 Connection
Thomas Cech to RNA, Ribosomal
This is a "connection" page, showing publications Thomas Cech has written about RNA, Ribosomal.
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Connection Strength |
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3.623 |
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Zhang B, Cech TR. Peptidyl-transferase ribozymes: trans reactions, structural characterization and ribosomal RNA-like features. Chem Biol. 1998 Oct; 5(10):539-53.
Score: 0.147
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Woodson SA, Cech TR. Alternative secondary structures in the 5' exon affect both forward and reverse self-splicing of the Tetrahymena intervening sequence RNA. Biochemistry. 1991 Feb 26; 30(8):2042-50.
Score: 0.087
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Downs WD, Cech TR. An ultraviolet-inducible adenosine-adenosine cross-link reflects the catalytic structure of the Tetrahymena ribozyme. Biochemistry. 1990 Jun 12; 29(23):5605-13.
Score: 0.083
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Herschlag D, Cech TR. DNA cleavage catalysed by the ribozyme from Tetrahymena. Nature. 1990 Mar 29; 344(6265):405-9.
Score: 0.081
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Cech TR. Self-splicing of group I introns. Annu Rev Biochem. 1990; 59:543-68.
Score: 0.080
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Latham JA, Zaug AJ, Cech TR. Self-splicing and enzymatic cleavage of RNA by a group I intervening sequence. Methods Enzymol. 1990; 181:558-69.
Score: 0.080
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Murphy FL, Cech TR. Alteration of substrate specificity for the endoribonucleolytic cleavage of RNA by the Tetrahymena ribozyme. Proc Natl Acad Sci U S A. 1989 Dec; 86(23):9218-22.
Score: 0.080
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Young B, Cech TR. Specificity for 3',5'-linked substrates in RNA-catalyzed RNA polymerization. J Mol Evol. 1989 Dec; 29(6):480-5.
Score: 0.080
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Flor PJ, Flanegan JB, Cech TR. A conserved base pair within helix P4 of the Tetrahymena ribozyme helps to form the tertiary structure required for self-splicing. EMBO J. 1989 Nov; 8(11):3391-9.
Score: 0.079
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Yarus M, Levine J, Morin GB, Cech TR. A Tetrahymena intron nucleotide connected to the GTP/arginine site. Nucleic Acids Res. 1989 Sep 12; 17(17):6969-81.
Score: 0.078
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Grosshans CA, Cech TR. Metal ion requirements for sequence-specific endoribonuclease activity of the Tetrahymena ribozyme. Biochemistry. 1989 Aug 22; 28(17):6888-94.
Score: 0.078
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Latham JA, Cech TR. Defining the inside and outside of a catalytic RNA molecule. Science. 1989 Jul 21; 245(4915):276-82.
Score: 0.078
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Cech TR. RNA chemistry. Ribozyme self-replication? Nature. 1989 Jun 15; 339(6225):507-8.
Score: 0.077
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McSwiggen JA, Cech TR. Stereochemistry of RNA cleavage by the Tetrahymena ribozyme and evidence that the chemical step is not rate-limiting. Science. 1989 May 12; 244(4905):679-83.
Score: 0.077
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Cech TR. Conserved sequences and structures of group I introns: building an active site for RNA catalysis--a review. Gene. 1988 Dec 20; 73(2):259-71.
Score: 0.075
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Zaug AJ, Grosshans CA, Cech TR. Sequence-specific endoribonuclease activity of the Tetrahymena ribozyme: enhanced cleavage of certain oligonucleotide substrates that form mismatched ribozyme-substrate complexes. Biochemistry. 1988 Dec 13; 27(25):8924-31.
Score: 0.075
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Price JV, Cech TR. Determinants of the 3' splice site for self-splicing of the Tetrahymena pre-rRNA. Genes Dev. 1988 Nov; 2(11):1439-47.
Score: 0.074
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Barfod ET, Cech TR. Deletion of nonconserved helices near the 3' end of the rRNA intron of Tetrahymena thermophila alters self-splicing but not core catalytic activity. Genes Dev. 1988 Jun; 2(6):652-63.
Score: 0.072
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Been MD, Cech TR. RNA as an RNA polymerase: net elongation of an RNA primer catalyzed by the Tetrahymena ribozyme. Science. 1988 Mar 18; 239(4846):1412-6.
Score: 0.071
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Kim SH, Cech TR. Three-dimensional model of the active site of the self-splicing rRNA precursor of Tetrahymena. Proc Natl Acad Sci U S A. 1987 Dec; 84(24):8788-92.
Score: 0.069
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Zaug AJ, Cech TR. Self-splicing RNA and an RNA enzyme in Tetrahymena. J Protozool. 1987 Nov; 34(4):416-7.
Score: 0.069
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Been MD, Cech TR. Selection of circularization sites in a group I IVS RNA requires multiple alignments of an internal template-like sequence. Cell. 1987 Sep 11; 50(6):951-61.
Score: 0.068
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Been MD, Barfod ET, Burke JM, Price JV, Tanner NK, Zaug AJ, Cech TR. Structures involved in Tetrahymena rRNA self-splicing and RNA enzyme activity. Cold Spring Harb Symp Quant Biol. 1987; 52:147-57.
Score: 0.065
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Zaug AJ, Been MD, Cech TR. The Tetrahymena ribozyme acts like an RNA restriction endonuclease. Nature. 1986 Dec 4-10; 324(6096):429-33.
Score: 0.065
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Been MD, Cech TR. One binding site determines sequence specificity of Tetrahymena pre-rRNA self-splicing, trans-splicing, and RNA enzyme activity. Cell. 1986 Oct 24; 47(2):207-16.
Score: 0.064
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Bass BL, Cech TR. Ribozyme inhibitors: deoxyguanosine and dideoxyguanosine are competitive inhibitors of self-splicing of the Tetrahymena ribosomal ribonucleic acid precursor. Biochemistry. 1986 Aug 12; 25(16):4473-7.
Score: 0.063
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Inoue T, Sullivan FX, Cech TR. New reactions of the ribosomal RNA precursor of Tetrahymena and the mechanism of self-splicing. J Mol Biol. 1986 May 05; 189(1):143-65.
Score: 0.062
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Burke JM, Irvine KD, Kaneko KJ, Kerker BJ, Oettgen AB, Tierney WM, Williamson CL, Zaug AJ, Cech TR. Role of conserved sequence elements 9L and 2 in self-splicing of the Tetrahymena ribosomal RNA precursor. Cell. 1986 Apr 25; 45(2):167-76.
Score: 0.062
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Zaug AJ, Cech TR. The intervening sequence RNA of Tetrahymena is an enzyme. Science. 1986 Jan 31; 231(4737):470-5.
Score: 0.061
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Cech TR. Biologic catalysis by RNA. Harvey Lect. 1986-1987; 82:123-44.
Score: 0.061
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Been MD, Cech TR. Sites of circularization of the Tetrahymena rRNA IVS are determined by sequence and influenced by position and secondary structure. Nucleic Acids Res. 1985 Dec 09; 13(23):8389-408.
Score: 0.060
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Inoue T, Sullivan FX, Cech TR. Intermolecular exon ligation of the rRNA precursor of Tetrahymena: oligonucleotides can function as 5' exons. Cell. 1985 Dec; 43(2 Pt 1):431-7.
Score: 0.060
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Zaug AJ, Kent JR, Cech TR. Reactions of the intervening sequence of the Tetrahymena ribosomal ribonucleic acid precursor: pH dependence of cyclization and site-specific hydrolysis. Biochemistry. 1985 Oct 22; 24(22):6211-8.
Score: 0.060
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Sullivan FX, Cech TR. Reversibility of cyclization of the Tetrahymena rRNA intervening sequence: implication for the mechanism of splice site choice. Cell. 1985 Sep; 42(2):639-48.
Score: 0.059
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Price JV, Cech TR. Coupling of Tetrahymena ribosomal RNA splicing to beta-galactosidase expression in Escherichia coli. Science. 1985 May 10; 228(4700):719-22.
Score: 0.058
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Price JV, Kieft GL, Kent JR, Sievers EL, Cech TR. Sequence requirements for self-splicing of the Tetrahymena thermophila pre-ribosomal RNA. Nucleic Acids Res. 1985 Mar 25; 13(6):1871-89.
Score: 0.058
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Inoue T, Cech TR. Secondary structure of the circular form of the Tetrahymena rRNA intervening sequence: a technique for RNA structure analysis using chemical probes and reverse transcriptase. Proc Natl Acad Sci U S A. 1985 Feb; 82(3):648-52.
Score: 0.057
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Cech TR. Self-splicing RNA: implications for evolution. Int Rev Cytol. 1985; 93:3-22.
Score: 0.057
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Palen TE, Cech TR. Chromatin structure at the replication origins and transcription-initiation regions of the ribosomal RNA genes of Tetrahymena. Cell. 1984 Apr; 36(4):933-42.
Score: 0.054
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Bass BL, Cech TR. Specific interaction between the self-splicing RNA of Tetrahymena and its guanosine substrate: implications for biological catalysis by RNA. Nature. 1984 Apr 26-May 2; 308(5962):820-6.
Score: 0.054
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Cech TR, Tanner NK, Tinoco I, Weir BR, Zuker M, Perlman PS. Secondary structure of the Tetrahymena ribosomal RNA intervening sequence: structural homology with fungal mitochondrial intervening sequences. Proc Natl Acad Sci U S A. 1983 Jul; 80(13):3903-7.
Score: 0.051
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Brehm SL, Cech TR. Fate of an intervening sequence ribonucleic acid: excision and cyclization of the Tetrahymena ribosomal ribonucleic acid intervening sequence in vivo. Biochemistry. 1983 May 10; 22(10):2390-7.
Score: 0.051
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Palen TE, Cech TR. Transcribed and non-transcribed regions of Tetrahymena ribosomal gene chromatin have different accessibilities to micrococcal nuclease. Nucleic Acids Res. 1983 Apr 11; 11(7):2077-91.
Score: 0.050
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Gottschling DE, Palen TE, Cech TR. Different nucleosome spacing in transcribed and non-transcribed regions of the ribosomal RNA gene in Tetrahymena thermophila. Nucleic Acids Res. 1983 Apr 11; 11(7):2093-109.
Score: 0.050
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Zaug AJ, Grabowski PJ, Cech TR. Autocatalytic cyclization of an excised intervening sequence RNA is a cleavage-ligation reaction. Nature. 1983 Feb 17-23; 301(5901):578-83.
Score: 0.050
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Kruger K, Grabowski PJ, Zaug AJ, Sands J, Gottschling DE, Cech TR. Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena. Cell. 1982 Nov; 31(1):147-57.
Score: 0.049
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Zaug AJ, Cech TR. The intervening sequence excised from the ribosomal RNA precursor of Tetrahymena contains a 5-terminal guanosine residue not encoded by the DNA. Nucleic Acids Res. 1982 May 11; 10(9):2823-38.
Score: 0.047
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Cech TR, Brehm SL. Replication of the extrachromosomal ribosomal RNA genes of Tetrahymena thermophilia. Nucleic Acids Res. 1981 Jul 24; 9(14):3531-43.
Score: 0.045
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Grabowski PJ, Zaug AJ, Cech TR. The intervening sequence of the ribosomal RNA precursor is converted to a circular RNA in isolated nuclei of Tetrahymena. Cell. 1981 Feb; 23(2):467-76.
Score: 0.043
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Cech TR, Karrer KM. Chromatin structure of the ribosomal RNA genes of Tetrahymena thermophila as analyzed by trimethylpsoralen crosslinking in vivo. J Mol Biol. 1980 Feb 05; 136(4):395-416.
Score: 0.040
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Zaug AJ, Cech TR. In vitro splicing of the ribosomal RNA precursor in nuclei of Tetrahymena. Cell. 1980 Feb; 19(2):331-8.
Score: 0.040
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Cech TR, Rio DC. Localization of transcribed regions on extrachromosomal ribosomal RNA genes of Tetrahymena thermophila by R-loop mapping. Proc Natl Acad Sci U S A. 1979 Oct; 76(10):5051-5.
Score: 0.039
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Zaug AJ, Cech TR. Analysis of the structure of Tetrahymena nuclear RNAs in vivo: telomerase RNA, the self-splicing rRNA intron, and U2 snRNA. RNA. 1995 Jun; 1(4):363-74.
Score: 0.029
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Woodson SA, Cech TR. Reverse self-splicing of the tetrahymena group I intron: implication for the directionality of splicing and for intron transposition. Cell. 1989 Apr 21; 57(2):335-45.
Score: 0.019
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Cech TR. RNA as an enzyme. Biochem Int. 1989 Jan; 18(1):7-14.
Score: 0.019
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Morin GB, Cech TR. Phylogenetic relationships and altered genome structures among Tetrahymena mitochondrial DNAs. Nucleic Acids Res. 1988 Jan 11; 16(1):327-46.
Score: 0.017
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Price JV, Engberg J, Cech TR. 5' exon requirement for self-splicing of the Tetrahymena thermophila pre-ribosomal RNA and identification of a cryptic 5' splice site in the 3' exon. J Mol Biol. 1987 Jul 05; 196(1):49-60.
Score: 0.017
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Cech TR. RNA as an enzyme. Sci Am. 1986 Nov; 255(5):64-75.
Score: 0.016
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Garriga G, Lambowitz AM, Inoue T, Cech TR. Mechanism of recognition of the 5' splice site in self-splicing group I introns. Nature. 1986 Jul 3-9; 322(6074):86-9.
Score: 0.016
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Cech TR. A model for the RNA-catalyzed replication of RNA. Proc Natl Acad Sci U S A. 1986 Jun; 83(12):4360-3.
Score: 0.016
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Tanner NK, Cech TR. Self-catalyzed cyclization of the intervening sequence RNA of Tetrahymena: inhibition by methidiumpropyl.EDTA and localization of the major dye binding sites. Nucleic Acids Res. 1985 Nov 11; 13(21):7759-79.
Score: 0.015
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Zaug AJ, Cech TR. Oligomerization of intervening sequence RNA molecules in the absence of proteins. Science. 1985 Sep 13; 229(4718):1060-4.
Score: 0.015
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Gottschling DE, Cech TR. Chromatin structure of the molecular ends of Oxytricha macronuclear DNA: phased nucleosomes and a telomeric complex. Cell. 1984 Sep; 38(2):501-10.
Score: 0.014
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Zaug AJ, Kent JR, Cech TR. A labile phosphodiester bond at the ligation junction in a circular intervening sequence RNA. Science. 1984 May 11; 224(4649):574-8.
Score: 0.014
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Cech TR, Zaug AJ, Grabowski PJ. In vitro splicing of the ribosomal RNA precursor of Tetrahymena: involvement of a guanosine nucleotide in the excision of the intervening sequence. Cell. 1981 Dec; 27(3 Pt 2):487-96.
Score: 0.011
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Cech TR, Pardue ML. Electron microscopy of DNA crosslinked with trimethylpsoralen: test of the secondary structure of eukaryotic inverted repeat sequences. Proc Natl Acad Sci U S A. 1976 Aug; 73(8):2644-8.
Score: 0.008
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Burke JM, Belfort M, Cech TR, Davies RW, Schweyen RJ, Shub DA, Szostak JW, Tabak HF. Structural conventions for group I introns. Nucleic Acids Res. 1987 Sep 25; 15(18):7217-21.
Score: 0.004
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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