 Connection
James DeGregori to Aging
This is a "connection" page, showing publications James DeGregori has written about Aging.
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Connection Strength |
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4.248 |
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De Dominici M, DeGregori J. Of Barriers and Loops-How Evolution Limits Most Cancer Risks to Older Ages. Cancer Discov. 2026 Jan 12; 16(1):16-34.
Score: 0.435
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Henry CJ, DeGregori J. Modelling the ageing dependence of cancer evolutionary trajectories. Nat Rev Cancer. 2025 Oct; 25(10):757-780.
Score: 0.420
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DeGregori J, Seidl KJ, Montano M. Aging and Cancer-Inextricably Linked Across the Lifespan. Aging Cell. 2025 04; 24(4):e14483.
Score: 0.406
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DeGregori J. Aging, inflammation, and HSC. Blood. 2020 07 09; 136(2):153-154.
Score: 0.297
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Laconi E, Marongiu F, DeGregori J. Cancer as a disease of old age: changing mutational and microenvironmental landscapes. Br J Cancer. 2020 03; 122(7):943-952.
Score: 0.288
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Rozhok A, DeGregori J. A generalized theory of age-dependent carcinogenesis. Elife. 2019 04 29; 8.
Score: 0.273
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Bilousova G, DeGregori J. Elimination of unfit cells in young and ageing skin. Nature. 2019 04; 568(7752):318-319.
Score: 0.272
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Rozhok AI, DeGregori J. The evolution of lifespan and age-dependent cancer risk. Trends Cancer. 2016 10; 2(10):552-560.
Score: 0.228
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Henry CJ, Casás-Selves M, Kim J, Zaberezhnyy V, Aghili L, Daniel AE, Jimenez L, Azam T, McNamee EN, Clambey ET, Klawitter J, Serkova NJ, Tan AC, Dinarello CA, DeGregori J. Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors. J Clin Invest. 2015 Dec; 125(12):4666-80.
Score: 0.215
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Rozhok AI, Salstrom JL, DeGregori J. Stochastic modeling indicates that aging and somatic evolution in the hematopoetic system are driven by non-cell-autonomous processes. Aging (Albany NY). 2014 Dec; 6(12):1033-48.
Score: 0.201
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DeGregori J. Challenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age? Oncogene. 2013 Apr 11; 32(15):1869-75.
Score: 0.170
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Henry CJ, Marusyk A, DeGregori J. Aging-associated changes in hematopoiesis and leukemogenesis: what's the connection? Aging (Albany NY). 2011 Jun; 3(6):643-56.
Score: 0.158
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Henry CJ, Marusyk A, Zaberezhnyy V, Adane B, DeGregori J. Declining lymphoid progenitor fitness promotes aging-associated leukemogenesis. Proc Natl Acad Sci U S A. 2010 Dec 14; 107(50):21713-8.
Score: 0.152
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Marusyk A, DeGregori J. Declining cellular fitness with age promotes cancer initiation by selecting for adaptive oncogenic mutations. Biochim Biophys Acta. 2008 Jan; 1785(1):1-11.
Score: 0.123
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Dujon AM, Asselin K, Lemaître JF, Capp JP, Pujol P, Ujvari B, DeGregori J, Nedelcu AM, Thomas F. The Role of Selection for Function in Aging and Chronic Diseases: A Novel Evolutionary Perspective. Aging Cell. 2026 01; 25(1):e70207.
Score: 0.106
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Marongiu F, DeGregori J. The sculpting of somatic mutational landscapes by evolutionary forces and their impacts on aging-related disease. Mol Oncol. 2022 09; 16(18):3238-3258.
Score: 0.085
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Hamilton JAG, Lee MY, Hunter R, Ank RS, Story JY, Talekar G, Sisroe T, Ballak DB, Fedanov A, Porter CC, Eisenmesser EZ, Dinarello CA, Raikar SS, DeGregori J, Henry CJ. Interleukin-37 improves T-cell-mediated immunity and chimeric antigen receptor T-cell therapy in aged backgrounds. Aging Cell. 2021 02; 20(2):e13309.
Score: 0.077
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DeGregori J, Pharoah P, Sasieni P, Swanton C. Cancer Screening, Surrogates of Survival, and the Soma. Cancer Cell. 2020 10 12; 38(4):433-437.
Score: 0.075
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DeGregori J. Of mice, genes and aging. Haematologica. 2020; 105(2):246-248.
Score: 0.072
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Guida JL, Ahles TA, Belsky D, Campisi J, Cohen HJ, DeGregori J, Fuldner R, Ferrucci L, Gallicchio L, Gavrilov L, Gavrilova N, Green PA, Jhappan C, Kohanski R, Krull K, Mandelblatt J, Ness KK, O'Mara A, Price N, Schrack J, Studenski S, Theou O, Tracy RP, Hurria A. Measuring Aging and Identifying Aging Phenotypes in Cancer Survivors. J Natl Cancer Inst. 2019 12 01; 111(12):1245-1254.
Score: 0.071
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Davizon-Castillo P, McMahon B, Aguila S, Bark D, Ashworth K, Allawzi A, Campbell RA, Montenont E, Nemkov T, D'Alessandro A, Clendenen N, Shih L, Sanders NA, Higa K, Cox A, Padilla-Romo Z, Hernandez G, Wartchow E, Trahan GD, Nozik-Grayck E, Jones K, Pietras EM, DeGregori J, Rondina MT, Di Paola J. TNF-a-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging. Blood. 2019 08 29; 134(9):727-740.
Score: 0.069
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Yadav VK, DeGregori J, De S. The landscape of somatic mutations in protein coding genes in apparently benign human tissues carries signatures of relaxed purifying selection. Nucleic Acids Res. 2016 Mar 18; 44(5):2075-84.
Score: 0.055
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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