 Connection
James DeGregori to Mutation
This is a "connection" page, showing publications James DeGregori has written about Mutation.
|
|
| |
Connection Strength |
|
 |
|
 |
| |
2.755 |
|
|
|
-
Pham-Danis C, Gehrke S, Danis E, Rozhok AI, Daniels MW, Gao D, Collins C, Paola JTD, D'Alessandro A, DeGregori J. Urea Cycle Sustains Cellular Energetics upon EGFR Inhibition in EGFR-Mutant NSCLC. Mol Cancer Res. 2019 06; 17(6):1351-1364.
Score: 0.264
-
DeGregori J. Connecting Cancer to Its Causes Requires Incorporation of Effects on Tissue Microenvironments. Cancer Res. 2017 11 15; 77(22):6065-6068.
Score: 0.236
-
Liggett LA, DeGregori J. Changing mutational and adaptive landscapes and the genesis of cancer. Biochim Biophys Acta Rev Cancer. 2017 Apr; 1867(2):84-94.
Score: 0.229
-
Rozhok AI, DeGregori J. Toward an evolutionary model of cancer: Considering the mechanisms that govern the fate of somatic mutations. Proc Natl Acad Sci U S A. 2015 Jul 21; 112(29):8914-21.
Score: 0.205
-
Marusyk A, Casás-Selves M, Henry CJ, Zaberezhnyy V, Klawitter J, Christians U, DeGregori J. Irradiation alters selection for oncogenic mutations in hematopoietic progenitors. Cancer Res. 2009 Sep 15; 69(18):7262-9.
Score: 0.137
-
Marusyk A, DeGregori J. Declining cellular fitness with age promotes cancer initiation by selecting for adaptive oncogenic mutations. Biochim Biophys Acta. 2008 Jan; 1785(1):1-11.
Score: 0.120
-
Marusyk A, DeGregori J. Replicational stress selects for p53 mutation. Cell Cycle. 2007 Sep 01; 6(17):2148-51.
Score: 0.118
-
Henry CJ, DeGregori J. Modelling the ageing dependence of cancer evolutionary trajectories. Nat Rev Cancer. 2025 Oct; 25(10):757-780.
Score: 0.103
-
Lim EL, DeGregori J. The Nature and Nurture of Carcinogenesis. Cancer Discov. 2025 Jun 03; 15(6):1090-1092.
Score: 0.102
-
Park HJ, Gregory MA, Zaberezhnyy V, Goodspeed A, Jordan CT, Kieft JS, DeGregori J. Therapeutic resistance in acute myeloid leukemia cells is mediated by a novel ATM/mTOR pathway regulating oxidative phosphorylation. Elife. 2022 10 19; 11.
Score: 0.085
-
Pietras EM, DeGregori J. Dangerous Liaisons between Tet2 Mutation, Inflammatory Monocytes, and Leukemogenesis. Cancer Discov. 2022 10 05; 12(10):2234-2236.
Score: 0.085
-
Evans EJ, DeGregori J. Dissecting stepwise mutational impairment of megakaryopoiesis in a model of Down syndrome-associated leukemia. J Clin Invest. 2022 07 15; 132(14).
Score: 0.083
-
Marongiu F, DeGregori J. The sculpting of somatic mutational landscapes by evolutionary forces and their impacts on aging-related disease. Mol Oncol. 2022 09; 16(18):3238-3258.
Score: 0.083
-
De Dominici M, DeGregori J. Shedding Light on Mutant Clonal Dynamics and Cancer Risk in the Skin. Cancer Discov. 2021 02; 11(2):227-229.
Score: 0.075
-
Laconi E, Marongiu F, DeGregori J. Cancer as a disease of old age: changing mutational and microenvironmental landscapes. Br J Cancer. 2020 03; 122(7):943-952.
Score: 0.070
-
Liggett LA, Sharma A, De S, DeGregori J. FERMI: A Novel Method for Sensitive Detection of Rare Mutations in Somatic Tissue. G3 (Bethesda). 2019 09 04; 9(9):2977-2987.
Score: 0.068
-
Rozhok A, DeGregori J. Somatic maintenance impacts the evolution of mutation rate. BMC Evol Biol. 2019 08 23; 19(1):172.
Score: 0.068
-
Rozhok A, DeGregori J. A generalized theory of age-dependent carcinogenesis. Elife. 2019 04 29; 8.
Score: 0.067
-
Higa KC, DeGregori J. Decoy fitness peaks, tumor suppression, and aging. Aging Cell. 2019 06; 18(3):e12938.
Score: 0.066
-
Rozhok AI, Salstrom JL, DeGregori J. Stochastic modeling reveals an evolutionary mechanism underlying elevated rates of childhood leukemia. Proc Natl Acad Sci U S A. 2016 Jan 26; 113(4):1050-5.
Score: 0.053
-
Rozhok AI, Salstrom JL, DeGregori J. Stochastic modeling indicates that aging and somatic evolution in the hematopoetic system are driven by non-cell-autonomous processes. Aging (Albany NY). 2014 Dec; 6(12):1033-48.
Score: 0.049
-
DeGregori J. Challenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age? Oncogene. 2013 Apr 11; 32(15):1869-75.
Score: 0.042
-
Henry CJ, Marusyk A, DeGregori J. Aging-associated changes in hematopoiesis and leukemogenesis: what's the connection? Aging (Albany NY). 2011 Jun; 3(6):643-56.
Score: 0.039
-
Fleenor CJ, Marusyk A, DeGregori J. Ionizing radiation and hematopoietic malignancies: altering the adaptive landscape. Cell Cycle. 2010 Aug 01; 9(15):3005-11.
Score: 0.036
-
Marusyk A, Porter CC, Zaberezhnyy V, DeGregori J. Irradiation selects for p53-deficient hematopoietic progenitors. PLoS Biol. 2010 Mar 02; 8(3):e1000324.
Score: 0.035
-
Marusyk A, Wheeler LJ, Mathews CK, DeGregori J. p53 mediates senescence-like arrest induced by chronic replicational stress. Mol Cell Biol. 2007 Aug; 27(15):5336-51.
Score: 0.029
-
Yu B, Suehiro Y, Johnson BJ, Lee ES, Li D, Huang Y, Johnson J, Ou G, DeGregori J, Mitani S, Xue D. Cathepsin B protease mediates high population density-induced mutagenesis to drive genome evolution and competitive growth. Nat Commun. 2026 May 04; 17(1).
Score: 0.027
-
DeGregori J. Surprising dependency for retinoblastoma protein in ras-mediated tumorigenesis. Mol Cell Biol. 2006 Feb; 26(4):1165-9.
Score: 0.027
-
Schleicher WE, Hoag B, De Dominici M, DeGregori J, Pietras EM. CHIP: a clonal odyssey of the bone marrow niche. J Clin Invest. 2024 08 01; 134(15).
Score: 0.024
-
Bramwell G, DeGregori J, Thomas F, Ujvari B. Transmissible cancers, the genomes that do not melt down. Evolution. 2024 Jul 01; 78(7):1205-1211.
Score: 0.024
-
Li FX, Zhu JW, Hogan CJ, DeGregori J. Defective gene expression, S phase progression, and maturation during hematopoiesis in E2F1/E2F2 mutant mice. Mol Cell Biol. 2003 May; 23(10):3607-22.
Score: 0.022
-
DeGregori J. The genetics of the E2F family of transcription factors: shared functions and unique roles. Biochim Biophys Acta. 2002 Jun 21; 1602(2):131-50.
Score: 0.021
-
Florez MA, Tran BT, Wathan TK, DeGregori J, Pietras EM, King KY. Clonal hematopoiesis: Mutation-specific adaptation to environmental change. Cell Stem Cell. 2022 06 02; 29(6):882-904.
Score: 0.021
-
Aghili L, Foo J, DeGregori J, De S. Patterns of somatically acquired amplifications and deletions in apparently normal tissues of ovarian cancer patients. Cell Rep. 2014 May 22; 7(4):1310-9.
Score: 0.012
-
Ostrow SL, Barshir R, DeGregori J, Yeger-Lotem E, Hershberg R. Cancer evolution is associated with pervasive positive selection on globally expressed genes. PLoS Genet. 2014 Mar; 10(3):e1004239.
Score: 0.012
-
Angus SP, Fribourg AF, Markey MP, Williams SL, Horn HF, DeGregori J, Kowalik TF, Fukasawa K, Knudsen ES. Active RB elicits late G1/S inhibition. Exp Cell Res. 2002 Jun 10; 276(2):201-13.
Score: 0.005
-
Cripe TP, Dunphy EJ, Holub AD, Saini A, Vasi NH, Mahller YY, Collins MH, Snyder JD, Krasnykh V, Curiel DT, Wickham TJ, DeGregori J, Bergelson JM, Currier MA. Fiber knob modifications overcome low, heterogeneous expression of the coxsackievirus-adenovirus receptor that limits adenovirus gene transfer and oncolysis for human rhabdomyosarcoma cells. Cancer Res. 2001 Apr 01; 61(7):2953-60.
Score: 0.005
-
Schwertfeger KL, Hunter S, Heasley LE, Levresse V, Leon RP, DeGregori J, Anderson SM. Prolactin stimulates activation of c-jun N-terminal kinase (JNK). Mol Endocrinol. 2000 Oct; 14(10):1592-602.
Score: 0.005
-
Leone G, DeGregori J, Sears R, Jakoi L, Nevins JR. Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. Nature. 1997 May 22; 387(6631):422-6.
Score: 0.004
|
Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
|