 Connection
Charles Dinarello to Rats
This is a "connection" page, showing publications Charles Dinarello has written about Rats.
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0.557 |
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Olson JL, Courtney RJ, Rouhani B, Mandava N, Dinarello CA. Intravitreal anakinra inhibits choroidal neovascular membrane growth in a rat model. Ocul Immunol Inflamm. 2009 May-Jun; 17(3):195-200.
Score: 0.040
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Dinarello CA, Muegge K, Durum SK. Measurement of soluble and membrane-bound interleukin 1 using a fibroblast bioassay. Curr Protoc Immunol. 2001 May; Chapter 6:Unit 6.2.
Score: 0.023
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Dinarello CA, Novick D, Puren AJ, Fantuzzi G, Shapiro L, Mühl H, Yoon DY, Reznikov LL, Kim SH, Rubinstein M. Overview of interleukin-18: more than an interferon-gamma inducing factor. J Leukoc Biol. 1998 Jun; 63(6):658-64.
Score: 0.019
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Jeong MY, Lin YH, Wennersten SA, Demos-Davies KM, Cavasin MA, Mahaffey JH, Monzani V, Saripalli C, Mascagni P, Reece TB, Ambardekar AV, Granzier HL, Dinarello CA, McKinsey TA. Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism. Sci Transl Med. 2018 02 07; 10(427).
Score: 0.018
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Needell JC, Dinarello CA, Ir D, Robertson CE, Ryan SM, Kroehl ME, Frank DN, Zipris D. Implication of the intestinal microbiome as a potential surrogate marker of immune responsiveness to experimental therapies in autoimmune diabetes. PLoS One. 2017; 12(3):e0173968.
Score: 0.017
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Dinarello CA. Biologic basis for interleukin-1 in disease. Blood. 1996 Mar 15; 87(6):2095-147.
Score: 0.016
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Christensen DP, Gysemans C, Lundh M, Dahllöf MS, Noesgaard D, Schmidt SF, Mandrup S, Birkbak N, Workman CT, Piemonti L, Blaabjerg L, Monzani V, Fossati G, Mascagni P, Paraskevas S, Aikin RA, Billestrup N, Grunnet LG, Dinarello CA, Mathieu C, Mandrup-Poulsen T. Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and ß-cell protection. Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3):1055-9.
Score: 0.014
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Hara N, Alkanani AK, Dinarello CA, Zipris D. Modulation of virus-induced innate immunity and type 1 diabetes by IL-1 blockade. Innate Immun. 2014 Aug; 20(6):574-84.
Score: 0.013
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Mancilla-Ramírez J, Ramírez-Herrera M, Portillo-Gómez L, Gaitán-Meza J, Dinarello CA. [Antagonists in neonatal sepsis]. Bol Med Hosp Infant Mex. 1993 Sep; 50(9):691-3.
Score: 0.013
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Hara N, Alkanani AK, Dinarello CA, Zipris D. Histone deacetylase inhibitor suppresses virus-induced proinflammatory responses and type 1 diabetes. J Mol Med (Berl). 2014 Jan; 92(1):93-102.
Score: 0.013
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Kratzer A, Salys J, Nold-Petry C, Cool C, Zamora M, Bowler R, Koczulla AR, Janciauskiene S, Edwards MG, Dinarello CA, Taraseviciene-Stewart L. Role of IL-18 in second-hand smoke-induced emphysema. Am J Respir Cell Mol Biol. 2013 Jun; 48(6):725-32.
Score: 0.013
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Mancilla J, García P, Dinarello CA. The interleukin-1 receptor antagonist can either reduce or enhance the lethality of Klebsiella pneumoniae sepsis in newborn rats. Infect Immun. 1993 Mar; 61(3):926-32.
Score: 0.013
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Dahllöf MS, Christensen DP, Lundh M, Dinarello CA, Mascagni P, Grunnet LG, Mandrup-Poulsen T. The lysine deacetylase inhibitor Givinostat inhibits ß-cell IL-1ß induced IL-1ß transcription and processing. Islets. 2012 Nov-Dec; 4(6):417-22.
Score: 0.013
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Lundh M, Christensen DP, Damgaard Nielsen M, Richardson SJ, Dahllöf MS, Skovgaard T, Berthelsen J, Dinarello CA, Stevenazzi A, Mascagni P, Grunnet LG, Morgan NG, Mandrup-Poulsen T. Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children. Diabetologia. 2012 Sep; 55(9):2421-31.
Score: 0.012
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Lewis EC, Blaabjerg L, Størling J, Ronn SG, Mascagni P, Dinarello CA, Mandrup-Poulsen T. The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet ß cells in vivo and in vitro. Mol Med. 2011 May-Jun; 17(5-6):369-77.
Score: 0.011
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Lundh M, Christensen DP, Rasmussen DN, Mascagni P, Dinarello CA, Billestrup N, Grunnet LG, Mandrup-Poulsen T. Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines. Diabetologia. 2010 Dec; 53(12):2569-78.
Score: 0.011
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Orencole SF, Dinarello CA. Characterization of a subclone (D10S) of the D10.G4.1 helper T-cell line which proliferates to attomolar concentrations of interleukin-1 in the absence of mitogens. Cytokine. 1989 Nov; 1(1):14-22.
Score: 0.010
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Wang M, Tan J, Wang Y, Meldrum KK, Dinarello CA, Meldrum DR. IL-18 binding protein-expressing mesenchymal stem cells improve myocardial protection after ischemia or infarction. Proc Natl Acad Sci U S A. 2009 Oct 13; 106(41):17499-504.
Score: 0.010
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Hellerstein MK, Meydani SN, Meydani M, Wu K, Dinarello CA. Interleukin-1-induced anorexia in the rat. Influence of prostaglandins. J Clin Invest. 1989 Jul; 84(1):228-35.
Score: 0.010
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Dinarello CA, Savage N. Interleukin-1 and its receptor. Crit Rev Immunol. 1989; 9(1):1-20.
Score: 0.010
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Manzer R, Dinarello CA, McConville G, Mason RJ. Ozone exposure of macrophages induces an alveolar epithelial chemokine response through IL-1alpha. Am J Respir Cell Mol Biol. 2008 Mar; 38(3):318-23.
Score: 0.009
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Lorenzo JA, Sousa SL, Alander C, Raisz LG, Dinarello CA. Comparison of the bone-resorbing activity in the supernatants from phytohemagglutinin-stimulated human peripheral blood mononuclear cells with that of cytokines through the use of an antiserum to interleukin 1. Endocrinology. 1987 Sep; 121(3):1164-70.
Score: 0.009
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Lavi G, Voronov E, Dinarello CA, Apte RN, Cohen S. Sustained delivery of IL-1 Ra from biodegradable microspheres reduces the number of murine B16 melanoma lung metastases. J Control Release. 2007 Nov 06; 123(2):123-30.
Score: 0.009
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Mandrup-Poulsen T, Egeberg J, Nerup J, Bendtzen K, Nielsen JH, Dinarello CA. Ultrastructural studies of time-course and cellular specificity of interleukin-1 mediated islet cytotoxicity. Acta Pathol Microbiol Immunol Scand C. 1987 Apr; 95(2):55-63.
Score: 0.009
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Gauldie J, Sauder DN, McAdam KP, Dinarello CA. Purified interleukin-1 (IL-1) from human monocytes stimulates acute-phase protein synthesis by rodent hepatocytes in vitro. Immunology. 1987 Feb; 60(2):203-7.
Score: 0.009
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Larsen L, Tonnesen M, Ronn SG, Størling J, Jørgensen S, Mascagni P, Dinarello CA, Billestrup N, Mandrup-Poulsen T. Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells. Diabetologia. 2007 Apr; 50(4):779-89.
Score: 0.009
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Meldrum KK, Misseri R, Metcalfe P, Dinarello CA, Hile KL, Meldrum DR. TNF-alpha neutralization ameliorates obstruction-induced renal fibrosis and dysfunction. Am J Physiol Regul Integr Comp Physiol. 2007 Apr; 292(4):R1456-64.
Score: 0.008
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Besedovsky H, del Rey A, Sorkin E, Dinarello CA. Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones. Science. 1986 Aug 08; 233(4764):652-4.
Score: 0.008
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Conti P, Cifone MG, Alesse E, Reale M, Fieschi C, Dinarello CA. In vitro enhanced thromboxane B2 release by polymorphonuclear leukocytes and macrophages after treatment with human recombinant interleukin 1. Prostaglandins. 1986 Jul; 32(1):111-5.
Score: 0.008
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Dinarello CA. Studies on the biological properties of purified and recombinant human interleukin-1. Methods Find Exp Clin Pharmacol. 1986 Feb; 8(2):57-61.
Score: 0.008
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Portnoy J, Pan T, Dinarello CA, Shannon JM, Westcott JY, Zhang L, Mason RJ. Alveolar type II cells inhibit fibroblast proliferation: role of IL-1alpha. Am J Physiol Lung Cell Mol Physiol. 2006 Feb; 290(2):L307-16.
Score: 0.008
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Misseri R, Meldrum DR, Dinarello CA, Dagher P, Hile KL, Rink RC, Meldrum KK. TNF-alpha mediates obstruction-induced renal tubular cell apoptosis and proapoptotic signaling. Am J Physiol Renal Physiol. 2005 Feb; 288(2):F406-11.
Score: 0.007
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Dinarello CA, Clowes GH, Gordon AH, Saravis CA, Wolff SM. Cleavage of human interleukin 1: isolation of a peptide fragment from plasma of febrile humans and activated monocytes. J Immunol. 1984 Sep; 133(3):1332-8.
Score: 0.007
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Goldberg AL, Baracos V, Rodemann P, Waxman L, Dinarello C. Control of protein degradation in muscle by prostaglandins, Ca2+, and leukocytic pyrogen (interleukin 1). Fed Proc. 1984 Apr; 43(5):1301-6.
Score: 0.007
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Wang M, Sankula R, Tsai BM, Meldrum KK, Turrentine M, March KL, Brown JW, Dinarello CA, Meldrum DR. P38 MAPK mediates myocardial proinflammatory cytokine production and endotoxin-induced contractile suppression. Shock. 2004 Feb; 21(2):170-4.
Score: 0.007
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Im SH, Kim SH, Azam T, Venkatesh N, Dinarello CA, Fuchs S, Souroujon MC. Rat interleukin-18 binding protein: cloning, expression, and characterization. J Interferon Cytokine Res. 2002 Mar; 22(3):321-8.
Score: 0.006
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Calkins CM, Bensard DD, Shames BD, Pulido EJ, Abraham E, Fernandez N, Meng X, Dinarello CA, McIntyre RC. IL-1 regulates in vivo C-X-C chemokine induction and neutrophil sequestration following endotoxemia. J Endotoxin Res. 2002; 8(1):59-67.
Score: 0.006
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Hong TP, Andersen NA, Nielsen K, Karlsen AE, Fantuzzi G, Eizirik DL, Dinarello CA, Mandrup-Poulsen T. Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma. Eur Cytokine Netw. 2000 Jun; 11(2):193-205.
Score: 0.005
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Sheridan BC, Dinarello CA, Meldrum DR, Fullerton DA, Selzman CH, McIntyre RC. Interleukin-11 attenuates pulmonary inflammation and vasomotor dysfunction in endotoxin-induced lung injury. Am J Physiol. 1999 11; 277(5):L861-7.
Score: 0.005
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Meldrum DR, Dinarello CA, Shames BD, Cleveland JC, Cain BS, Banerjee A, Meng X, Harken AH. Ischemic preconditioning decreases postischemic myocardial tumor necrosis factor-alpha production. Potential ultimate effector mechanism of preconditioning. Circulation. 1998 Nov 10; 98(19 Suppl):II214-8; discussion II218-9.
Score: 0.005
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Meldrum DR, Dinarello CA, Cleveland JC, Cain BS, Shames BD, Meng X, Harken AH. Hydrogen peroxide induces tumor necrosis factor alpha-mediated cardiac injury by a P38 mitogen-activated protein kinase-dependent mechanism. Surgery. 1998 Aug; 124(2):291-6; discussion 297.
Score: 0.005
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Larsen CM, Wadt KA, Juhl LF, Andersen HU, Karlsen AE, Su MS, Seedorf K, Shapiro L, Dinarello CA, Mandrup-Poulsen T. Interleukin-1beta-induced rat pancreatic islet nitric oxide synthesis requires both the p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases. J Biol Chem. 1998 Jun 12; 273(24):15294-300.
Score: 0.005
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Badovinac V, Mostarica-Stojkovic M, Dinarello CA, Stosic-Grujicic S. Interleukin-1 receptor antagonist suppresses experimental autoimmune encephalomyelitis (EAE) in rats by influencing the activation and proliferation of encephalitogenic cells. J Neuroimmunol. 1998 May 01; 85(1):87-95.
Score: 0.005
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Cain BS, Meldrum DR, Dinarello CA, Meng X, Banerjee A, Harken AH. Adenosine reduces cardiac TNF-alpha production and human myocardial injury following ischemia-reperfusion. J Surg Res. 1998 May; 76(2):117-23.
Score: 0.005
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Roubenoff R, Freeman LM, Smith DE, Abad LW, Dinarello CA, Kehayias JJ. Adjuvant arthritis as a model of inflammatory cachexia. Arthritis Rheum. 1997 Mar; 40(3):534-9.
Score: 0.004
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Torcia M, Lucibello M, Vannier E, Fabiani S, Miliani A, Guidi G, Spada O, Dower SK, Sims JE, Shaw AR, Dinarello CA, Garaci E, Cozzolino F. Modulation of osteoclast-activating factor activity of multiple myeloma bone marrow cells by different interleukin-1 inhibitors. Exp Hematol. 1996 Jul; 24(8):868-74.
Score: 0.004
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Mancilla-Ramírez J, Dinarello CA, Santos-Preciado JI. [Phosphatidylcholine induces an increase in the production of interleukin-6 and improves survival of rats with neonatal sepsis caused by Klebsiella pneumoniae]. Gac Med Mex. 1995 Jan-Feb; 131(1):14-22.
Score: 0.004
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Mester M, Carter EA, Tompkins RG, Gelfand JA, Dinarello CA, Burke JF, Clark BD. Thermal injury induces very early production of interleukin-1 alpha in the rat by mechanisms other than endotoxemia. Surgery. 1994 May; 115(5):588-96.
Score: 0.004
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Zumsteg U, Reimers JI, Pociot F, Mørch L, Helqvist S, Brendel M, Alejandro R, Mandrup-Poulsen T, Dinarello CA, Nerup J. Differential interleukin-1 receptor antagonism on pancreatic beta and alpha cells. Studies in rodent and human islets and in normal rats. Diabetologia. 1993 Aug; 36(8):759-66.
Score: 0.003
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Romero LI, Schettini G, Lechan RM, Dinarello CA, Reichlin S. Bacterial lipopolysaccharide induction of IL-6 in rat telencephalic cells is mediated in part by IL-1. Neuroendocrinology. 1993 May; 57(5):892-7.
Score: 0.003
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Feingold KR, Staprans I, Memon RA, Moser AH, Shigenaga JK, Doerrler W, Dinarello CA, Grunfeld C. Endotoxin rapidly induces changes in lipid metabolism that produce hypertriglyceridemia: low doses stimulate hepatic triglyceride production while high doses inhibit clearance. J Lipid Res. 1992 Dec; 33(12):1765-76.
Score: 0.003
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Feingold KR, Soued M, Adi S, Staprans I, Neese R, Shigenaga J, Doerrler W, Moser A, Dinarello CA, Grunfeld C. Effect of interleukin-1 on lipid metabolism in the rat. Similarities to and differences from tumor necrosis factor. Arterioscler Thromb. 1991 May-Jun; 11(3):495-500.
Score: 0.003
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Koenig JI, Snow K, Clark BD, Toni R, Cannon JG, Shaw AR, Dinarello CA, Reichlin S, Lee SL, Lechan RM. Intrinsic pituitary interleukin-1 beta is induced by bacterial lipopolysaccharide. Endocrinology. 1990 Jun; 126(6):3053-8.
Score: 0.003
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Wogensen LD, Kolb-Bachofen V, Christensen P, Dinarello CA, Mandrup-Poulsen T, Martin S, Nerup J. Functional and morphological effects of interleukin-1 beta on the perfused rat pancreas. Diabetologia. 1990 Jan; 33(1):15-23.
Score: 0.003
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Flores EA, Bistrian BR, Pomposelli JJ, Dinarello CA, Blackburn GL, Istfan NW. Infusion of tumor necrosis factor/cachectin promotes muscle catabolism in the rat. A synergistic effect with interleukin 1. J Clin Invest. 1989 May; 83(5):1614-22.
Score: 0.002
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Flores EA, Drabik M, Gauldie J, Blackburn GL, Dinarello CA, Bistrian BR. Leukocyte endogenous mediator fails to alter protein dynamics in a model of liver dysfunction. J Lab Clin Med. 1989 Feb; 113(2):211-20.
Score: 0.002
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White CW, Ghezzi P, McMahon S, Dinarello CA, Repine JE. Cytokines increase rat lung antioxidant enzymes during exposure to hyperoxia. J Appl Physiol (1985). 1989 Feb; 66(2):1003-7.
Score: 0.002
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Scarborough DE, Lee SL, Dinarello CA, Reichlin S. Interleukin-1 beta stimulates somatostatin biosynthesis in primary cultures of fetal rat brain. Endocrinology. 1989 Jan; 124(1):549-51.
Score: 0.002
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Kaplan E, Dinarello CA, Gelfand JA. Interleukin-1 and the response to injury. Immunol Res. 1989; 8(2):118-29.
Score: 0.002
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Beasley D, Dinarello CA, Cannon JG. Interleukin-1 induces natriuresis in conscious rats: role of renal prostaglandins. Kidney Int. 1988 Jun; 33(6):1059-65.
Score: 0.002
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Domer FR, Mori K, Dinarello CA, Sokoloff L. Effects of leukocytic pyrogen (interleukin-1) on local cerebral glucose utilization in rats with and without premedication with indomethacin or dexamethasone. J Cereb Blood Flow Metab. 1988 Apr; 8(2):173-8.
Score: 0.002
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Wogensen LD, Mandrup-Poulsen T, Markholst H, Mølvig J, Lernmark A, Holst JJ, Dinarello CA, Nerup J. Interleukin-1 potentiates glucose stimulated insulin release in the isolated perfused pancreas. Acta Endocrinol (Copenh). 1988 Mar; 117(3):302-6.
Score: 0.002
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Mandrup-Poulsen T, Bendtzen K, Dinarello CA, Nerup J. Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity. J Immunol. 1987 Dec 15; 139(12):4077-82.
Score: 0.002
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Tocco-Bradley R, Georgieff M, Jones CT, Moldawer LL, Dinarello CA, Blackburn GL, Bistrian BR. Changes in energy expenditure and fat metabolism in rats infused with interleukin-1. Eur J Clin Invest. 1987 Dec; 17(6):504-10.
Score: 0.002
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Roh MS, Drazenovich KA, Barbose JJ, Dinarello CA, Cobb CF. Direct stimulation of the adrenal cortex by interleukin-1. Surgery. 1987 Aug; 102(2):140-6.
Score: 0.002
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Spinas GA, Hansen BS, Linde S, Kastern W, Mølvig J, Mandrup-Poulsen T, Dinarello CA, Nielsen JH, Nerup J. Interleukin 1 dose-dependently affects the biosynthesis of (pro)insulin in isolated rat islets of Langerhans. Diabetologia. 1987 Jul; 30(7):474-80.
Score: 0.002
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Mannie MD, Dinarello CA, Paterson PY. Interleukin 1 and myelin basic protein synergistically augment adoptive transfer activity of lymphocytes mediating experimental autoimmune encephalomyelitis in Lewis rats. J Immunol. 1987 Jun 15; 138(12):4229-35.
Score: 0.002
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Rustgi VK, Jones DB, Dinarello CA, Hoofnagle JH. Lymphokines and bile secretion in the rat. Liver. 1987 Jun; 7(3):149-54.
Score: 0.002
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White CW, Ghezzi P, Dinarello CA, Caldwell SA, McMurtry IF, Repine JE. Recombinant tumor necrosis factor/cachectin and interleukin 1 pretreatment decreases lung oxidized glutathione accumulation, lung injury, and mortality in rats exposed to hyperoxia. J Clin Invest. 1987 Jun; 79(6):1868-73.
Score: 0.002
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Naylor AM, Gubitz GJ, Dinarello CA, Veale WL. Central effects of vasopressin and 1-desamino-8-D-arginine vasopressin (DDAVP) on interleukin-1 fever in the rat. Brain Res. 1987 Jan 13; 401(1):173-7.
Score: 0.002
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Yodoi J, Okada M, Tagaya Y, Taniguchi Y, Teshigawara K, Kasahara T, Dinarello CA, Matsushima K, Honko T, Uchiyama T, et al. IL-2 receptor gene activation by ATL-derived factor (ADF). Adv Exp Med Biol. 1987; 213:139-48.
Score: 0.002
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Spinas GA, Mandrup-Poulsen T, Mølvig J, Baek L, Bendtzen K, Dinarello CA, Nerup J. Low concentrations of interleukin-1 stimulate and high concentrations inhibit insulin release from isolated rat islets of Langerhans. Acta Endocrinol (Copenh). 1986 Dec; 113(4):551-8.
Score: 0.002
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Bendtzen K, Mandrup-Poulsen T, Nerup J, Nielsen JH, Dinarello CA, Svenson M. Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans. Science. 1986 Jun 20; 232(4757):1545-7.
Score: 0.002
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Roh MS, Moldawer LL, Ekman LG, Dinarello CA, Bistrian BR, Jeevanandam M, Brennan MF. Stimulatory effect of interleukin-1 upon hepatic metabolism. Metabolism. 1986 May; 35(5):419-24.
Score: 0.002
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Hamawy KJ, Yamazaki K, Georgieff M, Dinarello CA, Moldawer LL, Blackburn GL, Bistrian BR. Improvements in host immunity by partially purified interleukin 1 in rats with portacaval anastomosis and splenectomy. JPEN J Parenter Enteral Nutr. 1986 Mar-Apr; 10(2):146-50.
Score: 0.002
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Valentine M, Lotz M, Dinarello CA, Carson DA, Vaughan JH. Lymphoblastoid B cell lines produce an interleukin-1-like activity that can be serologically distinct from macrophage interleukin-1. Lymphokine Res. 1986; 5(3):173-83.
Score: 0.002
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Mandrup-Poulsen T, Bendtzen K, Nerup J, Dinarello CA, Svenson M, Nielsen JH. Affinity-purified human interleukin I is cytotoxic to isolated islets of Langerhans. Diabetologia. 1986 Jan; 29(1):63-7.
Score: 0.002
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Loda M, Clowes GH, Dinarello CA, George BC, Lane B, Richardson W. Induction of hepatic protein synthesis by a peptide in blood plasma of patients with sepsis and trauma. Surgery. 1984 Aug; 96(2):204-13.
Score: 0.002
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Baracos V, Rodemann HP, Dinarello CA, Goldberg AL. Stimulation of muscle protein degradation and prostaglandin E2 release by leukocytic pyrogen (interleukin-1). A mechanism for the increased degradation of muscle proteins during fever. N Engl J Med. 1983 Mar 10; 308(10):553-8.
Score: 0.002
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Hooper DC, Steer CJ, Dinarello CA, Peacock AC. Haptoglobin and albumin synthesis in isolated rat hepatocytes. Response to potential mediators of the acute-phase reaction. Biochim Biophys Acta. 1981 Mar 26; 653(1):118-29.
Score: 0.001
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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