 Connection
John Kappler to Lymphocyte Activation
This is a "connection" page, showing publications John Kappler has written about Lymphocyte Activation.
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Connection Strength |
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2.212 |
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Marrack P, Mitchell T, Hildeman D, Kedl R, Teague TK, Bender J, Rees W, Schaefer BC, Kappler J. Genomic-scale analysis of gene expression in resting and activated T cells. Curr Opin Immunol. 2000 Apr; 12(2):206-9.
Score: 0.126
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Marrack P, Mitchell T, Bender J, Hildeman D, Kedl R, Teague K, Kappler J. T-cell survival. Immunol Rev. 1998 Oct; 165:279-85.
Score: 0.113
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Williams T, Krovi HS, Landry LG, Crawford F, Jin N, Hohenstein A, DeNicola ME, Michels AW, Davidson HW, Kent SC, Gapin L, Kappler JW, Nakayama M. Development of T cell lines sensitive to antigen stimulation. J Immunol Methods. 2018 11; 462:65-73.
Score: 0.113
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Noges LE, White J, Cambier JC, Kappler JW, Marrack P. Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines. J Immunol. 2016 08 15; 197(4):1221-30.
Score: 0.097
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David A, Crawford F, Garside P, Kappler JW, Marrack P, MacLeod M. Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation. Proc Natl Acad Sci U S A. 2014 May 27; 111(21):7735-40.
Score: 0.084
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Rubtsova K, Rubtsov AV, van Dyk LF, Kappler JW, Marrack P. T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance. Proc Natl Acad Sci U S A. 2013 Aug 20; 110(34):E3216-24.
Score: 0.079
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Bowerman NA, Falta MT, Mack DG, Kappler JW, Fontenot AP. Mutagenesis of beryllium-specific TCRs suggests an unusual binding topology for antigen recognition. J Immunol. 2011 Oct 01; 187(7):3694-703.
Score: 0.069
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Falta MT, Bowerman NA, Dai S, Kappler JW, Fontenot AP. Linking genetic susceptibility and T cell activation in beryllium-induced disease. Proc Am Thorac Soc. 2010 May; 7(2):126-9.
Score: 0.063
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MacLeod MK, Kappler JW, Marrack P. Memory CD4 T cells: generation, reactivation and re-assignment. Immunology. 2010 May; 130(1):10-5.
Score: 0.063
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Wang Y, Becker D, Vass T, White J, Marrack P, Kappler JW. A conserved CXXC motif in CD3epsilon is critical for T cell development and TCR signaling. PLoS Biol. 2009 Dec; 7(12):e1000253.
Score: 0.061
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Bassetti MF, White J, Kappler JW, Marrack P. Transgenic Bcl-3 slows T cell proliferation. Int Immunol. 2009 Apr; 21(4):339-48.
Score: 0.058
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Yang B, Gay DL, MacLeod MK, Cao X, Hala T, Sweezer EM, Kappler J, Marrack P, Oliver PM. Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells. Nat Immunol. 2008 Dec; 9(12):1356-63.
Score: 0.057
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Dai S, Huseby ES, Rubtsova K, Scott-Browne J, Crawford F, Macdonald WA, Marrack P, Kappler JW. Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules. Immunity. 2008 Mar; 28(3):324-34.
Score: 0.054
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Oliver PM, Cao X, Worthen GS, Shi P, Briones N, MacLeod M, White J, Kirby P, Kappler J, Marrack P, Yang B. Ndfip1 protein promotes the function of itch ubiquitin ligase to prevent T cell activation and T helper 2 cell-mediated inflammation. Immunity. 2006 Dec; 25(6):929-40.
Score: 0.050
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Zhu Y, Liu X, Hildeman D, Peyerl FW, White J, Kushnir E, Kappler J, Marrack P. Bax does not have to adopt its final form to drive T cell death. J Exp Med. 2006 May 15; 203(5):1147-52.
Score: 0.048
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Marrack P, Kappler J. Control of T cell viability. Annu Rev Immunol. 2004; 22:765-87.
Score: 0.041
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Hildeman DA, Mitchell T, Kappler J, Marrack P. T cell apoptosis and reactive oxygen species. J Clin Invest. 2003 Mar; 111(5):575-81.
Score: 0.038
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Hildeman DA, Zhu Y, Mitchell TC, Kappler J, Marrack P. Molecular mechanisms of activated T cell death in vivo. Curr Opin Immunol. 2002 Jun; 14(3):354-9.
Score: 0.037
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Hildeman DA, Zhu Y, Mitchell TC, Bouillet P, Strasser A, Kappler J, Marrack P. Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim. Immunity. 2002 Jun; 16(6):759-67.
Score: 0.037
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Mitchell TC, Hildeman D, Kedl RM, Teague TK, Schaefer BC, White J, Zhu Y, Kappler J, Marrack P. Immunological adjuvants promote activated T cell survival via induction of Bcl-3. Nat Immunol. 2001 May; 2(5):397-402.
Score: 0.034
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Fass? M, Anandasabapathy N, Crawford F, Kappler J, Fathman CG, Ridgway WM. T cell receptor (TCR)-mediated repertoire selection and loss of TCR vbeta diversity during the initiation of a CD4(+) T cell response in vivo. J Exp Med. 2000 Dec 18; 192(12):1719-30.
Score: 0.033
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Gray JI, Al-Khabouri S, Morton F, Clambey ET, Gapin L, Matsuda JL, Kappler JW, Marrack P, Garside P, Otto TD, MacLeod MKL. Tolerance induction in memory CD4 T cells is partial and reversible. Immunology. 2021 01; 162(1):68-83.
Score: 0.033
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Marrack P, Bender J, Hildeman D, Jordan M, Mitchell T, Murakami M, Sakamoto A, Schaefer BC, Swanson B, Kappler J. Homeostasis of alpha beta TCR+ T cells. Nat Immunol. 2000 Aug; 1(2):107-11.
Score: 0.032
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Teague TK, Schaefer BC, Hildeman D, Bender J, Mitchell T, Kappler JW, Marrack P. Activation-induced inhibition of interleukin 6-mediated T cell survival and signal transducer and activator of transcription 1 signaling. J Exp Med. 2000 Mar 20; 191(6):915-26.
Score: 0.031
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Teague TK, Hildeman D, Kedl RM, Mitchell T, Rees W, Schaefer BC, Bender J, Kappler J, Marrack P. Activation changes the spectrum but not the diversity of genes expressed by T cells. Proc Natl Acad Sci U S A. 1999 Oct 26; 96(22):12691-6.
Score: 0.031
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Schaefer BC, Ware MF, Marrack P, Fanger GR, Kappler JW, Johnson GL, Monks CR. Live cell fluorescence imaging of T cell MEKK2: redistribution and activation in response to antigen stimulation of the T cell receptor. Immunity. 1999 Oct; 11(4):411-21.
Score: 0.030
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Hildeman DA, Mitchell T, Teague TK, Henson P, Day BJ, Kappler J, Marrack PC. Reactive oxygen species regulate activation-induced T cell apoptosis. Immunity. 1999 Jun; 10(6):735-44.
Score: 0.030
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Mitchell T, Kappler J, Marrack P. Bystander virus infection prolongs activated T cell survival. J Immunol. 1999 Apr 15; 162(8):4527-35.
Score: 0.029
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Marrack P, Kappler J, Mitchell T. Type I interferons keep activated T cells alive. J Exp Med. 1999 Feb 01; 189(3):521-30.
Score: 0.029
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Crawford F, Kozono H, White J, Marrack P, Kappler J. Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes. Immunity. 1998 Jun; 8(6):675-82.
Score: 0.028
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Vella AT, Dow S, Potter TA, Kappler J, Marrack P. Cytokine-induced survival of activated T cells in vitro and in vivo. Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7):3810-5.
Score: 0.027
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Ignatowicz L, Rees W, Pacholczyk R, Ignatowicz H, Kushnir E, Kappler J, Marrack P. T cells can be activated by peptides that are unrelated in sequence to their selecting peptide. Immunity. 1997 Aug; 7(2):179-86.
Score: 0.026
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Rubtsova K, Rubtsov AV, Thurman JM, Mennona JM, Kappler JW, Marrack P. B cells expressing the transcription factor T-bet drive lupus-like autoimmunity. J Clin Invest. 2017 Apr 03; 127(4):1392-1404.
Score: 0.025
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Hamelmann E, Vella AT, Oshiba A, Kappler JW, Marrack P, Gelfand EW. Allergic airway sensitization induces T cell activation but not airway hyperresponsiveness in B cell-deficient mice. Proc Natl Acad Sci U S A. 1997 Feb 18; 94(4):1350-5.
Score: 0.025
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Araneo BA, Marrack PC, Kappler JW. Functional heterogeneity among the T-derived lymphocytes of the mouse. V. Response kinetics of peripheral T cell subpopulations. J Immunol. 1976 Oct; 117(4):1233-7.
Score: 0.025
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Ignatowicz L, Kappler J, Parker DC, Marrack P. The responses of mature T cells are not necessarily antagonized by their positively selecting peptide. J Immunol. 1996 Sep 01; 157(5):1827-31.
Score: 0.025
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Yang J, Chow IT, Sosinowski T, Torres-Chinn N, Greenbaum CJ, James EA, Kappler JW, Davidson HW, Kwok WW. Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes. Proc Natl Acad Sci U S A. 2014 Oct 14; 111(41):14840-5.
Score: 0.021
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Hugo P, Kappler JW, McCormack JE, Marrack P. Fibroblasts can induce thymocyte positive selection in vivo. Proc Natl Acad Sci U S A. 1993 Nov 01; 90(21):10335-9.
Score: 0.020
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Harris TO, Grossman D, Kappler JW, Marrack P, Rich RR, Betley MJ. Lack of complete correlation between emetic and T-cell-stimulatory activities of staphylococcal enterotoxins. Infect Immun. 1993 Aug; 61(8):3175-83.
Score: 0.020
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Winslow GM, Scherer MT, Kappler JW, Marrack P. Detection and biochemical characterization of the mouse mammary tumor virus 7 superantigen (Mls-1a). Cell. 1992 Nov 27; 71(5):719-30.
Score: 0.019
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MacLeod MK, David A, McKee AS, Crawford F, Kappler JW, Marrack P. Memory CD4 T cells that express CXCR5 provide accelerated help to B cells. J Immunol. 2011 Mar 01; 186(5):2889-96.
Score: 0.017
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Macdonald WA, Chen Z, Gras S, Archbold JK, Tynan FE, Clements CS, Bharadwaj M, Kjer-Nielsen L, Saunders PM, Wilce MC, Crawford F, Stadinsky B, Jackson D, Brooks AG, Purcell AW, Kappler JW, Burrows SR, Rossjohn J, McCluskey J. T cell allorecognition via molecular mimicry. Immunity. 2009 Dec 18; 31(6):897-908.
Score: 0.015
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Kappler J, Kotzin B, Herron L, Gelfand EW, Bigler RD, Boylston A, Carrel S, Posnett DN, Choi Y, Marrack P. V beta-specific stimulation of human T cells by staphylococcal toxins. Science. 1989 May 19; 244(4906):811-3.
Score: 0.015
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MacLeod MK, Clambey ET, Kappler JW, Marrack P. CD4 memory T cells: what are they and what can they do? Semin Immunol. 2009 Apr; 21(2):53-61.
Score: 0.015
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O'Brien RL, Marrack P, Storb U, Kappler JW. B cells expressing Ig transgenes respond to a T-dependent antigen only in the presence of Ia-compatible T cells. J Immunol. 1988 Nov 15; 141(10):3335-41.
Score: 0.014
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MacLeod MK, McKee A, Crawford F, White J, Kappler J, Marrack P. CD4 memory T cells divide poorly in response to antigen because of their cytokine profile. Proc Natl Acad Sci U S A. 2008 Sep 23; 105(38):14521-6.
Score: 0.014
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Gay D, Maddon P, Sekaly R, Talle MA, Godfrey M, Long E, Goldstein G, Chess L, Axel R, Kappler J, et al. Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen. Nature. 1987 Aug 13-19; 328(6131):626-9.
Score: 0.013
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Hildeman D, Jorgensen T, Kappler J, Marrack P. Apoptosis and the homeostatic control of immune responses. Curr Opin Immunol. 2007 Oct; 19(5):516-21.
Score: 0.013
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Liu X, Zhu Y, Dai S, White J, Peyerl F, Kappler JW, Marrack P. Bcl-xl does not have to bind Bax to protect T cells from death. J Exp Med. 2006 Dec 25; 203(13):2953-61.
Score: 0.013
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Willis RA, Kappler JW, Marrack PC. CD8 T cell competition for dendritic cells in vivo is an early event in activation. Proc Natl Acad Sci U S A. 2006 Aug 08; 103(32):12063-8.
Score: 0.012
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Czitrom AA, Edwards S, Phillips RA, Bosma MJ, Marrack P, Kappler JW. The function of antigen-presenting cells in mice with severe combined immunodeficiency. J Immunol. 1985 Apr; 134(4):2276-80.
Score: 0.011
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Jordan MB, Mills DM, Kappler J, Marrack P, Cambier JC. Promotion of B cell immune responses via an alum-induced myeloid cell population. Science. 2004 Jun 18; 304(5678):1808-10.
Score: 0.011
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Leibson HJ, Gefter M, Zlotnik A, Marrack P, Kappler JW. Role of gamma-interferon in antibody-producing responses. Nature. 1984 Jun 28-Jul 4; 309(5971):799-801.
Score: 0.010
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Swain SL, Howard M, Kappler J, Marrack P, Watson J, Booth R, Wetzel GD, Dutton RW. Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays. J Exp Med. 1983 Sep 01; 158(3):822-35.
Score: 0.010
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Daughety TW, Marrack P, Kappler JW, Chiller JM. The capacity of murine alveolar macrophages to stimulate antigen-dependent T-lymphocyte activation and proliferation. Cell Immunol. 1983 Jul 15; 79(2):374-82.
Score: 0.010
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Marrack P, Kappler J. Use of somatic cell genetics to study chromosomes contributing to antigen plus I recognition by T cell hybridomas. J Exp Med. 1983 Feb 01; 157(2):404-18.
Score: 0.010
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Pure E, Isakson PC, Kappler JW, Marrack P, Krammer PH, Vitetta ES. T cell-derived B cell growth and differentiation factors. Dichotomy between the responsiveness of B cells from adult and neonatal mice. J Exp Med. 1983 Feb 01; 157(2):600-12.
Score: 0.010
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Dialynas DP, Wilde DB, Marrack P, Pierres A, Wall KA, Havran W, Otten G, Loken MR, Pierres M, Kappler J, et al. Characterization of the murine antigenic determinant, designated L3T4a, recognized by monoclonal antibody GK1.5: expression of L3T4a by functional T cell clones appears to correlate primarily with class II MHC antigen-reactivity. Immunol Rev. 1983; 74:29-56.
Score: 0.010
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Mitchell TC, Teague TK, Hildeman DA, Bender J, Rees WA, Kedl RM, Swanson B, Kappler JW, Marrack P. Stronger correlation of bcl-3 than bcl-2, bcl-xL, costimulation, or antioxidants with adjuvant-induced T cell survival. Ann N Y Acad Sci. 2002 Dec; 975:114-31.
Score: 0.009
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Swanson BJ, Murakami M, Mitchell TC, Kappler J, Marrack P. RANTES production by memory phenotype T cells is controlled by a posttranscriptional, TCR-dependent process. Immunity. 2002 Nov; 17(5):605-15.
Score: 0.009
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Freiberg BA, Kupfer H, Maslanik W, Delli J, Kappler J, Zaller DM, Kupfer A. Staging and resetting T cell activation in SMACs. Nat Immunol. 2002 Oct; 3(10):911-7.
Score: 0.009
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Roehm NW, Marrack P, Kappler JW. Antigen-specific, H-2-restricted helper T cell hybridomas. J Exp Med. 1982 Jul 01; 156(1):191-204.
Score: 0.009
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Marrack P, Graham SD, Kushnir E, Leibson HJ, Roehm N, Kappler JW. Nonspecific factors in B cell responses. Immunol Rev. 1982; 63:33-49.
Score: 0.009
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Lang P, Stolpa JC, Freiberg BA, Crawford F, Kappler J, Kupfer A, Cambier JC. TCR-induced transmembrane signaling by peptide/MHC class II via associated Ig-alpha/beta dimers. Science. 2001 Feb 23; 291(5508):1537-40.
Score: 0.008
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Marrack P, Kappler JW. The role of H-2-linked genes in helper T cell function. VII. Expression of I region and immune response genes by B cells in bystander help assays. J Exp Med. 1980 Nov 01; 152(5):1274-88.
Score: 0.008
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Vella AT, Mitchell T, Groth B, Linsley PS, Green JM, Thompson CB, Kappler JW, Marrack P. CD28 engagement and proinflammatory cytokines contribute to T cell expansion and long-term survival in vivo. J Immunol. 1997 May 15; 158(10):4714-20.
Score: 0.006
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Araneo BA, Marrack PC, Kappler JW. Functional heterongeneity among the T-derived lymphocytes of the mouse. VI. Memory T cells stored in the T2 subpopulation. J Immunol. 1976 Dec; 117(6):2131-6.
Score: 0.006
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Marrack P, Kappler JW. Antigen-specific and nonspecific mediatiors of T cell/B cell cooperation. II. Two helper T cells distinguished by their antigen sensitivities. J Immunol. 1976 May; 116(5):1373-8.
Score: 0.006
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Vella AT, Scherer MT, Schultz L, Kappler JW, Marrack P. B cells are not essential for peripheral T-cell tolerance. Proc Natl Acad Sci U S A. 1996 Jan 23; 93(2):951-5.
Score: 0.006
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McCormack JE, Kappler J, Marrack P. Stimulation with specific antigen can block superantigen-mediated deletion of T cells in vivo. Proc Natl Acad Sci U S A. 1994 Mar 15; 91(6):2086-90.
Score: 0.005
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Hugo P, Kappler JW, Godfrey DI, Marrack PC. Thymic epithelial cell lines that mediate positive selection can also induce thymocyte clonal deletion. J Immunol. 1994 Feb 01; 152(3):1022-31.
Score: 0.005
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Golde WT, McDuffie M, Kappler J, Marrack P. Identification of a new cell surface glycoprotein with accessory function in murine T cell responses. J Immunol. 1990 Feb 01; 144(3):804-10.
Score: 0.004
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Kotzin BL, Kappler JW, Marrack PC, Herron LR. T cell tolerance to self antigens in New Zealand hybrid mice with lupus-like disease. J Immunol. 1989 Jul 01; 143(1):89-94.
Score: 0.004
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van Ewijk W, Ron Y, Monaco J, Kappler J, Marrack P, Le Meur M, Gerlinger P, Durand B, Benoist C, Mathis D. Compartmentalization of MHC class II gene expression in transgenic mice. Cell. 1988 May 06; 53(3):357-70.
Score: 0.003
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Finkel TH, McDuffie M, Kappler JW, Marrack P, Cambier JC. Both immature and mature T cells mobilize Ca2+ in response to antigen receptor crosslinking. Nature. 1987 Nov 12-18; 330(6144):179-81.
Score: 0.003
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Gay D, Kappler J, Marrack P. L3T4 interacts with class II molecules on target cells. Ann Inst Pasteur Immunol. 1987 Jan-Feb; 138(1):127-31.
Score: 0.003
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Golde WT, Gay D, Kappler J, Marrack P. The role of LFA-1 in class II restricted, antigen-specific T-cell responses. Cell Immunol. 1986 Nov; 103(1):73-83.
Score: 0.003
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Shimonkevitz R, Colon S, Kappler JW, Marrack P, Grey HM. Antigen recognition by H-2-restricted T cells. II. A tryptic ovalbumin peptide that substitutes for processed antigen. J Immunol. 1984 Oct; 133(4):2067-74.
Score: 0.003
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Malissen B, Price MP, Goverman JM, McMillan M, White J, Kappler J, Marrack P, Pierres A, Pierres M, Hood L. Gene transfer of H-2 class II genes: antigen presentation by mouse fibroblast and hamster B-cell lines. Cell. 1984 Feb; 36(2):319-27.
Score: 0.003
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Wilde DB, Marrack P, Kappler J, Dialynas DP, Fitch FW. Evidence implicating L3T4 in class II MHC antigen reactivity; monoclonal antibody GK1.5 (anti-L3T4a) blocks class II MHC antigen-specific proliferation, release of lymphokines, and binding by cloned murine helper T lymphocyte lines. J Immunol. 1983 Nov; 131(5):2178-83.
Score: 0.003
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Birmingham JR, Chesnut RW, Kappler JW, Marrack P, Kubo R, Grey HM. Antigen presentation to T cell hybridomas by a macrophage cell line: an inducible function. J Immunol. 1982 Mar; 128(3):1491-2.
Score: 0.002
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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