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Connection

Dennis Roop to Keratins

This is a "connection" page, showing publications Dennis Roop has written about Keratins.

 
Connection Strength
 
 
 
7.030
 
  1. Chen J, Roop DR. Genetically engineered mouse models for skin research: taking the next step. J Dermatol Sci. 2008 Oct; 52(1):1-12.
    View in: PubMed
    Score: 0.290
  2. Chen J, Roop DR. Mouse models in preclinical studies for pachyonychia congenita. J Investig Dermatol Symp Proc. 2005 Oct; 10(1):37-46.
    View in: PubMed
    Score: 0.241
  3. Koch PJ, Roop DR. The role of keratins in epidermal development and homeostasis--going beyond the obvious. J Invest Dermatol. 2004 Nov; 123(5):x-xi.
    View in: PubMed
    Score: 0.226
  4. Arin MJ, Longley MA, Wang XJ, Roop DR. Focal activation of a mutant allele defines the role of stem cells in mosaic skin disorders. J Cell Biol. 2001 Feb 05; 152(3):645-9.
    View in: PubMed
    Score: 0.175
  5. Cao T, Longley MA, Wang XJ, Roop DR. An inducible mouse model for epidermolysis bullosa simplex: implications for gene therapy. J Cell Biol. 2001 Feb 05; 152(3):651-6.
    View in: PubMed
    Score: 0.175
  6. Wojcik SM, Bundman DS, Roop DR. Delayed wound healing in keratin 6a knockout mice. Mol Cell Biol. 2000 Jul; 20(14):5248-55.
    View in: PubMed
    Score: 0.168
  7. Suga Y, Arin MJ, Scott G, Goldsmith LA, Magro CM, Baden LA, Baden HP, Roop DR. Hot spot mutations in keratin 2e suggest a correlation between genotype and phenotype in patients with ichthyosis bullosa of Siemens. Exp Dermatol. 2000 Feb; 9(1):11-5.
    View in: PubMed
    Score: 0.163
  8. Arin MJ, Longley MA, Epstein EH, Rothnagel JA, Roop DR. Identification of a novel mutation in keratin 1 in a family with epidermolytic hyperkeratosis. Exp Dermatol. 2000 Feb; 9(1):16-9.
    View in: PubMed
    Score: 0.163
  9. Wojcik SM, Imakado S, Seki T, Longley MA, Petherbridge L, Bundman DS, Bickenbach JR, Rothnagel JA, Roop DR. Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle. Differentiation. 1999 Oct; 65(2):97-112.
    View in: PubMed
    Score: 0.159
  10. Rothnagel JA, Seki T, Ogo M, Longley MA, Wojcik SM, Bundman DS, Bickenbach JR, Roop DR. The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis. Differentiation. 1999 Oct; 65(2):119-30.
    View in: PubMed
    Score: 0.159
  11. Arin MJ, Longley MA, Anton-Lamprecht I, Kurze G, Huber M, Hohl D, Rothnagel JA, Roop DR. A novel substitution in keratin 10 in epidermolytic hyperkeratosis. J Invest Dermatol. 1999 Apr; 112(4):506-8.
    View in: PubMed
    Score: 0.154
  12. Lin MT, Levy ML, Bowden PE, Magro C, Baden L, Baden HP, Roop DR. Identification of sporadic mutations in the helix initiation motif of keratin 6 in two pachyonychia congenita patients: further evidence for a mutational hot spot. Exp Dermatol. 1999 Apr; 8(2):115-9.
    View in: PubMed
    Score: 0.154
  13. Arin MJ, Longley MA, K?ster W, Huber M, Hohl D, Rothnagel JA, Roop DR. An asparagine to threonine substitution in the 1A domain of keratin 1: a novel mutation that causes epidermolytic hyperkeratosis. Exp Dermatol. 1999 Apr; 8(2):124-7.
    View in: PubMed
    Score: 0.154
  14. Arin MJ, Longley MA, Epstein EH, Scott G, Goldsmith LA, Rothnagel JA, Roop DR. A novel mutation in the 1A domain of keratin 2e in ichthyosis bullosa of Siemens. J Invest Dermatol. 1999 Mar; 112(3):380-2.
    View in: PubMed
    Score: 0.153
  15. Suga Y, Duncan KO, Heald PW, Roop DR. A novel helix termination mutation in keratin 10 in annular epidermolytic ichthyosis, a variant of bullous congenital ichthyosiform erythroderma. J Invest Dermatol. 1998 Dec; 111(6):1220-3.
    View in: PubMed
    Score: 0.150
  16. Rothnagel JA, Lin MT, Longley MA, Holder RA, Hazen PG, Levy ML, Roop DR. Prenatal diagnosis for keratin mutations to exclude transmission of epidermolytic hyperkeratosis. Prenat Diagn. 1998 Aug; 18(8):826-30.
    View in: PubMed
    Score: 0.147
  17. Joh GY, Traupe H, Metze D, Nashan D, Huber M, Hohl D, Longley MA, Rothnagel JA, Roop DR. A novel dinucleotide mutation in keratin 10 in the annular epidermolytic ichthyosis variant of bullous congenital ichthyosiform erythroderma. J Invest Dermatol. 1997 Mar; 108(3):357-61.
    View in: PubMed
    Score: 0.133
  18. Bickenbach JR, Longley MA, Bundman DS, Dominey AM, Bowden PE, Rothnagel JA, Roop DR. A transgenic mouse model that recapitulates the clinical features of both neonatal and adult forms of the skin disease epidermolytic hyperkeratosis. Differentiation. 1996 Dec; 61(2):129-39.
    View in: PubMed
    Score: 0.131
  19. Kumar V, Bouameur JE, B?r J, Rice RH, Hornig-Do HT, Roop DR, Schwarz N, Brodesser S, Thiering S, Leube RE, Wiesner RJ, Vijayaraj P, Brazel CB, Heller S, Binder H, L?ffler-Wirth H, Seibel P, Magin TM. A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 07; 211(5):1057-75.
    View in: PubMed
    Score: 0.122
  20. Rothnagel JA, Wojcik S, Liefer KM, Dominey AM, Huber M, Hohl D, Roop DR. Mutations in the 1A domain of keratin 9 in patients with epidermolytic palmoplantar keratoderma. J Invest Dermatol. 1995 Mar; 104(3):430-3.
    View in: PubMed
    Score: 0.116
  21. Rothnagel JA, Traupe H, Wojcik S, Huber M, Hohl D, Pittelkow MR, Saeki H, Ishibashi Y, Roop DR. Mutations in the rod domain of keratin 2e in patients with ichthyosis bullosa of Siemens. Nat Genet. 1994 Aug; 7(4):485-90.
    View in: PubMed
    Score: 0.111
  22. Rothnagel JA, Longley MA, Holder RA, Bundman DS, Seki T, Bickenbach JR, Roop DR. Genetic disorders of keratin: are scarring alopecias a sub-set? J Dermatol Sci. 1994 Jul; 7 Suppl:S164-9.
    View in: PubMed
    Score: 0.111
  23. Lu B, Rothnagel JA, Longley MA, Tsai SY, Roop DR. Differentiation-specific expression of human keratin 1 is mediated by a composite AP-1/steroid hormone element. J Biol Chem. 1994 Mar 11; 269(10):7443-9.
    View in: PubMed
    Score: 0.108
  24. van Steensel MAM, Coulombe PA, Kaspar RL, Milstone LM, McLean IWH, Roop DR, Smith FJD, Sprecher E, Schwartz ME. Report of the 10th Annual International Pachyonychia Congenita Consortium Meeting. J Invest Dermatol. 2014 Mar; 134(3):588-591.
    View in: PubMed
    Score: 0.108
  25. Rothnagel JA, Fisher MP, Axtell SM, Pittelkow MR, Anton-Lamprecht I, Huber M, Hohl D, Roop DR. A mutational hot spot in keratin 10 (KRT 10) in patients with epidermolytic hyperkeratosis. Hum Mol Genet. 1993 Dec; 2(12):2147-50.
    View in: PubMed
    Score: 0.106
  26. Greenhalgh DA, Quintanilla MI, Orengo CC, Barber JL, Eckhardt JN, Rothnagel JA, Roop DR. Cooperation between v-fos and v-rasHA induces autonomous papillomas in transgenic epidermis but not malignant conversion. Cancer Res. 1993 Nov 01; 53(21):5071-5.
    View in: PubMed
    Score: 0.106
  27. Rothnagel JA, Greenhalgh DA, Wang XJ, Sellheyer K, Bickenbach JR, Dominey AM, Roop DR. Transgenic models of skin diseases. Arch Dermatol. 1993 Nov; 129(11):1430-6.
    View in: PubMed
    Score: 0.106
  28. Rothnagel JA, Greenhalgh DA, Gagne TA, Longley MA, Roop DR. Identification of a calcium-inducible, epidermal-specific regulatory element in the 3'-flanking region of the human keratin 1 gene. J Invest Dermatol. 1993 Oct; 101(4):506-13.
    View in: PubMed
    Score: 0.105
  29. Rothnagel JA, Dominey AM, Dempsey LD, Longley MA, Greenhalgh DA, Gagne TA, Huber M, Frenk E, Hohl D, Roop DR. Mutations in the rod domains of keratins 1 and 10 in epidermolytic hyperkeratosis. Science. 1992 Aug 21; 257(5073):1128-30.
    View in: PubMed
    Score: 0.097
  30. Rosenthal DS, Steinert PM, Chung S, Huff CA, Johnson J, Yuspa SH, Roop DR. A human epidermal differentiation-specific keratin gene is regulated by calcium but not negative modulators of differentiation in transgenic mouse keratinocytes. Cell Growth Differ. 1991 Feb; 2(2):107-13.
    View in: PubMed
    Score: 0.087
  31. Smith GH, Mehrel T, Roop DR. Differential keratin gene expression in developing, differentiating, preneoplastic, and neoplastic mouse mammary epithelium. Cell Growth Differ. 1990 Apr; 1(4):161-70.
    View in: PubMed
    Score: 0.082
  32. De Luca LM, Huang FL, Roop DR. Retinoids and control of epithelial differentiation and keratin biosynthesis in hamster trachea. Methods Enzymol. 1990; 190:91-100.
    View in: PubMed
    Score: 0.081
  33. Yuspa SH, Kilkenny AE, Steinert PM, Roop DR. Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro. J Cell Biol. 1989 Sep; 109(3):1207-17.
    View in: PubMed
    Score: 0.079
  34. Roop DR, Mehrel T, Krieg TM, Nakazawa H, Cheng CK, Yuspa SH. Keratin expression in mouse epidermal tumors. Carcinog Compr Surv. 1989; 11:257-71.
    View in: PubMed
    Score: 0.076
  35. Roop DR, Krieg TM, Mehrel T, Cheng CK, Yuspa SH. Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis. Cancer Res. 1988 Jun 01; 48(11):3245-52.
    View in: PubMed
    Score: 0.073
  36. Fisher C, Jones A, Roop DR. Abnormal expression and processing of keratins in pupoid fetus (pf/pf) and repeated epilation (Er/Er) mutant mice. J Cell Biol. 1987 Oct; 105(4):1807-19.
    View in: PubMed
    Score: 0.069
  37. Roop DR. Regulation of keratin gene expression during differentiation of epidermal and vaginal epithelial cells. Curr Top Dev Biol. 1987; 22:195-207.
    View in: PubMed
    Score: 0.066
  38. Roop DR, Huitfeldt H, Kilkenny A, Yuspa SH. Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins. Differentiation. 1987; 35(2):143-50.
    View in: PubMed
    Score: 0.066
  39. Grimm SL, Bu W, Longley MA, Roop DR, Li Y, Rosen JM. Keratin 6 is not essential for mammary gland development. Breast Cancer Res. 2006; 8(3):R29.
    View in: PubMed
    Score: 0.063
  40. Toftgard R, Yuspa SH, Roop DR. Keratin gene expression in mouse skin tumors and in mouse skin treated with 12-O-tetradecanoylphorbol-13-acetate. Cancer Res. 1985 Nov; 45(11 Pt 2):5845-50.
    View in: PubMed
    Score: 0.061
  41. Koster MI, Roop DR. Asymmetric cell division in skin development: a new look at an old observation. Dev Cell. 2005 Oct; 9(4):444-6.
    View in: PubMed
    Score: 0.060
  42. Steinert PM, Parry DA, Idler WW, Johnson LD, Steven AC, Roop DR. Amino acid sequences of mouse and human epidermal type II keratins of Mr 67,000 provide a systematic basis for the structural and functional diversity of the end domains of keratin intermediate filament subunits. J Biol Chem. 1985 Jun 10; 260(11):7142-9.
    View in: PubMed
    Score: 0.059
  43. Krieg TM, Schafer MP, Cheng CK, Filpula D, Flaherty P, Steinert PM, Roop DR. Organization of a type I keratin gene. Evidence for evolution of intermediate filaments from a common ancestral gene. J Biol Chem. 1985 May 25; 260(10):5867-70.
    View in: PubMed
    Score: 0.059
  44. Roop DR, Cheng CK, Toftgard R, Stanley JR, Steinert PM, Yuspa SH. The use of cDNA clones and monospecific antibodies as probes to monitor keratin gene expression. Ann N Y Acad Sci. 1985; 455:426-35.
    View in: PubMed
    Score: 0.057
  45. Steinert PM, Idler WW, Zhou XM, Johnson LD, Parry DA, Steven AC, Roop DR. Structural and functional implications of amino acid sequences of keratin intermediate filament subunits. Ann N Y Acad Sci. 1985; 455:451-61.
    View in: PubMed
    Score: 0.057
  46. Steinert PM, Parry DA, Racoosin EL, Idler WW, Steven AC, Trus BL, Roop DR. The complete cDNA and deduced amino acid sequence of a type II mouse epidermal keratin of 60,000 Da: analysis of sequence differences between type I and type II keratins. Proc Natl Acad Sci U S A. 1984 Sep; 81(18):5709-13.
    View in: PubMed
    Score: 0.056
  47. Caulin C, Nguyen T, Longley MA, Zhou Z, Wang XJ, Roop DR. Inducible activation of oncogenic K-ras results in tumor formation in the oral cavity. Cancer Res. 2004 Aug 01; 64(15):5054-8.
    View in: PubMed
    Score: 0.056
  48. Roop DR, Cheng CK, Titterington L, Meyers CA, Stanley JR, Steinert PM, Yuspa SH. Synthetic peptides corresponding to keratin subunits elicit highly specific antibodies. J Biol Chem. 1984 Jul 10; 259(13):8037-40.
    View in: PubMed
    Score: 0.055
  49. Arin MJ, Roop DR. Inducible mouse models for inherited skin diseases: implications for skin gene therapy. Cells Tissues Organs. 2004; 177(3):160-8.
    View in: PubMed
    Score: 0.053
  50. Roop DR, Hawley-Nelson P, Cheng CK, Yuspa SH. Expression of keratin genes in mouse epidermis and normal and malignantly transformed epidermal cells in culture. J Invest Dermatol. 1983 Jul; 81(1 Suppl):144s-9s.
    View in: PubMed
    Score: 0.052
  51. Steinert PM, Steven AC, Roop DR. Structural features of epidermal keratin filaments reassembled in vitro. J Invest Dermatol. 1983 Jul; 81(1 Suppl):86s-90s.
    View in: PubMed
    Score: 0.052
  52. Roop DR, Hawley-Nelson P, Cheng CK, Yuspa SH. Keratin gene expression in mouse epidermis and cultured epidermal cells. Proc Natl Acad Sci U S A. 1983 Feb; 80(3):716-20.
    View in: PubMed
    Score: 0.050
  53. Cao T, He W, Roop DR, Wang XJ. K14-GLp65 transactivator induces transgene expression in embryonic epidermis. Genesis. 2002 Feb; 32(2):189-90.
    View in: PubMed
    Score: 0.047
  54. Zhou Z, Wang D, Wang XJ, Roop DR. In utero activation of K5.CrePR1 induces gene deletion. Genesis. 2002 Feb; 32(2):191-2.
    View in: PubMed
    Score: 0.047
  55. Wang XJ, Greenhalgh DA, Donehower LA, Roop DR. Cooperation between Ha-ras and fos or transforming growth factor alpha overcomes a paradoxic tumor-inhibitory effect of p53 loss in transgenic mouse epidermis. Mol Carcinog. 2000 Oct; 29(2):67-75.
    View in: PubMed
    Score: 0.043
  56. Berton TR, Wang XJ, Zhou Z, Kellendonk C, Sch?tz G, Tsai S, Roop DR. Characterization of an inducible, epidermal-specific knockout system: differential expression of lacZ in different Cre reporter mouse strains. Genesis. 2000 Feb; 26(2):160-1.
    View in: PubMed
    Score: 0.041
  57. Waikel RL, Wang XJ, Roop DR. Targeted expression of c-Myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis. Oncogene. 1999 Aug 26; 18(34):4870-8.
    View in: PubMed
    Score: 0.040
  58. Wang XJ, Greenhalgh DA, Jiang A, He D, Zhong L, Medina D, Brinkley BR, Roop DR. Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis. Oncogene. 1998 Jul 09; 17(1):35-45.
    View in: PubMed
    Score: 0.037
  59. Rodr?guez-Villanueva J, Greenhalgh D, Wang XJ, Bundman D, Cho S, Delehedde M, Roop D, McDonnell TJ. Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation. Oncogene. 1998 Feb 19; 16(7):853-63.
    View in: PubMed
    Score: 0.036
  60. Liu Y, Snedecor ER, Zhang X, Xu Y, Huang L, Jones EC, Zhang L, Clark RA, Roop DR, Qin C, Chen J. Correction of Hair Shaft Defects through Allele-Specific Silencing of Mutant Krt75. J Invest Dermatol. 2016 Jan; 136(1):45-51.
    View in: PubMed
    Score: 0.031
  61. Rothnagel JA, Roop DR. Hair follicle companion layer: reacquainting an old friend. J Invest Dermatol. 1995 May; 104(5 Suppl):42S-43S.
    View in: PubMed
    Score: 0.029
  62. Greenhalgh DA, Wang XJ, Eckhardt JN, Roop DR. 12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mice expressing epidermal-targeted v-fos induces rasHA-activated papillomas and carcinomas without p53 mutation: association of v-fos expression with promotion and tumor autonomy. Cell Growth Differ. 1995 May; 6(5):579-86.
    View in: PubMed
    Score: 0.029
  63. Roop D. Defects in the barrier. Science. 1995 Jan 27; 267(5197):474-5.
    View in: PubMed
    Score: 0.029
  64. Wang XJ, Greenhalgh DA, Lu XR, Bickenbach JR, Roop DR. TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas. Oncogene. 1995 Jan 19; 10(2):279-89.
    View in: PubMed
    Score: 0.029
  65. Ishida-Yamamoto A, Iizuka H, Manabe M, O'Guin WM, Hohl D, Kartasova T, Kuroki T, Roop DR, Eady RA. Altered distribution of keratinization markers in epidermolytic hyperkeratosis. Arch Dermatol Res. 1995; 287(8):705-11.
    View in: PubMed
    Score: 0.029
  66. Heyden A, L?tzow-Holm C, Clausen OP, Thrane EV, Brandtzaeg P, Roop DR, Yuspa SH, Huitfeldt HS. Application of cantharidin or 12-O-tetradecanoylphorbol-13-acetate on mouse epidermis induces a cell population shift that causes altered keratin distribution. Differentiation. 1994 Sep; 57(3):187-93.
    View in: PubMed
    Score: 0.028
  67. Greenhalgh DA, Wang XJ, Rothnagel JA, Eckhardt JN, Quintanilla MI, Barber JL, Bundman DS, Longley MA, Schlegel R, Roop DR. Transgenic mice expressing targeted HPV-18 E6 and E7 oncogenes in the epidermis develop verrucous lesions and spontaneous, rasHa-activated papillomas. Cell Growth Differ. 1994 Jun; 5(6):667-75.
    View in: PubMed
    Score: 0.027
  68. Huber M, Scaletta C, Benathan M, Frenk E, Greenhalgh DA, Rothnagel JA, Roop DR, Hohl D. Abnormal keratin 1 and 10 cytoskeleton in cultured keratinocytes from epidermolytic hyperkeratosis caused by keratin 10 mutations. J Invest Dermatol. 1994 May; 102(5):691-4.
    View in: PubMed
    Score: 0.027
  69. Gimenez-Conti IB, Lynch M, Roop D, Bhowmik S, Majeski P, Conti CJ. Expression of keratins in mouse vaginal epithelium. Differentiation. 1994 May; 56(3):143-51.
    View in: PubMed
    Score: 0.027
  70. Sundberg JP, Erickson AA, Roop DR, Binder RL. Ornithine decarboxylase expression in cutaneous papillomas in SENCAR mice is associated with altered expression of keratins 1 and 10. Cancer Res. 1994 Mar 01; 54(5):1344-51.
    View in: PubMed
    Score: 0.027
  71. Rothnagel JA, Longley MA, Holder RA, K?ster W, Roop DR. Prenatal diagnosis of epidermolytic hyperkeratosis by direct gene sequencing. J Invest Dermatol. 1994 Jan; 102(1):13-6.
    View in: PubMed
    Score: 0.027
  72. Greenhalgh DA, Wang XJ, Dominey AM, Rothnagel JA, Roop DR. Development of transgenic mouse models of skin carcinogenesis: potential applications. Prog Clin Biol Res. 1994; 387:75-94.
    View in: PubMed
    Score: 0.027
  73. Greenhalgh DA, Rothnagel JA, Wang XJ, Quintanilla MI, Orengo CC, Gagne TA, Bundman DS, Longley MA, Fisher C, Roop DR. Hyperplasia, hyperkeratosis and benign tumor production in transgenic mice by a targeted v-fos oncogene suggest a role for fos in epidermal differentiation and neoplasia. Oncogene. 1993 Aug; 8(8):2145-57.
    View in: PubMed
    Score: 0.026
  74. Kartasova T, Roop DR, Holbrook KA, Yuspa SH. Mouse differentiation-specific keratins 1 and 10 require a preexisting keratin scaffold to form a filament network. J Cell Biol. 1993 Mar; 120(5):1251-61.
    View in: PubMed
    Score: 0.025
  75. Robles AI, Gimenez-Conti IB, Roop D, Slaga TJ, Conti CJ. Low frequency of codon 61 Ha-ras mutations and lack of keratin 13 expression in 7,12-dimethylbenz[a]-anthracene-induced hamster skin tumors. Mol Carcinog. 1993; 7(2):94-8.
    View in: PubMed
    Score: 0.025
  76. Greenhalgh DA, Rothnagel JA, Quintanilla MI, Orengo CC, Gagne TA, Bundman DS, Longley MA, Roop DR. Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v-Ha-ras oncogene. Mol Carcinog. 1993; 7(2):99-110.
    View in: PubMed
    Score: 0.025
  77. Blouin R, Blouin MJ, Royal I, Grenier A, Roop DR, Loranger A, Marceau N. Cytokeratin 14 expression in rat liver cells in culture and localization in vivo. Differentiation. 1992 Dec; 52(1):45-54.
    View in: PubMed
    Score: 0.025
  78. Yuspa SH, Kraemer KH, Dlugosz AA, Roop DR, Kulesz-Martin M, Bickenbach JR. Montagna Symposium 2011: 60th Anniversary--Advances in Science and Medicine Catalyzed by Pioneering Skin Research. J Invest Dermatol. 2012 May; 132(5):1317-20.
    View in: PubMed
    Score: 0.024
  79. Rosenthal DS, Griffiths CE, Yuspa SH, Roop DR, Voorhees JJ. Acute or chronic topical retinoic acid treatment of human skin in vivo alters the expression of epidermal transglutaminase, loricrin, involucrin, filaggrin, and keratins 6 and 13 but not keratins 1, 10, and 14. J Invest Dermatol. 1992 Mar; 98(3):343-50.
    View in: PubMed
    Score: 0.024
  80. Kartasova T, Roop DR, Yuspa SH. Relationship between the expression of differentiation-specific keratins 1 and 10 and cell proliferation in epidermal tumors. Mol Carcinog. 1992; 6(1):18-25.
    View in: PubMed
    Score: 0.023
  81. Huitfeldt HS, Heyden A, Clausen OP, Thrane EV, Roop D, Yuspa SH. Altered regulation of growth and expression of differentiation-associated keratins in benign mouse skin tumors. Carcinogenesis. 1991 Nov; 12(11):2063-7.
    View in: PubMed
    Score: 0.023
  82. Breitkreutz D, Boukamp P, Ryle CM, Stark HJ, Roop DR, Fusenig NE. Epidermal morphogenesis and keratin expression in c-Ha-ras-transfected tumorigenic clones of the human HaCaT cell line. Cancer Res. 1991 Aug 15; 51(16):4402-9.
    View in: PubMed
    Score: 0.023
  83. Gimenez-Conti I, Aldaz CM, Bianchi AB, Roop DR, Slaga TJ, Conti CJ. Early expression of type I K13 keratin in the progression of mouse skin papillomas. Carcinogenesis. 1990 Nov; 11(11):1995-9.
    View in: PubMed
    Score: 0.021
  84. Rothnagel JA, Longley MA, Bundman D, Greenhalgh DA, Dominey AM, Roop DR. Targeting gene expression to the epidermis of transgenic mice: potential applications to genetic skin disorders. J Invest Dermatol. 1990 Nov; 95(5 Suppl):59S-61S.
    View in: PubMed
    Score: 0.021
  85. Stark HJ, Breitkreutz D, Limat A, Ryle CM, Roop D, Leigh I, Fusenig N. Keratins 1 and 10 or homologues as regular constituents of inner root sheath and cuticle cells in the human hair follicle. Eur J Cell Biol. 1990 Aug; 52(2):359-72.
    View in: PubMed
    Score: 0.021
  86. Gimenez-Conti IB, Shin DM, Bianchi AB, Roop DR, Hong WK, Conti CJ, Slaga TJ. Changes in keratin expression during 7,12-dimethylbenz[a]anthracene-induced hamster cheek pouch carcinogenesis. Cancer Res. 1990 Jul 15; 50(14):4441-5.
    View in: PubMed
    Score: 0.021
  87. Cheng C, Kilkenny AE, Roop D, Yuspa SH. The v-ras oncogene inhibits the expression of differentiation markers and facilitates expression of cytokeratins 8 and 18 in mouse keratinocytes. Mol Carcinog. 1990; 3(6):363-73.
    View in: PubMed
    Score: 0.020
  88. Ryle CM, Breitkreutz D, Stark HJ, Leigh IM, Steinert PM, Roop D, Fusenig NE. Density-dependent modulation of synthesis of keratins 1 and 10 in the human keratinocyte line HACAT and in ras-transfected tumorigenic clones. Differentiation. 1989 Mar; 40(1):42-54.
    View in: PubMed
    Score: 0.019
  89. Luo W, Roop DR, Lau EC, Melrose RJ, Mostofi R, Stenman G, Snead ML. In situ hybridization analysis of keratin gene expression in human ameloblastomas. J Oral Pathol. 1988 Nov; 17(9-10):534-40.
    View in: PubMed
    Score: 0.019
  90. Zhou XM, Idler WW, Steven AC, Roop DR, Steinert PM. The complete sequence of the human intermediate filament chain keratin 10. Subdomainal divisions and model for folding of end domain sequences. J Biol Chem. 1988 Oct 25; 263(30):15584-9.
    View in: PubMed
    Score: 0.019
  91. Aldaz CM, Conti CJ, Larcher F, Trono D, Roop DR, Chesner J, Whitehead T, Slaga TJ. Sequential development of aneuploidy, keratin modifications, and gamma-glutamyltransferase expression in mouse skin papillomas. Cancer Res. 1988 Jun 01; 48(11):3253-7.
    View in: PubMed
    Score: 0.018
  92. Yuspa SH, Kilkenny A, Roop DR. Aberrant differentiation in mouse skin carcinogenesis. IARC Sci Publ. 1988; (92):3-10.
    View in: PubMed
    Score: 0.018
  93. Yuspa SH, Hennings H, Tucker RW, Jaken S, Kilkenny AE, Roop DR. Signal transduction for proliferation and differentiation in keratinocytes. Ann N Y Acad Sci. 1988; 548:191-6.
    View in: PubMed
    Score: 0.018
  94. Roop DR, Lowy DR, Tambourin PE, Strickland J, Harper JR, Balaschak M, Spangler EF, Yuspa SH. An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue. Nature. 1986 Oct 30-Nov 5; 323(6091):822-4.
    View in: PubMed
    Score: 0.016
  95. Huang FL, Roop DR, De Luca LM. Vitamin A deficiency and keratin biosynthesis in cultured hamster trachea. In Vitro Cell Dev Biol. 1986 Apr; 22(4):223-30.
    View in: PubMed
    Score: 0.016
  96. Steinert PM, Steven AC, Roop DR. The molecular biology of intermediate filaments. Cell. 1985 Sep; 42(2):411-20.
    View in: PubMed
    Score: 0.015
  97. Johnson LD, Idler WW, Zhou XM, Roop DR, Steinert PM. Structure of a gene for the human epidermal 67-kDa keratin. Proc Natl Acad Sci U S A. 1985 Apr; 82(7):1896-900.
    View in: PubMed
    Score: 0.015
  98. Xu X, Kawachi Y, Nakamura Y, Sakurai H, Hirota A, Banno T, Takahashi T, Roop DR, Otsuka F. Yin-yang 1 negatively regulates the differentiation-specific transcription of mouse loricrin gene in undifferentiated keratinocytes. J Invest Dermatol. 2004 Dec; 123(6):1120-6.
    View in: PubMed
    Score: 0.014
  99. Wakabayashi N, Itoh K, Wakabayashi J, Motohashi H, Noda S, Takahashi S, Imakado S, Kotsuji T, Otsuka F, Roop DR, Harada T, Engel JD, Yamamoto M. Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation. Nat Genet. 2003 Nov; 35(3):238-45.
    View in: PubMed
    Score: 0.013
  100. Steinert PM, Rice RH, Roop DR, Trus BL, Steven AC. Complete amino acid sequence of a mouse epidermal keratin subunit and implications for the structure of intermediate filaments. Nature. 1983 Apr 28; 302(5911):794-800.
    View in: PubMed
    Score: 0.013
  101. Klug DB, Carter C, Crouch E, Roop D, Conti CJ, Richie ER. Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment. Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20):11822-7.
    View in: PubMed
    Score: 0.009
  102. Kulesz-Martin MF, Lisafeld B, Paterson J, Driscoll D, Shudo K, Roop DR, Kisiel ND. Differentiation and tumor response to retinobenzoic acid RE-80 in a malignant conversion model. Cancer Detect Prev. 1995; 19(4):355-66.
    View in: PubMed
    Score: 0.007
  103. Brown LJ, Geesin JC, Rothnagel JA, Roop DR, Gordon JS. Retinoic acid suppression of loricrin expression in reconstituted human skin cultured at the liquid-air interface. J Invest Dermatol. 1994 Jun; 102(6):886-90.
    View in: PubMed
    Score: 0.007
  104. Sundberg JP, Roop DR, Dunstan R, Lavker R, Sun TT. Interaction between dermal papilla and bulge: the rhino mouse mutation as a model system. Ann N Y Acad Sci. 1991 Dec 26; 642:496-9.
    View in: PubMed
    Score: 0.006
  105. Sundberg JP, Hanson CA, Roop DR, Brown KS, Bedigian HG. Myoepitheliomas in inbred laboratory mice. Vet Pathol. 1991 Jul; 28(4):313-23.
    View in: PubMed
    Score: 0.006
  106. Rosenthal DS, Roop DR, Huff CA, Weiss JS, Ellis CN, Hamilton T, Voorhees JJ, Yuspa SH. Changes in photo-aged human skin following topical application of all-trans retinoic acid. J Invest Dermatol. 1990 Nov; 95(5):510-5.
    View in: PubMed
    Score: 0.005
  107. Rogers GE, Martinet N, Steinert P, Wynn P, Roop D, Kilkenny A, Morgan D, Yuspa SH. A procedure for the culture of hair follicles as functionally intact organoids. Clin Dermatol. 1988 Oct-Dec; 6(4):36-41.
    View in: PubMed
    Score: 0.005
  108. Hawley-Nelson P, Roop DR, Cheng CK, Krieg TM, Yuspa SH. Molecular cloning of mouse epidermal cystatin A and detection of regulated expression in differentiation and tumorigenesis. Mol Carcinog. 1988; 1(3):202-11.
    View in: PubMed
    Score: 0.004
  109. Harper JR, Roop DR, Yuspa SH. Transfection of the EJ rasHa gene into keratinocytes derived from carcinogen-induced mouse papillomas causes malignant progression. Mol Cell Biol. 1986 Sep; 6(9):3144-9.
    View in: PubMed
    Score: 0.004
  110. De Luca LM, Roop D, Huang FL. Vitamin A: a key nutrient for the maintenance of epithelial differentiation. Acta Vitaminol Enzymol. 1985; 7 Suppl:13-20.
    View in: PubMed
    Score: 0.004
Connection Strength

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