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Connection

Charles Dinarello to Interleukin-2

This is a "connection" page, showing publications Charles Dinarello has written about Interleukin-2.

 
Connection Strength
 
 
 
0.955
 
  1. Endres S, Meydani SN, Ghorbani R, Schindler R, Dinarello CA. Dietary supplementation with n-3 fatty acids suppresses interleukin-2 production and mononuclear cell proliferation. J Leukoc Biol. 1993 Dec; 54(6):599-603.
    View in: PubMed
    Score: 0.094
  2. Ye K, Koch KC, Clark BD, Dinarello CA. Interleukin-1 down-regulates gene and surface expression of interleukin-1 receptor type I by destabilizing its mRNA whereas interleukin-2 increases its expression. Immunology. 1992 Mar; 75(3):427-34.
    View in: PubMed
    Score: 0.083
  3. Dinarello CA. The proinflammatory cytokines interleukin-1 and tumor necrosis factor and treatment of the septic shock syndrome. J Infect Dis. 1991 Jun; 163(6):1177-84.
    View in: PubMed
    Score: 0.079
  4. Endres S, Cannon JG, Ghorbani R, Dempsey RA, Sisson SD, Lonnemann G, Van der Meer JW, Wolff SM, Dinarello CA. In vitro production of IL 1 beta, IL 1 alpha, TNF and IL2 in healthy subjects: distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation. Eur J Immunol. 1989 Dec; 19(12):2327-33.
    View in: PubMed
    Score: 0.071
  5. Mier JW, Vachino G, van der Meer JW, Numerof RP, Adams S, Cannon JG, Bernheim HA, Atkins MB, Parkinson DR, Dinarello CA. Induction of circulating tumor necrosis factor (TNF alpha) as the mechanism for the febrile response to interleukin-2 (IL-2) in cancer patients. J Clin Immunol. 1988 Nov; 8(6):426-36.
    View in: PubMed
    Score: 0.066
  6. Dinarello CA, Mier JW. Interleukins. Annu Rev Med. 1986; 37:173-8.
    View in: PubMed
    Score: 0.054
  7. Mier JW, Souza LM, Allegretta M, Boone T, Bernheim HA, Dinarello CA. Dissimilarities between purified human interleukin-1 and recombinant human interleukin-2 in the induction of fever, brain prostaglandin, and acute-phase protein synthesis. J Biol Response Mod. 1985 Feb; 4(1):35-45.
    View in: PubMed
    Score: 0.051
  8. Dinarello CA. Cytokines as endogenous pyrogens. J Infect Dis. 1999 Mar; 179 Suppl 2:S294-304.
    View in: PubMed
    Score: 0.034
  9. Vannier E, Kaser A, Atkins MB, Fantuzzi G, Dinarello CA, Mier JW, Tilg H. Elevated circulating levels of soluble interleukin-1 receptor type II during interleukin-2 immunotherapy. Eur Cytokine Netw. 1999 Mar; 10(1):37-42.
    View in: PubMed
    Score: 0.034
  10. Du Bois JS, Trehu EG, Mier JW, Shapiro L, Epstein M, Klempner M, Dinarello C, Kappler K, Ronayne L, Rand W, Atkins MB. Randomized placebo-controlled clinical trial of high-dose interleukin-2 in combination with a soluble p75 tumor necrosis factor receptor immunoglobulin G chimera in patients with advanced melanoma and renal cell carcinoma. J Clin Oncol. 1997 Mar; 15(3):1052-62.
    View in: PubMed
    Score: 0.030
  11. Trehu EG, Mier JW, Dubois JS, Sorce D, Klempner MS, Epstein M, Dinarello CA, Shapiro L, Kappler K, Ronayne L, Atkins MB. Phase I trial of interleukin 2 in combination with the soluble tumor necrosis factor receptor p75 IgG chimera. Clin Cancer Res. 1996 Aug; 2(8):1341-51.
    View in: PubMed
    Score: 0.028
  12. Tilg H, Shapiro L, Vannier E, Poutsiaka DD, Trehu E, Atkins MB, Dinarello CA, Mier JW. Induction of circulating antagonists to IL-1 and TNF by IL-2 administration and their effects on IL-2 induced cytokine production in vitro. J Immunol. 1994 Mar 15; 152(6):3189-98.
    View in: PubMed
    Score: 0.024
  13. Tilg H, Shapiro L, Atkins MB, Dinarello CA, Mier JW. Induction of circulating and erythrocyte-bound IL-8 by IL-2 immunotherapy and suppression of its in vitro production by IL-1 receptor antagonist and soluble tumor necrosis factor receptor (p75) chimera. J Immunol. 1993 Sep 15; 151(6):3299-307.
    View in: PubMed
    Score: 0.023
  14. Numerof RP, Sipe JD, Trehu EG, Dinarello CA, Mier JW. Suppression of IL-2-induced SAA gene expression in mice by the administration of an IL-1 receptor antagonist. Cytokine. 1992 Nov; 4(6):555-60.
    View in: PubMed
    Score: 0.022
  15. Numerof RP, Kotik AN, Dinarello CA, Mier JW. Pro-interleukin-1 beta production by a subpopulation of human T cells, but not NK cells, in response to interleukin-2. Cell Immunol. 1990 Oct 01; 130(1):118-28.
    View in: PubMed
    Score: 0.019
  16. Park MM, Hornback NB, Endres S, Dinarello CA. The effect of whole body hyperthermia on the immune cell activity of cancer patients. Lymphokine Res. 1990; 9(2):213-23.
    View in: PubMed
    Score: 0.018
  17. Straus SE, Dale JK, Peter JB, Dinarello CA. Circulating lymphokine levels in the chronic fatigue syndrome. J Infect Dis. 1989 Dec; 160(6):1085-6.
    View in: PubMed
    Score: 0.018
  18. Savage N, Puren AJ, Orencole SF, Ikejima T, Clark BD, Dinarello CA. Studies on IL-1 receptors on D10S T-helper cells: demonstration of two molecularly and antigenically distinct IL-1 binding proteins. Cytokine. 1989 Nov; 1(1):23-35.
    View in: PubMed
    Score: 0.018
  19. Dinarello CA, Cannon JG, Wolff SM. New concepts on the pathogenesis of fever. Rev Infect Dis. 1988 Jan-Feb; 10(1):168-89.
    View in: PubMed
    Score: 0.016
  20. Conti P, Reale M, Angeletti PU, Dinarello CA. Restoration of anti-interleukin-1 depressed natural killer activity by human recombinant interferon alpha or gamma, human recombinant interleukin-2 and indomethacin. Int J Immunopharmacol. 1988; 10(8):907-11.
    View in: PubMed
    Score: 0.016
  21. Dinarello CA, Mier JW. Lymphokines. N Engl J Med. 1987 Oct 08; 317(15):940-5.
    View in: PubMed
    Score: 0.015
  22. Mier JW, Dinarello CA, Atkins MB, Punsal PI, Perlmutter DH. Regulation of hepatic acute phase protein synthesis by products of interleukin 2 (IL 2)-stimulated human peripheral blood mononuclear cells. J Immunol. 1987 Aug 15; 139(4):1268-72.
    View in: PubMed
    Score: 0.015
  23. Dinarello CA, Dempsey RA, Allegretta M, LoPreste G, Dainiak N, Parkinson DR, Mier JW. Inhibitory effects of elevated temperature on human cytokine production and natural killer activity. Cancer Res. 1986 Dec; 46(12 Pt 1):6236-41.
    View in: PubMed
    Score: 0.015
  24. Cannon JG, Tatro JB, Reichlin S, Dinarello CA. Alpha melanocyte stimulating hormone inhibits immunostimulatory and inflammatory actions of interleukin 1. J Immunol. 1986 Oct 01; 137(7):2232-6.
    View in: PubMed
    Score: 0.014
  25. Hofman FM, von Hanwehr RI, Dinarello CA, Mizel SB, Hinton D, Merrill JE. Immunoregulatory molecules and IL 2 receptors identified in multiple sclerosis brain. J Immunol. 1986 May 01; 136(9):3239-45.
    View in: PubMed
    Score: 0.014
  26. Dempsey RA, Dinarello CA, Mier JW, Rosenwasser LJ, Allegretta M, Brown TE, Parkinson DR. The differential effects of human leukocyte pyrogen/lymphocyte-activating factor, T cell growth factor, and interferon on human natural killer activity. J Immunol. 1982 Dec; 129(6):2504-10.
    View in: PubMed
    Score: 0.011
  27. Dinarello CA, Dempsey RA, Mier JW, Rosenwasser LJ, Parkinson DR. Fever, interleukin-1 and host defense against malignancy. Lymphokine Res. 1982; 1(3):59-67.
    View in: PubMed
    Score: 0.010
  28. Tilg H, Atkins MB, Dinarello CA, Mier JW. Induction of circulating interleukin 10 by interleukin 1 and interleukin 2, but not interleukin 6 immunotherapy. Cytokine. 1995 Oct; 7(7):734-9.
    View in: PubMed
    Score: 0.007
  29. Tilg H, Vannier E, Vachino G, Dinarello CA, Mier JW. Antiinflammatory properties of hepatic acute phase proteins: preferential induction of interleukin 1 (IL-1) receptor antagonist over IL-1 beta synthesis by human peripheral blood mononuclear cells. J Exp Med. 1993 Nov 01; 178(5):1629-36.
    View in: PubMed
    Score: 0.006
  30. Avraham H, Vannier E, Cowley S, Jiang SX, Chi S, Dinarello CA, Zsebo KM, Groopman JE. Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells. Blood. 1992 Jan 15; 79(2):365-71.
    View in: PubMed
    Score: 0.005
  31. Tsoukas CD, Watry D, Escobar SS, Provvedini DM, Dinarello CA, Hustmyer FG, Manolagas SC. Inhibition of interleukin-1 production by 1,25-dihydroxyvitamin D3. J Clin Endocrinol Metab. 1989 Jul; 69(1):127-33.
    View in: PubMed
    Score: 0.004
  32. Gottlieb RA, Lennarz WJ, Knowles RD, Cianciolo GJ, Dinarello CA, Lachman LB, Kleinerman ES. Synthetic peptide corresponding to a conserved domain of the retroviral protein p15E blocks IL-1-mediated signal transduction. J Immunol. 1989 Jun 15; 142(12):4321-8.
    View in: PubMed
    Score: 0.004
  33. Prakash S, Dinarello CA, Danko K, Stadecker MJ, Wyler DJ. Schistosomal egg granuloma-derived fibroblast-stimulating factor is apparently distinct from interleukin-1. Infect Immun. 1989 Mar; 57(3):679-84.
    View in: PubMed
    Score: 0.004
  34. Rustgi VK, Jones DB, Dinarello CA, Hoofnagle JH. Lymphokines and bile secretion in the rat. Liver. 1987 Jun; 7(3):149-54.
    View in: PubMed
    Score: 0.004
  35. Fauci AS, Rosenberg SA, Sherwin SA, Dinarello CA, Longo DL, Lane HC. NIH conference. Immunomodulators in clinical medicine. Ann Intern Med. 1987 Mar; 106(3):421-33.
    View in: PubMed
    Score: 0.004
  36. Yodoi J, Okada M, Tagaya Y, Taniguchi Y, Teshigawara K, Kasahara T, Dinarello CA, Matsushima K, Honko T, Uchiyama T, et al. IL-2 receptor gene activation by ATL-derived factor (ADF). Adv Exp Med Biol. 1987; 213:139-48.
    View in: PubMed
    Score: 0.004
  37. Lotz M, Tsoukas CD, Robinson CA, Dinarello CA, Carson DA, Vaughan JH. Basis for defective responses of rheumatoid arthritis synovial fluid lymphocytes to anti-CD3 (T3) antibodies. J Clin Invest. 1986 Sep; 78(3):713-21.
    View in: PubMed
    Score: 0.004
  38. Lotz M, Tsoukas CD, Fong S, Dinarello CA, Carson DA, Vaughan JH. Release of lymphokines after Epstein Barr virus infection in vitro. I. Sources of and kinetics of production of interferons and interleukins in normal humans. J Immunol. 1986 May 15; 136(10):3636-42.
    View in: PubMed
    Score: 0.003
  39. Lotz M, Tsoukas CD, Fong S, Dinarello CA, Carson DA, Vaughan JH. Release of lymphokines after infection with Epstein Barr virus in vitro. II. A monocyte-dependent inhibitor of interleukin 1 downregulates the production of interleukin 2 and interferon-gamma in rheumatoid arthritis. J Immunol. 1986 May 15; 136(10):3643-8.
    View in: PubMed
    Score: 0.003
  40. Peters M, Butler JL, Margolick JB, Gerrard TL, Dinarello CA, Fauci AS. Synergy of helper factors in the differentiation of in vivo-preactivated antigen-specific human B cells. Cell Immunol. 1985 Mar; 91(1):33-42.
    View in: PubMed
    Score: 0.003
  41. Kaye J, Gillis S, Mizel SB, Shevach EM, Malek TR, Dinarello CA, Lachman LB, Janeway CA. Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2. J Immunol. 1984 Sep; 133(3):1339-45.
    View in: PubMed
    Score: 0.003
  42. Chu ET, Rosenwasser LJ, Dinarello CA, Rosen FS, Geha RS. Immunodeficiency with defective T-cell response to interleukin 1. Proc Natl Acad Sci U S A. 1984 Aug; 81(15):4945-9.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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