: 0.343
  3. Vicens Q, Gooding AR, Laederach A, Cech TR. Local RNA structural changes induced by crystallization are revealed by SHAPE. RNA. 2007 Apr; 13(4):536-48.
    View in: PubMed
    Score: 0.269
  4. Guo F, Gooding AR, Cech TR. Comparison of crystal structure interactions and thermodynamics for stabilizing mutations in the Tetrahymena ribozyme. RNA. 2006 Mar; 12(3):387-95.
    View in: PubMed
    Score: 0.250
  5. Bryan TM, Goodrich KJ, Cech TR. Tetrahymena telomerase is active as a monomer. Mol Biol Cell. 2003 Dec; 14(12):4794-804.
    View in: PubMed
    Score: 0.212
  6. Guo F, Cech TR. Evolution of Tetrahymena ribozyme mutants with increased structural stability. Nat Struct Biol. 2002 Nov; 9(11):855-61.
    View in: PubMed
    Score: 0.200
  7. Sperger JM, Cech TR. A stem-loop of Tetrahymena telomerase RNA distant from the template potentiates RNA folding and telomerase activity. Biochemistry. 2001 Jun 19; 40(24):7005-16.
    View in: PubMed
    Score: 0.182
  8. Silverman SK, Cech TR. An early transition state for folding of the P4-P6 RNA domain. RNA. 2001 Feb; 7(2):161-6.
    View in: PubMed
    Score: 0.177
  9. Silverman SK, Deras ML, Woodson SA, Scaringe SA, Cech TR. Multiple folding pathways for the P4-P6 RNA domain. Biochemistry. 2000 Oct 10; 39(40):12465-75.
    View in: PubMed
    Score: 0.173
  10. Hagen M, Cech TR. Self-splicing of the Tetrahymena intron from mRNA in mammalian cells. EMBO J. 1999 Nov 15; 18(22):6491-500.
    View in: PubMed
    Score: 0.163
  11. Silverman SK, Cech TR. RNA tertiary folding monitored by fluorescence of covalently attached pyrene. Biochemistry. 1999 Oct 26; 38(43):14224-37.
    View in: PubMed
    Score: 0.162
  12. Silverman SK, Cech TR. Energetics and cooperativity of tertiary hydrogen bonds in RNA structure. Biochemistry. 1999 Jul 06; 38(27):8691-702.
    View in: PubMed
    Score: 0.159
  13. Szewczak AA, Podell ER, Bevilacqua PC, Cech TR. Thermodynamic stability of the P4-P6 domain RNA tertiary structure measured by temperature gradient gel electrophoresis. Biochemistry. 1998 Aug 11; 37(32):11162-70.
    View in: PubMed
    Score: 0.149
  14. Campbell TB, Cech TR. Identification of ribozymes within a ribozyme library that efficiently cleave a long substrate RNA. RNA. 1995 Aug; 1(6):598-609.
    View in: PubMed
    Score: 0.121
  15. Fang G, Cech TR. Telomerase RNA localized in the replication band and spherical subnuclear organelles in hypotrichous ciliates. J Cell Biol. 1995 Jul; 130(2):243-53.
    View in: PubMed
    Score: 0.120
  16. Zaug AJ, Cech TR. Analysis of the structure of Tetrahymena nuclear RNAs in vivo: telomerase RNA, the self-splicing rRNA intron, and U2 snRNA. RNA. 1995 Jun; 1(4):363-74.
    View in: PubMed
    Score: 0.119
  17. Doudna JA, Cech TR. Self-assembly of a group I intron active site from its component tertiary structural domains. RNA. 1995 Mar; 1(1):36-45.
    View in: PubMed
    Score: 0.117
  18. Murphy FL, Wang YH, Griffith JD, Cech TR. Coaxially stacked RNA helices in the catalytic center of the Tetrahymena ribozyme. Science. 1994 Sep 16; 265(5179):1709-12.
    View in: PubMed
    Score: 0.114
  19. Lingner J, Hendrick LL, Cech TR. Telomerase RNAs of different ciliates have a common secondary structure and a permuted template. Genes Dev. 1994 Aug 15; 8(16):1984-98.
    View in: PubMed
    Score: 0.113
  20. Laggerbauer B, Murphy FL, Cech TR. Two major tertiary folding transitions of the Tetrahymena catalytic RNA. EMBO J. 1994 Jun 01; 13(11):2669-76.
    View in: PubMed
    Score: 0.111
  21. Downs WD, Cech TR. A tertiary interaction in the Tetrahymena intron contributes to selection of the 5' splice site. Genes Dev. 1994 May 15; 8(10):1198-211.
    View in: PubMed
    Score: 0.111
  22. Guo F, Gooding AR, Cech TR. Structure of the Tetrahymena ribozyme: base triple sandwich and metal ion at the active site. Mol Cell. 2004 Nov 05; 16(3):351-62.
    View in: PubMed
    Score: 0.057
  23. Aigner S, Cech TR. The Euplotes telomerase subunit p43 stimulates enzymatic activity and processivity in vitro. RNA. 2004 Jul; 10(7):1108-18.
    View in: PubMed
    Score: 0.056
  24. Aigner S, Postberg J, Lipps HJ, Cech TR. The Euplotes La motif protein p43 has properties of a telomerase-specific subunit. Biochemistry. 2003 May 20; 42(19):5736-47.
    View in: PubMed
    Score: 0.052
  25. Guo F, Cech TR. In vivo selection of better self-splicing introns in Escherichia coli: the role of the P1 extension helix of the Tetrahymena intron. RNA. 2002 May; 8(5):647-58.
    View in: PubMed
    Score: 0.048
  26. Jarstfer MB, Cech TR. Effects of nucleotide analogues on Euplotes aediculatus telomerase processivity: evidence for product-assisted translocation. Biochemistry. 2002 Jan 08; 41(1):151-61.
    View in: PubMed
    Score: 0.047
  27. Aigner S, Lingner J, Goodrich KJ, Grosshans CA, Shevchenko A, Mann M, Cech TR. Euplotes telomerase contains an La motif protein produced by apparent translational frameshifting. EMBO J. 2000 Nov 15; 19(22):6230-9.
    View in: PubMed
    Score: 0.044
  28. Silverman SK, Zheng M, Wu M, Tinoco I, Cech TR. Quantifying the energetic interplay of RNA tertiary and secondary structure interactions. RNA. 1999 Dec; 5(12):1665-74.
    View in: PubMed
    Score: 0.041
  29. Shoffner GM, Wang R, Podell E, Cech TR, Guo F. In Crystallo Selection to Establish New?RNA?Crystal?Contacts. Structure. 2018 09 04; 26(9):1275-1283.e3.
    View in: PubMed
    Score: 0.037
  30. Jabri E, Aigner S, Cech TR. Kinetic and secondary structure analysis of Naegleria andersoni GIR1, a group I ribozyme whose putative biological function is site-specific hydrolysis. Biochemistry. 1997 Dec 23; 36(51):16345-54.
    View in: PubMed
    Score: 0.036
  31. Lingner J, Hughes TR, Shevchenko A, Mann M, Lundblad V, Cech TR. Reverse transcriptase motifs in the catalytic subunit of telomerase. Science. 1997 Apr 25; 276(5312):561-7.
    View in: PubMed
    Score: 0.034
  32. Tanner MA, Cech TR. Joining the two domains of a group I ribozyme to form the catalytic core. Science. 1997 Feb 07; 275(5301):847-9.
    View in: PubMed
    Score: 0.034
  33. Cech TR, Lingner J. Telomerase and the chromosome end replication problem. Ciba Found Symp. 1997; 211:20-8; discussion 28-34.
    View in: PubMed
    Score: 0.033
  34. Golden BL, Gooding AR, Podell ER, Cech TR. X-ray crystallography of large RNAs: heavy-atom derivatives by RNA engineering. RNA. 1996 Dec; 2(12):1295-305.
    View in: PubMed
    Score: 0.033
  35. Cate JH, Gooding AR, Podell E, Zhou K, Golden BL, Kundrot CE, Cech TR, Doudna JA. Crystal structure of a group I ribozyme domain: principles of RNA packing. Science. 1996 Sep 20; 273(5282):1678-85.
    View in: PubMed
    Score: 0.033
  36. Cate JH, Gooding AR, Podell E, Zhou K, Golden BL, Szewczak AA, Kundrot CE, Cech TR, Doudna JA. RNA tertiary structure mediation by adenosine platforms. Science. 1996 Sep 20; 273(5282):1696-9.
    View in: PubMed
    Score: 0.033
  37. Downs WD, Cech TR. Kinetic pathway for folding of the Tetrahymena ribozyme revealed by three UV-inducible crosslinks. RNA. 1996 Jul; 2(7):718-32.
    View in: PubMed
    Score: 0.032
  38. Nakamura TM, Wang YH, Zaug AJ, Griffith JD, Cech TR. Relative orientation of RNA helices in a group 1 ribozyme determined by helix extension electron microscopy. EMBO J. 1995 Oct 02; 14(19):4849-59.
    View in: PubMed
    Score: 0.031
  39. Zaug AJ, D?vila-Aponte JA, Cech TR. Catalysis of RNA cleavage by a ribozyme derived from the group I intron of Anabaena pre-tRNA(Leu). Biochemistry. 1994 Dec 13; 33(49):14935-47.
    View in: PubMed
    Score: 0.029
  40. Pyle AM, Moran S, Strobel SA, Chapman T, Turner DH, Cech TR. Replacement of the conserved G.U with a G-C pair at the cleavage site of the Tetrahymena ribozyme decreases binding, reactivity, and fidelity. Biochemistry. 1994 Nov 22; 33(46):13856-63.
    View in: PubMed
    Score: 0.029
  41. Sullenger BA, Cech TR. Ribozyme-mediated repair of defective mRNA by targeted, trans-splicing. Nature. 1994 Oct 13; 371(6498):619-22.
    View in: PubMed
    Score: 0.029
  42. Cech TR, Damberger SH, Gutell RR. Representation of the secondary and tertiary structure of group I introns. Nat Struct Biol. 1994 May; 1(5):273-80.
    View in: PubMed
    Score: 0.028
  43. Wang JF, Downs WD, Cech TR. Movement of the guide sequence during RNA catalysis by a group I ribozyme. Science. 1993 Apr 23; 260(5107):504-8.
    View in: PubMed
    Score: 0.026
  44. Grosshans CA, Cech TR. A hammerhead ribozyme allows synthesis of a new form of the Tetrahymena ribozyme homogeneous in length with a 3' end blocked for transesterification. Nucleic Acids Res. 1991 Jul 25; 19(14):3875-80.
    View in: PubMed
    Score: 0.023
Connection Strength

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