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Connection

Kennon Heard to Acetaminophen

This is a "connection" page, showing publications Kennon Heard has written about Acetaminophen.

 
Connection Strength
  
 
 
9.297
  
  1. Monte AA, Sonn B, Saben J, Rumack BH, Reynolds KM, Dart RC, Heard KJ. The Genomics of Elevated ALT and Adducts in Therapeutic Acetaminophen Treatment: a Pilot Study. J Med Toxicol. 2021 04; 17(2):160-167.
    View in: PubMed
    Score: 0.623
  2. Heard K, Anderson VE, Lavonas EJ, Dart RC, Green JL. Serum paracetamol-protein adducts in ambulatory subjects: Relationship to recent reported paracetamol use. Biomarkers. 2018 May; 23(3):288-292.
    View in: PubMed
    Score: 0.512
  3. Heard K, Anderson V, Dart RC, Kile D, Lavonas EJ, Green JL. Serum Acetaminophen Protein Adduct Concentrations in Pediatric Emergency Department Patients. J Pediatr Gastroenterol Nutr. 2017 04; 64(4):533-535.
    View in: PubMed
    Score: 0.488
  4. Yip L, Heard K. Potential adjunct treatment for high-risk acetaminophen overdose. Clin Toxicol (Phila). 2016 Jun; 54(5):459.
    View in: PubMed
    Score: 0.452
  5. Heard K, Green JL, Anderson V, Bucher-Bartelson B, Dart RC. Paracetamol (acetaminophen) protein adduct concentrations during therapeutic dosing. Br J Clin Pharmacol. 2016 Mar; 81(3):562-8.
    View in: PubMed
    Score: 0.449
  6. Seifert SA, Kovnat D, Anderson VE, Green JL, Dart RC, Heard KJ. Acute hepatotoxicity associated with therapeutic doses of intravenous acetaminophen. Clin Toxicol (Phila). 2016 Mar; 54(3):282-5.
    View in: PubMed
    Score: 0.449
  7. Heard K, Green JL, Anderson V, Bucher-Bartelson B, Dart RC. A randomized, placebo-controlled trial to determine the course of aminotransferase elevation during prolonged acetaminophen administration. BMC Pharmacol Toxicol. 2014 Jul 22; 15:39.
    View in: PubMed
    Score: 0.405
  8. Heard K, Bui A, Mlynarchek SL, Green JL, Bond GR, Clark RF, Kozer E, Koff RS, Dart RC. Toxicity from repeated doses of acetaminophen in children: assessment of causality and dose in reported cases. Am J Ther. 2014 May-Jun; 21(3):174-83.
    View in: PubMed
    Score: 0.399
  9. Varney SM, Buchanan JA, Kokko J, Heard K. Acetylcysteine for acetaminophen overdose in patients who weigh >100 kg. Am J Ther. 2014 May-Jun; 21(3):159-63.
    View in: PubMed
    Score: 0.399
  10. Heard K, Rumack BH, Green JL, Bucher-Bartelson B, Heard S, Bronstein AC, Dart RC. A single-arm clinical trial of a 48-hour intravenous N-acetylcysteine protocol for treatment of acetaminophen poisoning. Clin Toxicol (Phila). 2014 Jun; 52(5):512-8.
    View in: PubMed
    Score: 0.397
  11. Heard K, Green J. Acetylcysteine therapy for acetaminophen poisoning. Curr Pharm Biotechnol. 2012 Aug; 13(10):1917-23.
    View in: PubMed
    Score: 0.353
  12. Yin S, Heard KJ. Complex suicide: self-incineration and acetaminophen overdose. Injury. 2012 Jan; 43(1):124-5.
    View in: PubMed
    Score: 0.328
  13. Heard KJ, Green JL, James LP, Judge BS, Zolot L, Rhyee S, Dart RC. Acetaminophen-cysteine adducts during therapeutic dosing and following overdose. BMC Gastroenterol. 2011 Mar 14; 11:20.
    View in: PubMed
    Score: 0.321
  14. Wang GS, Monte A, Bagdure D, Heard K. Hepatic failure despite early acetylcysteine following large acetaminophen-diphenhydramine overdose. Pediatrics. 2011 Apr; 127(4):e1077-80.
    View in: PubMed
    Score: 0.321
  15. Heard K. Asymptomatic alanine aminotransferase elevations with therapeutic doses of acetaminophen. Clin Toxicol (Phila). 2011 Feb; 49(2):90-3.
    View in: PubMed
    Score: 0.318
  16. Alhelail MA, Hoppe JA, Rhyee SH, Heard KJ. Clinical course of repeated supratherapeutic ingestion of acetaminophen. Clin Toxicol (Phila). 2011 Feb; 49(2):108-12.
    View in: PubMed
    Score: 0.318
  17. Heard KJ, Green JL, Dart RC. Serum alanine aminotransferase elevation during 10 days of acetaminophen use in nondrinkers. Pharmacotherapy. 2010 Aug; 30(8):818-22.
    View in: PubMed
    Score: 0.307
  18. Heard KJ. Acetylcysteine for acetaminophen poisoning. N Engl J Med. 2008 Jul 17; 359(3):285-92.
    View in: PubMed
    Score: 0.267
  19. Heard K, Green JL, Bailey JE, Bogdan GM, Dart RC. A randomized trial to determine the change in alanine aminotransferase during 10 days of paracetamol (acetaminophen) administration in subjects who consume moderate amounts of alcohol. Aliment Pharmacol Ther. 2007 Jul 15; 26(2):283-90.
    View in: PubMed
    Score: 0.249
  20. Monte AA, Vest A, Reisz JA, Berninzoni D, Hart C, Dylla L, D'Alessandro A, Heard KJ, Wood C, Pattee J. A Multi-Omic Mosaic Model of Acetaminophen Induced Alanine Aminotransferase Elevation. J Med Toxicol. 2023 07; 19(3):255-261.
    View in: PubMed
    Score: 0.187
  21. Monte AA, Arriaga Mackenzie I, Pattee J, Kaiser S, Willems E, Rumack B, Reynolds KM, Dart RC, Heard KJ. Genetic variants associated with ALT elevation from therapeutic acetaminophen. Clin Toxicol (Phila). 2022 11; 60(11):1198-1204.
    View in: PubMed
    Score: 0.178
  22. Arnold CG, Dylla L, Monte AA, Heard K, Heard S, D'Alessandro A, Reynolds K, Dart R, Rumack B, Sonn B. Metabolomic Evaluation of N-Acetyl-p-Benzoquinone Imine Protein Adduct Formation with Therapeutic Acetaminophen Administration: Sex-based Physiologic Differences. J Med Toxicol. 2022 10; 18(4):297-310.
    View in: PubMed
    Score: 0.175
  23. Sonn BJ, Heard KJ, Heard SM, D'Alessandro A, Reynolds KM, Dart RC, Rumack BH, Monte AA. Metabolomic markers predictive of hepatic adaptation to therapeutic dosing of acetaminophen. Clin Toxicol (Phila). 2022 Feb; 60(2):221-230.
    View in: PubMed
    Score: 0.163
  24. Wong A, Heard K, Graudins A, Dart R, Sivilotti MLA. Adducts Post Acetaminophen Overdose Treated with a 12-Hour vs 20-Hour Acetylcysteine Infusion. J Med Toxicol. 2020 04; 16(2):188-194.
    View in: PubMed
    Score: 0.148
  25. Lucyk SN, Yarema MC, Sivilotti ML, Johnson DW, Nettel-Aguirre A, Victorino C, Bailey B, Dart RC, Heard K, Spyker DA, Rumack BH. Outcomes of Patients With Premature Discontinuation of the 21-h Intravenous N-Acetylcysteine Protocol After Acute Acetaminophen Overdose. J Emerg Med. 2016 Apr; 50(4):629-37.
    View in: PubMed
    Score: 0.113
  26. Zurlinden TJ, Heard K, Reisfeld B. A novel approach for estimating ingested dose associated with paracetamol overdose. Br J Clin Pharmacol. 2016 Apr; 81(4):634-45.
    View in: PubMed
    Score: 0.111
  27. Frey SM, Wiegand TJ, Green JL, Heard KJ, Wilkins DG, Gorodetsky RM, Dart RC. Confirming the Causative Role of Acetaminophen in Indeterminate Acute Liver Failure Using Acetaminophen-Cysteine Adducts. J Med Toxicol. 2015 Jun; 11(2):218-22.
    View in: PubMed
    Score: 0.107
  28. Rumack B, Heard K, Green J, Albert D, Bucher-Bartelson B, Bodmer M, Sivilotti ML, Dart RC. Effect of therapeutic doses of acetaminophen (up to 4 g/day) on serum alanine aminotransferase levels in subjects consuming ethanol: systematic review and meta-analysis of randomized controlled trials. Pharmacotherapy. 2012 Sep; 32(9):784-91.
    View in: PubMed
    Score: 0.088
  29. Heard K, Schaeffer TH. Massive acetylcysteine overdose associated with cerebral edema and seizures. Clin Toxicol (Phila). 2011 Jun; 49(5):423-5.
    View in: PubMed
    Score: 0.081
  30. Vogel J, Heard KJ, Carlson C, Lange C, Mitchell G. Dental pain as a risk factor for accidental acetaminophen overdose: a case-control study. Am J Emerg Med. 2011 Nov; 29(9):1125-9.
    View in: PubMed
    Score: 0.078
  31. Bebarta VS, Kao L, Froberg B, Clark RF, Lavonas E, Qi M, Delgado J, McDonagh J, Arnold T, Odujebe O, O'Malley G, Lares C, Aguilera E, Dart R, Heard K, Stanford C, Kokko J, Bogdan G, Mendoza C, Mlynarchek S, Rhyee S, Hoppe J, Haur W, Tan HH, Tran NN, Varney S, Zosel A, Buchanan J, Al-Helial M. A multicenter comparison of the safety of oral versus intravenous acetylcysteine for treatment of acetaminophen overdose. Clin Toxicol (Phila). 2010 Jun; 48(5):424-30.
    View in: PubMed
    Score: 0.076
  32. Dart RC, Green JL, Kuffner EK, Heard K, Sproule B, Brands B. The effects of paracetamol (acetaminophen) on hepatic tests in patients who chronically abuse alcohol - a randomized study. Aliment Pharmacol Ther. 2010 Aug; 32(3):478-86.
    View in: PubMed
    Score: 0.076
  33. Wolf SJ, Heard K, Sloan EP, Jagoda AS. Clinical policy: critical issues in the management of patients presenting to the emergency department with acetaminophen overdose. Ann Emerg Med. 2007 Sep; 50(3):292-313.
    View in: PubMed
    Score: 0.063
  34. Kuffner EK, Green JL, Bogdan GM, Knox PC, Palmer RB, Heard K, Slattery JT, Dart RC. The effect of acetaminophen (four grams a day for three consecutive days) on hepatic tests in alcoholic patients--a multicenter randomized study. BMC Med. 2007 May 30; 5:13.
    View in: PubMed
    Score: 0.062
  35. Mendoza CD, Heard K, Dart RC. Coma, metabolic acidosis and normal liver function in a child with a large serum acetaminophen level. Ann Emerg Med. 2006 Nov; 48(5):637.
    View in: PubMed
    Score: 0.059
  36. Heard K, Sloss D, Weber S, Dart RC. Overuse of over-the-counter analgesics by emergency department patients. Ann Emerg Med. 2006 Sep; 48(3):315-8.
    View in: PubMed
    Score: 0.056
  37. Daly FF, O'Malley GF, Heard K, Bogdan GM, Dart RC. Prospective evaluation of repeated supratherapeutic acetaminophen (paracetamol) ingestion. Ann Emerg Med. 2004 Oct; 44(4):393-8.
    View in: PubMed
    Score: 0.051
  38. Dart RC, Mullins ME, Matoushek T, Ruha AM, Burns MM, Simone K, Beuhler MC, Heard KJ, Mazer-Amirshahi M, Stork CM, Varney SM, Funk AR, Cantrell LF, Cole JB, Banner W, Stolbach AI, Hendrickson RG, Lucyk SN, Sivilotti MLA, Su MK, Nelson LS, Rumack BH. Management of Acetaminophen Poisoning in the US and Canada: A Consensus Statement. JAMA Netw Open. 2023 08 01; 6(8):e2327739.
    View in: PubMed
    Score: 0.047
  39. Wang GS, Deakyne S, Bajaj L, Yin S, Heard K, Roosevelt G. The limited utility of screening laboratory tests and electrocardiograms in the management of unintentional asymptomatic pediatric ingestions. J Emerg Med. 2013 Jul; 45(1):34-8.
    View in: PubMed
    Score: 0.023
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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