 Connection
Charles Dinarello to Animals
This is a "connection" page, showing publications Charles Dinarello has written about Animals.
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3.407 |
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Dinarello A, May M, Amo-Aparicio J, Azam T, Gaballa JM, Marchetti C, Tesoriere A, Ghirardo R, Redzic JS, Webber WS, Atif SM, Li S, Eisenmesser EZ, de Graaf DM, Dinarello CA. IL-38 regulates intestinal stem cell homeostasis by inducing WNT signaling and beneficial IL-1ß secretion. Proc Natl Acad Sci U S A. 2023 11 07; 120(45):e2306476120.
Score: 0.042
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Amo-Aparicio J, Daly J, Højen JF, Dinarello CA. Pharmacologic inhibition of NLRP3 reduces the levels of a-synuclein and protects dopaminergic neurons in a model of Parkinson's disease. J Neuroinflammation. 2023 Jun 22; 20(1):147.
Score: 0.041
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Dinarello A, Mills TS, Tengesdal IW, Powers NE, Azam T, Dinarello CA. Dexamethasone and OLT1177 Cooperate in the Reduction of Melanoma Growth by Inhibiting STAT3 Functions. Cells. 2023 01 12; 12(2).
Score: 0.039
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de Graaf DM, Wang RX, Amo-Aparicio J, Lee JS, Dowdell AS, Tengesdal IW, Marchetti C, Colgan SP, Joosten LAB, Dinarello CA. IL-38 Gene Deletion Worsens Murine Colitis. Front Immunol. 2022; 13:840719.
Score: 0.038
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Tengesdal IW, Dinarello A, Powers NE, Burchill MA, Joosten LAB, Marchetti C, Dinarello CA. Tumor NLRP3-Derived IL-1ß Drives the IL-6/STAT3 Axis Resulting in Sustained MDSC-Mediated Immunosuppression. Front Immunol. 2021; 12:661323.
Score: 0.036
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Cavalli G, Tengesdal IW, Gresnigt M, Nemkov T, Arts RJW, Domínguez-Andrés J, Molteni R, Stefanoni D, Cantoni E, Cassina L, Giugliano S, Schraa K, Mills TS, Pietras EM, Eisenmensser EZ, Dagna L, Boletta A, D'Alessandro A, Joosten LAB, Netea MG, Dinarello CA. The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity. Cell Rep. 2021 04 06; 35(1):108955.
Score: 0.035
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Abbate A, Toldo S, Marchetti C, Kron J, Van Tassell BW, Dinarello CA. Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease. Circ Res. 2020 04 24; 126(9):1260-1280.
Score: 0.033
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Powers NE, Swartzwelter B, Marchetti C, de Graaf DM, Lerchner A, Schlapschy M, Datar R, Binder U, Edwards CK, Skerra A, Dinarello CA. PASylation of IL-1 receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis. J Biol Chem. 2020 01 17; 295(3):868-882.
Score: 0.032
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Højen JF, Kristensen MLV, McKee AS, Wade MT, Azam T, Lunding LP, de Graaf DM, Swartzwelter BJ, Wegmann M, Tolstrup M, Beckman K, Fujita M, Fischer S, Dinarello CA. IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease. Nat Immunol. 2019 09; 20(9):1138-1149.
Score: 0.031
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Li S, Amo-Aparicio J, Neff CP, Tengesdal IW, Azam T, Palmer BE, López-Vales R, Bufler P, Dinarello CA. Role for nuclear interleukin-37 in the suppression of innate immunity. Proc Natl Acad Sci U S A. 2019 03 05; 116(10):4456-4461.
Score: 0.030
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Ballak DB, Li S, Cavalli G, Stahl JL, Tengesdal IW, van Diepen JA, Klück V, Swartzwelter B, Azam T, Tack CJ, Stienstra R, Mandrup-Poulsen T, Seals DR, Dinarello CA. Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue. J Biol Chem. 2018 09 14; 293(37):14224-14236.
Score: 0.029
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Dinarello CA, Kaplanski G. Indeed, IL-18 is more than an inducer of IFN-?. J Leukoc Biol. 2018 08; 104(2):237-238.
Score: 0.028
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Marchetti C, Swartzwelter B, Gamboni F, Neff CP, Richter K, Azam T, Carta S, Tengesdal I, Nemkov T, D'Alessandro A, Henry C, Jones GS, Goodrich SA, St Laurent JP, Jones TM, Scribner CL, Barrow RB, Altman RD, Skouras DB, Gattorno M, Grau V, Janciauskiene S, Rubartelli A, Joosten LAB, Dinarello CA. OLT1177, a ß-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation. Proc Natl Acad Sci U S A. 2018 02 13; 115(7):E1530-E1539.
Score: 0.028
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van de Veerdonk FL, de Graaf DM, Joosten LA, Dinarello CA. Biology of IL-38 and its role in disease. Immunol Rev. 2018 01; 281(1):191-196.
Score: 0.028
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Cavalli G, Dinarello CA. Suppression of inflammation and acquired immunity by IL-37. Immunol Rev. 2018 01; 281(1):179-190.
Score: 0.028
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Dinarello CA. Overview of the IL-1 family in innate inflammation and acquired immunity. Immunol Rev. 2018 01; 281(1):8-27.
Score: 0.028
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Dinarello CA. Introduction to the interleukin-1 family of cytokines and receptors: Drivers of innate inflammation and acquired immunity. Immunol Rev. 2018 01; 281(1):5-7.
Score: 0.028
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Cavalli G, Justice JN, Boyle KE, D'Alessandro A, Eisenmesser EZ, Herrera JJ, Hansen KC, Nemkov T, Stienstra R, Garlanda C, Mantovani A, Seals DR, Dagna L, Joosten LA, Ballak DB, Dinarello CA. Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance. Proc Natl Acad Sci U S A. 2017 02 28; 114(9):2313-2318.
Score: 0.026
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Cavalli G, Koenders M, Kalabokis V, Kim J, Tan AC, Garlanda C, Mantovani A, Dagna L, Joosten LA, Dinarello CA. Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation. Rheumatology (Oxford). 2016 Dec; 55(12):2220-2229.
Score: 0.025
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Dinarello CA, Nold-Petry C, Nold M, Fujita M, Li S, Kim S, Bufler P. Suppression of innate inflammation and immunity by interleukin-37. Eur J Immunol. 2016 05; 46(5):1067-81.
Score: 0.025
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Joosten LA, Crisan TO, Azam T, Cleophas MC, Koenders MI, van de Veerdonk FL, Netea MG, Kim S, Dinarello CA. Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1ß and by the induction of endogenous IL-1Ra. Ann Rheum Dis. 2016 06; 75(6):1219-27.
Score: 0.023
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Li S, Neff CP, Barber K, Hong J, Luo Y, Azam T, Palmer BE, Fujita M, Garlanda C, Mantovani A, Kim S, Dinarello CA. Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8. Proc Natl Acad Sci U S A. 2015 Feb 24; 112(8):2497-502.
Score: 0.023
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Dinarello CA. An expanding role for interleukin-1 blockade from gout to cancer. Mol Med. 2014 Dec 16; 20 Suppl 1:S43-58.
Score: 0.023
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Li S, Fossati G, Marchetti C, Modena D, Pozzi P, Reznikov LL, Moras ML, Azam T, Abbate A, Mascagni P, Dinarello CA. Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivo. J Biol Chem. 2015 Jan 23; 290(4):2368-78.
Score: 0.022
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van de Veerdonk FL, Dinarello CA. Deficient autophagy unravels the ROS paradox in chronic granulomatous disease. Autophagy. 2014 Jun; 10(6):1141-2.
Score: 0.022
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Dinarello CA, Bufler P. Interleukin-37. Semin Immunol. 2013 Dec 15; 25(6):466-8.
Score: 0.021
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Joosten LA, Netea MG, Dinarello CA. Interleukin-1ß in innate inflammation, autophagy and immunity. Semin Immunol. 2013 Dec 15; 25(6):416-24.
Score: 0.021
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Novick D, Kim S, Kaplanski G, Dinarello CA. Interleukin-18, more than a Th1 cytokine. Semin Immunol. 2013 Dec 15; 25(6):439-48.
Score: 0.021
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Dinarello CA. Keep up the heat on IL-1. Blood. 2012 Sep 27; 120(13):2538-9.
Score: 0.019
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Dinarello CA, Simon A, van der Meer JW. Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases. Nat Rev Drug Discov. 2012 Aug; 11(8):633-52.
Score: 0.019
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Dinarello CA. Membrane interleukin-18 revisits membrane IL-1a in T-helper type 1 responses. Eur J Immunol. 2012 Jun; 42(6):1385-7.
Score: 0.019
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Rubartelli A, Gattorno M, Netea MG, Dinarello CA. Interplay between redox status and inflammasome activation. Trends Immunol. 2011 Dec; 32(12):559-66.
Score: 0.018
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Boraschi D, Lucchesi D, Hainzl S, Leitner M, Maier E, Mangelberger D, Oostingh GJ, Pfaller T, Pixner C, Posselt G, Italiani P, Nold MF, Nold-Petry CA, Bufler P, Dinarello CA. IL-37: a new anti-inflammatory cytokine of the IL-1 family. Eur Cytokine Netw. 2011 Sep; 22(3):127-47.
Score: 0.018
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Dinarello CA. A clinical perspective of IL-1ß as the gatekeeper of inflammation. Eur J Immunol. 2011 May; 41(5):1203-17.
Score: 0.018
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Matalon S, Rasmussen TA, Dinarello CA. Histone deacetylase inhibitors for purging HIV-1 from the latent reservoir. Mol Med. 2011 May-Jun; 17(5-6):466-72.
Score: 0.017
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Dinarello CA. Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. Blood. 2011 Apr 07; 117(14):3720-32.
Score: 0.017
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Dinarello C, Arend W, Sims J, Smith D, Blumberg H, O'Neill L, Goldbach-Mansky R, Pizarro T, Hoffman H, Bufler P, Nold M, Ghezzi P, Mantovani A, Garlanda C, Boraschi D, Rubartelli A, Netea M, van der Meer J, Joosten L, Mandrup-Poulsen T, Donath M, Lewis E, Pfeilschifter J, Martin M, Kracht M, Muehl H, Novick D, Lukic M, Conti B, Solinger A, Kelk P, Peyman K, van de Veerdonk F, Gabel C. IL-1 family nomenclature. Nat Immunol. 2010 Nov; 11(11):973.
Score: 0.017
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Nold MF, Nold-Petry CA, Zepp JA, Palmer BE, Bufler P, Dinarello CA. IL-37 is a fundamental inhibitor of innate immunity. Nat Immunol. 2010 Nov; 11(11):1014-22.
Score: 0.017
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Dinarello CA, Donath MY, Mandrup-Poulsen T. Role of IL-1beta in type 2 diabetes. Curr Opin Endocrinol Diabetes Obes. 2010 Aug; 17(4):314-21.
Score: 0.017
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Dinarello CA. Why not treat human cancer with interleukin-1 blockade? Cancer Metastasis Rev. 2010 Jun; 29(2):317-29.
Score: 0.016
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Abbate A, Van Tassell BW, Seropian IM, Toldo S, Robati R, Varma A, Salloum FN, Smithson L, Dinarello CA. Interleukin-1beta modulation using a genetically engineered antibody prevents adverse cardiac remodelling following acute myocardial infarction in the mouse. Eur J Heart Fail. 2010 Apr; 12(4):319-22.
Score: 0.016
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Dinarello CA. Anti-inflammatory Agents: Present and Future. Cell. 2010 Mar 19; 140(6):935-50.
Score: 0.016
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Dinarello CA. IL-1: discoveries, controversies and future directions. Eur J Immunol. 2010 Mar; 40(3):599-606.
Score: 0.016
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Nold-Petry CA, Nold MF, Nielsen JW, Bustamante A, Zepp JA, Storm KA, Hong JW, Kim SH, Dinarello CA. Increased cytokine production in interleukin-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling. J Biol Chem. 2009 Sep 18; 284(38):25900-11.
Score: 0.015
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Olson JL, Courtney RJ, Rouhani B, Mandava N, Dinarello CA. Intravitreal anakinra inhibits choroidal neovascular membrane growth in a rat model. Ocul Immunol Inflamm. 2009 May-Jun; 17(3):195-200.
Score: 0.015
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Dinarello CA. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol. 2009; 27:519-50.
Score: 0.015
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Netea MG, Nold-Petry CA, Nold MF, Joosten LA, Opitz B, van der Meer JH, van de Veerdonk FL, Ferwerda G, Heinhuis B, Devesa I, Funk CJ, Mason RJ, Kullberg BJ, Rubartelli A, van der Meer JW, Dinarello CA. Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages. Blood. 2009 Mar 05; 113(10):2324-35.
Score: 0.015
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Lewis EC, Mizrahi M, Toledano M, Defelice N, Wright JL, Churg A, Shapiro L, Dinarello CA. alpha1-Antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice. Proc Natl Acad Sci U S A. 2008 Oct 21; 105(42):16236-41.
Score: 0.015
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Dinarello CA. Historical insights into cytokines. Eur J Immunol. 2007 Nov; 37 Suppl 1:S34-45.
Score: 0.014
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Yoon DY, Dinarello CA. Differential effects of anti-IL-1R accessory protein antibodies on IL-1alpha or IL-1beta-induced production of PGE(2) and IL-6 from 3T3-L1 cells. J Biochem Mol Biol. 2007 Jul 31; 40(4):562-70.
Score: 0.013
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Dinarello CA. A signal for the caspase-1 inflammasome free of TLR. Immunity. 2007 Apr; 26(4):383-5.
Score: 0.013
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Dinarello CA. Interleukin-18 and the pathogenesis of inflammatory diseases. Semin Nephrol. 2007 Jan; 27(1):98-114.
Score: 0.013
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Boraschi D, Dinarello CA. IL-18 in autoimmunity: review. Eur Cytokine Netw. 2006 Dec; 17(4):224-52.
Score: 0.013
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Lewis EC, Dinarello CA. Responses of IL-18- and IL-18 receptor-deficient pancreatic islets with convergence of positive and negative signals for the IL-18 receptor. Proc Natl Acad Sci U S A. 2006 Nov 07; 103(45):16852-7.
Score: 0.013
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Edwards CK, Bendele AM, Reznikov LI, Fantuzzi G, Chlipala ES, Li L, Moldawer LL, Mountz JD, Li YY, Dinarello CA. Soluble human p55 and p75 tumor necrosis factor receptors reverse spontaneous arthritis in transgenic mice expressing transmembrane tumor necrosis factor alpha. Arthritis Rheum. 2006 Sep; 54(9):2872-85.
Score: 0.013
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Vidal-Vanaclocha F, Mendoza L, Telleria N, Salado C, Valcárcel M, Gallot N, Carrascal T, Egilegor E, Beaskoetxea J, Dinarello CA. Clinical and experimental approaches to the pathophysiology of interleukin-18 in cancer progression. Cancer Metastasis Rev. 2006 Sep; 25(3):417-34.
Score: 0.013
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Falta MT, Raza M, Nevienski CJ, Brunetti TM, Fu R, Tucker RM, Gaballa JM, Minhajuddin F, Alula KM, Dinarello A, Mack DG, Martin AK, Onyiah JC, Yarnell M, Francis P, Fry TJ, Maier LA, Fontenot AP, Dinarello CA, Atif SM. Reduced CCL/Be-specific CD4+ T cells in CCL3-deficient or peptide-MHCII CAR-T cell-treated mice. JCI Insight. 2026 Jul 22; 11(14).
Score: 0.012
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Luque M, Matic M, Heras-Garvin A, Amo-Aparicio J, Luk KC, Haindl MT, Khalil M, Skouras DB, Dinarello CA, Stefanova N. Clinically advanced NLRP3 inhibitor modulates microglial transcriptome and alleviates a-synuclein-induced progression of parkinsonism. J Neuroinflammation. 2026 Jan 31; 23(1).
Score: 0.012
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Yamauchi T, Luo Y, Menon DR, Couts K, Khan S, Goel A, Dinarello CA, Zhai Z, Fujita M. Human Alpha-1 Antitrypsin Suppresses Melanoma Growth by Promoting Tumor Differentiation and CD8+ T-Cell-Mediated Immunity. Biomolecules. 2026 Jan 12; 16(1).
Score: 0.012
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Dinarello CA. Inhibitors of histone deacetylases as anti-inflammatory drugs. Ernst Schering Res Found Workshop. 2006; (56):45-60.
Score: 0.012
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Dinarello CA. Interleukin-1beta. Crit Care Med. 2005 Dec; 33(12 Suppl):S460-2.
Score: 0.012
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Schwärzler J, Menghini P, Dinarello C, Cominelli F, Tilg H. IL-1 family of cytokines in gastrointestinal and liver disorders. Nat Rev Gastroenterol Hepatol. 2026 Jan; 23(1):29-43.
Score: 0.012
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Dinarello CA. An IL-1 family member requires caspase-1 processing and signals through the ST2 receptor. Immunity. 2005 Nov; 23(5):461-2.
Score: 0.012
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Lewis EC, Shapiro L, Bowers OJ, Dinarello CA. Alpha1-antitrypsin monotherapy prolongs islet allograft survival in mice. Proc Natl Acad Sci U S A. 2005 Aug 23; 102(34):12153-8.
Score: 0.012
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Gaballa JM, Valdez C, Mack DG, Minhajuddin F, Raza M, Mohammad TA, Martin AK, Getahun A, Dinarello CA, Fontenot AP, Atif SM. Interleukin-1 signaling and CD4+ T cells control B cell recruitment to the lungs in chronic beryllium disease. Front Immunol. 2025; 16:1479348.
Score: 0.011
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Kim SH, Han SY, Azam T, Yoon DY, Dinarello CA. Interleukin-32: a cytokine and inducer of TNFalpha. Immunity. 2005 Jan; 22(1):131-42.
Score: 0.011
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Dinarello CA. Therapeutic strategies to reduce IL-1 activity in treating local and systemic inflammation. Curr Opin Pharmacol. 2004 Aug; 4(4):378-85.
Score: 0.011
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Tengesdal IW, Banks M, Dinarello CA, Marchetti C. Screening NLRP3 drug candidates in clinical development: lessons from existing and emerging technologies. Front Immunol. 2024; 15:1422249.
Score: 0.011
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Bufler P, Gamboni-Robertson F, Azam T, Kim SH, Dinarello CA. Interleukin-1 homologues IL-1F7b and IL-18 contain functional mRNA instability elements within the coding region responsive to lipopolysaccharide. Biochem J. 2004 Jul 15; 381(Pt 2):503-10.
Score: 0.011
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Jiang L, Lunding LP, Webber WS, Beckmann K, Azam T, Falkesgaard Højen J, Amo-Aparicio J, Dinarello A, Nguyen TT, Pessara U, Parera D, Orlicky DJ, Fischer S, Wegmann M, Dinarello CA, Li S. An antibody to IL-1 receptor 7 protects mice from LPS-induced tissue and systemic inflammation. Front Immunol. 2024; 15:1427100.
Score: 0.011
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Lee JK, Kim SH, Lewis EC, Azam T, Reznikov LL, Dinarello CA. Differences in signaling pathways by IL-1beta and IL-18. Proc Natl Acad Sci U S A. 2004 Jun 08; 101(23):8815-20.
Score: 0.011
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Dinarello CA. Interleukin-18 and the treatment of rheumatoid arthritis. Rheum Dis Clin North Am. 2004 May; 30(2):417-34, ix.
Score: 0.011
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Tengesdal IW, Dinarello CA, Marchetti C. NLRP3 and cancer: Pathogenesis and therapeutic opportunities. Pharmacol Ther. 2023 11; 251:108545.
Score: 0.010
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Amo-Aparicio J, Dominguez A, Atif SM, Dinarello A, Azam T, Alula KM, Piper M, Lieu CH, Lentz RW, Leal AD, Bagby SM, Messersmith WA, Karam SD, Dinarello CA, Pitts TM, Marchetti C. Pancreatic Ductal Adenocarcinoma Cells Regulate NLRP3 Activation to Generate a Tolerogenic Microenvironment. Cancer Res Commun. 2023 09 20; 3(9):1899-1911.
Score: 0.010
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The E, Zhai Y, Yao Q, Ao L, Li S, Fullerton DA, Dinarello CA, Meng X. Recombinant IL-37 Exerts an Anti-inflammatory Effect on Human Aortic Valve Interstitial Cells through Extracellular and Intracellular Actions. Int J Biol Sci. 2023; 19(12):3908-3919.
Score: 0.010
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Dinarello CA, Fantuzzi G. Interleukin-18 and host defense against infection. J Infect Dis. 2003 Jun 15; 187 Suppl 2:S370-84.
Score: 0.010
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Dinarello CA. Anti-cytokine therapeutics and infections. Vaccine. 2003 Jun 01; 21 Suppl 2:S24-34.
Score: 0.010
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Teufel LU, Netea MG, van de Veerdonk FL, Dinarello CA, Joosten LAB, Arts RJW. Opposing Effects of Interleukin-36? and Interleukin-38 on Trained Immunity. Int J Mol Sci. 2023 Jan 24; 24(3).
Score: 0.010
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Carrascal MT, Mendoza L, Valcárcel M, Salado C, Egilegor E, Tellería N, Vidal-Vanaclocha F, Dinarello CA. Interleukin-18 binding protein reduces b16 melanoma hepatic metastasis by neutralizing adhesiveness and growth factors of sinusoidal endothelium. Cancer Res. 2003 Jan 15; 63(2):491-7.
Score: 0.010
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Dinarello CA. Setting the cytokine trap for autoimmunity. Nat Med. 2003 Jan; 9(1):20-2.
Score: 0.010
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Dinarello CA, Novick D, Rubinstein M, Lonnemann G. Interleukin 18 and interleukin 18 binding protein: possible role in immunosuppression of chronic renal failure. Blood Purif. 2003; 21(3):258-70.
Score: 0.010
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Dinarello CA. The IL-1 family and inflammatory diseases. Clin Exp Rheumatol. 2002 Sep-Oct; 20(5 Suppl 27):S1-13.
Score: 0.010
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Lonnemann N, Hosseini S, Ohm M, Geffers R, Hiller K, Dinarello CA, Korte M. IL-37 expression reduces acute and chronic neuroinflammation and rescues cognitive impairment in an Alzheimer's disease mouse model. Elife. 2022 08 30; 11.
Score: 0.010
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The E, de Graaf DM, Zhai Y, Yao Q, Ao L, Fullerton DA, Dinarello CA, Meng X. Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3. Proc Natl Acad Sci U S A. 2022 09 06; 119(36):e2202577119.
Score: 0.010
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Lee E, Redzic JS, Nemkov T, Saviola AJ, Dzieciatkowska M, Hansen KC, D'Alessandro A, Dinarello C, Eisenmesser EZ. Human and Bacterial Toll-Interleukin Receptor Domains Exhibit Distinct Dynamic Features and Functions. Molecules. 2022 Jul 14; 27(14).
Score: 0.010
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Gatti S, Beck J, Fantuzzi G, Bartfai T, Dinarello CA. Effect of interleukin-18 on mouse core body temperature. Am J Physiol Regul Integr Comp Physiol. 2002 Mar; 282(3):R702-9.
Score: 0.009
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van de Veerdonk FL, Renga G, Pariano M, Bellet MM, Servillo G, Fallarino F, De Luca A, Iannitti RG, Piobbico D, Gargaro M, Manni G, D'Onofrio F, Stincardini C, Sforna L, Borghi M, Castelli M, Pieroni S, Oikonomou V, Villella VR, Puccetti M, Giovagnoli S, Galarini R, Barola C, Maiuri L, Della Fazia MA, Cellini B, Talesa VN, Dinarello CA, Costantini C, Romani L. Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy. J Clin Invest. 2022 01 18; 132(2).
Score: 0.009
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Dinarello CA. Anti-cytokine therapies in response to systemic infection. J Investig Dermatol Symp Proc. 2001 Dec; 6(3):244-50.
Score: 0.009
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Lunding LP, Skouras DB, Vock C, Dinarello CA, Wegmann M. The NLRP3 inflammasome inhibitor, OLT1177® , ameliorates experimental allergic asthma in mice. Allergy. 2022 03; 77(3):1035-1038.
Score: 0.009
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Siegmund B, Lehr HA, Fantuzzi G, Dinarello CA. IL-1 beta -converting enzyme (caspase-1) in intestinal inflammation. Proc Natl Acad Sci U S A. 2001 Nov 06; 98(23):13249-54.
Score: 0.009
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Amo-Aparicio J, Garcia-Garcia J, Puigdomenech M, Francos-Quijorna I, Skouras DB, Dinarello CA, Lopez-Vales R. Inhibition of the NLRP3 inflammasome by OLT1177 induces functional protection and myelin preservation after spinal cord injury. Exp Neurol. 2022 01; 347:113889.
Score: 0.009
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Schröder A, Lunding LP, Zissler UM, Vock C, Webering S, Ehlers JC, Orinska Z, Chaker A, Schmidt-Weber CB, Lang NJ, Schiller HB, Mall MA, Fehrenbach H, Dinarello CA, Wegmann M. IL-37 regulates allergic inflammation by counterbalancing pro-inflammatory IL-1 and IL-33. Allergy. 2022 03; 77(3):856-869.
Score: 0.009
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Javan H, Li L, Schaaf CL, Lee YS, Salama ME, Dinarello CA, Selzman CH. Interleukin-1 Receptor Antagonism Abrogates Acute Pressure Overload-Induced Murine Heart Failure. Ann Thorac Surg. 2022 07; 114(1):98-107.
Score: 0.009
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Badii M, Gaal OI, Cleophas MC, Klück V, Davar R, Habibi E, Keating ST, Novakovic B, Helsen MM, Dalbeth N, Stamp LK, Macartney-Coxson D, Phipps-Green AJ, Stunnenberg HG, Dinarello CA, Merriman TR, Netea MG, Crisan TO, Joosten LAB. Urate-induced epigenetic modifications in myeloid cells. Arthritis Res Ther. 2021 07 28; 23(1):202.
Score: 0.009
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Briukhovetska D, Dörr J, Endres S, Libby P, Dinarello CA, Kobold S. Interleukins in cancer: from biology to therapy. Nat Rev Cancer. 2021 08; 21(8):481-499.
Score: 0.009
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Kouwenberg M, Pulskens WPC, Diepeveen L, Bakker-van Bebber M, Dinarello CA, Netea MG, Hilbrands LB, van der Vlag J. Reduced CXCL1 production by endogenous IL-37 expressing dendritic cells does not affect T cell activation. PLoS One. 2021; 16(5):e0251809.
Score: 0.009
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Pizarro TT, Dinarello CA, Cominelli F. Editorial: Cytokines and Intestinal Mucosal Immunity. Front Immunol. 2021; 12:698693.
Score: 0.009
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Dinarello CA, Muegge K, Durum SK. Measurement of soluble and membrane-bound interleukin 1 using a fibroblast bioassay. Curr Protoc Immunol. 2001 May; Chapter 6:Unit 6.2.
Score: 0.009
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Tengesdal IW, Menon DR, Osborne DG, Neff CP, Powers NE, Gamboni F, Mauro AG, D'Alessandro A, Stefanoni D, Henen MA, Mills TS, De Graaf DM, Azam T, Vogeli B, Palmer BE, Pietras EM, DeGregori J, Tan AC, Joosten LAB, Fujita M, Dinarello CA, Marchetti C. Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion. Proc Natl Acad Sci U S A. 2021 03 09; 118(10).
Score: 0.009
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Mountford S, Effenberger M, Noll-Puchta H, Griessmair L, Ringleb A, Haas S, Denk G, Reiter FP, Mayr D, Dinarello CA, Tilg H, Bufler P. Modulation of Liver Inflammation and Fibrosis by Interleukin-37. Front Immunol. 2021; 12:603649.
Score: 0.009
-
Pomerantz BJ, Reznikov LL, Harken AH, Dinarello CA. Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2871-6.
Score: 0.009
-
de Graaf DM, Teufel LU, van de Veerdonk FL, Joosten LAB, Netea MG, Dinarello CA, Arts RJW. IL-38 prevents induction of trained immunity by inhibition of mTOR signaling. J Leukoc Biol. 2021 11; 110(5):907-915.
Score: 0.009
-
Hamilton JAG, Lee MY, Hunter R, Ank RS, Story JY, Talekar G, Sisroe T, Ballak DB, Fedanov A, Porter CC, Eisenmesser EZ, Dinarello CA, Raikar SS, DeGregori J, Henry CJ. Interleukin-37 improves T-cell-mediated immunity and chimeric antigen receptor T-cell therapy in aged backgrounds. Aging Cell. 2021 02; 20(2):e13309.
Score: 0.009
-
Kim SH, Reznikov LL, Stuyt RJ, Selzman CH, Fantuzzi G, Hoshino T, Young HA, Dinarello CA. Functional reconstitution and regulation of IL-18 activity by the IL-18R beta chain. J Immunol. 2001 Jan 01; 166(1):148-54.
Score: 0.009
-
Sánchez-Fernández A, Zandee S, Amo-Aparicio J, Charabati M, Prat A, Garlanda C, Eisenmesser EZ, Dinarello CA, López-Vales R. IL-37 exerts therapeutic effects in experimental autoimmune encephalomyelitis through the receptor complex IL-1R5/IL-1R8. Theranostics. 2021; 11(1):1-13.
Score: 0.009
-
Lonnemann N, Hosseini S, Marchetti C, Skouras DB, Stefanoni D, D'Alessandro A, Dinarello CA, Korte M. The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2020 12 15; 117(50):32145-32154.
Score: 0.009
-
Rønholt K, Nielsen AL, Johansen C, Vestergaard C, Fauerbye A, López-Vales R, Dinarello CA, Iversen L. IL-37 Expression Is Downregulated in Lesional Psoriasis Skin. Immunohorizons. 2020 11 25; 4(11):754-761.
Score: 0.008
-
Dinarello CA. Targeting interleukin 18 with interleukin 18 binding protein. Ann Rheum Dis. 2000 Nov; 59 Suppl 1:i17-20.
Score: 0.008
-
de Graaf DM, Maas RJA, Smeekens SP, Eisenmesser E, Redzic JS, Helsen MM, Powers NE, Li S, Kalabokis V, Gresnigt MS, Joosten LAB, Dinarello CA, van de Veerdonk FL. Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease. Cytokine. 2021 01; 137:155334.
Score: 0.008
-
Amo-Aparicio J, Sanchez-Fernandez A, Li S, Eisenmesser EZ, Garlanda C, Dinarello CA, Lopez-Vales R. Extracellular and nuclear roles of IL-37 after spinal cord injury. Brain Behav Immun. 2021 01; 91:194-201.
Score: 0.008
-
Dinarello CA. The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1. N Engl J Med. 2000 Sep 07; 343(10):732-4.
Score: 0.008
-
Dinarello CA. Interleukin-18, a proinflammatory cytokine. Eur Cytokine Netw. 2000 Sep; 11(3):483-6.
Score: 0.008
-
Vecchié A, Bonaventura A, Toldo S, Dagna L, Dinarello CA, Abbate A. IL-18 and infections: Is there a role for targeted therapies? J Cell Physiol. 2021 03; 236(3):1638-1657.
Score: 0.008
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Grander C, Schaefer B, Schwärzler J, Grabherr F, de Graaf DM, Enrich B, Oberhuber G, Mayr L, Sangineto M, Jaschke N, Adolph TE, Effenberger M, Moschen AR, Dinarello CA, Zoller H, Tilg H. Alpha-1 antitrypsin governs alcohol-related liver disease in mice and humans. Gut. 2021 03; 70(3):585-594.
Score: 0.008
-
O'Neill LA, Dinarello CA. The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense. Immunol Today. 2000 May; 21(5):206-9.
Score: 0.008
-
Netea MG, Fantuzzi G, Kullberg BJ, Stuyt RJ, Pulido EJ, McIntyre RC, Joosten LA, Van der Meer JW, Dinarello CA. Neutralization of IL-18 reduces neutrophil tissue accumulation and protects mice against lethal Escherichia coli and Salmonella typhimurium endotoxemia. J Immunol. 2000 Mar 01; 164(5):2644-9.
Score: 0.008
-
Klück V, van Deuren RC, Cavalli G, Shaukat A, Arts P, Cleophas MC, Cri?an TO, Tausche AK, Riches P, Dalbeth N, Stamp LK, Hindmarsh JH, Jansen TLTA, Janssen M, Steehouwer M, Lelieveld S, van de Vorst M, Gilissen C, Dagna L, Van de Veerdonk FL, Eisenmesser EZ, Kim S, Merriman TR, Hoischen A, Netea MG, Dinarello CA, Joosten LA. Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout. Ann Rheum Dis. 2020 04; 79(4):536-544.
Score: 0.008
-
Kim SH, Eisenstein M, Reznikov L, Fantuzzi G, Novick D, Rubinstein M, Dinarello CA. Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18. Proc Natl Acad Sci U S A. 2000 Feb 01; 97(3):1190-5.
Score: 0.008
-
Vidal-Vanaclocha F, Fantuzzi G, Mendoza L, Fuentes AM, Anasagasti MJ, Martín J, Carrascal T, Walsh P, Reznikov LL, Kim SH, Novick D, Rubinstein M, Dinarello CA. IL-18 regulates IL-1beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1. Proc Natl Acad Sci U S A. 2000 Jan 18; 97(2):734-9.
Score: 0.008
-
Reznikov LL, Shames BD, Barton HA, Selzman CH, Fantuzzi G, Kim SH, Johnson SM, Dinarello CA. Interleukin-1beta deficiency results in reduced NF-kappaB levels in pregnant mice. Am J Physiol Regul Integr Comp Physiol. 2000 Jan; 278(1):R263-70.
Score: 0.008
-
Ballak DB, Brunt VE, Sapinsley ZJ, Ziemba BP, Richey JJ, Zigler MC, Johnson LC, Gioscia-Ryan RA, Culp-Hill R, Eisenmesser EZ, D'Alessandro A, Dinarello CA, Seals DR. Short-term interleukin-37 treatment improves vascular endothelial function, endurance exercise capacity, and whole-body glucose metabolism in old mice. Aging Cell. 2020 01; 19(1):e13074.
Score: 0.008
-
Mountford S, Ringleb A, Schwaiger R, Mayr D, Kobold S, Dinarello CA, Bufler P. Interleukin-37 Inhibits Colon Carcinogensis During Chronic Colitis. Front Immunol. 2019; 10:2632.
Score: 0.008
-
Sánchez-Fernández A, Skouras DB, Dinarello CA, López-Vales R. OLT1177 (Dapansutrile), a Selective NLRP3 Inflammasome Inhibitor, Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis. Front Immunol. 2019; 10:2578.
Score: 0.008
-
Fantuzzi G, Reed DA, Dinarello CA. IL-12-induced IFN-gamma is dependent on caspase-1 processing of the IL-18 precursor. J Clin Invest. 1999 Sep; 104(6):761-7.
Score: 0.008
-
Dinarello CA. Interleukin-18. Methods. 1999 Sep; 19(1):121-32.
Score: 0.008
-
Madonna S, Girolomoni G, Dinarello CA, Albanesi C. The Significance of IL-36 Hyperactivation and IL-36R Targeting in Psoriasis. Int J Mol Sci. 2019 Jul 05; 20(13).
Score: 0.008
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Hernandez G, Mills TS, Rabe JL, Chavez JS, Kuldanek S, Kirkpatrick G, Noetzli L, Jubair WK, Zanche M, Myers JR, Stevens BM, Fleenor CJ, Adane B, Dinarello CA, Ashton J, Jordan CT, Di Paola J, Hagman JR, Holers VM, Kuhn KA, Pietras EM. Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis. Haematologica. 2020 03; 105(3):585-597.
Score: 0.008
-
Reznikov LL, Fantuzzi G, Selzman CH, Shames BD, Barton HA, Bell H, McGregor JA, Dinarello CA. Utilization of endoscopic inoculation in a mouse model of intrauterine infection-induced preterm birth: role of interleukin 1beta. Biol Reprod. 1999 May; 60(5):1231-8.
Score: 0.008
-
Mantovani A, Dinarello CA, Molgora M, Garlanda C. Interleukin-1 and Related Cytokines in the Regulation of Inflammation and Immunity. Immunity. 2019 04 16; 50(4):778-795.
Score: 0.008
-
Puren AJ, Fantuzzi G, Dinarello CA. Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cells. Proc Natl Acad Sci U S A. 1999 Mar 02; 96(5):2256-61.
Score: 0.008
-
Dinarello CA. Cytokines as endogenous pyrogens. J Infect Dis. 1999 Mar; 179 Suppl 2:S294-304.
Score: 0.008
-
Dinarello CA, Gatti S, Bartfai T. Fever: links with an ancient receptor. Curr Biol. 1999 Feb 25; 9(4):R147-50.
Score: 0.008
-
Dinarello CA. IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family. J Allergy Clin Immunol. 1999 Jan; 103(1 Pt 1):11-24.
Score: 0.007
-
Fantuzzi G, Dinarello CA. Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1). J Clin Immunol. 1999 Jan; 19(1):1-11.
Score: 0.007
-
Kaplanov I, Carmi Y, Kornetsky R, Shemesh A, Shurin GV, Shurin MR, Dinarello CA, Voronov E, Apte RN. Blocking IL-1ß reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation. Proc Natl Acad Sci U S A. 2019 01 22; 116(4):1361-1369.
Score: 0.007
-
Mercurio L, Morelli M, Scarponi C, Eisenmesser EZ, Doti N, Pagnanelli G, Gubinelli E, Mazzanti C, Cavani A, Ruvo M, Dinarello CA, Albanesi C, Madonna S. IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment. Cell Death Dis. 2018 10 30; 9(11):1104.
Score: 0.007
-
Voronov E, Dinarello CA, Apte RN. Interleukin-1a as an intracellular alarmin in cancer biology. Semin Immunol. 2018 08; 38:3-14.
Score: 0.007
-
Dinarello CA. Interleukin-1 beta, interleukin-18, and the interleukin-1 beta converting enzyme. Ann N Y Acad Sci. 1998 Sep 29; 856:1-11.
Score: 0.007
-
Wade MF, Collins MK, Richards D, Mack DG, Martin AK, Dinarello CA, Fontenot AP, McKee AS. TLR9 and IL-1R1 Promote Mobilization of Pulmonary Dendritic Cells during Beryllium Sensitization. J Immunol. 2018 10 15; 201(8):2232-2243.
Score: 0.007
-
Marchetti C, Swartzwelter B, Koenders MI, Azam T, Tengesdal IW, Powers N, de Graaf DM, Dinarello CA, Joosten LAB. NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of acute arthritis. Arthritis Res Ther. 2018 08 03; 20(1):169.
Score: 0.007
-
Kuipers EN, van Dam AD, Ballak DB, de Wit EA, Dinarello CA, Stienstra R, van Diepen JA, Rensen PCN, Boon MR. IL-37 Expression Reduces Lean Body Mass in Mice by Reducing Food Intake. Int J Mol Sci. 2018 Aug 02; 19(8).
Score: 0.007
-
Dinarello CA, Novick D, Puren AJ, Fantuzzi G, Shapiro L, Mühl H, Yoon DY, Reznikov LL, Kim SH, Rubinstein M. Overview of interleukin-18: more than an interferon-gamma inducing factor. J Leukoc Biol. 1998 Jun; 63(6):658-64.
Score: 0.007
-
Gomes RS, Silva MVT, Dos Santos JC, van Linge C, Reis JM, Teixeira MM, Pinto SA, Dorta ML, Bai X, Chan ED, Dinarello CA, Oliveira MAP, Joosten LAB, Ribeiro-Dias F. Human Interleukin-32? Plays a Protective Role in an Experimental Model of Visceral Leishmaniasis in Mice. Infect Immun. 2018 05; 86(5).
Score: 0.007
-
Yoon DY, Dinarello CA. Antibodies to domains II and III of the IL-1 receptor accessory protein inhibit IL-1 beta activity but not binding: regulation of IL-1 responses is via type I receptor, not the accessory protein. J Immunol. 1998 Apr 01; 160(7):3170-9.
Score: 0.007
-
Fantuzzi G, Puren AJ, Harding MW, Livingston DJ, Dinarello CA. Interleukin-18 regulation of interferon gamma production and cell proliferation as shown in interleukin-1beta-converting enzyme (caspase-1)-deficient mice. Blood. 1998 Mar 15; 91(6):2118-25.
Score: 0.007
-
Fantuzzi G, Dinarello CA. Stem cell factor-deficient mice have a dysregulation of cytokine production during local inflammation. Eur Cytokine Netw. 1998 Mar; 9(1):85-92.
Score: 0.007
-
Jeong MY, Lin YH, Wennersten SA, Demos-Davies KM, Cavasin MA, Mahaffey JH, Monzani V, Saripalli C, Mascagni P, Reece TB, Ambardekar AV, Granzier HL, Dinarello CA, McKinsey TA. Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism. Sci Transl Med. 2018 02 07; 10(427).
Score: 0.007
-
Dinarello CA. Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist. Int Rev Immunol. 1998; 16(5-6):457-99.
Score: 0.007
-
Grabherr F, Grander C, Adolph TE, Wieser V, Mayr L, Enrich B, Macheiner S, Sangineto M, Reiter A, Viveiros A, Zoller H, Bufler P, Moschen AR, Dinarello CA, Tilg H. Ethanol-mediated suppression of IL-37 licenses alcoholic liver disease. Liver Int. 2018 06; 38(6):1095-1101.
Score: 0.007
-
Dinarello CA. Interleukin-1. Cytokine Growth Factor Rev. 1997 Dec; 8(4):253-65.
Score: 0.007
-
Mühl H, Dinarello CA. Macrophage inflammatory protein-1 alpha production in lipopolysaccharide-stimulated human adherent blood mononuclear cells is inhibited by the nitric oxide synthase inhibitor N(G)-monomethyl-L-arginine. J Immunol. 1997 Nov 15; 159(10):5063-9.
Score: 0.007
-
Dinarello CA. Blocking interleukin-1 and tumor necrosis factor in disease. Eur Cytokine Netw. 1997 Sep; 8(3):294-6.
Score: 0.007
-
Hoeke G, Khedoe PPSJ, van Diepen JA, Pike-Overzet K, van de Ven B, Vazirpanah N, Mol I, Hiemstra PS, Staal FJT, Stienstra R, Netea MG, Dinarello CA, Rensen PCN, Berbée JFP. The Effects of Selective Hematopoietic Expression of Human IL-37 on Systemic Inflammation and Atherosclerosis in LDLr-Deficient Mice. Int J Mol Sci. 2017 Aug 09; 18(8).
Score: 0.007
-
Gomes RS, Silva MVT, Dos Santos JC, de Lima Silva LL, Batista AC, Machado JR, Teixeira MM, Dorta ML, de Oliveira MAP, Dinarello CA, Joosten LAB, Ribeiro-Dias F. IL-32? promotes the healing of murine cutaneous lesions caused by Leishmania braziliensis infection in contrast to Leishmania amazonensis. Parasit Vectors. 2017 Jul 14; 10(1):336.
Score: 0.007
-
Damen MSMA, Popa CD, Netea MG, Dinarello CA, Joosten LAB. Interleukin-32 in chronic inflammatory conditions is associated with a higher risk of cardiovascular diseases. Atherosclerosis. 2017 Sep; 264:83-91.
Score: 0.007
-
Fantuzzi G, Sacco S, Ghezzi P, Dinarello CA. Physiological and cytokine responses in IL-1 beta-deficient mice after zymosan-induced inflammation. Am J Physiol. 1997 Jul; 273(1 Pt 2):R400-6.
Score: 0.007
-
Dinarello CA. Role of pro- and anti-inflammatory cytokines during inflammation: experimental and clinical findings. J Biol Regul Homeost Agents. 1997 Jul-Sep; 11(3):91-103.
Score: 0.007
-
Schauer AE, Klassert TE, von Lachner C, Riebold D, Schneeweiß A, Stock M, Müller MM, Hammerschmidt S, Bufler P, Seifert U, Dietert K, Dinarello CA, Nold MF, Gruber AD, Nold-Petry CA, Slevogt H. IL-37 Causes Excessive Inflammation and Tissue Damage in Murine Pneumococcal Pneumonia. J Innate Immun. 2017; 9(4):403-418.
Score: 0.007
-
Neudecker V, Haneklaus M, Jensen O, Khailova L, Masterson JC, Tye H, Biette K, Jedlicka P, Brodsky KS, Gerich ME, Mack M, Robertson AAB, Cooper MA, Furuta GT, Dinarello CA, O'Neill LA, Eltzschig HK, Masters SL, McNamee EN. Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome. J Exp Med. 2017 06 05; 214(6):1737-1752.
Score: 0.007
-
Crisan TO, Cleophas MCP, Novakovic B, Erler K, van de Veerdonk FL, Stunnenberg HG, Netea MG, Dinarello CA, Joosten LAB. Uric acid priming in human monocytes is driven by the AKT-PRAS40 autophagy pathway. Proc Natl Acad Sci U S A. 2017 05 23; 114(21):5485-5490.
Score: 0.007
-
Needell JC, Dinarello CA, Ir D, Robertson CE, Ryan SM, Kroehl ME, Frank DN, Zipris D. Implication of the intestinal microbiome as a potential surrogate marker of immune responsiveness to experimental therapies in autoimmune diabetes. PLoS One. 2017; 12(3):e0173968.
Score: 0.007
-
Zhai Z, Liu W, Kaur M, Luo Y, Domenico J, Samson JM, Shellman YG, Norris DA, Dinarello CA, Spritz RA, Fujita M. NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing apoptosis in metastatic melanoma. Oncogene. 2017 07 06; 36(27):3820-3830.
Score: 0.007
-
Maicas N, van der Vlag J, Bublitz J, Florquin S, Bakker-van Bebber M, Dinarello CA, Verweij V, Masereeuw R, Joosten LA, Hilbrands LB. Human Alpha-1-Antitrypsin (hAAT) therapy reduces renal dysfunction and acute tubular necrosis in a murine model of bilateral kidney ischemia-reperfusion injury. PLoS One. 2017; 12(2):e0168981.
Score: 0.007
-
Li J, Zhai Y, Ao L, Hui H, Fullerton DA, Dinarello CA, Meng X. Interleukin-37 suppresses the inflammatory response to protect cardiac function in old endotoxemic mice. Cytokine. 2017 07; 95:55-63.
Score: 0.007
-
Davegårdh C, Broholm C, Perfilyev A, Henriksen T, García-Calzón S, Peijs L, Hansen NS, Volkov P, Kjøbsted R, Wojtaszewski JF, Pedersen M, Pedersen BK, Ballak DB, Dinarello CA, Heinhuis B, Joosten LA, Nilsson E, Vaag A, Scheele C, Ling C. Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects. BMC Med. 2017 02 22; 15(1):39.
Score: 0.007
-
Fantuzzi G, Ku G, Harding MW, Livingston DJ, Sipe JD, Kuida K, Flavell RA, Dinarello CA. Response to local inflammation of IL-1 beta-converting enzyme- deficient mice. J Immunol. 1997 Feb 15; 158(4):1818-24.
Score: 0.007
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Rider P, Voronov E, Dinarello CA, Apte RN, Cohen I. Alarmins: Feel the Stress. J Immunol. 2017 02 15; 198(4):1395-1402.
Score: 0.007
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Zeng Q, Song R, Fullerton DA, Ao L, Zhai Y, Li S, Ballak DB, Cleveland JC, Reece TB, McKinsey TA, Xu D, Dinarello CA, Meng X. Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice. Proc Natl Acad Sci U S A. 2017 02 14; 114(7):1631-1636.
Score: 0.007
-
Roerink ME, van der Schaaf ME, Dinarello CA, Knoop H, van der Meer JW. Interleukin-1 as a mediator of fatigue in disease: a narrative review. J Neuroinflammation. 2017 01 21; 14(1):16.
Score: 0.007
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Clark BD, Ikejima T, Mancilla J, Orencole SF, Sirko SP, Ishii N, Okuda K, Dinarello CA. An antibody to a 17 amino acid synthetic peptide of the type I interleukin-1 receptor preferentially blocks interleukin-1 beta binding. J Interferon Cytokine Res. 1996 Dec; 16(12):1079-88.
Score: 0.006
-
Ter Horst R, Jaeger M, Smeekens SP, Oosting M, Swertz MA, Li Y, Kumar V, Diavatopoulos DA, Jansen AFM, Lemmers H, Toenhake-Dijkstra H, van Herwaarden AE, Janssen M, van der Molen RG, Joosten I, Sweep FCGJ, Smit JW, Netea-Maier RT, Koenders MMJF, Xavier RJ, van der Meer JWM, Dinarello CA, Pavelka N, Wijmenga C, Notebaart RA, Joosten LAB, Netea MG. Host and Environmental Factors Influencing Individual Human Cytokine Responses. Cell. 2016 11 03; 167(4):1111-1124.e13.
Score: 0.006
-
Fantuzzi G, Zheng H, Faggioni R, Benigni F, Ghezzi P, Sipe JD, Shaw AR, Dinarello CA. Effect of endotoxin in IL-1 beta-deficient mice. J Immunol. 1996 Jul 01; 157(1):291-6.
Score: 0.006
-
Toldo S, Mauro AG, Marchetti C, Rose SW, Mezzaroma E, Van Tassell BW, Kim S, Dinarello CA, Abbate A. Recombinant Human Alpha-1 Antitrypsin-Fc Fusion Protein Reduces Mouse Myocardial Inflammatory Injury After Ischemia-Reperfusion Independent of Elastase Inhibition. J Cardiovasc Pharmacol. 2016 Jul; 68(1):27-32.
Score: 0.006
-
Toonen EJ, Mirea AM, Tack CJ, Stienstra R, Ballak DB, van Diepen JA, Hijmans A, Chavakis T, Dokter WH, Pham CT, Netea MG, Dinarello CA, Joosten LA. Activation of proteinase 3 contributes to Non-alcoholic Fatty Liver Disease (NAFLD) and insulin resistance. Mol Med. 2016 05 24; 22.
Score: 0.006
-
Fantuzzi G, Dinarello CA. The inflammatory response in interleukin-1 beta-deficient mice: comparison with other cytokine-related knock-out mice. J Leukoc Biol. 1996 Apr; 59(4):489-93.
Score: 0.006
-
Dinarello CA. Biologic basis for interleukin-1 in disease. Blood. 1996 Mar 15; 87(6):2095-147.
Score: 0.006
-
Iannitti RG, Napolioni V, Oikonomou V, De Luca A, Galosi C, Pariano M, Massi-Benedetti C, Borghi M, Puccetti M, Lucidi V, Colombo C, Fiscarelli E, Lass-Flörl C, Majo F, Cariani L, Russo M, Porcaro L, Ricciotti G, Ellemunter H, Ratclif L, De Benedictis FM, Talesa VN, Dinarello CA, van de Veerdonk FL, Romani L. IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis. Nat Commun. 2016 Mar 14; 7:10791.
Score: 0.006
-
Vidal-Vanaclocha F, Alvarez A, Asumendi A, Urcelay B, Tonino P, Dinarello CA. Interleukin 1 (IL-1)-dependent melanoma hepatic metastasis in vivo; increased endothelial adherence by IL-1-induced mannose receptors and growth factor production in vitro. J Natl Cancer Inst. 1996 Feb 21; 88(3-4):198-205.
Score: 0.006
-
Shirey KA, Lai W, Patel MC, Pletneva LM, Pang C, Kurt-Jones E, Lipsky M, Roger T, Calandra T, Tracey KJ, Al-Abed Y, Bowie AG, Fasano A, Dinarello CA, Gusovsky F, Blanco JC, Vogel SN. Novel strategies for targeting innate immune responses to influenza. Mucosal Immunol. 2016 09; 9(5):1173-82.
Score: 0.006
-
Coll-Miró M, Francos-Quijorna I, Santos-Nogueira E, Torres-Espin A, Bufler P, Dinarello CA, López-Vales R. Beneficial effects of IL-37 after spinal cord injury in mice. Proc Natl Acad Sci U S A. 2016 Feb 02; 113(5):1411-6.
Score: 0.006
-
Dinarello CA. Cytokines as mediators in the pathogenesis of septic shock. Curr Top Microbiol Immunol. 1996; 216:133-65.
Score: 0.006
-
Henry CJ, Casás-Selves M, Kim J, Zaberezhnyy V, Aghili L, Daniel AE, Jimenez L, Azam T, McNamee EN, Clambey ET, Klawitter J, Serkova NJ, Tan AC, Dinarello CA, DeGregori J. Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors. J Clin Invest. 2015 Dec; 125(12):4666-80.
Score: 0.006
-
Cohen I, Idan C, Rider P, Peleg R, Vornov E, Elena V, Tomas M, Martin T, Tudor C, Cicerone T, Wegner M, Mareike W, Brondani L, Lydia B, Freudenberg M, Marina F, Mittler G, Gerhard M, Ferrando-May E, Elisa FM, Dinarello CA, Apte RN, Ron AN, Schneider R, Robert S. IL-1a is a DNA damage sensor linking genotoxic stress signaling to sterile inflammation and innate immunity. Sci Rep. 2015 Oct 06; 5:14756.
Score: 0.006
-
Dinarello CA. Interleukin-1 and interleukin-1 receptor antagonist. Nutrition. 1995 Sep-Oct; 11(5 Suppl):492-4.
Score: 0.006
-
Borghi M, De Luca A, Puccetti M, Jaeger M, Mencacci A, Oikonomou V, Pariano M, Garlanda C, Moretti S, Bartoli A, Sobel J, van de Veerdonk FL, Dinarello CA, Netea MG, Romani L. Pathogenic NLRP3 Inflammasome Activity during Candida Infection Is Negatively Regulated by IL-22 via Activation of NLRC4 and IL-1Ra. Cell Host Microbe. 2015 Aug 12; 18(2):198-209.
Score: 0.006
-
Rider P, Carmi Y, Yossef R, Guttman O, Eini H, Azam T, Dinarello CA, Lewis EC. IL-1 Receptor Antagonist Chimeric Protein: Context-Specific and Inflammation-Restricted Activation. J Immunol. 2015 Aug 15; 195(4):1705-12.
Score: 0.006
-
Dinarello CA, Margolis NH. Cytokine-processing enzymes. Stopping the cuts. Curr Biol. 1995 Jun 01; 5(6):587-90.
Score: 0.006
-
Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, Jacobs AH, Wyss-Coray T, Vitorica J, Ransohoff RM, Herrup K, Frautschy SA, Finsen B, Brown GC, Verkhratsky A, Yamanaka K, Koistinaho J, Latz E, Halle A, Petzold GC, Town T, Morgan D, Shinohara ML, Perry VH, Holmes C, Bazan NG, Brooks DJ, Hunot S, Joseph B, Deigendesch N, Garaschuk O, Boddeke E, Dinarello CA, Breitner JC, Cole GM, Golenbock DT, Kummer MP. Neuroinflammation in Alzheimer's disease. Lancet Neurol. 2015 Apr; 14(4):388-405.
Score: 0.006
-
Bai X, Shang S, Henao-Tamayo M, Basaraba RJ, Ovrutsky AR, Matsuda JL, Takeda K, Chan MM, Dakhama A, Kinney WH, Trostel J, Bai A, Honda JR, Achcar R, Hartney J, Joosten LA, Kim SH, Orme I, Dinarello CA, Ordway DJ, Chan ED. Human IL-32 expression protects mice against a hypervirulent strain of Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2015 Apr 21; 112(16):5111-6.
Score: 0.006
-
Nold-Petry CA, Lo CY, Rudloff I, Elgass KD, Li S, Gantier MP, Lotz-Havla AS, Gersting SW, Cho SX, Lao JC, Ellisdon AM, Rotter B, Azam T, Mangan NE, Rossello FJ, Whisstock JC, Bufler P, Garlanda C, Mantovani A, Dinarello CA, Nold MF. IL-37 requires the receptors IL-18Ra and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction. Nat Immunol. 2015 Apr; 16(4):354-65.
Score: 0.006
-
Netea MG, van de Veerdonk FL, van der Meer JW, Dinarello CA, Joosten LA. Inflammasome-independent regulation of IL-1-family cytokines. Annu Rev Immunol. 2015; 33:49-77.
Score: 0.006
-
Dinarello CA. The interleukin-1 family: 10 years of discovery. FASEB J. 1994 Dec; 8(15):1314-25.
Score: 0.006
-
Bamias G, Dinarello CA, Rivera-Nieves J. Innate cytokines dictate the fate of acute intestinal inflammation. Gastroenterology. 2015 Jan; 148(1):248-50.
Score: 0.006
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Moretti S, Bozza S, Oikonomou V, Renga G, Casagrande A, Iannitti RG, Puccetti M, Garlanda C, Kim S, Li S, van de Veerdonk FL, Dinarello CA, Romani L. IL-37 inhibits inflammasome activation and disease severity in murine aspergillosis. PLoS Pathog. 2014 Nov; 10(11):e1004462.
Score: 0.006
-
Dinarello CA. The biological properties of interleukin-1. Eur Cytokine Netw. 1994 Nov-Dec; 5(6):517-31.
Score: 0.006
-
Luo Y, Cai X, Liu S, Wang S, Nold-Petry CA, Nold MF, Bufler P, Norris D, Dinarello CA, Fujita M. Suppression of antigen-specific adaptive immunity by IL-37 via induction of tolerogenic dendritic cells. Proc Natl Acad Sci U S A. 2014 Oct 21; 111(42):15178-83.
Score: 0.006
-
Marcondes AM, Karoopongse E, Lesnikova M, Margineantu D, Welte T, Dinarello CA, Hockenbery D, Janciauskiene S, Deeg HJ. a-1-Antitrypsin (AAT)-modified donor cells suppress GVHD but enhance the GVL effect: a role for mitochondrial bioenergetics. Blood. 2014 Oct 30; 124(18):2881-91.
Score: 0.006
-
Ballak DB, van Diepen JA, Moschen AR, Jansen HJ, Hijmans A, Groenhof GJ, Leenders F, Bufler P, Boekschoten MV, Müller M, Kersten S, Li S, Kim S, Eini H, Lewis EC, Joosten LA, Tilg H, Netea MG, Tack CJ, Dinarello CA, Stienstra R. IL-37 protects against obesity-induced inflammation and insulin resistance. Nat Commun. 2014 Sep 03; 5:4711.
Score: 0.006
-
Wakabayashi G, Cannon JG, Gelfand JA, Clark BD, Aiura K, Burke JF, Wolff SM, Dinarello CA. Altered interleukin-1 and tumor necrosis factor production and secretion during pyrogenic tolerance to LPS in rabbits. Am J Physiol. 1994 Jul; 267(1 Pt 2):R329-36.
Score: 0.005
-
Dinarello CA. Is there a role for interleukin-1 blockade in intravenous immunoglobulin therapy? Immunol Rev. 1994 Jun; 139:173-88.
Score: 0.005
-
Vidal-Vanaclocha F, Amézaga C, Asumendi A, Kaplanski G, Dinarello CA. Interleukin-1 receptor blockade reduces the number and size of murine B16 melanoma hepatic metastases. Cancer Res. 1994 May 15; 54(10):2667-72.
Score: 0.005
-
Gresnigt MS, Bozza S, Becker KL, Joosten LA, Abdollahi-Roodsaz S, van der Berg WB, Dinarello CA, Netea MG, Fontaine T, De Luca A, Moretti S, Romani L, Latge JP, van de Veerdonk FL. A polysaccharide virulence factor from Aspergillus fumigatus elicits anti-inflammatory effects through induction of Interleukin-1 receptor antagonist. PLoS Pathog. 2014 Mar; 10(3):e1003936.
Score: 0.005
-
de Luca A, Smeekens SP, Casagrande A, Iannitti R, Conway KL, Gresnigt MS, Begun J, Plantinga TS, Joosten LA, van der Meer JW, Chamilos G, Netea MG, Xavier RJ, Dinarello CA, Romani L, van de Veerdonk FL. IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans. Proc Natl Acad Sci U S A. 2014 Mar 04; 111(9):3526-31.
Score: 0.005
-
Toldo S, Mezzaroma E, O'Brien L, Marchetti C, Seropian IM, Voelkel NF, Van Tassell BW, Dinarello CA, Abbate A. Interleukin-18 mediates interleukin-1-induced cardiac dysfunction. Am J Physiol Heart Circ Physiol. 2014 Apr 01; 306(7):H1025-31.
Score: 0.005
-
Bulau AM, Nold MF, Li S, Nold-Petry CA, Fink M, Mansell A, Schwerd T, Hong J, Rubartelli A, Dinarello CA, Bufler P. Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses. Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7):2650-5.
Score: 0.005
-
Christensen DP, Gysemans C, Lundh M, Dahllöf MS, Noesgaard D, Schmidt SF, Mandrup S, Birkbak N, Workman CT, Piemonti L, Blaabjerg L, Monzani V, Fossati G, Mascagni P, Paraskevas S, Aikin RA, Billestrup N, Grunnet LG, Dinarello CA, Mathieu C, Mandrup-Poulsen T. Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and ß-cell protection. Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3):1055-9.
Score: 0.005
-
Dinarello CA. Blocking interleukin-1 receptors. Int J Clin Lab Res. 1994; 24(2):61-79.
Score: 0.005
-
Dinarello CA. Interleukin-1. Adv Pharmacol. 1994; 25:21-51.
Score: 0.005
-
Garlanda C, Dinarello CA, Mantovani A. The interleukin-1 family: back to the future. Immunity. 2013 Dec 12; 39(6):1003-18.
Score: 0.005
-
Nold-Petry CA, Rudloff I, Baumer Y, Ruvo M, Marasco D, Botti P, Farkas L, Cho SX, Zepp JA, Azam T, Dinkel H, Palmer BE, Boisvert WA, Cool CD, Taraseviciene-Stewart L, Heinhuis B, Joosten LA, Dinarello CA, Voelkel NF, Nold MF. IL-32 promotes angiogenesis. J Immunol. 2014 Jan 15; 192(2):589-602.
Score: 0.005
-
Dinarello CA, Cannon JG. Cytokine measurements in septic shock. Ann Intern Med. 1993 Oct 15; 119(8):853-4.
Score: 0.005
-
Cannon JG, Nerad JL, Poutsiaka DD, Dinarello CA. Measuring circulating cytokines. J Appl Physiol (1985). 1993 Oct; 75(4):1897-902.
Score: 0.005
-
Hara N, Alkanani AK, Dinarello CA, Zipris D. Modulation of virus-induced innate immunity and type 1 diabetes by IL-1 blockade. Innate Immun. 2014 Aug; 20(6):574-84.
Score: 0.005
-
Shapiro L, Zhang XX, Rupp RG, Wolff SM, Dinarello CA. Ciliary neurotrophic factor is an endogenous pyrogen. Proc Natl Acad Sci U S A. 1993 Sep 15; 90(18):8614-8.
Score: 0.005
-
Mancilla-Ramírez J, Ramírez-Herrera M, Portillo-Gómez L, Gaitán-Meza J, Dinarello CA. [Antagonists in neonatal sepsis]. Bol Med Hosp Infant Mex. 1993 Sep; 50(9):691-3.
Score: 0.005
-
Hara N, Alkanani AK, Dinarello CA, Zipris D. Histone deacetylase inhibitor suppresses virus-induced proinflammatory responses and type 1 diabetes. J Mol Med (Berl). 2014 Jan; 92(1):93-102.
Score: 0.005
-
Jonigk D, Al-Omari M, Maegel L, Müller M, Izykowski N, Hong J, Hong K, Kim SH, Dorsch M, Mahadeva R, Laenger F, Kreipe H, Braun A, Shahaf G, Lewis EC, Welte T, Dinarello CA, Janciauskiene S. Anti-inflammatory and immunomodulatory properties of a1-antitrypsin without inhibition of elastase. Proc Natl Acad Sci U S A. 2013 Sep 10; 110(37):15007-12.
Score: 0.005
-
Aiura K, Gelfand JA, Burke JF, Thompson RC, Dinarello CA. Interleukin-1 (IL-1) receptor antagonist prevents Staphylococcus epidermidis-induced hypotension and reduces circulating levels of tumor necrosis factor and IL-1 beta in rabbits. Infect Immun. 1993 Aug; 61(8):3342-50.
Score: 0.005
-
Collins CB, Aherne CM, Ehrentraut SF, Gerich ME, McNamee EN, McManus MC, Lebsack MD, Jedlicka P, Azam T, de Zoeten EF, Dinarello CA, Rivera-Nieves J. Alpha-1-antitrypsin therapy ameliorates acute colitis and chronic murine ileitis. Inflamm Bowel Dis. 2013 Aug; 19(9):1964-73.
Score: 0.005
-
Bersudsky M, Luski L, Fishman D, White RM, Ziv-Sokolovskaya N, Dotan S, Rider P, Kaplanov I, Aychek T, Dinarello CA, Apte RN, Voronov E. Non-redundant properties of IL-1a and IL-1ß during acute colon inflammation in mice. Gut. 2014 Apr; 63(4):598-609.
Score: 0.005
-
Dinarello CA. Modalities for reducing interleukin 1 activity in disease. Immunol Today. 1993 Jun; 14(6):260-4.
Score: 0.005
-
Kratzer A, Salys J, Nold-Petry C, Cool C, Zamora M, Bowler R, Koczulla AR, Janciauskiene S, Edwards MG, Dinarello CA, Taraseviciene-Stewart L. Role of IL-18 in second-hand smoke-induced emphysema. Am J Respir Cell Mol Biol. 2013 Jun; 48(6):725-32.
Score: 0.005
-
Heinhuis B, Popa CD, van Tits BL, Kim SH, Zeeuwen PL, van den Berg WB, van der Meer JW, van der Vliet JA, Stalenhoef AF, Dinarello CA, Netea MG, Joosten LA. Towards a role of interleukin-32 in atherosclerosis. Cytokine. 2013 Oct; 64(1):433-40.
Score: 0.005
-
Coceani F, Lees J, Mancilla J, Belizario J, Dinarello CA. Interleukin-6 and tumor necrosis factor in cerebrospinal fluid: changes during pyrogen fever. Brain Res. 1993 May 28; 612(1-2):165-71.
Score: 0.005
-
Lee S, Lee Y, Hong K, Hong J, Bae S, Choi J, Jhun H, Kwak A, Kim E, Jo S, Dinarello CA, Kim S. Effect of recombinant a1-antitrypsin Fc-fused (AAT-Fc)protein on the inhibition of inflammatory cytokine production and streptozotocin-induced diabetes. Mol Med. 2013 May 20; 19:65-71.
Score: 0.005
-
Dinarello CA. Modalities for reducing interleukin 1 activity in disease. Trends Pharmacol Sci. 1993 May; 14(5):155-9.
Score: 0.005
-
Dinarello CA, Gelfand JA, Wolff SM. Anticytokine strategies in the treatment of the systemic inflammatory response syndrome. JAMA. 1993 Apr 14; 269(14):1829-35.
Score: 0.005
-
Lupfer C, Thomas PG, Anand PK, Vogel P, Milasta S, Martinez J, Huang G, Green M, Kundu M, Chi H, Xavier RJ, Green DR, Lamkanfi M, Dinarello CA, Doherty PC, Kanneganti TD. Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection. Nat Immunol. 2013 May; 14(5):480-8.
Score: 0.005
-
Carmi Y, Dotan S, Rider P, Kaplanov I, White MR, Baron R, Abutbul S, Huszar M, Dinarello CA, Apte RN, Voronov E. The role of IL-1ß in the early tumor cell-induced angiogenic response. J Immunol. 2013 Apr 01; 190(7):3500-9.
Score: 0.005
-
Mancilla J, García P, Dinarello CA. The interleukin-1 receptor antagonist can either reduce or enhance the lethality of Klebsiella pneumoniae sepsis in newborn rats. Infect Immun. 1993 Mar; 61(3):926-32.
Score: 0.005
-
Dinarello CA, Wolff SM. The role of interleukin-1 in disease. N Engl J Med. 1993 Jan 14; 328(2):106-13.
Score: 0.005
-
Dinarello CA. Blocking interleukin-1 in disease. Blood Purif. 1993; 11(2):118-27.
Score: 0.005
-
Dahllöf MS, Christensen DP, Lundh M, Dinarello CA, Mascagni P, Grunnet LG, Mandrup-Poulsen T. The lysine deacetylase inhibitor Givinostat inhibits ß-cell IL-1ß induced IL-1ß transcription and processing. Islets. 2012 Nov-Dec; 4(6):417-22.
Score: 0.005
-
Gresnigt MS, Joosten LA, Verschueren I, van der Meer JW, Netea MG, Dinarello CA, van de Veerdonk FL. Neutrophil-mediated inhibition of proinflammatory cytokine responses. J Immunol. 2012 Nov 15; 189(10):4806-15.
Score: 0.005
-
Dinarello CA. The role of interleukin-1 in host responses to infectious diseases. Infect Agents Dis. 1992 Oct; 1(5):227-36.
Score: 0.005
-
Liu W, Luo Y, Dunn JH, Norris DA, Dinarello CA, Fujita M. Dual role of apoptosis-associated speck-like protein containing a CARD (ASC) in tumorigenesis of human melanoma. J Invest Dermatol. 2013 Feb; 133(2):518-27.
Score: 0.005
-
Heinhuis B, Netea MG, van den Berg WB, Dinarello CA, Joosten LA. Interleukin-32: a predominantly intracellular proinflammatory mediator that controls cell activation and cell death. Cytokine. 2012 Nov; 60(2):321-7.
Score: 0.005
-
Mancilla J, Ikejima T, Dinarello CA. Glycosylation of the interleukin-1 receptor type I is required for optimal binding of interleukin-1. Lymphokine Cytokine Res. 1992 Aug; 11(4):197-205.
Score: 0.005
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Lundh M, Christensen DP, Damgaard Nielsen M, Richardson SJ, Dahllöf MS, Skovgaard T, Berthelsen J, Dinarello CA, Stevenazzi A, Mascagni P, Grunnet LG, Morgan NG, Mandrup-Poulsen T. Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children. Diabetologia. 2012 Sep; 55(9):2421-31.
Score: 0.005
-
Dinarello CA. Interleukin-1 and tumor necrosis factor: effector cytokines in autoimmune diseases. Semin Immunol. 1992 Jun; 4(3):133-45.
Score: 0.005
-
Dinarello CA. Role of interleukin-1 in infectious diseases. Immunol Rev. 1992 Jun; 127:119-46.
Score: 0.005
-
Van Tassell BW, Arena RA, Toldo S, Mezzaroma E, Azam T, Seropian IM, Shah K, Canada J, Voelkel NF, Dinarello CA, Abbate A. Enhanced interleukin-1 activity contributes to exercise intolerance in patients with systolic heart failure. PLoS One. 2012; 7(3):e33438.
Score: 0.005
-
Ye K, Koch KC, Clark BD, Dinarello CA. Interleukin-1 down-regulates gene and surface expression of interleukin-1 receptor type I by destabilizing its mRNA whereas interleukin-2 increases its expression. Immunology. 1992 Mar; 75(3):427-34.
Score: 0.005
-
Dinarello CA. Reduction of inflammation by decreasing production of interleukin-1 or by specific receptor antagonism. Int J Tissue React. 1992; 14(2):65-75.
Score: 0.005
-
Koch KC, Ye K, Clark BD, Dinarello CA. Interleukin 4 (IL) 4 up-regulates gene and surface IL 1 receptor type I in murine T helper type 2 cells. Eur J Immunol. 1992 Jan; 22(1):153-7.
Score: 0.005
-
Dinarello CA. The biology of interleukin-1. Chem Immunol. 1992; 51:1-32.
Score: 0.005
-
Dinarello CA. Anti-cytokine strategies. Eur Cytokine Netw. 1992 Jan-Feb; 3(1):7-17.
Score: 0.005
-
Tawara I, Sun Y, Lewis EC, Toubai T, Evers R, Nieves E, Azam T, Dinarello CA, Reddy P. Alpha-1-antitrypsin monotherapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation. Proc Natl Acad Sci U S A. 2012 Jan 10; 109(2):564-9.
Score: 0.005
-
Berda-Haddad Y, Robert S, Salers P, Zekraoui L, Farnarier C, Dinarello CA, Dignat-George F, Kaplanski G. Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1a. Proc Natl Acad Sci U S A. 2011 Dec 20; 108(51):20684-9.
Score: 0.005
-
Dinarello CA. Inflammatory cytokines: interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases. Curr Opin Immunol. 1991 Dec; 3(6):941-8.
Score: 0.005
-
Clark BD, Bedrosian I, Schindler R, Cominelli F, Cannon JG, Shaw AR, Dinarello CA. Detection of interleukin 1 alpha and 1 beta in rabbit tissues during endotoxemia using sensitive radioimmunoassays. J Appl Physiol (1985). 1991 Dec; 71(6):2412-8.
Score: 0.005
-
Dinarello CA, Thompson RC. Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro. Immunol Today. 1991 Nov; 12(11):404-10.
Score: 0.005
-
Dinarello CA, Cannon JG, Mancilla J, Bishai I, Lees J, Coceani F. Interleukin-6 as an endogenous pyrogen: induction of prostaglandin E2 in brain but not in peripheral blood mononuclear cells. Brain Res. 1991 Oct 25; 562(2):199-206.
Score: 0.005
-
Shainheit MG, Lasocki KW, Finger E, Larkin BM, Smith PM, Sharpe AH, Dinarello CA, Rutitzky LI, Stadecker MJ. The pathogenic Th17 cell response to major schistosome egg antigen is sequentially dependent on IL-23 and IL-1ß. J Immunol. 2011 Nov 15; 187(10):5328-35.
Score: 0.005
-
Murray DR, Mummidi S, Valente AJ, Yoshida T, Somanna NK, Delafontaine P, Dinarello CA, Chandrasekar B. ß2 adrenergic activation induces the expression of IL-18 binding protein, a potent inhibitor of isoproterenol induced cardiomyocyte hypertrophy in vitro and myocardial hypertrophy in vivo. J Mol Cell Cardiol. 2012 Jan; 52(1):206-18.
Score: 0.005
-
Rider P, Carmi Y, Guttman O, Braiman A, Cohen I, Voronov E, White MR, Dinarello CA, Apte RN. IL-1a and IL-1ß recruit different myeloid cells and promote different stages of sterile inflammation. J Immunol. 2011 Nov 01; 187(9):4835-43.
Score: 0.004
-
Marcondes AM, Li X, Tabellini L, Bartenstein M, Kabacka J, Sale GE, Hansen JA, Dinarello CA, Deeg HJ. Inhibition of IL-32 activation by a-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model. Blood. 2011 Nov 03; 118(18):5031-9.
Score: 0.004
-
McNamee EN, Masterson JC, Jedlicka P, McManus M, Grenz A, Collins CB, Nold MF, Nold-Petry C, Bufler P, Dinarello CA, Rivera-Nieves J. Interleukin 37 expression protects mice from colitis. Proc Natl Acad Sci U S A. 2011 Oct 04; 108(40):16711-6.
Score: 0.004
-
Wakabayashi G, Gelfand JA, Jung WK, Connolly RJ, Burke JF, Dinarello CA. Staphylococcus epidermidis induces complement activation, tumor necrosis factor and interleukin-1, a shock-like state and tissue injury in rabbits without endotoxemia. Comparison to Escherichia coli. J Clin Invest. 1991 Jun; 87(6):1925-35.
Score: 0.004
-
Carta S, Tassi S, Pettinati I, Delfino L, Dinarello CA, Rubartelli A. The rate of interleukin-1beta secretion in different myeloid cells varies with the extent of redox response to Toll-like receptor triggering. J Biol Chem. 2011 Aug 05; 286(31):27069-80.
Score: 0.004
-
Toldo S, Seropian IM, Mezzaroma E, Van Tassell BW, Salloum FN, Lewis EC, Voelkel N, Dinarello CA, Abbate A. Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia-reperfusion injury. J Mol Cell Cardiol. 2011 Aug; 51(2):244-51.
Score: 0.004
-
Belizario JE, Dinarello CA. Interleukin 1, interleukin 6, tumor necrosis factor, and transforming growth factor beta increase cell resistance to tumor necrosis factor cytotoxicity by growth arrest in the G1 phase of the cell cycle. Cancer Res. 1991 May 01; 51(9):2379-85.
Score: 0.004
-
Dinarello CA. Interleukin-1 and interleukin-1 antagonism. Blood. 1991 Apr 15; 77(8):1627-52.
Score: 0.004
-
Wakabayashi G, Gelfand JA, Burke JF, Thompson RC, Dinarello CA. A specific receptor antagonist for interleukin 1 prevents Escherichia coli-induced shock in rabbits. FASEB J. 1991 Mar 01; 5(3):338-43.
Score: 0.004
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Kamari Y, Shaish A, Vax E, Shemesh S, Kandel-Kfir M, Arbel Y, Olteanu S, Barshack I, Dotan S, Voronov E, Dinarello CA, Apte RN, Harats D. Lack of interleukin-1a or interleukin-1ß inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice. J Hepatol. 2011 Nov; 55(5):1086-94.
Score: 0.004
-
Zepp JA, Nold-Petry CA, Dinarello CA, Nold MF. Protection from RNA and DNA viruses by IL-32. J Immunol. 2011 Apr 01; 186(7):4110-8.
Score: 0.004
-
van de Veerdonk FL, Netea MG, Dinarello CA, Joosten LA. Inflammasome activation and IL-1ß and IL-18 processing during infection. Trends Immunol. 2011 Mar; 32(3):110-6.
Score: 0.004
-
Kamari Y, Shaish A, Shemesh S, Vax E, Grosskopf I, Dotan S, White M, Voronov E, Dinarello CA, Apte RN, Harats D. Reduced atherosclerosis and inflammatory cytokines in apolipoprotein-E-deficient mice lacking bone marrow-derived interleukin-1a. Biochem Biophys Res Commun. 2011 Feb 11; 405(2):197-203.
Score: 0.004
-
Lewis EC, Blaabjerg L, Størling J, Ronn SG, Mascagni P, Dinarello CA, Mandrup-Poulsen T. The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet ß cells in vivo and in vitro. Mol Med. 2011 May-Jun; 17(5-6):369-77.
Score: 0.004
-
Elkabets M, Ribeiro VS, Dinarello CA, Ostrand-Rosenberg S, Di Santo JP, Apte RN, Vosshenrich CA. IL-1ß regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function. Eur J Immunol. 2010 Dec; 40(12):3347-57.
Score: 0.004
-
Choi J, Bae S, Hong J, Ryoo S, Jhun H, Hong K, Yoon D, Lee S, Her E, Choi W, Kim J, Azam T, Dinarello CA, Kim S. Paradoxical effects of constitutive human IL-32{gamma} in transgenic mice during experimental colitis. Proc Natl Acad Sci U S A. 2010 Dec 07; 107(49):21082-6.
Score: 0.004
-
Joosten LA, Van De Veerdonk FL, Vonk AG, Boerman OC, Keuter M, Fantuzzi G, Verschueren I, Van Der Poll T, Dinarello CA, Kullberg BJ, Van Der Meer JW, Netea MG. Differential susceptibility to lethal endotoxaemia in mice deficient in IL-1a, IL-1ß or IL-1 receptor type I. APMIS. 2010 Dec; 118(12):1000-7.
Score: 0.004
-
Lundh M, Christensen DP, Rasmussen DN, Mascagni P, Dinarello CA, Billestrup N, Grunnet LG, Mandrup-Poulsen T. Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines. Diabetologia. 2010 Dec; 53(12):2569-78.
Score: 0.004
-
Ikejima T, Okusawa S, Ghezzi P, van der Meer JW, Dinarello CA. Interleukin-1 induces tumor necrosis factor (TNF) in human peripheral blood mononuclear cells in vitro and a circulating TNF-like activity in rabbits. J Infect Dis. 1990 Jul; 162(1):215-23.
Score: 0.004
-
Maier B, Ogihara T, Trace AP, Tersey SA, Robbins RD, Chakrabarti SK, Nunemaker CS, Stull ND, Taylor CA, Thompson JE, Dondero RS, Lewis EC, Dinarello CA, Nadler JL, Mirmira RG. The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice. J Clin Invest. 2010 Jun; 120(6):2156-70.
Score: 0.004
-
Heinhuis B, Koenders MI, van de Loo FA, van Lent PL, Kim SH, Dinarello CA, Joosten LA, van den Berg WB. IL-32gamma and Streptococcus pyogenes cell wall fragments synergise for IL-1-dependent destructive arthritis via upregulation of TLR-2 and NOD2. Ann Rheum Dis. 2010 Oct; 69(10):1866-72.
Score: 0.004
-
Dinarello CA, Clark BD, Ikejima T, Puren AJ, Savage N, Rosoff PM. Interleukin 1 receptors and biological responses. Yale J Biol Med. 1990 Mar-Apr; 63(2):87-93.
Score: 0.004
-
Cohen I, Rider P, Carmi Y, Braiman A, Dotan S, White MR, Voronov E, Martin MU, Dinarello CA, Apte RN. Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation. Proc Natl Acad Sci U S A. 2010 Feb 09; 107(6):2574-9.
Score: 0.004
-
Dinarello CA, Endres S, Meydani SN, Meydani M, Hellerstein MK. Interleukin-1, anorexia, and dietary fatty acids. Ann N Y Acad Sci. 1990; 587:332-8.
Score: 0.004
-
Dinarello CA, Schindler R. Dissociation of transcription from translation of human IL-1-beta: the induction of steady state mRNA by adherence or recombinant C5a in the absence of translation. Prog Clin Biol Res. 1990; 349:195-204.
Score: 0.004
-
Dinarello CA. The pathophysiology of the pro-inflammatory cytokines. Biotherapy. 1990; 2(3):189-91.
Score: 0.004
-
Joosten LA, Netea MG, Fantuzzi G, Koenders MI, Helsen MM, Sparrer H, Pham CT, van der Meer JW, Dinarello CA, van den Berg WB. Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta. Arthritis Rheum. 2009 Dec; 60(12):3651-62.
Score: 0.004
-
Dinarello CA. The endogenous pyrogens in host-defense interactions. Hosp Pract (Off Ed). 1989 Nov 15; 24(11):111-5, 118, 121 passim.
Score: 0.004
-
Orencole SF, Dinarello CA. Characterization of a subclone (D10S) of the D10.G4.1 helper T-cell line which proliferates to attomolar concentrations of interleukin-1 in the absence of mitogens. Cytokine. 1989 Nov; 1(1):14-22.
Score: 0.004
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Savage N, Puren AJ, Orencole SF, Ikejima T, Clark BD, Dinarello CA. Studies on IL-1 receptors on D10S T-helper cells: demonstration of two molecularly and antigenically distinct IL-1 binding proteins. Cytokine. 1989 Nov; 1(1):23-35.
Score: 0.004
-
Hong J, Bae S, Kang Y, Yoon D, Bai X, Chan ED, Azam T, Dinarello CA, Lee S, Her E, Rho G, Kim S. Suppressing IL-32 in monocytes impairs the induction of the proinflammatory cytokines TNFalpha and IL-1beta. Cytokine. 2010 Feb; 49(2):171-6.
Score: 0.004
-
Wang M, Tan J, Wang Y, Meldrum KK, Dinarello CA, Meldrum DR. IL-18 binding protein-expressing mesenchymal stem cells improve myocardial protection after ischemia or infarction. Proc Natl Acad Sci U S A. 2009 Oct 13; 106(41):17499-504.
Score: 0.004
-
Carmi Y, Voronov E, Dotan S, Lahat N, Rahat MA, Fogel M, Huszar M, White MR, Dinarello CA, Apte RN. The role of macrophage-derived IL-1 in induction and maintenance of angiogenesis. J Immunol. 2009 Oct 01; 183(7):4705-14.
Score: 0.004
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Shein NA, Grigoriadis N, Alexandrovich AG, Simeonidou C, Lourbopoulos A, Polyzoidou E, Trembovler V, Mascagni P, Dinarello CA, Shohami E. Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury. FASEB J. 2009 Dec; 23(12):4266-75.
Score: 0.004
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Favilli F, Anzilotti C, Martinelli L, Quattroni P, De Martino S, Pratesi F, Neumann D, Beermann S, Novick D, Dinarello CA, Boraschi D, Migliorini P. IL-18 activity in systemic lupus erythematosus. Ann N Y Acad Sci. 2009 Sep; 1173:301-9.
Score: 0.004
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Kliger Y, Levy O, Oren A, Ashkenazy H, Tiran Z, Novik A, Rosenberg A, Amir A, Wool A, Toporik A, Schreiber E, Eshel D, Levine Z, Cohen Y, Nold-Petry C, Dinarello CA, Borukhov I. Peptides modulating conformational changes in secreted chaperones: from in silico design to preclinical proof of concept. Proc Natl Acad Sci U S A. 2009 Aug 18; 106(33):13797-801.
Score: 0.004
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Fibbe WE, van der Meer JW, Falkenburg JH, Hamilton MS, Kluin PM, Dinarello CA. A single low dose of human recombinant interleukin 1 accelerates the recovery of neutrophils in mice with cyclophosphamide-induced neutropenia. Exp Hematol. 1989 Aug; 17(7):805-8.
Score: 0.004
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Kleinnijenhuis J, Joosten LA, van de Veerdonk FL, Savage N, van Crevel R, Kullberg BJ, van der Ven A, Ottenhoff TH, Dinarello CA, van der Meer JW, Netea MG. Transcriptional and inflammasome-mediated pathways for the induction of IL-1beta production by Mycobacterium tuberculosis. Eur J Immunol. 2009 Jul; 39(7):1914-22.
Score: 0.004
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Hellerstein MK, Meydani SN, Meydani M, Wu K, Dinarello CA. Interleukin-1-induced anorexia in the rat. Influence of prostaglandins. J Clin Invest. 1989 Jul; 84(1):228-35.
Score: 0.004
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Bani-Hani AH, Leslie JA, Asanuma H, Dinarello CA, Campbell MT, Meldrum DR, Zhang H, Hile K, Meldrum KK. IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis. Kidney Int. 2009 Sep; 76(5):500-11.
Score: 0.004
-
Sun Y, Chin YE, Weisiger E, Malter C, Tawara I, Toubai T, Gatza E, Mascagni P, Dinarello CA, Reddy P. Cutting edge: Negative regulation of dendritic cells through acetylation of the nonhistone protein STAT-3. J Immunol. 2009 May 15; 182(10):5899-903.
Score: 0.004
-
Elkabets M, Krelin Y, Dotan S, Cerwenka A, Porgador A, Lichtenstein RG, White MR, Zoller M, Iwakura Y, Dinarello CA, Voronov E, Apte RN. Host-derived interleukin-1alpha is important in determining the immunogenicity of 3-methylcholantrene tumor cells. J Immunol. 2009 Apr 15; 182(8):4874-81.
Score: 0.004
-
Ben-Sasson SZ, Hu-Li J, Quiel J, Cauchetaux S, Ratner M, Shapira I, Dinarello CA, Paul WE. IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation. Proc Natl Acad Sci U S A. 2009 Apr 28; 106(17):7119-24.
Score: 0.004
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van de Veerdonk FL, Joosten LA, Devesa I, Mora-Montes HM, Kanneganti TD, Dinarello CA, van der Meer JW, Gow NA, Kullberg BJ, Netea MG. Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans. J Infect Dis. 2009 Apr 01; 199(7):1087-96.
Score: 0.004
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Dinarello CA, Okusawa S, Gelfand JA. Interleukin-1 induces a shock-like state in rabbits: synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition. Prog Clin Biol Res. 1989; 286:243-63.
Score: 0.004
-
Dinarello CA. Interleukin-1 and the effects of cyclooxygenase inhibitors on its biological activities. Bull N Y Acad Med. 1989 Jan; 65(1):80-92.
Score: 0.004
-
Dinarello CA, Savage N. Interleukin-1 and its receptor. Crit Rev Immunol. 1989; 9(1):1-20.
Score: 0.004
-
Dinarello CA, Orencole SF, Savage N. Interleukin-1 induced T-lymphocyte proliferation and its relation to IL-1 receptors. Adv Exp Med Biol. 1989; 254:45-53.
Score: 0.004
-
van der Meer JW, Rubin RH, Pasternack M, Medearis DN, Lynch P, Dinarello CA. The in vivo and in vitro effects of interleukin-1 and tumor necrosis factor on murine cytomegalovirus infection. Biotherapy. 1989; 1(3):227-31.
Score: 0.004
-
Dinarello CA, Neta R. An overview on interleukin-1 as a therapeutic agent. Biotherapy. 1989; 1(4):245-54.
Score: 0.004
-
Cominelli F, Dinarello CA. Interleukin-1 in the pathogenesis of and protection from inflammatory bowel disease. Biotherapy. 1989; 1(4):369-75.
Score: 0.004
-
Dinarello CA, Okusawa S, Gelfand JA. Interleukin-1 induces a shock-like state in rabbits: synergism with tumor necrosis factor and the effect of ibuprofen. Prog Clin Biol Res. 1989; 299:203-15.
Score: 0.004
-
Endres S, Ghorbani R, Lonnemann G, van der Meer JW, Dinarello CA. Measurement of immunoreactive interleukin-1 beta from human mononuclear cells: optimization of recovery, intrasubject consistency, and comparison with interleukin-1 alpha and tumor necrosis factor. Clin Immunol Immunopathol. 1988 Dec; 49(3):424-38.
Score: 0.004
-
Schweizer A, Feige U, Fontana A, Müller K, Dinarello CA. Interleukin-1 enhances pain reflexes. Mediation through increased prostaglandin E2 levels. Agents Actions. 1988 Dec; 25(3-4):246-51.
Score: 0.004
-
Ikejima T, Okusawa S, van der Meer JW, Dinarello CA. Induction by toxic-shock-syndrome toxin-1 of a circulating tumor necrosis factor-like substance in rabbits and of immunoreactive tumor necrosis factor and interleukin-1 from human mononuclear cells. J Infect Dis. 1988 Nov; 158(5):1017-25.
Score: 0.004
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Mier JW, Vachino G, van der Meer JW, Numerof RP, Adams S, Cannon JG, Bernheim HA, Atkins MB, Parkinson DR, Dinarello CA. Induction of circulating tumor necrosis factor (TNF alpha) as the mechanism for the febrile response to interleukin-2 (IL-2) in cancer patients. J Clin Immunol. 1988 Nov; 8(6):426-36.
Score: 0.004
-
Moore CC, Martin EN, Lee G, Taylor C, Dondero R, Reznikov LL, Dinarello C, Thompson J, Scheld WM. Eukaryotic translation initiation factor 5A small interference RNA-liposome complexes reduce inflammation and increase survival in murine models of severe sepsis and acute lung injury. J Infect Dis. 2008 Nov 01; 198(9):1407-14.
Score: 0.004
-
Bosisio D, Vulcano M, Del Prete A, Sironi M, Salvi V, Salogni L, Riboldi E, Leoni F, Dinarello CA, Girolomoni G, Sozzani S. Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo. J Leukoc Biol. 2008 Dec; 84(6):1540-8.
Score: 0.004
-
Choi JD, Bae SY, Hong JW, Azam T, Dinarello CA, Her E, Choi WS, Kim BK, Lee CK, Yoon DY, Kim SJ, Kim SH. Identification of the most active interleukin-32 isoform. Immunology. 2009 Apr; 126(4):535-42.
Score: 0.004
-
He Z, Lu L, Altmann C, Hoke TS, Ljubanovic D, Jani A, Dinarello CA, Faubel S, Edelstein CL. Interleukin-18 binding protein transgenic mice are protected against ischemic acute kidney injury. Am J Physiol Renal Physiol. 2008 Nov; 295(5):F1414-21.
Score: 0.004
-
Reddy P, Sun Y, Toubai T, Duran-Struuck R, Clouthier SG, Weisiger E, Maeda Y, Tawara I, Krijanovski O, Gatza E, Liu C, Malter C, Mascagni P, Dinarello CA, Ferrara JL. Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase-dependent DC functions and regulates experimental graft-versus-host disease in mice. J Clin Invest. 2008 Jul; 118(7):2562-73.
Score: 0.004
-
Van't Wout JW, Van der Meer JW, Barza M, Dinarello CA. Protection of neutropenic mice from lethal Candida albicans infection by recombinant interleukin 1. Eur J Immunol. 1988 Jul; 18(7):1143-6.
Score: 0.004
-
Sennello JA, Fayad R, Pini M, Gove ME, Ponemone V, Cabay RJ, Siegmund B, Dinarello CA, Fantuzzi G. Interleukin-18, together with interleukin-12, induces severe acute pancreatitis in obese but not in nonobese leptin-deficient mice. Proc Natl Acad Sci U S A. 2008 Jun 10; 105(23):8085-90.
Score: 0.004
-
Cha J, Wang Z, Ao L, Zou N, Dinarello CA, Banerjee A, Fullerton DA, Meng X. Cytokines link Toll-like receptor 4 signaling to cardiac dysfunction after global myocardial ischemia. Ann Thorac Surg. 2008 May; 85(5):1678-85.
Score: 0.004
-
Coceani F, Lees J, Dinarello CA. Occurrence of interleukin-1 in cerebrospinal fluid of the conscious cat. Brain Res. 1988 Apr 19; 446(2):245-50.
Score: 0.004
-
Okusawa S, Gelfand JA, Ikejima T, Connolly RJ, Dinarello CA. Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition. J Clin Invest. 1988 Apr; 81(4):1162-72.
Score: 0.004
-
van der Meer JW, Barza M, Wolff SM, Dinarello CA. A low dose of recombinant interleukin 1 protects granulocytopenic mice from lethal gram-negative infection. Proc Natl Acad Sci U S A. 1988 Mar; 85(5):1620-3.
Score: 0.004
-
Dinarello CA. Interleukin-1. Dig Dis Sci. 1988 Mar; 33(3 Suppl):25S-35S.
Score: 0.004
-
van der Meer JW, Endres S, Lonnemann G, Cannon JG, Ikejima T, Okusawa S, Gelfand JA, Dinarello CA. Concentrations of immunoreactive human tumor necrosis factor alpha produced by human mononuclear cells in vitro. J Leukoc Biol. 1988 Mar; 43(3):216-23.
Score: 0.004
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Kim KH, Shim JH, Seo EH, Cho MC, Kang JW, Kim SH, Yu DY, Song EY, Lee HG, Sohn JH, Kim J, Dinarello CA, Yoon DY. Interleukin-32 monoclonal antibodies for immunohistochemistry, Western blotting, and ELISA. J Immunol Methods. 2008 Apr 20; 333(1-2):38-50.
Score: 0.003
-
Glauben R, Batra A, Stroh T, Erben U, Fedke I, Lehr HA, Leoni F, Mascagni P, Dinarello CA, Zeitz M, Siegmund B. Histone deacetylases: novel targets for prevention of colitis-associated cancer in mice. Gut. 2008 May; 57(5):613-22.
Score: 0.003
-
Dinarello CA, Cannon JG, Wolff SM. New concepts on the pathogenesis of fever. Rev Infect Dis. 1988 Jan-Feb; 10(1):168-89.
Score: 0.003
-
Dinarello CA. Interleukin-1. Ann N Y Acad Sci. 1988; 546:122-32.
Score: 0.003
-
Dinarello CA. Endogenous pyrogens. Methods Enzymol. 1988; 163:495-510.
Score: 0.003
-
Dinarello CA. Interleukin-1--its multiple biological effects and its association with hemodialysis. Blood Purif. 1988; 6(3):164-72.
Score: 0.003
-
Dinarello CA. The biology of interleukin 1 and comparison to tumor necrosis factor. Immunol Lett. 1987 Dec; 16(3-4):227-31.
Score: 0.003
-
Movat HZ, Burrowes CE, Cybulsky MI, Dinarello CA. Acute inflammation and a Shwartzman-like reaction induced by interleukin-1 and tumor necrosis factor. Synergistic action of the cytokines in the induction of inflammation and microvascular injury. Am J Pathol. 1987 Dec; 129(3):463-76.
Score: 0.003
-
Manzer R, Dinarello CA, McConville G, Mason RJ. Ozone exposure of macrophages induces an alveolar epithelial chemokine response through IL-1alpha. Am J Respir Cell Mol Biol. 2008 Mar; 38(3):318-23.
Score: 0.003
-
Dinarello CA, Ikejima T, Warner SJ, Orencole SF, Lonnemann G, Cannon JG, Libby P. Interleukin 1 induces interleukin 1. I. Induction of circulating interleukin 1 in rabbits in vivo and in human mononuclear cells in vitro. J Immunol. 1987 Sep 15; 139(6):1902-10.
Score: 0.003
-
Lorenzo JA, Sousa SL, Alander C, Raisz LG, Dinarello CA. Comparison of the bone-resorbing activity in the supernatants from phytohemagglutinin-stimulated human peripheral blood mononuclear cells with that of cytokines through the use of an antiserum to interleukin 1. Endocrinology. 1987 Sep; 121(3):1164-70.
Score: 0.003
-
Lavi G, Voronov E, Dinarello CA, Apte RN, Cohen S. Sustained delivery of IL-1 Ra from biodegradable microspheres reduces the number of murine B16 melanoma lung metastases. J Control Release. 2007 Nov 06; 123(2):123-30.
Score: 0.003
-
Ao L, Song Y, Fullerton DA, Dinarello CA, Meng X. The interaction between myocardial depressant factors in endotoxemic cardiac dysfunction: role of TNF-alpha in TLR4-mediated ICAM-1 expression. Cytokine. 2007 Jun; 38(3):124-9.
Score: 0.003
-
Cybulsky MI, Movat HZ, Dinarello CA. Role of interleukin-1 and tumour necrosis factor-alpha in acute inflammation. Ann Inst Pasteur Immunol. 1987 May-Jun; 138(3):505-12.
Score: 0.003
-
Mandrup-Poulsen T, Egeberg J, Nerup J, Bendtzen K, Nielsen JH, Dinarello CA. Ultrastructural studies of time-course and cellular specificity of interleukin-1 mediated islet cytotoxicity. Acta Pathol Microbiol Immunol Scand C. 1987 Apr; 95(2):55-63.
Score: 0.003
-
Faubel S, Lewis EC, Reznikov L, Ljubanovic D, Hoke TS, Somerset H, Oh DJ, Lu L, Klein CL, Dinarello CA, Edelstein CL. Cisplatin-induced acute renal failure is associated with an increase in the cytokines interleukin (IL)-1beta, IL-18, IL-6, and neutrophil infiltration in the kidney. J Pharmacol Exp Ther. 2007 Jul; 322(1):8-15.
Score: 0.003
-
Hurgin V, Novick D, Werman A, Dinarello CA, Rubinstein M. Antiviral and immunoregulatory activities of IFN-gamma depend on constitutively expressed IL-1alpha. Proc Natl Acad Sci U S A. 2007 Mar 20; 104(12):5044-9.
Score: 0.003
-
Krelin Y, Voronov E, Dotan S, Elkabets M, Reich E, Fogel M, Huszar M, Iwakura Y, Segal S, Dinarello CA, Apte RN. Interleukin-1beta-driven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors. Cancer Res. 2007 Feb 01; 67(3):1062-71.
Score: 0.003
-
Gauldie J, Sauder DN, McAdam KP, Dinarello CA. Purified interleukin-1 (IL-1) from human monocytes stimulates acute-phase protein synthesis by rodent hepatocytes in vitro. Immunology. 1987 Feb; 60(2):203-7.
Score: 0.003
-
Larsen L, Tonnesen M, Ronn SG, Størling J, Jørgensen S, Mascagni P, Dinarello CA, Billestrup N, Mandrup-Poulsen T. Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells. Diabetologia. 2007 Apr; 50(4):779-89.
Score: 0.003
-
Edelstein CL, Hoke TS, Somerset H, Fang W, Klein CL, Dinarello CA, Faubel S. Proximal tubules from caspase-1-deficient mice are protected against hypoxia-induced membrane injury. Nephrol Dial Transplant. 2007 Apr; 22(4):1052-61.
Score: 0.003
-
Schnyder J, Payne T, Dinarello CA. Human monocyte or recombinant interleukin 1's are specific for the secretion of a metalloproteinase from chondrocytes. J Immunol. 1987 Jan 15; 138(2):496-503.
Score: 0.003
-
Dinarello CA. Interleukin-1: multiple biological properties and mechanisms of action. Adv Prostaglandin Thromboxane Leukot Res. 1987; 17B:900-4.
Score: 0.003
-
Del Rey A, Besedovsky H, Sorkin E, Dinarello CA. Interleukin-1 and glucocorticoid hormones integrate an immunoregulatory feedback circuit. Ann N Y Acad Sci. 1987; 496:85-90.
Score: 0.003
-
Lisi PJ, Chu CW, Koch GA, Endres S, Lonnemann G, Dinarello CA. Development and use of a radioimmunoassay for human interleukin-1 beta. Lymphokine Res. 1987; 6(3):229-44.
Score: 0.003
-
Dinarello CA. The multiple biological properties of interleukin-1 influencing immunocompetent cells. Adv Exp Med Biol. 1987; 213:103-14.
Score: 0.003
-
Movat HZ, Cybulsky MI, Colditz IG, Chan MK, Dinarello CA. Acute inflammation in gram-negative infection: endotoxin, interleukin 1, tumor necrosis factor, and neutrophils. Fed Proc. 1987 Jan; 46(1):97-104.
Score: 0.003
-
Meldrum KK, Misseri R, Metcalfe P, Dinarello CA, Hile KL, Meldrum DR. TNF-alpha neutralization ameliorates obstruction-induced renal fibrosis and dysfunction. Am J Physiol Regul Integr Comp Physiol. 2007 Apr; 292(4):R1456-64.
Score: 0.003
-
Kamari Y, Werman-Venkert R, Shaish A, Werman A, Harari A, Gonen A, Voronov E, Grosskopf I, Sharabi Y, Grossman E, Iwakura Y, Dinarello CA, Apte RN, Harats D. Differential role and tissue specificity of interleukin-1alpha gene expression in atherogenesis and lipid metabolism. Atherosclerosis. 2007 Nov; 195(1):31-8.
Score: 0.003
-
Ghezzi P, Saccardo B, Villa P, Rossi V, Bianchi M, Dinarello CA. Role of interleukin-1 in the depression of liver drug metabolism by endotoxin. Infect Immun. 1986 Dec; 54(3):837-40.
Score: 0.003
-
Cannon JG, Tatro JB, Reichlin S, Dinarello CA. Alpha melanocyte stimulating hormone inhibits immunostimulatory and inflammatory actions of interleukin 1. J Immunol. 1986 Oct 01; 137(7):2232-6.
Score: 0.003
-
Dinarello CA. Multiple biological properties of recombinant human interleukin 1 (beta). Immunobiology. 1986 Sep; 172(3-5):301-15.
Score: 0.003
-
Besedovsky H, del Rey A, Sorkin E, Dinarello CA. Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones. Science. 1986 Aug 08; 233(4764):652-4.
Score: 0.003
-
Conti P, Cifone MG, Alesse E, Reale M, Fieschi C, Dinarello CA. In vitro enhanced thromboxane B2 release by polymorphonuclear leukocytes and macrophages after treatment with human recombinant interleukin 1. Prostaglandins. 1986 Jul; 32(1):111-5.
Score: 0.003
-
Dinarello CA, Cannon JG, Wolff SM, Bernheim HA, Beutler B, Cerami A, Figari IS, Palladino MA, O'Connor JV. Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1. J Exp Med. 1986 Jun 01; 163(6):1433-50.
Score: 0.003
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Dinarello CA, Cannon JG, Mier JW, Bernheim HA, LoPreste G, Lynn DL, Love RN, Webb AC, Auron PE, Reuben RC, et al. Multiple biological activities of human recombinant interleukin 1. J Clin Invest. 1986 Jun; 77(6):1734-9.
Score: 0.003
-
Netea MG, Joosten LA, Lewis E, Jensen DR, Voshol PJ, Kullberg BJ, Tack CJ, van Krieken H, Kim SH, Stalenhoef AF, van de Loo FA, Verschueren I, Pulawa L, Akira S, Eckel RH, Dinarello CA, van den Berg W, van der Meer JW. Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance. Nat Med. 2006 Jun; 12(6):650-6.
Score: 0.003
-
Dvorkin T, Song X, Argov S, White RM, Zoller M, Segal S, Dinarello CA, Voronov E, Apte RN. Immune phenomena involved in the in vivo regression of fibrosarcoma cells expressing cell-associated IL-1alpha. J Leukoc Biol. 2006 Jul; 80(1):96-106.
Score: 0.003
-
Glauben R, Batra A, Fedke I, Zeitz M, Lehr HA, Leoni F, Mascagni P, Fantuzzi G, Dinarello CA, Siegmund B. Histone hyperacetylation is associated with amelioration of experimental colitis in mice. J Immunol. 2006 Apr 15; 176(8):5015-22.
Score: 0.003
-
Morris AM, Sennello JA, Fayad RA, Eckel RH, Dinarello CA, Fantuzzi G. T cell-mediated hepatic inflammation modulates adiponectin levels in mice: role of tumor necrosis factor alpha. Metabolism. 2006 Apr; 55(4):555-9.
Score: 0.003
-
Joosten LA, Netea MG, Kim SH, Yoon DY, Oppers-Walgreen B, Radstake TR, Barrera P, van de Loo FA, Dinarello CA, van den Berg WB. IL-32, a proinflammatory cytokine in rheumatoid arthritis. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3298-303.
Score: 0.003
-
Novick D, Rubinstein M, Azam T, Rabinkov A, Dinarello CA, Kim SH. Proteinase 3 is an IL-32 binding protein. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3316-21.
Score: 0.003
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Dayer JM, de Rochemonteix B, Burrus B, Demczuk S, Dinarello CA. Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells. J Clin Invest. 1986 Feb; 77(2):645-8.
Score: 0.003
-
Dinarello CA. Studies on the biological properties of purified and recombinant human interleukin-1. Methods Find Exp Clin Pharmacol. 1986 Feb; 8(2):57-61.
Score: 0.003
-
Dinarello CA, Mier JW. Interleukins. Annu Rev Med. 1986; 37:173-8.
Score: 0.003
-
Song X, Krelin Y, Dvorkin T, Bjorkdahl O, Segal S, Dinarello CA, Voronov E, Apte RN. CD11b+/Gr-1+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1beta-secreting cells. J Immunol. 2005 Dec 15; 175(12):8200-8.
Score: 0.003
-
Portnoy J, Pan T, Dinarello CA, Shannon JM, Westcott JY, Zhang L, Mason RJ. Alveolar type II cells inhibit fibroblast proliferation: role of IL-1alpha. Am J Physiol Lung Cell Mol Physiol. 2006 Feb; 290(2):L307-16.
Score: 0.003
-
Clarke JH, Cha JY, Walsh MD, Gamboni-Robertson F, Banerjee A, Reznikov LL, Dinarello CA, Harken AH, McCarter MD. Melanoma inhibits macrophage activation by suppressing toll-like receptor 4 signaling. J Am Coll Surg. 2005 Sep; 201(3):418-25.
Score: 0.003
-
Dinarello CA. An update on human interleukin-1: from molecular biology to clinical relevance. J Clin Immunol. 1985 Sep; 5(5):287-97.
Score: 0.003
-
Jones-Carson J, Fantuzzi G, Siegmund B, Dinarello C, Tracey KJ, Wang H, Fang FC, Vazquez-Torres A. Suppressor alphabeta T lymphocytes control innate resistance to endotoxic shock. J Infect Dis. 2005 Sep 15; 192(6):1039-46.
Score: 0.003
-
Fayad R, Sennello JA, Kim SH, Pini M, Dinarello CA, Fantuzzi G. Induction of thymocyte apoptosis by systemic administration of concanavalin A in mice: role of TNF-alpha, IFN-gamma and glucocorticoids. Eur J Immunol. 2005 Aug; 35(8):2304-12.
Score: 0.003
-
Cannon JG, Dinarello CA. Increased plasma interleukin-1 activity in women after ovulation. Science. 1985 Mar 08; 227(4691):1247-9.
Score: 0.003
-
Bernheim HA, Dinarello CA. Effect of protein synthesis inhibitors on leukocytic pyrogen-induced in vitro hypothalamic prostaglandin production. Yale J Biol Med. 1985 Mar-Apr; 58(2):179-87.
Score: 0.003
-
Libby P, Wyler DJ, Janicka MW, Dinarello CA. Differential effects of human interleukin-1 on growth of human fibroblasts and vascular smooth muscle cells. Arteriosclerosis. 1985 Mar-Apr; 5(2):186-91.
Score: 0.003
-
Mier JW, Souza LM, Allegretta M, Boone T, Bernheim HA, Dinarello CA. Dissimilarities between purified human interleukin-1 and recombinant human interleukin-2 in the induction of fever, brain prostaglandin, and acute-phase protein synthesis. J Biol Response Mod. 1985 Feb; 4(1):35-45.
Score: 0.003
-
Sennello JA, Fayad R, Morris AM, Eckel RH, Asilmaz E, Montez J, Friedman JM, Dinarello CA, Fantuzzi G. Regulation of T cell-mediated hepatic inflammation by adiponectin and leptin. Endocrinology. 2005 May; 146(5):2157-64.
Score: 0.003
-
Wang W, Faubel S, Ljubanovic D, Mitra A, Falk SA, Kim J, Tao Y, Soloviev A, Reznikov LL, Dinarello CA, Schrier RW, Edelstein CL. Endotoxemic acute renal failure is attenuated in caspase-1-deficient mice. Am J Physiol Renal Physiol. 2005 May; 288(5):F997-1004.
Score: 0.003
-
Stuyt RJ, Netea MG, Verschueren I, Dinarello CA, Kullberg BJ, van der Meer JW. Interleukin-18 does not modulate the acute-phase response. J Endotoxin Res. 2005; 11(2):85-8.
Score: 0.003
-
Leoni F, Fossati G, Lewis EC, Lee JK, Porro G, Pagani P, Modena D, Moras ML, Pozzi P, Reznikov LL, Siegmund B, Fantuzzi G, Dinarello CA, Mascagni P. The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines in vitro and systemic inflammation in vivo. Mol Med. 2005 Jan-Dec; 11(1-12):1-15.
Score: 0.003
-
Faubel S, Ljubanovic D, Reznikov L, Somerset H, Dinarello CA, Edelstein CL. Caspase-1-deficient mice are protected against cisplatin-induced apoptosis and acute tubular necrosis. Kidney Int. 2004 Dec; 66(6):2202-13.
Score: 0.003
-
Lee HG, Kim H, Oh WK, Yu KA, Choe YK, Ahn JS, Kim DS, Kim SH, Dinarello CA, Kim K, Yoon DY. Tetramethoxy hydroxyflavone p7F downregulates inflammatory mediators via the inhibition of nuclear factor kappaB. Ann N Y Acad Sci. 2004 Dec; 1030:555-68.
Score: 0.003
-
Auron PE, Webb AC, Rosenwasser LJ, Mucci SF, Rich A, Wolff SM, Dinarello CA. Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. Proc Natl Acad Sci U S A. 1984 Dec; 81(24):7907-11.
Score: 0.003
-
Misseri R, Meldrum DR, Dinarello CA, Dagher P, Hile KL, Rink RC, Meldrum KK. TNF-alpha mediates obstruction-induced renal tubular cell apoptosis and proapoptotic signaling. Am J Physiol Renal Physiol. 2005 Feb; 288(2):F406-11.
Score: 0.003
-
Siegmund B, Sennello JA, Lehr HA, Senaldi G, Dinarello CA, Fantuzzi G. Frontline: interferon regulatory factor-1 as a protective gene in intestinal inflammation: role of TCR gamma delta T cells and interleukin-18-binding protein. Eur J Immunol. 2004 Sep; 34(9):2356-64.
Score: 0.003
-
Dinarello CA, Bernheim HA, Duff GW, Le HV, Nagabhushan TL, Hamilton NC, Coceani F. Mechanisms of fever induced by recombinant human interferon. J Clin Invest. 1984 Sep; 74(3):906-13.
Score: 0.003
-
Dinarello CA, Clowes GH, Gordon AH, Saravis CA, Wolff SM. Cleavage of human interleukin 1: isolation of a peptide fragment from plasma of febrile humans and activated monocytes. J Immunol. 1984 Sep; 133(3):1332-8.
Score: 0.003
-
Netea MG, Kullberg BJ, Jacobs LE, Verver-Jansen TJ, van der Ven-Jongekrijg J, Galama JM, Stalenhoef AF, Dinarello CA, Van der Meer JW. Chlamydia pneumoniae stimulates IFN-gamma synthesis through MyD88-dependent, TLR2- and TLR4-independent induction of IL-18 release. J Immunol. 2004 Jul 15; 173(2):1477-82.
Score: 0.003
-
Goldberg AL, Baracos V, Rodemann P, Waxman L, Dinarello C. Control of protein degradation in muscle by prostaglandins, Ca2+, and leukocytic pyrogen (interleukin 1). Fed Proc. 1984 Apr; 43(5):1301-6.
Score: 0.003
-
Schottelius AJ, Moldawer LL, Dinarello CA, Asadullah K, Sterry W, Edwards CK. Biology of tumor necrosis factor-alpha- implications for psoriasis. Exp Dermatol. 2004 Apr; 13(4):193-222.
Score: 0.003
-
Reddy P, Maeda Y, Hotary K, Liu C, Reznikov LL, Dinarello CA, Ferrara JL. Histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces acute graft-versus-host disease and preserves graft-versus-leukemia effect. Proc Natl Acad Sci U S A. 2004 Mar 16; 101(11):3921-6.
Score: 0.003
-
Werman A, Werman-Venkert R, White R, Lee JK, Werman B, Krelin Y, Voronov E, Dinarello CA, Apte RN. The precursor form of IL-1alpha is an intracrine proinflammatory activator of transcription. Proc Natl Acad Sci U S A. 2004 Feb 24; 101(8):2434-9.
Score: 0.003
-
Wang M, Sankula R, Tsai BM, Meldrum KK, Turrentine M, March KL, Brown JW, Dinarello CA, Meldrum DR. P38 MAPK mediates myocardial proinflammatory cytokine production and endotoxin-induced contractile suppression. Shock. 2004 Feb; 21(2):170-4.
Score: 0.003
-
Park JW, Taube C, Swasey C, Kodama T, Joetham A, Balhorn A, Takeda K, Miyahara N, Allen CB, Dakhama A, Kim SH, Dinarello CA, Gelfand EW. Interleukin-1 receptor antagonist attenuates airway hyperresponsiveness following exposure to ozone. Am J Respir Cell Mol Biol. 2004 Jun; 30(6):830-6.
Score: 0.003
-
Taube C, Nick JA, Siegmund B, Duez C, Takeda K, Rha YH, Park JW, Joetham A, Poch K, Dakhama A, Dinarello CA, Gelfand EW. Inhibition of early airway neutrophilia does not affect development of airway hyperresponsiveness. Am J Respir Cell Mol Biol. 2004 Jun; 30(6):837-43.
Score: 0.003
-
Dinarello CA. Interleukin-1. Rev Infect Dis. 1984 Jan-Feb; 6(1):51-95.
Score: 0.003
-
Dinarello CA, Bishai I, Rosenwasser LJ, Coceani F. The influence of lipoxygenase inhibitors on the in vitro production of human leukocytic pyrogen and lymphocyte activating factor (interleukin-1). Int J Immunopharmacol. 1984; 6(1):43-50.
Score: 0.003
-
Dinarello CA. Interleukin 1 as mediator of the acute-phase response. Surv Immunol Res. 1984; 3(1):29-33.
Score: 0.003
-
Song X, Voronov E, Dvorkin T, Fima E, Cagnano E, Benharroch D, Shendler Y, Bjorkdahl O, Segal S, Dinarello CA, Apte RN. Differential effects of IL-1 alpha and IL-1 beta on tumorigenicity patterns and invasiveness. J Immunol. 2003 Dec 15; 171(12):6448-56.
Score: 0.003
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Bossù P, Neumann D, Del Giudice E, Ciaramella A, Gloaguen I, Fantuzzi G, Dinarello CA, Di Carlo E, Musiani P, Meroni PL, Caselli G, Ruggiero P, Boraschi D. IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease. Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24):14181-6.
Score: 0.003
-
Bar D, Apte RN, Voronov E, Dinarello CA, Cohen S. A continuous delivery system of IL-1 receptor antagonist reduces angiogenesis and inhibits tumor development. FASEB J. 2004 Jan; 18(1):161-3.
Score: 0.003
-
Rijneveld AW, Florquin S, Speelman P, Edwards CK, Dinarello CA, van der Poll T. Interleukin-1 receptor antagonist transiently impairs antibacterial defense but not survival in murine pneumococcal pneumonia. Eur Cytokine Netw. 2003 Oct-Dec; 14(4):242-5.
Score: 0.003
-
Fantuzzi G, Banda NK, Guthridge C, Vondracek A, Kim SH, Siegmund B, Azam T, Sennello JA, Dinarello CA, Arend WP. Generation and characterization of mice transgenic for human IL-18-binding protein isoform a. J Leukoc Biol. 2003 Nov; 74(5):889-96.
Score: 0.003
-
Dinarello CA. Molecular mechanisms in endotoxin fever. Agents Actions. 1983 Aug; 13(5-6):470-86.
Score: 0.003
-
Lipsky PE, Thompson PA, Rosenwasser LJ, Dinarello CA. The role of interleukin 1 in human B cell activation: inhibition of B cell proliferation and the generation of immunoglobulin-secreting cells by an antibody against human leukocytic pyrogen. J Immunol. 1983 Jun; 130(6):2708-14.
Score: 0.003
-
Que X, Kim SH, Sajid M, Eckmann L, Dinarello CA, McKerrow JH, Reed SL. A surface amebic cysteine proteinase inactivates interleukin-18. Infect Immun. 2003 Mar; 71(3):1274-80.
Score: 0.002
-
Voronov E, Shouval DS, Krelin Y, Cagnano E, Benharroch D, Iwakura Y, Dinarello CA, Apte RN. IL-1 is required for tumor invasiveness and angiogenesis. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2645-50.
Score: 0.002
-
Banda NK, Vondracek A, Kraus D, Dinarello CA, Kim SH, Bendele A, Senaldi G, Arend WP. Mechanisms of inhibition of collagen-induced arthritis by murine IL-18 binding protein. J Immunol. 2003 Feb 15; 170(4):2100-5.
Score: 0.002
-
Dinarello CA, Marnoy SO, Rosenwasser LJ. Role of arachidonate metabolism in the immunoregulatory function of human leukocytic pyrogen/lymphocyte-activating factor/interleukin 1. J Immunol. 1983 Feb; 130(2):890-5.
Score: 0.002
-
Bufler P, Azam T, Gamboni-Robertson F, Reznikov LL, Kumar S, Dinarello CA, Kim SH. A complex of the IL-1 homologue IL-1F7b and IL-18-binding protein reduces IL-18 activity. Proc Natl Acad Sci U S A. 2002 Oct 15; 99(21):13723-8.
Score: 0.002
-
Raeburn CD, Dinarello CA, Zimmerman MA, Calkins CM, Pomerantz BJ, McIntyre RC, Harken AH, Meng X. Neutralization of IL-18 attenuates lipopolysaccharide-induced myocardial dysfunction. Am J Physiol Heart Circ Physiol. 2002 Aug; 283(2):H650-7.
Score: 0.002
-
Yatsiv I, Morganti-Kossmann MC, Perez D, Dinarello CA, Novick D, Rubinstein M, Otto VI, Rancan M, Kossmann T, Redaelli CA, Trentz O, Shohami E, Stahel PF. Elevated intracranial IL-18 in humans and mice after traumatic brain injury and evidence of neuroprotective effects of IL-18-binding protein after experimental closed head injury. J Cereb Blood Flow Metab. 2002 Aug; 22(8):971-8.
Score: 0.002
-
Dinarello CA, Wolff SM. Production of fever and its effects on the host. Klin Wochenschr. 1982 Jul 15; 60(14):727-30.
Score: 0.002
-
Stuyt RJ, Netea MG, Verschueren I, Fantuzzi G, Dinarello CA, Van Der Meer JW, Kullberg BJ. Role of interleukin-18 in host defense against disseminated Candida albicans infection. Infect Immun. 2002 Jun; 70(6):3284-6.
Score: 0.002
-
Dinarello CA, Wolff SM. Molecular basis of fever in humans. Am J Med. 1982 May; 72(5):799-819.
Score: 0.002
-
Netea MG, Kullberg BJ, Galama JM, Stalenhoef AF, Dinarello CA, Van der Meer JW. Non-LPS components of Chlamydia pneumoniae stimulate cytokine production through Toll-like receptor 2-dependent pathways. Eur J Immunol. 2002 04; 32(4):1188-95.
Score: 0.002
-
Wieland CW, Siegmund B, Senaldi G, Vasil ML, Dinarello CA, Fantuzzi G. Pulmonary inflammation induced by Pseudomonas aeruginosa lipopolysaccharide, phospholipase C, and exotoxin A: role of interferon regulatory factor 1. Infect Immun. 2002 Mar; 70(3):1352-8.
Score: 0.002
-
Im SH, Kim SH, Azam T, Venkatesh N, Dinarello CA, Fuchs S, Souroujon MC. Rat interleukin-18 binding protein: cloning, expression, and characterization. J Interferon Cytokine Res. 2002 Mar; 22(3):321-8.
Score: 0.002
-
Leoni F, Zaliani A, Bertolini G, Porro G, Pagani P, Pozzi P, Donà G, Fossati G, Sozzani S, Azam T, Bufler P, Fantuzzi G, Goncharov I, Kim SH, Pomerantz BJ, Reznikov LL, Siegmund B, Dinarello CA, Mascagni P. The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines. Proc Natl Acad Sci U S A. 2002 Mar 05; 99(5):2995-3000.
Score: 0.002
-
Schultz MJ, Rijneveld AW, Florquin S, Edwards CK, Dinarello CA, van der Poll T. Role of interleukin-1 in the pulmonary immune response during Pseudomonas aeruginosa pneumonia. Am J Physiol Lung Cell Mol Physiol. 2002 Feb; 282(2):L285-90.
Score: 0.002
-
Calkins CM, Bensard DD, Shames BD, Pulido EJ, Abraham E, Fernandez N, Meng X, Dinarello CA, McIntyre RC. IL-1 regulates in vivo C-X-C chemokine induction and neutrophil sequestration following endotoxemia. J Endotoxin Res. 2002; 8(1):59-67.
Score: 0.002
-
Perales MA, Fantuzzi G, Goldberg SM, Turk MJ, Mortazavi F, Busam K, Houghton AN, Dinarello CA, Wolchok JD. GM-CSF DNA induces specific patterns of cytokines and chemokines in the skin: implications for DNA vaccines. Cytokines Cell Mol Ther. 2002; 7(3):125-33.
Score: 0.002
-
Dinarello CA, Rosenwasser LJ, Wolff SM. Demonstration of a circulating suppressor factor of thymocyte proliferation during endotoxin fever in humans. J Immunol. 1981 Dec; 127(6):2517-9.
Score: 0.002
-
Plater-Zyberk C, Joosten LA, Helsen MM, Sattonnet-Roche P, Siegfried C, Alouani S, van De Loo FA, Graber P, Aloni S, Cirillo R, Lubberts E, Dinarello CA, van Den Berg WB, Chvatchko Y. Therapeutic effect of neutralizing endogenous IL-18 activity in the collagen-induced model of arthritis. J Clin Invest. 2001 Dec; 108(12):1825-32.
Score: 0.002
-
Mordue DG, Monroy F, La Regina M, Dinarello CA, Sibley LD. Acute toxoplasmosis leads to lethal overproduction of Th1 cytokines. J Immunol. 2001 Oct 15; 167(8):4574-84.
Score: 0.002
-
Siegmund B, Fantuzzi G, Rieder F, Gamboni-Robertson F, Lehr HA, Hartmann G, Dinarello CA, Endres S, Eigler A. Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-gamma and TNF-alpha production. Am J Physiol Regul Integr Comp Physiol. 2001 Oct; 281(4):R1264-73.
Score: 0.002
-
Rosenwasser LJ, Dinarello CA. Ability of human leukocytic pyrogen to enhance phytohemagglutinin induced murine thymocyte proliferation. Cell Immunol. 1981 Sep 01; 63(1):134-42.
Score: 0.002
-
Dinarello CA, Bernheim HA. Ability of human leukocytic pyrogen to stimulate brain prostaglandin synthesis in vitro. J Neurochem. 1981 Sep; 37(3):702-8.
Score: 0.002
-
Heimbach JK, Reznikov LL, Calkins CM, Robinson TN, Dinarello CA, Harken AH, Meng X. TNF receptor I is required for induction of macrophage heat shock protein 70. Am J Physiol Cell Physiol. 2001 Jul; 281(1):C241-7.
Score: 0.002
-
Novick D, Schwartsburd B, Pinkus R, Suissa D, Belzer I, Sthoeger Z, Keane WF, Chvatchko Y, Kim SH, Fantuzzi G, Dinarello CA, Rubinstein M. A novel IL-18BP ELISA shows elevated serum IL-18BP in sepsis and extensive decrease of free IL-18. Cytokine. 2001 Jun 21; 14(6):334-42.
Score: 0.002
-
Knotek M, Rogachev B, Wang W, Ecder T, Melnikov V, Gengaro PE, Esson M, Edelstein CL, Dinarello CA, Schrier RW. Endotoxemic renal failure in mice: Role of tumor necrosis factor independent of inducible nitric oxide synthase. Kidney Int. 2001 Jun; 59(6):2243-9.
Score: 0.002
-
Melnikov VY, Ecder T, Fantuzzi G, Siegmund B, Lucia MS, Dinarello CA, Schrier RW, Edelstein CL. Impaired IL-18 processing protects caspase-1-deficient mice from ischemic acute renal failure. J Clin Invest. 2001 May; 107(9):1145-52.
Score: 0.002
-
Vázquez-Torres A, Fantuzzi G, Edwards CK, Dinarello CA, Fang FC. Defective localization of the NADPH phagocyte oxidase to Salmonella-containing phagosomes in tumor necrosis factor p55 receptor-deficient macrophages. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2561-5.
Score: 0.002
-
Fantuzzi G, Reed D, Qi M, Scully S, Dinarello CA, Senaldi G. Role of interferon regulatory factor-1 in the regulation of IL-18 production and activity. Eur J Immunol. 2001 Feb; 31(2):369-75.
Score: 0.002
-
Joosten LA, van De Loo FA, Lubberts E, Helsen MM, Netea MG, van Der Meer JW, Dinarello CA, van Den Berg WB. An IFN-gamma-independent proinflammatory role of IL-18 in murine streptococcal cell wall arthritis. J Immunol. 2000 Dec 01; 165(11):6553-8.
Score: 0.002
-
Hong TP, Andersen NA, Nielsen K, Karlsen AE, Fantuzzi G, Eizirik DL, Dinarello CA, Mandrup-Poulsen T. Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma. Eur Cytokine Netw. 2000 Jun; 11(2):193-205.
Score: 0.002
-
Faggioni R, Jones-Carson J, Reed DA, Dinarello CA, Feingold KR, Grunfeld C, Fantuzzi G. Leptin-deficient (ob/ob) mice are protected from T cell-mediated hepatotoxicity: role of tumor necrosis factor alpha and IL-18. Proc Natl Acad Sci U S A. 2000 Feb 29; 97(5):2367-72.
Score: 0.002
-
Wolff SM, Dinarello CA. The Jeremiah Metzger Lecture. The pathogenesis of fever in human subjects. Trans Am Clin Climatol Assoc. 1980; 91:159-66.
Score: 0.002
-
Abraham E, Matthay MA, Dinarello CA, Vincent JL, Cohen J, Opal SM, Glauser M, Parsons P, Fisher CJ, Repine JE. Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome: time for a reevaluation. Crit Care Med. 2000 Jan; 28(1):232-5.
Score: 0.002
-
Sheridan BC, Dinarello CA, Meldrum DR, Fullerton DA, Selzman CH, McIntyre RC. Interleukin-11 attenuates pulmonary inflammation and vasomotor dysfunction in endotoxin-induced lung injury. Am J Physiol. 1999 11; 277(5):L861-7.
Score: 0.002
-
Netea MG, Kullberg BJ, Boerman OC, Verschueren I, Dinarello CA, Van der Meer JW. Soluble murine IL-1 receptor type I induces release of constitutive IL-1 alpha. J Immunol. 1999 Apr 15; 162(8):4876-81.
Score: 0.002
-
Dinarello CA. Production of endogenous pyrogen. Fed Proc. 1979 Jan; 38(1):52-6.
Score: 0.002
-
Faggioni R, Fantuzzi G, Gabay C, Moser A, Dinarello CA, Feingold KR, Grunfeld C. Leptin deficiency enhances sensitivity to endotoxin-induced lethality. Am J Physiol. 1999 01; 276(1):R136-42.
Score: 0.002
-
Novick D, Kim SH, Fantuzzi G, Reznikov LL, Dinarello CA, Rubinstein M. Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response. Immunity. 1999 Jan; 10(1):127-36.
Score: 0.002
-
Dinarello CA, Elin RJ, Chedid L, Wolff SM. The pyrogenicity of the synthetic adjuvant muramyl dipeptide and two structural analogues. J Infect Dis. 1978 Dec; 138(6):760-7.
Score: 0.002
-
Meldrum DR, Dinarello CA, Shames BD, Cleveland JC, Cain BS, Banerjee A, Meng X, Harken AH. Ischemic preconditioning decreases postischemic myocardial tumor necrosis factor-alpha production. Potential ultimate effector mechanism of preconditioning. Circulation. 1998 Nov 10; 98(19 Suppl):II214-8; discussion II218-9.
Score: 0.002
-
Freeman LM, Rush JE, Kehayias JJ, Ross JN, Meydani SN, Brown DJ, Dolnikowski GG, Marmor BN, White ME, Dinarello CA, Roubenoff R. Nutritional alterations and the effect of fish oil supplementation in dogs with heart failure. J Vet Intern Med. 1998 Nov-Dec; 12(6):440-8.
Score: 0.002
-
Meldrum DR, Dinarello CA, Cleveland JC, Cain BS, Shames BD, Meng X, Harken AH. Hydrogen peroxide induces tumor necrosis factor alpha-mediated cardiac injury by a P38 mitogen-activated protein kinase-dependent mechanism. Surgery. 1998 Aug; 124(2):291-6; discussion 297.
Score: 0.002
-
Larsen CM, Wadt KA, Juhl LF, Andersen HU, Karlsen AE, Su MS, Seedorf K, Shapiro L, Dinarello CA, Mandrup-Poulsen T. Interleukin-1beta-induced rat pancreatic islet nitric oxide synthesis requires both the p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases. J Biol Chem. 1998 Jun 12; 273(24):15294-300.
Score: 0.002
-
Rubinstein M, Dinarello CA, Oppenheim JJ, Hertzog P. Recent advances in cytokines, cytokine receptors and signal transduction. Cytokine Growth Factor Rev. 1998 Jun; 9(2):175-81.
Score: 0.002
-
Badovinac V, Mostarica-Stojkovic M, Dinarello CA, Stosic-Grujicic S. Interleukin-1 receptor antagonist suppresses experimental autoimmune encephalomyelitis (EAE) in rats by influencing the activation and proliferation of encephalitogenic cells. J Neuroimmunol. 1998 May 01; 85(1):87-95.
Score: 0.002
-
Cain BS, Meldrum DR, Dinarello CA, Meng X, Banerjee A, Harken AH. Adenosine reduces cardiac TNF-alpha production and human myocardial injury following ischemia-reperfusion. J Surg Res. 1998 May; 76(2):117-23.
Score: 0.002
-
Dinarello CA, Wolff SM. Pathogenesis of fever in man. N Engl J Med. 1978 Mar 16; 298(11):607-12.
Score: 0.002
-
Faggioni R, Fantuzzi G, Fuller J, Dinarello CA, Feingold KR, Grunfeld C. IL-1 beta mediates leptin induction during inflammation. Am J Physiol. 1998 01; 274(1):R204-8.
Score: 0.002
-
Tilg H, Dinarello CA, Mier JW. IL-6 and APPs: anti-inflammatory and immunosuppressive mediators. Immunol Today. 1997 Sep; 18(9):428-32.
Score: 0.002
-
Dinarello CA, Renfer L, Wolff SM. The production of antibody against human leukocytic pyrogen. J Clin Invest. 1977 Aug; 60(2):465-72.
Score: 0.002
-
Le Tulzo Y, Shenkar R, Kaneko D, Moine P, Fantuzzi G, Dinarello CA, Abraham E. Hemorrhage increases cytokine expression in lung mononuclear cells in mice: involvement of catecholamines in nuclear factor-kappaB regulation and cytokine expression. J Clin Invest. 1997 Apr 01; 99(7):1516-24.
Score: 0.002
-
Alheim K, Chai Z, Fantuzzi G, Hasanvan H, Malinowsky D, Di Santo E, Ghezzi P, Dinarello CA, Bartfai T. Hyperresponsive febrile reactions to interleukin (IL) 1alpha and IL-1beta, and altered brain cytokine mRNA and serum cytokine levels, in IL-1beta-deficient mice. Proc Natl Acad Sci U S A. 1997 Mar 18; 94(6):2681-6.
Score: 0.002
-
Roubenoff R, Freeman LM, Smith DE, Abad LW, Dinarello CA, Kehayias JJ. Adjuvant arthritis as a model of inflammatory cachexia. Arthritis Rheum. 1997 Mar; 40(3):534-9.
Score: 0.002
-
Torcia M, Lucibello M, Vannier E, Fabiani S, Miliani A, Guidi G, Spada O, Dower SK, Sims JE, Shaw AR, Dinarello CA, Garaci E, Cozzolino F. Modulation of osteoclast-activating factor activity of multiple myeloma bone marrow cells by different interleukin-1 inhibitors. Exp Hematol. 1996 Jul; 24(8):868-74.
Score: 0.002
-
Benigni F, Fantuzzi G, Sacco S, Sironi M, Pozzi P, Dinarello CA, Sipe JD, Poli V, Cappelletti M, Paonessa G, Pennica D, Panayotatos N, Ghezzi P. Six different cytokines that share GP130 as a receptor subunit, induce serum amyloid A and potentiate the induction of interleukin-6 and the activation of the hypothalamus-pituitary-adrenal axis by interleukin-1. Blood. 1996 Mar 01; 87(5):1851-4.
Score: 0.002
-
McKenzie RC, Oran A, Dinarello CA, Sauder DN. Interleukin-1 receptor antagonist inhibits subcutaneous B16 melanoma growth in vivo. Anticancer Res. 1996 Jan-Feb; 16(1):437-41.
Score: 0.002
-
Kondo S, Pastore S, Fujisawa H, Shivji GM, McKenzie RC, Dinarello CA, Sauder DN. Interleukin-1 receptor antagonist suppresses contact hypersensitivity. J Invest Dermatol. 1995 Sep; 105(3):334-8.
Score: 0.001
-
Granowitz EV, Saget BM, Wang MZ, Dinarello CA, Skolnik PR. Interleukin 1 induces HIV-1 expression in chronically infected U1 cells: blockade by interleukin 1 receptor antagonist and tumor necrosis factor binding protein type 1. Mol Med. 1995 Sep; 1(6):667-77.
Score: 0.001
-
Fantuzzi G, Benigni F, Sironi M, Conni M, Carelli M, Cantoni L, Shapiro L, Dinarello CA, Sipe JD, Ghezzi P. Ciliary neurotrophic factor (CNTF) induces serum amyloid A, hypoglycaemia and anorexia, and potentiates IL-1 induced corticosterone and IL-6 production in mice. Cytokine. 1995 Feb; 7(2):150-6.
Score: 0.001
-
Mancilla-Ramírez J, Dinarello CA, Santos-Preciado JI. [Phosphatidylcholine induces an increase in the production of interleukin-6 and improves survival of rats with neonatal sepsis caused by Klebsiella pneumoniae]. Gac Med Mex. 1995 Jan-Feb; 131(1):14-22.
Score: 0.001
-
Vogels MT, Mensink EJ, Ye K, Boerman OC, Verschueren CM, Dinarello CA, van der Meer JW. Differential gene expression for IL-1 receptor antagonist, IL-1, and TNF receptors and IL-1 and TNF synthesis may explain IL-1-induced resistance to infection. J Immunol. 1994 Dec 15; 153(12):5772-80.
Score: 0.001
-
Dirkes K, Harris BH, Connolly RJ, Schwaitzberg SD, Dinarello CA, Gelfand JA. Platelet activating factor-antagonist improves survival in experimental staphylococcal septicemia. J Pediatr Surg. 1994 Aug; 29(8):1055-7; discussion 1057-8.
Score: 0.001
-
Dinarello CA, Goldin NP, Wolff SM. Demonstration and characterization of two distinct human leukocytic pyrogens. J Exp Med. 1974 Jun 01; 139(6):1369-81.
Score: 0.001
-
Mester M, Carter EA, Tompkins RG, Gelfand JA, Dinarello CA, Burke JF, Clark BD. Thermal injury induces very early production of interleukin-1 alpha in the rat by mechanisms other than endotoxemia. Surgery. 1994 May; 115(5):588-96.
Score: 0.001
-
Manetti R, Barak V, Piccinni MP, Sampognaro S, Parronchi P, Maggi E, Dinarello CA, Romagnani S. Interleukin-1 favours the in vitro development of type 2 T helper (Th2) human T-cell clones. Res Immunol. 1994 Feb; 145(2):93-100.
Score: 0.001
-
Reinisch N, Wolkersdorfer M, Kähler CM, Ye K, Dinarello CA, Wiedermann CJ. Interleukin-1 receptor type I mRNA in mouse brain as affected by peripheral administration of bacterial lipopolysaccharide. Neurosci Lett. 1994 Jan 31; 166(2):165-7.
Score: 0.001
-
Dinarello CA, Ward SB, Wolff SM. Pyrogenic properties of bleomycin (NSC-125066). Cancer Chemother Rep. 1973 Nov-Dec; 57(4):393-8.
Score: 0.001
-
Erroi A, Fantuzzi G, Mengozzi M, Sironi M, Orencole SF, Clark BD, Dinarello CA, Isetta A, Gnocchi P, Giovarelli M, et al. Differential regulation of cytokine production in lipopolysaccharide tolerance in mice. Infect Immun. 1993 Oct; 61(10):4356-9.
Score: 0.001
-
Zumsteg U, Reimers JI, Pociot F, Mørch L, Helqvist S, Brendel M, Alejandro R, Mandrup-Poulsen T, Dinarello CA, Nerup J. Differential interleukin-1 receptor antagonism on pancreatic beta and alpha cells. Studies in rodent and human islets and in normal rats. Diabetologia. 1993 Aug; 36(8):759-66.
Score: 0.001
-
Mester M, Tompkins RG, Gelfand JA, Dinarello CA, Burke JF, Clark BD. Intestinal production of interleukin-1 alpha during endotoxemia in the mouse. J Surg Res. 1993 Jun; 54(6):584-91.
Score: 0.001
-
Mandrup-Poulsen T, Zumsteg U, Reimers J, Pociot F, Mørch L, Helqvist S, Dinarello CA, Nerup J. Involvement of interleukin 1 and interleukin 1 antagonist in pancreatic beta-cell destruction in insulin-dependent diabetes mellitus. Cytokine. 1993 May; 5(3):185-91.
Score: 0.001
-
Romero LI, Schettini G, Lechan RM, Dinarello CA, Reichlin S. Bacterial lipopolysaccharide induction of IL-6 in rat telencephalic cells is mediated in part by IL-1. Neuroendocrinology. 1993 May; 57(5):892-7.
Score: 0.001
-
Kaplan E, Dinarello CA, Wakabayashi G, Burke JF, Connolly RS, Gelfand JA. Interleukin-1 pretreatment protects against endotoxin-induced hypotension in rabbits: association with decreased tumor necrosis factor levels. J Infect Dis. 1993 Jan; 167(1):244-7.
Score: 0.001
-
Feingold KR, Staprans I, Memon RA, Moser AH, Shigenaga JK, Doerrler W, Dinarello CA, Grunfeld C. Endotoxin rapidly induces changes in lipid metabolism that produce hypertriglyceridemia: low doses stimulate hepatic triglyceride production while high doses inhibit clearance. J Lipid Res. 1992 Dec; 33(12):1765-76.
Score: 0.001
-
Numerof RP, Sipe JD, Trehu EG, Dinarello CA, Mier JW. Suppression of IL-2-induced SAA gene expression in mice by the administration of an IL-1 receptor antagonist. Cytokine. 1992 Nov; 4(6):555-60.
Score: 0.001
-
Memon RA, Feingold KR, Moser AH, Doerrler W, Adi S, Dinarello CA, Grunfeld C. Differential effects of interleukin-1 and tumor necrosis factor on ketogenesis. Am J Physiol. 1992 Aug; 263(2 Pt 1):E301-9.
Score: 0.001
-
Fischer E, Van Zee KJ, Marano MA, Rock CS, Kenney JS, Poutsiaka DD, Dinarello CA, Lowry SF, Moldawer LL. Interleukin-1 receptor antagonist circulates in experimental inflammation and in human disease. Blood. 1992 May 01; 79(9):2196-200.
Score: 0.001
-
Feingold KR, Doerrler W, Dinarello CA, Fiers W, Grunfeld C. Stimulation of lipolysis in cultured fat cells by tumor necrosis factor, interleukin-1, and the interferons is blocked by inhibition of prostaglandin synthesis. Endocrinology. 1992 Jan; 130(1):10-6.
Score: 0.001
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Houba V, Berger FM, Dinarello CA, Johnson AG, Le J, Mauël J, Van der Meer JW, Philippeaux MM, Vilcek J, Vogels MT. Protodyne: an immunostimulatory protein component, prepared from gram-positive Bacillus subtilis. Dev Biol Stand. 1992; 77:121-8.
Score: 0.001
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Cohan VL, Scott AL, Dinarello CA, Prendergast RA. Interleukin-1 is a mucus secretagogue. Cell Immunol. 1991 Sep; 136(2):425-34.
Score: 0.001
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Guénard V, Dinarello CA, Weston PJ, Aebischer P. Peripheral nerve regeneration is impeded by interleukin-1 receptor antagonist released from a polymeric guidance channel. J Neurosci Res. 1991 Jul; 29(3):396-400.
Score: 0.001
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Grunfeld C, Soued M, Adi S, Moser AH, Fiers W, Dinarello CA, Feingold KR. Interleukin 4 inhibits stimulation of hepatic lipogenesis by tumor necrosis factor, interleukin 1, and interleukin 6 but not by interferon-alpha. Cancer Res. 1991 Jun 01; 51(11):2803-7.
Score: 0.001
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Feingold KR, Soued M, Adi S, Staprans I, Neese R, Shigenaga J, Doerrler W, Moser A, Dinarello CA, Grunfeld C. Effect of interleukin-1 on lipid metabolism in the rat. Similarities to and differences from tumor necrosis factor. Arterioscler Thromb. 1991 May-Jun; 11(3):495-500.
Score: 0.001
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Clinton SK, Fleet JC, Loppnow H, Salomon RN, Clark BD, Cannon JG, Shaw AR, Dinarello CA, Libby P. Interleukin-1 gene expression in rabbit vascular tissue in vivo. Am J Pathol. 1991 Apr; 138(4):1005-14.
Score: 0.001
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Miller LG, Galpern WR, Dunlap K, Dinarello CA, Turner TJ. Interleukin-1 augments gamma-aminobutyric acidA receptor function in brain. Mol Pharmacol. 1991 Feb; 39(2):105-8.
Score: 0.001
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Grunfeld C, Soued M, Adi S, Moser AH, Dinarello CA, Feingold KR. Evidence for two classes of cytokines that stimulate hepatic lipogenesis: relationships among tumor necrosis factor, interleukin-1 and interferon-alpha. Endocrinology. 1990 Jul; 127(1):46-54.
Score: 0.001
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Kandel RA, Petelycky M, Dinarello CA, Minden M, Pritzker KP, Cruz TF. Comparison of the effect of interleukin 6 and interleukin 1 on collagenase and proteoglycan production by chondrocytes. J Rheumatol. 1990 Jul; 17(7):953-7.
Score: 0.001
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Koenig JI, Snow K, Clark BD, Toni R, Cannon JG, Shaw AR, Dinarello CA, Reichlin S, Lee SL, Lechan RM. Intrinsic pituitary interleukin-1 beta is induced by bacterial lipopolysaccharide. Endocrinology. 1990 Jun; 126(6):3053-8.
Score: 0.001
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Lechan RM, Toni R, Clark BD, Cannon JG, Shaw AR, Dinarello CA, Reichlin S. Immunoreactive interleukin-1 beta localization in the rat forebrain. Brain Res. 1990 Apr 23; 514(1):135-40.
Score: 0.001
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Wilson CS, Ellner JJ, Dinarello CA, Keusch GT, el Kholy A. Dissociation of immunoregulatory function of blood monocytes from maturational state and expression of interleukin-1 in humans chronically infected with Schistosoma mansoni. Am J Trop Med Hyg. 1990 Mar; 42(3):234-42.
Score: 0.001
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Cominelli F, Nast CC, Llerena R, Dinarello CA, Zipser RD. Interleukin 1 suppresses inflammation in rabbit colitis. Mediation by endogenous prostaglandins. J Clin Invest. 1990 Feb; 85(2):582-6.
Score: 0.001
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Wogensen LD, Kolb-Bachofen V, Christensen P, Dinarello CA, Mandrup-Poulsen T, Martin S, Nerup J. Functional and morphological effects of interleukin-1 beta on the perfused rat pancreas. Diabetologia. 1990 Jan; 33(1):15-23.
Score: 0.001
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Cominelli F, Nast CC, Dinarello CA, Gentilini P, Zipser RD. Regulation of eicosanoid production in rabbit colon by interleukin-1. Gastroenterology. 1989 Dec; 97(6):1400-5.
Score: 0.001
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Kwiatkowski D, Cannon JG, Manogue KR, Cerami A, Dinarello CA, Greenwood BM. Tumour necrosis factor production in Falciparum malaria and its association with schizont rupture. Clin Exp Immunol. 1989 Sep; 77(3):361-6.
Score: 0.001
-
Feingold KR, Soued M, Serio MK, Moser AH, Dinarello CA, Grunfeld C. Multiple cytokines stimulate hepatic lipid synthesis in vivo. Endocrinology. 1989 Jul; 125(1):267-74.
Score: 0.001
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Gottlieb RA, Lennarz WJ, Knowles RD, Cianciolo GJ, Dinarello CA, Lachman LB, Kleinerman ES. Synthetic peptide corresponding to a conserved domain of the retroviral protein p15E blocks IL-1-mediated signal transduction. J Immunol. 1989 Jun 15; 142(12):4321-8.
Score: 0.001
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Flores EA, Bistrian BR, Pomposelli JJ, Dinarello CA, Blackburn GL, Istfan NW. Infusion of tumor necrosis factor/cachectin promotes muscle catabolism in the rat. A synergistic effect with interleukin 1. J Clin Invest. 1989 May; 83(5):1614-22.
Score: 0.001
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Cannon JG, Clark BD, Wingfield P, Schmeissner U, Losberger C, Dinarello CA, Shaw AR. Rabbit IL-1. Cloning, expression, biologic properties, and transcription during endotoxemia. J Immunol. 1989 Apr 01; 142(7):2299-306.
Score: 0.001
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Prakash S, Dinarello CA, Danko K, Stadecker MJ, Wyler DJ. Schistosomal egg granuloma-derived fibroblast-stimulating factor is apparently distinct from interleukin-1. Infect Immun. 1989 Mar; 57(3):679-84.
Score: 0.001
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Flores EA, Drabik M, Gauldie J, Blackburn GL, Dinarello CA, Bistrian BR. Leukocyte endogenous mediator fails to alter protein dynamics in a model of liver dysfunction. J Lab Clin Med. 1989 Feb; 113(2):211-20.
Score: 0.001
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White CW, Ghezzi P, McMahon S, Dinarello CA, Repine JE. Cytokines increase rat lung antioxidant enzymes during exposure to hyperoxia. J Appl Physiol (1985). 1989 Feb; 66(2):1003-7.
Score: 0.001
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Scarborough DE, Lee SL, Dinarello CA, Reichlin S. Interleukin-1 beta stimulates somatostatin biosynthesis in primary cultures of fetal rat brain. Endocrinology. 1989 Jan; 124(1):549-51.
Score: 0.001
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Cady AB, Riveau G, Chedid L, Dinarello CA, Johannsen L, Krueger JM. Interleukin-1-induced sleep and febrile responses differentially altered by a muramyl dipeptide derivative. Int J Immunopharmacol. 1989; 11(8):887-93.
Score: 0.001
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Kaplan E, Dinarello CA, Gelfand JA. Interleukin-1 and the response to injury. Immunol Res. 1989; 8(2):118-29.
Score: 0.001
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Tredget EE, Yu YM, Zhong S, Burini R, Okusawa S, Gelfand JA, Dinarello CA, Young VR, Burke JF. Role of interleukin 1 and tumor necrosis factor on energy metabolism in rabbits. Am J Physiol. 1988 Dec; 255(6 Pt 1):E760-8.
Score: 0.001
-
Beasley D, Dinarello CA, Cannon JG. Interleukin-1 induces natriuresis in conscious rats: role of renal prostaglandins. Kidney Int. 1988 Jun; 33(6):1059-65.
Score: 0.001
-
Shaldon S, Dinarello C, Port F, Kluger M. Interleukin-1: the pros and cons of its clinical relevance. Artif Organs. 1988 Jun; 12(3):221.
Score: 0.001
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Domer FR, Mori K, Dinarello CA, Sokoloff L. Effects of leukocytic pyrogen (interleukin-1) on local cerebral glucose utilization in rats with and without premedication with indomethacin or dexamethasone. J Cereb Blood Flow Metab. 1988 Apr; 8(2):173-8.
Score: 0.001
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Ranges GE, Zlotnik A, Espevik T, Dinarello CA, Cerami A, Palladino MA. Tumor necrosis factor alpha/cachectin is a growth factor for thymocytes. Synergistic interactions with other cytokines. J Exp Med. 1988 Apr 01; 167(4):1472-8.
Score: 0.001
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Wogensen LD, Mandrup-Poulsen T, Markholst H, Mølvig J, Lernmark A, Holst JJ, Dinarello CA, Nerup J. Interleukin-1 potentiates glucose stimulated insulin release in the isolated perfused pancreas. Acta Endocrinol (Copenh). 1988 Mar; 117(3):302-6.
Score: 0.001
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Zsebo KM, Yuschenkoff VN, Schiffer S, Chang D, McCall E, Dinarello CA, Brown MA, Altrock B, Bagby GC. Vascular endothelial cells and granulopoiesis: interleukin-1 stimulates release of G-CSF and GM-CSF. Blood. 1988 Jan; 71(1):99-103.
Score: 0.001
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Ruwe WD, Naylor AM, Dinarello CA, Veale WL. Characteristics of pyrogen fevers are altered in the aged rabbit. Exp Gerontol. 1988; 23(2):103-13.
Score: 0.001
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Dinarello CA, Bodel PT, Atkins E. The role of the liver in the production of fever and in pyrogenic tolerance. Trans Assoc Am Physicians. 1968; 81:334-44.
Score: 0.001
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Mandrup-Poulsen T, Bendtzen K, Dinarello CA, Nerup J. Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity. J Immunol. 1987 Dec 15; 139(12):4077-82.
Score: 0.001
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Tocco-Bradley R, Georgieff M, Jones CT, Moldawer LL, Dinarello CA, Blackburn GL, Bistrian BR. Changes in energy expenditure and fat metabolism in rats infused with interleukin-1. Eur J Clin Invest. 1987 Dec; 17(6):504-10.
Score: 0.001
-
Woo P, Sipe J, Dinarello CA, Colten HR. Structure of a human serum amyloid A gene and modulation of its expression in transfected L cells. J Biol Chem. 1987 Nov 15; 262(32):15790-5.
Score: 0.001
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Kandel RA, Dinarello CA, Biswas C. The stimulation of collagenase production in rabbit articular chondrocytes by interleukin-1 is increased by collagens. Biochem Int. 1987 Nov; 15(5):1021-31.
Score: 0.001
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Bishai I, Dinarello CA, Coceani F. Prostaglandin formation in feline cerebral microvessels: effect of endotoxin and interleukin-1. Can J Physiol Pharmacol. 1987 Nov; 65(11):2225-30.
Score: 0.001
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Mier JW, Dinarello CA, Atkins MB, Punsal PI, Perlmutter DH. Regulation of hepatic acute phase protein synthesis by products of interleukin 2 (IL 2)-stimulated human peripheral blood mononuclear cells. J Immunol. 1987 Aug 15; 139(4):1268-72.
Score: 0.001
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Roh MS, Drazenovich KA, Barbose JJ, Dinarello CA, Cobb CF. Direct stimulation of the adrenal cortex by interleukin-1. Surgery. 1987 Aug; 102(2):140-6.
Score: 0.001
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Spinas GA, Hansen BS, Linde S, Kastern W, Mølvig J, Mandrup-Poulsen T, Dinarello CA, Nielsen JH, Nerup J. Interleukin 1 dose-dependently affects the biosynthesis of (pro)insulin in isolated rat islets of Langerhans. Diabetologia. 1987 Jul; 30(7):474-80.
Score: 0.001
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Shoham S, Davenne D, Cady AB, Dinarello CA, Krueger JM. Recombinant tumor necrosis factor and interleukin 1 enhance slow-wave sleep. Am J Physiol. 1987 Jul; 253(1 Pt 2):R142-9.
Score: 0.001
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Mannie MD, Dinarello CA, Paterson PY. Interleukin 1 and myelin basic protein synergistically augment adoptive transfer activity of lymphocytes mediating experimental autoimmune encephalomyelitis in Lewis rats. J Immunol. 1987 Jun 15; 138(12):4229-35.
Score: 0.001
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Rustgi VK, Jones DB, Dinarello CA, Hoofnagle JH. Lymphokines and bile secretion in the rat. Liver. 1987 Jun; 7(3):149-54.
Score: 0.001
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White CW, Ghezzi P, Dinarello CA, Caldwell SA, McMurtry IF, Repine JE. Recombinant tumor necrosis factor/cachectin and interleukin 1 pretreatment decreases lung oxidized glutathione accumulation, lung injury, and mortality in rats exposed to hyperoxia. J Clin Invest. 1987 Jun; 79(6):1868-73.
Score: 0.001
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Riveau GR, Novitsky TJ, Roslansky PF, Dinarello CA, Warren HS. Role of interleukin-1 in augmenting serum neutralization of bacterial lipopolysaccharide. J Clin Microbiol. 1987 May; 25(5):889-92.
Score: 0.001
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Le PT, Tuck DT, Dinarello CA, Haynes BF, Singer KH. Human thymic epithelial cells produce interleukin 1. J Immunol. 1987 Apr 15; 138(8):2520-6.
Score: 0.001
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Drabik MD, Schnure FC, Mok KT, Moldawer LL, Dinarello CA, Blackburn GL, Bistrian BR. Effect of protein depletion and short-term parenteral refeeding on the host response to interleukin 1 administration. J Lab Clin Med. 1987 Apr; 109(4):509-16.
Score: 0.001
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Naylor AM, Gubitz GJ, Dinarello CA, Veale WL. Central effects of vasopressin and 1-desamino-8-D-arginine vasopressin (DDAVP) on interleukin-1 fever in the rat. Brain Res. 1987 Jan 13; 401(1):173-7.
Score: 0.001
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Yodoi J, Okada M, Tagaya Y, Taniguchi Y, Teshigawara K, Kasahara T, Dinarello CA, Matsushima K, Honko T, Uchiyama T, et al. IL-2 receptor gene activation by ATL-derived factor (ADF). Adv Exp Med Biol. 1987; 213:139-48.
Score: 0.001
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Krueger JM, Dinarello CA, Shoham S, Davenne D, Walter J, Kubillus S. Interferon alpha-2 enhances slow-wave sleep in rabbits. Int J Immunopharmacol. 1987; 9(1):23-30.
Score: 0.001
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Spinas GA, Mandrup-Poulsen T, Mølvig J, Baek L, Bendtzen K, Dinarello CA, Nerup J. Low concentrations of interleukin-1 stimulate and high concentrations inhibit insulin release from isolated rat islets of Langerhans. Acta Endocrinol (Copenh). 1986 Dec; 113(4):551-8.
Score: 0.001
-
Perlmutter DH, Dinarello CA, Punsal PI, Colten HR. Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression. J Clin Invest. 1986 Nov; 78(5):1349-54.
Score: 0.001
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Bagby GC, Dinarello CA, Wallace P, Wagner C, Hefeneider S, McCall E. Interleukin 1 stimulates granulocyte macrophage colony-stimulating activity release by vascular endothelial cells. J Clin Invest. 1986 Nov; 78(5):1316-23.
Score: 0.001
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Dustin ML, Rothlein R, Bhan AK, Dinarello CA, Springer TA. Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J Immunol. 1986 Jul 01; 137(1):245-54.
Score: 0.001
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Rosenwasser LJ, Webb AC, Clark BD, Irie S, Chang L, Dinarello CA, Gehrke L, Wolff SM, Rich A, Auron PE. Expression of biologically active human interleukin 1 subpeptides by transfected simian COS cells. Proc Natl Acad Sci U S A. 1986 Jul; 83(14):5243-6.
Score: 0.001
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Bendtzen K, Mandrup-Poulsen T, Nerup J, Nielsen JH, Dinarello CA, Svenson M. Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans. Science. 1986 Jun 20; 232(4757):1545-7.
Score: 0.001
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Perlmutter DH, Goldberger G, Dinarello CA, Mizel SB, Colten HR. Regulation of class III major histocompatibility complex gene products by interleukin-1. Science. 1986 May 16; 232(4752):850-2.
Score: 0.001
-
Knudsen PJ, Dinarello CA, Strom TB. Purification and characterization of a unique human interleukin 1 from the tumor cell line U937. J Immunol. 1986 May 01; 136(9):3311-6.
Score: 0.001
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Roh MS, Moldawer LL, Ekman LG, Dinarello CA, Bistrian BR, Jeevanandam M, Brennan MF. Stimulatory effect of interleukin-1 upon hepatic metabolism. Metabolism. 1986 May; 35(5):419-24.
Score: 0.001
-
Hamawy KJ, Yamazaki K, Georgieff M, Dinarello CA, Moldawer LL, Blackburn GL, Bistrian BR. Improvements in host immunity by partially purified interleukin 1 in rats with portacaval anastomosis and splenectomy. JPEN J Parenter Enteral Nutr. 1986 Mar-Apr; 10(2):146-50.
Score: 0.001
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Valentine M, Lotz M, Dinarello CA, Carson DA, Vaughan JH. Lymphoblastoid B cell lines produce an interleukin-1-like activity that can be serologically distinct from macrophage interleukin-1. Lymphokine Res. 1986; 5(3):173-83.
Score: 0.001
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Walter J, Davenne D, Shoham S, Dinarello CA, Krueger JM. Brain temperature changes coupled to sleep states persist during interleukin 1-enhanced sleep. Am J Physiol. 1986 Jan; 250(1 Pt 2):R96-103.
Score: 0.001
-
Hamby BA, Huggins EM, Lachman LB, Dinarello CA, Sigel MM. Fish lymphocytes respond to human IL-1. Lymphokine Res. 1986; 5(2):157-62.
Score: 0.001
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Mandrup-Poulsen T, Bendtzen K, Nerup J, Dinarello CA, Svenson M, Nielsen JH. Affinity-purified human interleukin I is cytotoxic to isolated islets of Langerhans. Diabetologia. 1986 Jan; 29(1):63-7.
Score: 0.001
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Ahmed MS, Llanos-Q J, Dinarello CA, Blatteis CM. Interleukin 1 reduces opioid binding in guinea pig brain. Peptides. 1985 Nov-Dec; 6(6):1149-54.
Score: 0.001
-
Stern DM, Bank I, Nawroth PP, Cassimeris J, Kisiel W, Fenton JW, Dinarello C, Chess L, Jaffe EA. Self-regulation of procoagulant events on the endothelial cell surface. J Exp Med. 1985 Oct 01; 162(4):1223-35.
Score: 0.001
-
Ramadori G, Sipe JD, Dinarello CA, Mizel SB, Colten HR. Pretranslational modulation of acute phase hepatic protein synthesis by murine recombinant interleukin 1 (IL-1) and purified human IL-1. J Exp Med. 1985 Sep 01; 162(3):930-42.
Score: 0.001
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Chu ET, Lareau M, Rosenwasser LJ, Dinarello CA, Geha RS. Antigen presentation by EBV-B cells to resting and activated T cells: role of interleukin 1. J Immunol. 1985 Mar; 134(3):1676-81.
Score: 0.001
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Williams JM, Dinarello CA, Rosenwasser LJ, Kelley V, Reddish M, Strom TB. Phorbol myristate acetate-protein complex mimics bioactivity of human IL-1. 1. Direct evidence that PMA temporarily enters and is released from cellular compartment during superinduction protocol. Lymphokine Res. 1985; 4(4):275-97.
Score: 0.001
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Auron PE, Rosenwasser LJ, Matsushima K, Copeland T, Dinarello CA, Oppenheim JJ, Webb AC. Human and murine interleukin 1 possess sequence and structural similarities. J Mol Cell Immunol. 1985; 2(3):169-77.
Score: 0.001
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Kaye J, Gillis S, Mizel SB, Shevach EM, Malek TR, Dinarello CA, Lachman LB, Janeway CA. Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2. J Immunol. 1984 Sep; 133(3):1339-45.
Score: 0.001
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Loda M, Clowes GH, Dinarello CA, George BC, Lane B, Richardson W. Induction of hepatic protein synthesis by a peptide in blood plasma of patients with sepsis and trauma. Surgery. 1984 Aug; 96(2):204-13.
Score: 0.001
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Wyler DJ, Stadecker MJ, Dinarello CA, O'Dea JF. Fibroblast stimulation in schistosomiasis. V. Egg granuloma macrophages spontaneously secrete a fibroblast-stimulating factor. J Immunol. 1984 Jun; 132(6):3142-8.
Score: 0.001
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Krueger JM, Walter J, Dinarello CA, Wolff SM, Chedid L. Sleep-promoting effects of endogenous pyrogen (interleukin-1). Am J Physiol. 1984 Jun; 246(6 Pt 2):R994-9.
Score: 0.001
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Ikejima T, Dinarello CA, Gill DM, Wolff SM. Induction of human interleukin-1 by a product of Staphylococcus aureus associated with toxic shock syndrome. J Clin Invest. 1984 May; 73(5):1312-20.
Score: 0.001
-
Chu E, Rosenwasser LJ, Dinarello CA, Lareau M, Geha RS. Role of interleukin 1 in antigen-specific T cell proliferation. J Immunol. 1984 Mar; 132(3):1311-6.
Score: 0.001
-
Sauder DN, Mounessa NL, Katz SI, Dinarello CA, Gallin JI. Chemotactic cytokines: the role of leukocytic pyrogen and epidermal cell thymocyte-activating factor in neutrophil chemotaxis. J Immunol. 1984 Feb; 132(2):828-32.
Score: 0.001
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Sobrado J, Moldawer LL, Bistrian BR, Dinarello CA, Blackburn GL. Effect of ibuprofen on fever and metabolic changes induced by continuous infusion of leukocytic pyrogen (interleukin 1) or endotoxin. Infect Immun. 1983 Dec; 42(3):997-1005.
Score: 0.001
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Coceani F, Bishai I, Dinarello CA, Fitzpatrick FA. Prostaglandin E2 and thromboxane B2 in cerebrospinal fluid of afebrile and febrile cat. Am J Physiol. 1983 Jun; 244(6):R785-93.
Score: 0.001
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Baracos V, Rodemann HP, Dinarello CA, Goldberg AL. Stimulation of muscle protein degradation and prostaglandin E2 release by leukocytic pyrogen (interleukin-1). A mechanism for the increased degradation of muscle proteins during fever. N Engl J Med. 1983 Mar 10; 308(10):553-8.
Score: 0.001
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Chedid L, Bahr GM, Modabber FZ, Dinarello CA, Wolff SM. [Demonstration of a bacterial structure in two human mediators: a sleep facilitating factor and a monokine]. C R Seances Acad Sci III. 1983; 297(4):209-12.
Score: 0.001
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Beer DJ, Dinarello CA, Rosenwasser LJ, Rocklin RE. Human monocyte-derived soluble product(s) has an accessory function in the generation of histamine- and concanavalin A-induced suppressor T cells. J Clin Invest. 1982 Aug; 70(2):393-400.
Score: 0.001
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McAdam KP, Li J, Knowles J, Foss NT, Dinarello CA, Rosenwasser LJ, Selinger MJ, Kaplan MM, Goodman R, Herbert PN, Bausserman LL, Nadler LM. The biology of SAA: identification of the inducer, in vitro synthesis, and heterogeneity demonstrated with monoclonal antibodies. Ann N Y Acad Sci. 1982; 389:126-36.
Score: 0.001
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Hooper DC, Steer CJ, Dinarello CA, Peacock AC. Haptoglobin and albumin synthesis in isolated rat hepatocytes. Response to potential mediators of the acute-phase reaction. Biochim Biophys Acta. 1981 Mar 26; 653(1):118-29.
Score: 0.001
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Parant M, Riveau G, Parant F, Dinarello CA, Wolff SM, Chedid L. Effect of indomethacin on increased resistance to bacterial infection and on febrile responses induced by muramyl dipeptide. J Infect Dis. 1980 Nov; 142(5):708-15.
Score: 0.001
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Rosenwasser LJ, Dinarello CA, Rosenthal AS. Adherent cell function in murine T-lymphocyte antigen recognition. IV. Enhancement of murine T-cell antigen recognition by human leukocytic pyrogen. J Exp Med. 1979 Sep 19; 150(3):709-14.
Score: 0.000
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Lipton JM, Dinarello CA, Kennedy JI. Fever produced in the squirrel monkey by human leukocytic pyrogen. Proc Soc Exp Biol Med. 1979 Apr; 160(4):426-8.
Score: 0.000
-
Perlow M, Dinarello CA, Wolff SM. A primate model for the study of human fever. J Infect Dis. 1975 Aug; 132(2):157-64.
Score: 0.000
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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