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Connection

Philippa Marrack to CD4-Positive T-Lymphocytes

This is a "connection" page, showing publications Philippa Marrack has written about CD4-Positive T-Lymphocytes.

 
Connection Strength
 
 
 
4.198
 
  1. Brown AJ, White J, Shaw L, Gross J, Slabodkin A, Kushner E, Greiff V, Matsuda J, Gapin L, Scott-Browne J, Kappler J, Marrack P. MHC heterozygosity limits T cell receptor variability in CD4 T cells. Sci Immunol. 2024 07 12; 9(97):eado5295.
    View in: PubMed
    Score: 0.587
  2. McKee AS, Marrack P. Old and new adjuvants. Curr Opin Immunol. 2017 Aug; 47:44-51.
    View in: PubMed
    Score: 0.362
  3. McKee AS, Burchill MA, Munks MW, Jin L, Kappler JW, Friedman RS, Jacobelli J, Marrack P. Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):E1122-31.
    View in: PubMed
    Score: 0.267
  4. Marrack P, Kappler JW. Do MHCII-presented neoantigens drive type 1 diabetes and other autoimmune diseases? Cold Spring Harb Perspect Med. 2012 Sep 01; 2(9):a007765.
    View in: PubMed
    Score: 0.258
  5. MacLeod MK, Kappler JW, Marrack P. Memory CD4 T cells: generation, reactivation and re-assignment. Immunology. 2010 May; 130(1):10-5.
    View in: PubMed
    Score: 0.218
  6. MacLeod MK, Clambey ET, Kappler JW, Marrack P. CD4 memory T cells: what are they and what can they do? Semin Immunol. 2009 Apr; 21(2):53-61.
    View in: PubMed
    Score: 0.203
  7. MacLeod MK, McKee A, Crawford F, White J, Kappler J, Marrack P. CD4 memory T cells divide poorly in response to antigen because of their cytokine profile. Proc Natl Acad Sci U S A. 2008 Sep 23; 105(38):14521-6.
    View in: PubMed
    Score: 0.196
  8. Huseby ES, Kappler JW, Marrack P. Thymic selection stifles TCR reactivity with the main chain structure of MHC and forces interactions with the peptide side chains. Mol Immunol. 2008 Feb; 45(3):599-606.
    View in: PubMed
    Score: 0.188
  9. Robertson JM, MacLeod M, Marsden VS, Kappler JW, Marrack P. Not all CD4+ memory T cells are long lived. Immunol Rev. 2006 Jun; 211:49-57.
    View in: PubMed
    Score: 0.167
  10. Murakami M, Sakamoto A, Bender J, Kappler J, Marrack P. CD25+CD4+ T cells contribute to the control of memory CD8+ T cells. Proc Natl Acad Sci U S A. 2002 Jun 25; 99(13):8832-7.
    View in: PubMed
    Score: 0.127
  11. Reed B, Crawford F, Hill RC, Jin N, White J, Krovi SH, Marrack P, Hansen K, Kappler JW. Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation. J Exp Med. 2021 02 01; 218(2).
    View in: PubMed
    Score: 0.116
  12. Gray JI, Al-Khabouri S, Morton F, Clambey ET, Gapin L, Matsuda JL, Kappler JW, Marrack P, Garside P, Otto TD, MacLeod MKL. Tolerance induction in memory CD4 T cells is partial and reversible. Immunology. 2021 01; 162(1):68-83.
    View in: PubMed
    Score: 0.114
  13. Bender J, Mitchell T, Kappler J, Marrack P. CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection. J Exp Med. 1999 Aug 02; 190(3):367-74.
    View in: PubMed
    Score: 0.104
  14. Wang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, Dai S. How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol. 2019 04 05; 4(34).
    View in: PubMed
    Score: 0.102
  15. Ignatowicz L, Rees W, Pacholczyk R, Ignatowicz H, Kushnir E, Kappler J, Marrack P. T cells can be activated by peptides that are unrelated in sequence to their selecting peptide. Immunity. 1997 Aug; 7(2):179-86.
    View in: PubMed
    Score: 0.091
  16. Ignatowicz L, Kappler J, Parker DC, Marrack P. The responses of mature T cells are not necessarily antagonized by their positively selecting peptide. J Immunol. 1996 Sep 01; 157(5):1827-31.
    View in: PubMed
    Score: 0.085
  17. Noges LE, White J, Cambier JC, Kappler JW, Marrack P. Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines. J Immunol. 2016 08 15; 197(4):1221-30.
    View in: PubMed
    Score: 0.084
  18. Clayton GM, Wang Y, Crawford F, Novikov A, Wimberly BT, Kieft JS, Falta MT, Bowerman NA, Marrack P, Fontenot AP, Dai S, Kappler JW. Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell. 2014 Jul 03; 158(1):132-42.
    View in: PubMed
    Score: 0.073
  19. David A, Crawford F, Garside P, Kappler JW, Marrack P, MacLeod M. Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation. Proc Natl Acad Sci U S A. 2014 May 27; 111(21):7735-40.
    View in: PubMed
    Score: 0.073
  20. Falta MT, Pinilla C, Mack DG, Tinega AN, Crawford F, Giulianotti M, Santos R, Clayton GM, Wang Y, Zhang X, Maier LA, Marrack P, Kappler JW, Fontenot AP. Identification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium disease. J Exp Med. 2013 Jul 01; 210(7):1403-18.
    View in: PubMed
    Score: 0.068
  21. Marrack P, Hugo P, McCormack J, Kappler J. Death and T cells. Immunol Rev. 1993 Jun; 133:119-29.
    View in: PubMed
    Score: 0.068
  22. Crawford F, Stadinski B, Jin N, Michels A, Nakayama M, Pratt P, Marrack P, Eisenbarth G, Kappler JW. Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse. Proc Natl Acad Sci U S A. 2011 Oct 04; 108(40):16729-34.
    View in: PubMed
    Score: 0.060
  23. MacLeod MK, David A, McKee AS, Crawford F, Kappler JW, Marrack P. Memory CD4 T cells that express CXCR5 provide accelerated help to B cells. J Immunol. 2011 Mar 01; 186(5):2889-96.
    View in: PubMed
    Score: 0.058
  24. Stadinski BD, Zhang L, Crawford F, Marrack P, Eisenbarth GS, Kappler JW. Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register. Proc Natl Acad Sci U S A. 2010 Jun 15; 107(24):10978-83.
    View in: PubMed
    Score: 0.055
  25. McKee AS, MacLeod MK, Kappler JW, Marrack P. Immune mechanisms of protection: can adjuvants rise to the challenge? BMC Biol. 2010 Apr 12; 8:37.
    View in: PubMed
    Score: 0.055
  26. McKee AS, MacLeod M, White J, Crawford F, Kappler JW, Marrack P. Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses. Int Immunol. 2008 May; 20(5):659-69.
    View in: PubMed
    Score: 0.047
  27. Khiong K, Murakami M, Kitabayashi C, Ueda N, Sawa S, Sakamoto A, Kotzin BL, Rozzo SJ, Ishihara K, Verella-Garcia M, Kappler J, Marrack P, Hirano T. Homeostatically proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model. J Clin Invest. 2007 May; 117(5):1270-81.
    View in: PubMed
    Score: 0.045
  28. Falta MT, Fontenot AP, Rosloniec EF, Crawford F, Roark CL, Bill J, Marrack P, Kappler J, Kotzin BL. Class II major histocompatibility complex-peptide tetramer staining in relation to functional avidity and T cell receptor diversity in the mouse CD4(+) T cell response to a rheumatoid arthritis-associated antigen. Arthritis Rheum. 2005 Jun; 52(6):1885-96.
    View in: PubMed
    Score: 0.039
  29. Myrick C, DiGuisto R, DeWolfe J, Bowen E, Kappler J, Marrack P, Wakeland EK. Linkage analysis of variations in CD4:CD8 T cell subsets between C57BL/6 and DBA/2. Genes Immun. 2002 May; 3(3):144-50.
    View in: PubMed
    Score: 0.032
  30. Meyer AL, Trollmo C, Crawford F, Marrack P, Steere AC, Huber BT, Kappler J, Hafler DA. Direct enumeration of Borrelia-reactive CD4 T cells ex vivo by using MHC class II tetramers. Proc Natl Acad Sci U S A. 2000 Oct 10; 97(21):11433-8.
    View in: PubMed
    Score: 0.028
  31. Kotzin BL, Falta MT, Crawford F, Rosloniec EF, Bill J, Marrack P, Kappler J. Use of soluble peptide-DR4 tetramers to detect synovial T cells specific for cartilage antigens in patients with rheumatoid arthritis. Proc Natl Acad Sci U S A. 2000 Jan 04; 97(1):291-6.
    View in: PubMed
    Score: 0.027
  32. Rees W, Bender J, Teague TK, Kedl RM, Crawford F, Marrack P, Kappler J. An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro. Proc Natl Acad Sci U S A. 1999 Aug 17; 96(17):9781-6.
    View in: PubMed
    Score: 0.026
  33. Mitchell T, Kappler J, Marrack P. Bystander virus infection prolongs activated T cell survival. J Immunol. 1999 Apr 15; 162(8):4527-35.
    View in: PubMed
    Score: 0.026
  34. Wang Y, Sosinowski T, Novikov A, Crawford F, Neau DB, Yang J, Kwok WW, Marrack P, Kappler JW, Dai S. C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes. Proc Natl Acad Sci U S A. 2018 01 02; 115(1):162-167.
    View in: PubMed
    Score: 0.023
  35. Ignatowicz L, Kappler J, Marrack P. The repertoire of T cells shaped by a single MHC/peptide ligand. Cell. 1996 Feb 23; 84(4):521-9.
    View in: PubMed
    Score: 0.021
  36. Mack DG, Falta MT, McKee AS, Martin AK, Simonian PL, Crawford F, Gordon T, Mercer RR, Hoover MD, Marrack P, Kappler JW, Tuder RM, Fontenot AP. Regulatory T cells modulate granulomatous inflammation in an HLA-DP2 transgenic murine model of beryllium-induced disease. Proc Natl Acad Sci U S A. 2014 Jun 10; 111(23):8553-8.
    View in: PubMed
    Score: 0.018
  37. Bedel R, Matsuda JL, Brigl M, White J, Kappler J, Marrack P, Gapin L. Lower TCR repertoire diversity in Traj18-deficient mice. Nat Immunol. 2012 Jul 19; 13(8):705-6.
    View in: PubMed
    Score: 0.016
  38. Ignatowicz L, Kappler J, Marrack P. The effects of chronic infection with a superantigen-producing virus. J Exp Med. 1992 Apr 01; 175(4):917-23.
    View in: PubMed
    Score: 0.016
  39. Choi Y, Kappler JW, Marrack P. A superantigen encoded in the open reading frame of the 3' long terminal repeat of mouse mammary tumour virus. Nature. 1991 Mar 21; 350(6315):203-7.
    View in: PubMed
    Score: 0.015
  40. Blackman M, Kappler J, Marrack P. The role of the T cell receptor in positive and negative selection of developing T cells. Science. 1990 Jun 15; 248(4961):1335-41.
    View in: PubMed
    Score: 0.014
  41. Blackman MA, Burgert HG, Gerhard-Burgert H, Woodland DL, Palmer E, Kappler JW, Marrack P. A role for clonal inactivation in T cell tolerance to Mls-1a. Nature. 1990 Jun 07; 345(6275):540-2.
    View in: PubMed
    Score: 0.014
  42. Dai S, Murphy GA, Crawford F, Mack DG, Falta MT, Marrack P, Kappler JW, Fontenot AP. Crystal structure of HLA-DP2 and implications for chronic beryllium disease. Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7425-30.
    View in: PubMed
    Score: 0.014
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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