 Connection
Wendy Macklin to Myelin Sheath
This is a "connection" page, showing publications Wendy Macklin has written about Myelin Sheath.
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Connection Strength |
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9.956 |
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Macklin W, Allen T. Meeting the need for myelin. Science. 2026 Jan 22; 391(6783):351-352.
Score: 0.814
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Brown TL, Hashimoto H, Finseth LT, Wood TL, Macklin WB. PAK1 Positively Regulates Oligodendrocyte Morphology and Myelination. J Neurosci. 2021 03 03; 41(9):1864-1877.
Score: 0.576
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Brown TL, Macklin WB. The Actin Cytoskeleton in Myelinating Cells. Neurochem Res. 2020 Mar; 45(3):684-693.
Score: 0.505
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Preston MA, Finseth LT, Bourne JN, Macklin WB. A novel myelin protein zero transgenic zebrafish designed for rapid readout of in vivo myelination. Glia. 2019 04; 67(4):650-667.
Score: 0.500
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Gould EA, Busquet N, Shepherd D, Dietz RM, Herson PS, Simoes de Souza FM, Li A, George NM, Restrepo D, Macklin WB. Mild myelin disruption elicits early alteration in behavior and proliferation in the subventricular zone. Elife. 2018 02 13; 7.
Score: 0.470
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Ahrendsen JT, Harlow DE, Finseth LT, Bourne JN, Hickey SP, Gould EA, Culp CM, Macklin WB. The Protein Tyrosine Phosphatase Shp2 Regulates Oligodendrocyte Differentiation and Early Myelination and Contributes to Timely Remyelination. J Neurosci. 2018 01 24; 38(4):787-802.
Score: 0.464
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Verden D, Macklin WB. Neuroprotection by central nervous system remyelination: Molecular, cellular, and functional considerations. J Neurosci Res. 2016 12; 94(12):1411-1420.
Score: 0.426
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Bercury KK, Macklin WB. Dynamics and mechanisms of CNS myelination. Dev Cell. 2015 Feb 23; 32(4):447-58.
Score: 0.382
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Sachs HH, Bercury KK, Popescu DC, Narayanan SP, Macklin WB. A new model of cuprizone-mediated demyelination/remyelination. ASN Neuro. 2014; 6(5).
Score: 0.372
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Preston MA, Macklin WB. Zebrafish as a model to investigate CNS myelination. Glia. 2015 Feb; 63(2):177-93.
Score: 0.371
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Bercury KK, Dai J, Sachs HH, Ahrendsen JT, Wood TL, Macklin WB. Conditional ablation of raptor or rictor has differential impact on oligodendrocyte differentiation and CNS myelination. J Neurosci. 2014 Mar 26; 34(13):4466-80.
Score: 0.359
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Harlow DE, Macklin WB. Inhibitors of myelination: ECM changes, CSPGs and PTPs. Exp Neurol. 2014 Jan; 251:39-46.
Score: 0.349
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Ahrendsen JT, Macklin W. Signaling mechanisms regulating myelination in the central nervous system. Neurosci Bull. 2013 Apr; 29(2):199-215.
Score: 0.335
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Macklin WB. The myelin brake: when enough is enough. Sci Signal. 2010 Sep 21; 3(140):pe32.
Score: 0.281
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Flores AI, Narayanan SP, Morse EN, Shick HE, Yin X, Kidd G, Avila RL, Kirschner DA, Macklin WB. Constitutively active Akt induces enhanced myelination in the CNS. J Neurosci. 2008 Jul 09; 28(28):7174-83.
Score: 0.241
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Yoshida M, Macklin WB. Oligodendrocyte development and myelination in GFP-transgenic zebrafish. J Neurosci Res. 2005 Jul 01; 81(1):1-8.
Score: 0.196
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Mather ML, Evangelou AV, Bourne JN, Macklin WB, Wood TL. Myelin Lipid Composition in the Central Nervous System Is Regionally Distinct and Requires Mechanistic Target of Rapamycin Signaling. Glia. 2025 09; 73(9):1841-1859.
Score: 0.194
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Almeida AR, Macklin WB. Early myelination involves the dynamic and repetitive ensheathment of axons which resolves through a low and consistent stabilization rate. Elife. 2023 04 20; 12.
Score: 0.168
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Miller MJ, Haxhiu MA, Georgiadis P, Gudz TI, Kangas CD, Macklin WB. Proteolipid protein gene mutation induces altered ventilatory response to hypoxia in the myelin-deficient rat. J Neurosci. 2003 Mar 15; 23(6):2265-73.
Score: 0.167
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Dahl KD, Almeida AR, Hathaway HA, Bourne J, Brown TL, Finseth LT, Wood TL, Macklin WB. mTORC2 Loss in Oligodendrocyte Progenitor Cells Results in Regional Hypomyelination in the Central Nervous System. J Neurosci. 2023 01 25; 43(4):540-558.
Score: 0.164
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Fuss B, Afshari FS, Colello RJ, Macklin WB. Normal CNS myelination in transgenic mice overexpressing MHC class I H-2L(d) in oligodendrocytes. Mol Cell Neurosci. 2001 Aug; 18(2):221-34.
Score: 0.149
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Musah AS, Brown TL, Jeffries MA, Shang Q, Hashimoto H, Evangelou AV, Kowalski A, Batish M, Macklin WB, Wood TL. Mechanistic Target of Rapamycin Regulates the Oligodendrocyte Cytoskeleton during Myelination. J Neurosci. 2020 04 08; 40(15):2993-3007.
Score: 0.135
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Ishii A, Furusho M, Macklin W, Bansal R. Independent and cooperative roles of the Mek/ERK1/2-MAPK and PI3K/Akt/mTOR pathways during developmental myelination and in adulthood. Glia. 2019 07; 67(7):1277-1295.
Score: 0.126
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Fuss B, Baba H, Phan T, Tuohy VK, Macklin WB. Phosphodiesterase I, a novel adhesion molecule and/or cytokine involved in oligodendrocyte function. J Neurosci. 1997 Dec 01; 17(23):9095-103.
Score: 0.116
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Abi Ghanem C, Degerny C, Hussain R, Liere P, Pianos A, Tourpin S, Habert R, Macklin WB, Schumacher M, Ghoumari AM. Long-lasting masculinizing effects of postnatal androgens on myelin governed by the brain androgen receptor. PLoS Genet. 2017 Nov; 13(11):e1007049.
Score: 0.115
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Turcotte R, Rutledge DJ, Bélanger E, Dill D, Macklin WB, Côté DC. Intravital assessment of myelin molecular order with polarimetric multiphoton microscopy. Sci Rep. 2016 08 19; 6:31685.
Score: 0.106
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Greenberg ML, Weinger JG, Matheu MP, Carbajal KS, Parker I, Macklin WB, Lane TE, Cahalan MD. Two-photon imaging of remyelination of spinal cord axons by engrafted neural precursor cells in a viral model of multiple sclerosis. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):E2349-55.
Score: 0.091
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Wahl SE, McLane LE, Bercury KK, Macklin WB, Wood TL. Mammalian target of rapamycin promotes oligodendrocyte differentiation, initiation and extent of CNS myelination. J Neurosci. 2014 Mar 26; 34(13):4453-65.
Score: 0.090
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Harlow DE, Saul KE, Culp CM, Vesely EM, Macklin WB. Expression of proteolipid protein gene in spinal cord stem cells and early oligodendrocyte progenitor cells is dispensable for normal cell migration and myelination. J Neurosci. 2014 Jan 22; 34(4):1333-43.
Score: 0.089
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Wight PA, Duchala CS, Readhead C, Macklin WB. A myelin proteolipid protein-LacZ fusion protein is developmentally regulated and targeted to the myelin membrane in transgenic mice. J Cell Biol. 1993 Oct; 123(2):443-54.
Score: 0.087
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Jaini R, Popescu DC, Flask CA, Macklin WB, Tuohy VK. Myelin antigen load influences antigen presentation and severity of central nervous system autoimmunity. J Neuroimmunol. 2013 Jun 15; 259(1-2):37-46.
Score: 0.084
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Asotra K, Macklin WB. Protein kinase C activity modulates myelin gene expression in enriched oligodendrocytes. J Neurosci Res. 1993 Apr 01; 34(5):571-88.
Score: 0.084
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Hu X, Schlanger R, He W, Macklin WB, Yan R. Reversing hypomyelination in BACE1-null mice with Akt-DD overexpression. FASEB J. 2013 May; 27(5):1868-73.
Score: 0.083
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Hussain R, Ghoumari AM, Bielecki B, Steibel J, Boehm N, Liere P, Macklin WB, Kumar N, Habert R, Mhaouty-Kodja S, Tronche F, Sitruk-Ware R, Schumacher M, Ghandour MS. The neural androgen receptor: a therapeutic target for myelin repair in chronic demyelination. Brain. 2013 Jan; 136(Pt 1):132-46.
Score: 0.082
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Hussain R, El-Etr M, Gaci O, Rakotomamonjy J, Macklin WB, Kumar N, Sitruk-Ware R, Schumacher M, Ghoumari AM. Progesterone and Nestorone facilitate axon remyelination: a role for progesterone receptors. Endocrinology. 2011 Oct; 152(10):3820-31.
Score: 0.075
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Wang C, Wu C, Popescu DC, Zhu J, Macklin WB, Miller RH, Wang Y. Longitudinal near-infrared imaging of myelination. J Neurosci. 2011 Feb 16; 31(7):2382-90.
Score: 0.072
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Wu C, Wang C, Popescu DC, Zhu W, Somoza EA, Zhu J, Condie AG, Flask CA, Miller RH, Macklin W, Wang Y. A novel PET marker for in vivo quantification of myelination. Bioorg Med Chem. 2010 Dec 15; 18(24):8592-9.
Score: 0.071
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Wang C, Popescu DC, Wu C, Zhu J, Macklin W, Wang Y. In situ fluorescence imaging of myelination. J Histochem Cytochem. 2010 Jul; 58(7):611-21.
Score: 0.068
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Narayanan SP, Flores AI, Wang F, Macklin WB. Akt signals through the mammalian target of rapamycin pathway to regulate CNS myelination. J Neurosci. 2009 May 27; 29(21):6860-70.
Score: 0.064
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Hu X, He W, Diaconu C, Tang X, Kidd GJ, Macklin WB, Trapp BD, Yan R. Genetic deletion of BACE1 in mice affects remyelination of sciatic nerves. FASEB J. 2008 Aug; 22(8):2970-80.
Score: 0.059
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Hu X, Hicks CW, He W, Wong P, Macklin WB, Trapp BD, Yan R. Bace1 modulates myelination in the central and peripheral nervous system. Nat Neurosci. 2006 Dec; 9(12):1520-5.
Score: 0.054
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Lee KK, de Repentigny Y, Saulnier R, Rippstein P, Macklin WB, Kothary R. Dominant-negative beta1 integrin mice have region-specific myelin defects accompanied by alterations in MAPK activity. Glia. 2006 Jun; 53(8):836-44.
Score: 0.052
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Gudz TI, Komuro H, Macklin WB. Glutamate stimulates oligodendrocyte progenitor migration mediated via an alphav integrin/myelin proteolipid protein complex. J Neurosci. 2006 Mar 01; 26(9):2458-66.
Score: 0.051
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Yin X, Baek RC, Kirschner DA, Peterson A, Fujii Y, Nave KA, Macklin WB, Trapp BD. Evolution of a neuroprotective function of central nervous system myelin. J Cell Biol. 2006 Jan 30; 172(3):469-78.
Score: 0.051
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Fewou SN, Büssow H, Schaeren-Wiemers N, Vanier MT, Macklin WB, Gieselmann V, Eckhardt M. Reversal of non-hydroxy:alpha-hydroxy galactosylceramide ratio and unstable myelin in transgenic mice overexpressing UDP-galactose:ceramide galactosyltransferase. J Neurochem. 2005 Jul; 94(2):469-81.
Score: 0.049
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Given KS, Acker EG, Macklin WB, Carlin D, Owens GP, Bennett JL. Complement inhibition rapidly blocks lesion extension and facilitates remyelination in neuromyelitis optica. Acta Neuropathol Commun. 2025 06 12; 13(1):129.
Score: 0.049
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Owens GP, Fellin TJ, Matschulat A, Salas V, Schaller KL, Given KS, Ritchie AM, Navarro A, Blauth K, Hughes EG, Macklin WB, Bennett JL. Pathogenic myelin-specific antibodies in multiple sclerosis target conformational proteolipid protein 1-anchored membrane domains. J Clin Invest. 2023 10 02; 133(19).
Score: 0.043
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Fox MA, Colello RJ, Macklin WB, Fuss B. Phosphodiesterase-Ialpha/autotaxin: a counteradhesive protein expressed by oligodendrocytes during onset of myelination. Mol Cell Neurosci. 2003 Jul; 23(3):507-19.
Score: 0.043
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Frazier AP, Mitchell DN, Given KS, Hunn G, Burch AM, Childs CR, Moreno-Garcia M, Corigilano MR, Quillinan N, Macklin WB, Herson PS, Dingman AL. Chronic changes in oligodendrocyte sub-populations after middle cerebral artery occlusion in neonatal mice. Glia. 2023 06; 71(6):1429-1450.
Score: 0.042
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Macklin WB, Oberfield E, Lees MB. Electroblot analysis of rat myelin proteolipid protein and basic protein during development. Dev Neurosci. 1983-1984; 6(3):161-8.
Score: 0.041
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Mendiola AS, Church KA, Cardona SM, Vanegas D, Garcia SA, Macklin W, Lira SA, Ransohoff RM, Kokovay E, Lin CA, Cardona AE. Defective fractalkine-CX3CR1 signaling aggravates neuroinflammation and affects recovery from cuprizone-induced demyelination. J Neurochem. 2022 09; 162(5):430-443.
Score: 0.039
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Khandker L, Jeffries MA, Chang YJ, Mather ML, Evangelou AV, Bourne JN, Tafreshi AK, Ornelas IM, Bozdagi-Gunal O, Macklin WB, Wood TL. Cholesterol biosynthesis defines oligodendrocyte precursor heterogeneity between brain and spinal cord. Cell Rep. 2022 03 01; 38(9):110423.
Score: 0.039
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George NM, Gentile Polese A, Merle L, Macklin WB, Restrepo D. Excitable Axonal Domains Adapt to Sensory Deprivation in the Olfactory System. J Neurosci. 2022 02 23; 42(8):1491-1509.
Score: 0.038
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Macklin WB, Braun PE, Lees MB. Electroblot analysis of the myelin proteolipid protein. J Neurosci Res. 1982; 7(1):1-10.
Score: 0.038
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McLane LE, Bourne JN, Evangelou AV, Khandker L, Macklin WB, Wood TL. Loss of Tuberous Sclerosis Complex1 in Adult Oligodendrocyte Progenitor Cells Enhances Axon Remyelination and Increases Myelin Thickness after a Focal Demyelination. J Neurosci. 2017 08 02; 37(31):7534-7546.
Score: 0.028
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Asotra K, Macklin WB. Developmental expression of protein kinase C isozymes in oligodendrocytes and their differential modulation by 4 beta-phorbol-12,13-dibutyrate. J Neurosci Res. 1994 Oct 15; 39(3):273-89.
Score: 0.023
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Yu M, Narayanan SP, Wang F, Morse E, Macklin WB, Peachey NS. Visual abnormalities associated with enhanced optic nerve myelination. Brain Res. 2011 Feb 16; 1374:36-42.
Score: 0.018
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Kumar S, Macklin WB, Gordon MN, Espinosa de los Monteros A, Cole R, Scully SA, de Vellis J. Transcriptional regulation studies of myelin-associated genes in myelin-deficient mutant rats. Dev Neurosci. 1990; 12(4-5):316-25.
Score: 0.017
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Zhao L, Tian D, Xia M, Macklin WB, Feng Y. Rescuing qkV dysmyelination by a single isoform of the selective RNA-binding protein QKI. J Neurosci. 2006 Nov 01; 26(44):11278-86.
Score: 0.013
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Gao L, Macklin W, Gerson J, Miller RH. Intrinsic and extrinsic inhibition of oligodendrocyte development by rat retina. Dev Biol. 2006 Feb 15; 290(2):277-86.
Score: 0.013
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Sherman DL, Tait S, Melrose S, Johnson R, Zonta B, Court FA, Macklin WB, Meek S, Smith AJ, Cottrell DF, Brophy PJ. Neurofascins are required to establish axonal domains for saltatory conduction. Neuron. 2005 Dec 08; 48(5):737-42.
Score: 0.013
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Macklin WB, Weill CL. Appearance of myelin proteins during development in the chick central nervous system. Dev Neurosci. 1985; 7(3):170-8.
Score: 0.012
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Baracskay KL, Duchala CS, Miller RH, Macklin WB, Trapp BD. Oligodendrogenesis is differentially regulated in gray and white matter of jimpy mice. J Neurosci Res. 2002 Dec 01; 70(5):645-54.
Score: 0.010
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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