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Connection

David Bain to Humans

This is a "connection" page, showing publications David Bain has written about Humans.

 
Connection Strength
 
 
 
0.227
 
  1. Hopkins MM, Lambert CL, Bee JS, Parupudi A, Bain DL. Determination of Interaction Parameters for Reversibly Self-Associating Antibodies: A Comparative Analysis. J Pharm Sci. 2018 07; 107(7):1820-1830.
    View in: PubMed
    Score: 0.017
  2. Bain DL, Brenowitz M, Roberts CJ. An Opportunity for Industry-Academia Partnership: Training the Next Generation of Industrial Researchers in Characterizing Higher Order Protein Structure. J Pharm Sci. 2016 12; 105(12):3483-3486.
    View in: PubMed
    Score: 0.015
  3. De Angelis RW, Maluf NK, Yang Q, Lambert JR, Bain DL. Glucocorticoid Receptor-DNA Dissociation Kinetics Measured in Vitro Reveal Exchange on the Second Time Scale. Biochemistry. 2015 Sep 01; 54(34):5306-14.
    View in: PubMed
    Score: 0.014
  4. Bain DL, De Angelis RW, Connaghan KD, Yang Q, Degala GD, Lambert JR. Dissecting Steroid Receptor Function by Analytical Ultracentrifugation. Methods Enzymol. 2015; 562:363-89.
    View in: PubMed
    Score: 0.014
  5. De Angelis RW, Yang Q, Miura MT, Bain DL. Dissection of androgen receptor-promoter interactions: steroid receptors partition their interaction energetics in parallel with their phylogenetic divergence. J Mol Biol. 2013 Nov 15; 425(22):4223-35.
    View in: PubMed
    Score: 0.012
  6. Connaghan KD, Miura MT, Maluf NK, Lambert JR, Bain DL. Analysis of a glucocorticoid-estrogen receptor chimera reveals that dimerization energetics are under ionic control. Biophys Chem. 2013 Feb; 172:8-17.
    View in: PubMed
    Score: 0.012
  7. Bain DL, Yang Q, Connaghan KD, Robblee JP, Miura MT, Degala GD, Lambert JR, Maluf NK. Glucocorticoid receptor-DNA interactions: binding energetics are the primary determinant of sequence-specific transcriptional activity. J Mol Biol. 2012 Sep 07; 422(1):18-32.
    View in: PubMed
    Score: 0.011
  8. Robblee JP, Miura MT, Bain DL. Glucocorticoid receptor-promoter interactions: energetic dissection suggests a framework for the specificity of steroid receptor-mediated gene regulation. Biochemistry. 2012 Jun 05; 51(22):4463-72.
    View in: PubMed
    Score: 0.011
  9. Moody AD, Miura MT, Connaghan KD, Bain DL. Thermodynamic dissection of estrogen receptor-promoter interactions reveals that steroid receptors differentially partition their self-association and promoter binding energetics. Biochemistry. 2012 Jan 24; 51(3):739-49.
    View in: PubMed
    Score: 0.011
  10. Connaghan KD, Moody AD, Robblee JP, Lambert JR, Bain DL. From steroid receptors to cytokines: the thermodynamics of self-associating systems. Biophys Chem. 2011 Nov; 159(1):24-32.
    View in: PubMed
    Score: 0.010
  11. Connaghan KD, Heneghan AF, Miura MT, Bain DL. Na(+) and K(+) allosterically regulate cooperative DNA binding by the human progesterone receptor. Biochemistry. 2010 Jan 26; 49(3):422-31.
    View in: PubMed
    Score: 0.010
  12. Connaghan-Jones KD, Bain DL. Using thermodynamics to understand progesterone receptor function: method and theory. Methods Enzymol. 2009; 455:41-70.
    View in: PubMed
    Score: 0.009
  13. Connaghan-Jones KD, Heneghan AF, Miura MT, Bain DL. Thermodynamic dissection of progesterone receptor interactions at the mouse mammary tumor virus promoter: monomer binding and strong cooperativity dominate the assembly reaction. J Mol Biol. 2008 Apr 04; 377(4):1144-60.
    View in: PubMed
    Score: 0.008
  14. Heneghan AF, Connaghan-Jones KD, Miura MT, Bain DL. Coactivator assembly at the promoter: efficient recruitment of SRC2 is coupled to cooperative DNA binding by the progesterone receptor. Biochemistry. 2007 Oct 02; 46(39):11023-32.
    View in: PubMed
    Score: 0.008
  15. Connaghan-Jones KD, Heneghan AF, Miura MT, Bain DL. Thermodynamic analysis of progesterone receptor-promoter interactions reveals a molecular model for isoform-specific function. Proc Natl Acad Sci U S A. 2007 Feb 13; 104(7):2187-92.
    View in: PubMed
    Score: 0.008
  16. Bain DL, Heneghan AF, Connaghan-Jones KD, Miura MT. Nuclear receptor structure: implications for function. Annu Rev Physiol. 2007; 69:201-20.
    View in: PubMed
    Score: 0.008
  17. Connaghan-Jones KD, Heneghan AF, Miura MT, Bain DL. Hydrodynamic analysis of the human progesterone receptor A-isoform reveals that self-association occurs in the micromolar range. Biochemistry. 2006 Oct 03; 45(39):12090-9.
    View in: PubMed
    Score: 0.008
  18. Heneghan AF, Connaghan-Jones KD, Miura MT, Bain DL. Cooperative DNA binding by the B-isoform of human progesterone receptor: thermodynamic analysis reveals strongly favorable and unfavorable contributions to assembly. Biochemistry. 2006 Mar 14; 45(10):3285-96.
    View in: PubMed
    Score: 0.007
  19. Heneghan AF, Berton N, Miura MT, Bain DL. Self-association energetics of an intact, full-length nuclear receptor: the B-isoform of human progesterone receptor dimerizes in the micromolar range. Biochemistry. 2005 Jul 12; 44(27):9528-37.
    View in: PubMed
    Score: 0.007
  20. Bain DL, Franden MA, McManaman JL, Takimoto GS, Horwitz KB. The N-terminal region of human progesterone B-receptors: biophysical and biochemical comparison to A-receptors. J Biol Chem. 2001 Jun 29; 276(26):23825-31.
    View in: PubMed
    Score: 0.005
  21. Bain DL, Franden MA, McManaman JL, Takimoto GS, Horwitz KB. The N-terminal region of the human progesterone A-receptor. Structural analysis and the influence of the DNA binding domain. J Biol Chem. 2000 Mar 10; 275(10):7313-20.
    View in: PubMed
    Score: 0.005
  22. Hudson WH, Vera IMS, Nwachukwu JC, Weikum ER, Herbst AG, Yang Q, Bain DL, Nettles KW, Kojetin DJ, Ortlund EA. Cryptic glucocorticoid receptor-binding sites pervade genomic NF-?B response elements. Nat Commun. 2018 04 06; 9(1):1337.
    View in: PubMed
    Score: 0.004
  23. Gandhi AV, Pothecary MR, Bain DL, Carpenter JF. Some Lessons Learned From a Comparison Between Sedimentation Velocity Analytical Ultracentrifugation and Size Exclusion Chromatography to Characterize and Quantify Protein Aggregates. J Pharm Sci. 2017 08; 106(8):2178-2186.
    View in: PubMed
    Score: 0.004
  24. Cochrane DR, Jacobsen BM, Connaghan KD, Howe EN, Bain DL, Richer JK. Progestin regulated miRNAs that mediate progesterone receptor action in breast cancer. Mol Cell Endocrinol. 2012 May 15; 355(1):15-24.
    View in: PubMed
    Score: 0.003
  25. Takimoto GS, Tung L, Abdel-Hafiz H, Abel MG, Sartorius CA, Richer JK, Jacobsen BM, Bain DL, Horwitz KB. Functional properties of the N-terminal region of progesterone receptors and their mechanistic relationship to structure. J Steroid Biochem Mol Biol. 2003 Jun; 85(2-5):209-19.
    View in: PubMed
    Score: 0.002
  26. Graham JD, Bain DL, Richer JK, Jackson TA, Tung L, Horwitz KB. Thoughts on tamoxifen resistant breast cancer. Are coregulators the answer or just a red herring? J Steroid Biochem Mol Biol. 2000 Nov 30; 74(5):255-9.
    View in: PubMed
    Score: 0.001
  27. Graham JD, Bain DL, Richer JK, Jackson TA, Tung L, Horwitz KB. Nuclear receptor conformation, coregulators, and tamoxifen-resistant breast cancer. Steroids. 2000 Oct-Nov; 65(10-11):579-84.
    View in: PubMed
    Score: 0.001
  28. Jackson TA, Richer JK, Bain DL, Takimoto GS, Tung L, Horwitz KB. The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT. Mol Endocrinol. 1997 Jun; 11(6):693-705.
    View in: PubMed
    Score: 0.001
  29. Horwitz KB, Jackson TA, Bain DL, Richer JK, Takimoto GS, Tung L. Nuclear receptor coactivators and corepressors. Mol Endocrinol. 1996 Oct; 10(10):1167-77.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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