Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Connection

Sharon Grady to Mice

This is a "connection" page, showing publications Sharon Grady has written about Mice.

 
Connection Strength
 
 
 
0.459
 
  1. Wageman CR, Marks MJ, Grady SR. Effectiveness of nicotinic agonists as desensitizers at presynaptic a4ß2- and a4a5ß2-nicotinic acetylcholine receptors. Nicotine Tob Res. 2014 Mar; 16(3):297-305.
    View in: PubMed
    Score: 0.029
  2. Quik M, Campos C, Grady SR. Multiple CNS nicotinic receptors mediate L-dopa-induced dyskinesias: studies with parkinsonian nicotinic receptor knockout mice. Biochem Pharmacol. 2013 Oct 15; 86(8):1153-62.
    View in: PubMed
    Score: 0.029
  3. Quik M, Park KM, Hrachova M, Mallela A, Huang LZ, McIntosh JM, Grady SR. Role for a6 nicotinic receptors in l-dopa-induced dyskinesias in parkinsonian mice. Neuropharmacology. 2012 Sep; 63(3):450-9.
    View in: PubMed
    Score: 0.027
  4. Ortiz NC, O'Neill HC, Marks MJ, Grady SR. Varenicline blocks ß2*-nAChR-mediated response and activates ß4*-nAChR-mediated responses in mice in vivo. Nicotine Tob Res. 2012 Jun; 14(6):711-9.
    View in: PubMed
    Score: 0.026
  5. Grady SR, Wageman CR, Patzlaff NE, Marks MJ. Low concentrations of nicotine differentially desensitize nicotinic acetylcholine receptors that include a5 or a6 subunits and that mediate synaptosomal neurotransmitter release. Neuropharmacology. 2012 Apr; 62(5-6):1935-43.
    View in: PubMed
    Score: 0.026
  6. Grady SR, Drenan RM, Breining SR, Yohannes D, Wageman CR, Fedorov NB, McKinney S, Whiteaker P, Bencherif M, Lester HA, Marks MJ. Structural differences determine the relative selectivity of nicotinic compounds for native alpha 4 beta 2*-, alpha 6 beta 2*-, alpha 3 beta 4*- and alpha 7-nicotine acetylcholine receptors. Neuropharmacology. 2010 Jun; 58(7):1054-66.
    View in: PubMed
    Score: 0.023
  7. Grady SR, Salminen O, McIntosh JM, Marks MJ, Collins AC. Mouse striatal dopamine nerve terminals express alpha4alpha5beta2 and two stoichiometric forms of alpha4beta2*-nicotinic acetylcholine receptors. J Mol Neurosci. 2010 Jan; 40(1-2):91-5.
    View in: PubMed
    Score: 0.022
  8. Grady SR, Moretti M, Zoli M, Marks MJ, Zanardi A, Pucci L, Clementi F, Gotti C. Rodent habenulo-interpeduncular pathway expresses a large variety of uncommon nAChR subtypes, but only the alpha3beta4* and alpha3beta3beta4* subtypes mediate acetylcholine release. J Neurosci. 2009 Feb 18; 29(7):2272-82.
    View in: PubMed
    Score: 0.021
  9. Grady SR, Salminen O, Laverty DC, Whiteaker P, McIntosh JM, Collins AC, Marks MJ. The subtypes of nicotinic acetylcholine receptors on dopaminergic terminals of mouse striatum. Biochem Pharmacol. 2007 Oct 15; 74(8):1235-46.
    View in: PubMed
    Score: 0.019
  10. Salminen O, Drapeau JA, McIntosh JM, Collins AC, Marks MJ, Grady SR. Pharmacology of alpha-conotoxin MII-sensitive subtypes of nicotinic acetylcholine receptors isolated by breeding of null mutant mice. Mol Pharmacol. 2007 Jun; 71(6):1563-71.
    View in: PubMed
    Score: 0.019
  11. Salminen O, Murphy KL, McIntosh JM, Drago J, Marks MJ, Collins AC, Grady SR. Subunit composition and pharmacology of two classes of striatal presynaptic nicotinic acetylcholine receptors mediating dopamine release in mice. Mol Pharmacol. 2004 Jun; 65(6):1526-35.
    View in: PubMed
    Score: 0.015
  12. Quik M, Sum JD, Whiteaker P, McCallum SE, Marks MJ, Musachio J, McIntosh JM, Collins AC, Grady SR. Differential declines in striatal nicotinic receptor subtype function after nigrostriatal damage in mice. Mol Pharmacol. 2003 May; 63(5):1169-79.
    View in: PubMed
    Score: 0.014
  13. Grady SR, Murphy KL, Cao J, Marks MJ, McIntosh JM, Collins AC. Characterization of nicotinic agonist-induced [(3)H]dopamine release from synaptosomes prepared from four mouse brain regions. J Pharmacol Exp Ther. 2002 May; 301(2):651-60.
    View in: PubMed
    Score: 0.013
  14. Parker RL, O'Neill HC, Henley BM, Wageman CR, Drenan RM, Marks MJ, Miwa JM, Grady SR, Lester HA. Deletion of lynx1 reduces the function of a6* nicotinic receptors. PLoS One. 2017; 12(12):e0188715.
    View in: PubMed
    Score: 0.010
  15. McClure-Begley TD, Grady SR, Marks MJ, Collins AC, Stitzel JA. Presynaptic GABAB autoreceptor regulation of nicotinic acetylcholine receptor mediated [(3)H]-GABA release from mouse synaptosomes. Biochem Pharmacol. 2014 Sep 01; 91(1):87-96.
    View in: PubMed
    Score: 0.008
  16. Marks MJ, Grady SR, Salminen O, Paley MA, Wageman CR, McIntosh JM, Whiteaker P. a6ß2*-subtype nicotinic acetylcholine receptors are more sensitive than a4ß2*-subtype receptors to regulation by chronic nicotine administration. J Neurochem. 2014 Jul; 130(2):185-98.
    View in: PubMed
    Score: 0.008
  17. Wang Y, Lee JW, Oh G, Grady SR, McIntosh JM, Brunzell DH, Cannon JR, Drenan RM. Enhanced synthesis and release of dopamine in transgenic mice with gain-of-function a6* nAChRs. J Neurochem. 2014 Apr; 129(2):315-27.
    View in: PubMed
    Score: 0.007
  18. McClure-Begley TD, Stone KL, Marks MJ, Grady SR, Colangelo CM, Lindstrom JM, Picciotto MR. Exploring the nicotinic acetylcholine receptor-associated proteome with iTRAQ and transgenic mice. Genomics Proteomics Bioinformatics. 2013 Aug; 11(4):207-18.
    View in: PubMed
    Score: 0.007
  19. Soll LG, Grady SR, Salminen O, Marks MJ, Tapper AR. A role for a4(non-a6)* nicotinic acetylcholine receptors in motor behavior. Neuropharmacology. 2013 Oct; 73:19-30.
    View in: PubMed
    Score: 0.007
  20. Sala M, Braida D, Pucci L, Manfredi I, Marks MJ, Wageman CR, Grady SR, Loi B, Fucile S, Fasoli F, Zoli M, Tasso B, Sparatore F, Clementi F, Gotti C. CC4, a dimer of cytisine, is a selective partial agonist at a4ß2/a6ß2 nAChR with improved selectivity for tobacco smoking cessation. Br J Pharmacol. 2013 Feb; 168(4):835-49.
    View in: PubMed
    Score: 0.007
  21. O'Neill HC, Laverty DC, Patzlaff NE, Cohen BN, Fonck C, McKinney S, McIntosh JM, Lindstrom JM, Lester HA, Grady SR, Marks MJ. Mice expressing the ADNFLE valine 287 leucine mutation of the ?2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function. Pharmacol Biochem Behav. 2013 Jan; 103(3):603-21.
    View in: PubMed
    Score: 0.007
  22. Mackey ED, Engle SE, Kim MR, O'Neill HC, Wageman CR, Patzlaff NE, Wang Y, Grady SR, McIntosh JM, Marks MJ, Lester HA, Drenan RM. a6* nicotinic acetylcholine receptor expression and function in a visual salience circuit. J Neurosci. 2012 Jul 25; 32(30):10226-37.
    View in: PubMed
    Score: 0.007
  23. McClure-Begley TD, Wageman CR, Grady SR, Marks MJ, McIntosh JM, Collins AC, Whiteaker P. A novel a-conotoxin MII-sensitive nicotinic acetylcholine receptor modulates [(3) H]-GABA release in the superficial layers of the mouse superior colliculus. J Neurochem. 2012 Jul; 122(1):48-57.
    View in: PubMed
    Score: 0.007
  24. Zambrano CA, Salamander RM, Collins AC, Grady SR, Marks MJ. Regulation of the distribution and function of [(125)I]epibatidine binding sites by chronic nicotine in mouse embryonic neuronal cultures. J Pharmacol Exp Ther. 2012 Aug; 342(2):245-54.
    View in: PubMed
    Score: 0.007
  25. McGranahan TM, Patzlaff NE, Grady SR, Heinemann SF, Booker TK. a4ß2 nicotinic acetylcholine receptors on dopaminergic neurons mediate nicotine reward and anxiety relief. J Neurosci. 2011 Jul 27; 31(30):10891-902.
    View in: PubMed
    Score: 0.006
  26. Huang LZ, Grady SR, Quik M. Nicotine reduces L-DOPA-induced dyskinesias by acting at beta2* nicotinic receptors. J Pharmacol Exp Ther. 2011 Sep; 338(3):932-41.
    View in: PubMed
    Score: 0.006
  27. Zhao-Shea R, Liu L, Soll LG, Improgo MR, Meyers EE, McIntosh JM, Grady SR, Marks MJ, Gardner PD, Tapper AR. Nicotine-mediated activation of dopaminergic neurons in distinct regions of the ventral tegmental area. Neuropsychopharmacology. 2011 Apr; 36(5):1021-32.
    View in: PubMed
    Score: 0.006
  28. Drenan RM, Grady SR, Steele AD, McKinney S, Patzlaff NE, McIntosh JM, Marks MJ, Miwa JM, Lester HA. Cholinergic modulation of locomotion and striatal dopamine release is mediated by alpha6alpha4* nicotinic acetylcholine receptors. J Neurosci. 2010 Jul 21; 30(29):9877-89.
    View in: PubMed
    Score: 0.006
  29. Zhao-Shea R, Cohen BN, Just H, McClure-Begley T, Whiteaker P, Grady SR, Salminen O, Gardner PD, Lester HA, Tapper AR. Dopamine D2-receptor activation elicits akinesia, rigidity, catalepsy, and tremor in mice expressing hypersensitive {alpha}4 nicotinic receptors via a cholinergic-dependent mechanism. FASEB J. 2010 Jan; 24(1):49-57.
    View in: PubMed
    Score: 0.006
  30. Marks MJ, Laverty DS, Whiteaker P, Salminen O, Grady SR, McIntosh JM, Collins AC. John Daly's compound, epibatidine, facilitates identification of nicotinic receptor subtypes. J Mol Neurosci. 2010 Jan; 40(1-2):96-104.
    View in: PubMed
    Score: 0.006
  31. Marks MJ, Wageman CR, Grady SR, Gopalakrishnan M, Briggs CA. Selectivity of ABT-089 for alpha4beta2* and alpha6beta2* nicotinic acetylcholine receptors in brain. Biochem Pharmacol. 2009 Oct 01; 78(7):795-802.
    View in: PubMed
    Score: 0.005
  32. Breining SR, Bencherif M, Grady SR, Whiteaker P, Marks MJ, Wageman CR, Lester HA, Yohannes D. Evaluation of structurally diverse neuronal nicotinic receptor ligands for selectivity at the alpha6( *) subtype. Bioorg Med Chem Lett. 2009 Aug 01; 19(15):4359-63.
    View in: PubMed
    Score: 0.005
  33. Drenan RM, Grady SR, Whiteaker P, McClure-Begley T, McKinney S, Miwa JM, Bupp S, Heintz N, McIntosh JM, Bencherif M, Marks MJ, Lester HA. In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors. Neuron. 2008 Oct 09; 60(1):123-36.
    View in: PubMed
    Score: 0.005
  34. Perez XA, Bordia T, McIntosh JM, Grady SR, Quik M. Long-term nicotine treatment differentially regulates striatal alpha6alpha4beta2* and alpha6(nonalpha4)beta2* nAChR expression and function. Mol Pharmacol. 2008 Sep; 74(3):844-53.
    View in: PubMed
    Score: 0.005
  35. Teper Y, Whyte D, Cahir E, Lester HA, Grady SR, Marks MJ, Cohen BN, Fonck C, McClure-Begley T, McIntosh JM, Labarca C, Lawrence A, Chen F, Gantois I, Davies PJ, Petrou S, Murphy M, Waddington J, Horne MK, Berkovic SF, Drago J. Nicotine-induced dystonic arousal complex in a mouse line harboring a human autosomal-dominant nocturnal frontal lobe epilepsy mutation. J Neurosci. 2007 Sep 19; 27(38):10128-42.
    View in: PubMed
    Score: 0.005
  36. Nashmi R, Xiao C, Deshpande P, McKinney S, Grady SR, Whiteaker P, Huang Q, McClure-Begley T, Lindstrom JM, Labarca C, Collins AC, Marks MJ, Lester HA. Chronic nicotine cell specifically upregulates functional alpha 4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path. J Neurosci. 2007 Aug 01; 27(31):8202-18.
    View in: PubMed
    Score: 0.005
  37. Bordia T, Grady SR, McIntosh JM, Quik M. Nigrostriatal damage preferentially decreases a subpopulation of alpha6beta2* nAChRs in mouse, monkey, and Parkinson's disease striatum. Mol Pharmacol. 2007 Jul; 72(1):52-61.
    View in: PubMed
    Score: 0.005
  38. Salminen O, Whiteaker P, Grady SR, Collins AC, McIntosh JM, Marks MJ. The subunit composition and pharmacology of alpha-Conotoxin MII-binding nicotinic acetylcholine receptors studied by a novel membrane-binding assay. Neuropharmacology. 2005 Apr; 48(5):696-705.
    View in: PubMed
    Score: 0.004
  39. Lai A, Parameswaran N, Khwaja M, Whiteaker P, Lindstrom JM, Fan H, McIntosh JM, Grady SR, Quik M. Long-term nicotine treatment decreases striatal alpha 6* nicotinic acetylcholine receptor sites and function in mice. Mol Pharmacol. 2005 May; 67(5):1639-47.
    View in: PubMed
    Score: 0.004
  40. Marks MJ, Rowell PP, Cao JZ, Grady SR, McCallum SE, Collins AC. Subsets of acetylcholine-stimulated 86Rb+ efflux and [125I]-epibatidine binding sites in C57BL/6 mouse brain are differentially affected by chronic nicotine treatment. Neuropharmacology. 2004 Jun; 46(8):1141-57.
    View in: PubMed
    Score: 0.004
  41. Cui C, Booker TK, Allen RS, Grady SR, Whiteaker P, Marks MJ, Salminen O, Tritto T, Butt CM, Allen WR, Stitzel JA, McIntosh JM, Boulter J, Collins AC, Heinemann SF. The beta3 nicotinic receptor subunit: a component of alpha-conotoxin MII-binding nicotinic acetylcholine receptors that modulate dopamine release and related behaviors. J Neurosci. 2003 Dec 03; 23(35):11045-53.
    View in: PubMed
    Score: 0.004
  42. King SL, Marks MJ, Grady SR, Caldarone BJ, Koren AO, Mukhin AG, Collins AC, Picciotto MR. Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior. J Neurosci. 2003 May 01; 23(9):3837-43.
    View in: PubMed
    Score: 0.004
  43. Marks MJ, Whiteaker P, Grady SR, Picciotto MR, McIntosh JM, Collins AC. Characterization of [(125) I]epibatidine binding and nicotinic agonist-mediated (86) Rb(+) efflux in interpeduncular nucleus and inferior colliculus of beta2 null mutant mice. J Neurochem. 2002 Jun; 81(5):1102-15.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Copyright © 2026 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)