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Connection

Thomas Cech to HeLa Cells

This is a "connection" page, showing publications Thomas Cech has written about HeLa Cells.

 
Connection Strength
 
 
 
1.167
 
  1. Wu G, Taylor E, Youmans DT, Arnoult N, Cech TR. Rapid dynamics allow the low-abundance RTEL1 helicase to promote telomere replication. Nucleic Acids Res. 2025 Feb 27; 53(5).
    View in: PubMed
    Score: 0.208
  2. Goldfarb KC, Cech TR. Targeted CRISPR disruption reveals a role for RNase MRP RNA in human preribosomal RNA processing. Genes Dev. 2017 01 01; 31(1):59-71.
    View in: PubMed
    Score: 0.118
  3. Schmidt JC, Zaug AJ, Cech TR. Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres. Cell. 2016 Aug 25; 166(5):1188-1197.e9.
    View in: PubMed
    Score: 0.115
  4. Xi L, Schmidt JC, Zaug AJ, Ascarrunz DR, Cech TR. A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression. Genome Biol. 2015 Nov 10; 16:231.
    View in: PubMed
    Score: 0.109
  5. Schmidt JC, Dalby AB, Cech TR. Identification of human TERT elements necessary for telomerase recruitment to telomeres. Elife. 2014 Oct 01; 3.
    View in: PubMed
    Score: 0.101
  6. Xi L, Cech TR. Inventory of telomerase components in human cells reveals multiple subpopulations of hTR and hTERT. Nucleic Acids Res. 2014 Jul; 42(13):8565-77.
    View in: PubMed
    Score: 0.099
  7. Nakashima M, Nandakumar J, Sullivan KD, Espinosa JM, Cech TR. Inhibition of telomerase recruitment and cancer cell death. J Biol Chem. 2013 Nov 15; 288(46):33171-80.
    View in: PubMed
    Score: 0.094
  8. Schwartz JC, Ebmeier CC, Podell ER, Heimiller J, Taatjes DJ, Cech TR. FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2. Genes Dev. 2012 Dec 15; 26(24):2690-5.
    View in: PubMed
    Score: 0.089
  9. Nandakumar J, Bell CF, Weidenfeld I, Zaug AJ, Leinwand LA, Cech TR. The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity. Nature. 2012 Dec 13; 492(7428):285-9.
    View in: PubMed
    Score: 0.088
  10. Dumbovic G, Braunschweig U, Langner HK, Smallegan M, Biayna J, Hass EP, Jastrzebska K, Blencowe B, Cech TR, Caruthers MH, Rinn JL. Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention. Nat Commun. 2021 06 03; 12(1):3308.
    View in: PubMed
    Score: 0.040
  11. Lu Z, Zhang QC, Lee B, Flynn RA, Smith MA, Robinson JT, Davidovich C, Gooding AR, Goodrich KJ, Mattick JS, Mesirov JP, Cech TR, Chang HY. RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure. Cell. 2016 May 19; 165(5):1267-1279.
    View in: PubMed
    Score: 0.028
  12. Shukla S, Schmidt JC, Goldfarb KC, Cech TR, Parker R. Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects. Nat Struct Mol Biol. 2016 Apr; 23(4):286-92.
    View in: PubMed
    Score: 0.028
  13. Ishikawa F, Matunis MJ, Dreyfuss G, Cech TR. Nuclear proteins that bind the pre-mRNA 3' splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n. Mol Cell Biol. 1993 Jul; 13(7):4301-10.
    View in: PubMed
    Score: 0.023
  14. Opresko PL, Mason PA, Podell ER, Lei M, Hickson ID, Cech TR, Bohr VA. POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates. J Biol Chem. 2005 Sep 16; 280(37):32069-80.
    View in: PubMed
    Score: 0.013
  15. Cech TR. RNA splicing: three themes with variations. Cell. 1983 Oct; 34(3):713-6.
    View in: PubMed
    Score: 0.012
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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