 Connection
Charles Dinarello to Interleukin-1
This is a "connection" page, showing publications Charles Dinarello has written about Interleukin-1.
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36.500 |
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de Graaf DM, Wang RX, Amo-Aparicio J, Lee JS, Dowdell AS, Tengesdal IW, Marchetti C, Colgan SP, Joosten LAB, Dinarello CA. IL-38 Gene Deletion Worsens Murine Colitis. Front Immunol. 2022; 13:840719.
Score: 0.552
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Cavalli G, Tengesdal IW, Gresnigt M, Nemkov T, Arts RJW, Domínguez-Andrés J, Molteni R, Stefanoni D, Cantoni E, Cassina L, Giugliano S, Schraa K, Mills TS, Pietras EM, Eisenmensser EZ, Dagna L, Boletta A, D'Alessandro A, Joosten LAB, Netea MG, Dinarello CA. The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity. Cell Rep. 2021 04 06; 35(1):108955.
Score: 0.510
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Abbate A, Toldo S, Marchetti C, Kron J, Van Tassell BW, Dinarello CA. Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease. Circ Res. 2020 04 24; 126(9):1260-1280.
Score: 0.477
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Powers NE, Swartzwelter B, Marchetti C, de Graaf DM, Lerchner A, Schlapschy M, Datar R, Binder U, Edwards CK, Skerra A, Dinarello CA. PASylation of IL-1 receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis. J Biol Chem. 2020 01 17; 295(3):868-882.
Score: 0.465
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Dinarello CA. The IL-1 family of cytokines and receptors in rheumatic diseases. Nat Rev Rheumatol. 2019 10; 15(10):612-632.
Score: 0.457
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Eisenmesser EZ, Gottschlich A, Redzic JS, Paukovich N, Nix JC, Azam T, Zhang L, Zhao R, Kieft JS, The E, Meng X, Dinarello CA. Interleukin-37 monomer is the active form for reducing innate immunity. Proc Natl Acad Sci U S A. 2019 03 19; 116(12):5514-5522.
Score: 0.441
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Li S, Amo-Aparicio J, Neff CP, Tengesdal IW, Azam T, Palmer BE, López-Vales R, Bufler P, Dinarello CA. Role for nuclear interleukin-37 in the suppression of innate immunity. Proc Natl Acad Sci U S A. 2019 03 05; 116(10):4456-4461.
Score: 0.440
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Ballak DB, Li S, Cavalli G, Stahl JL, Tengesdal IW, van Diepen JA, Klück V, Swartzwelter B, Azam T, Tack CJ, Stienstra R, Mandrup-Poulsen T, Seals DR, Dinarello CA. Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue. J Biol Chem. 2018 09 14; 293(37):14224-14236.
Score: 0.422
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Cavalli G, Dinarello CA. Suppression of inflammation and acquired immunity by IL-37. Immunol Rev. 2018 01; 281(1):179-190.
Score: 0.407
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Dinarello CA. Overview of the IL-1 family in innate inflammation and acquired immunity. Immunol Rev. 2018 01; 281(1):8-27.
Score: 0.407
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Dinarello CA. Introduction to the interleukin-1 family of cytokines and receptors: Drivers of innate inflammation and acquired immunity. Immunol Rev. 2018 01; 281(1):5-7.
Score: 0.407
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Cavalli G, Justice JN, Boyle KE, D'Alessandro A, Eisenmesser EZ, Herrera JJ, Hansen KC, Nemkov T, Stienstra R, Garlanda C, Mantovani A, Seals DR, Dagna L, Joosten LA, Ballak DB, Dinarello CA. Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance. Proc Natl Acad Sci U S A. 2017 02 28; 114(9):2313-2318.
Score: 0.383
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Cavalli G, Koenders M, Kalabokis V, Kim J, Tan AC, Garlanda C, Mantovani A, Dagna L, Joosten LA, Dinarello CA. Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation. Rheumatology (Oxford). 2016 Dec; 55(12):2220-2229.
Score: 0.370
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Dinarello CA, Nold-Petry C, Nold M, Fujita M, Li S, Kim S, Bufler P. Suppression of innate inflammation and immunity by interleukin-37. Eur J Immunol. 2016 05; 46(5):1067-81.
Score: 0.362
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Cavalli G, Dinarello CA. Treating rheumatological diseases and co-morbidities with interleukin-1 blocking therapies. Rheumatology (Oxford). 2015 Dec; 54(12):2134-44.
Score: 0.343
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Li S, Neff CP, Barber K, Hong J, Luo Y, Azam T, Palmer BE, Fujita M, Garlanda C, Mantovani A, Kim S, Dinarello CA. Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8. Proc Natl Acad Sci U S A. 2015 Feb 24; 112(8):2497-502.
Score: 0.332
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Dinarello CA. An expanding role for interleukin-1 blockade from gout to cancer. Mol Med. 2014 Dec 16; 20 Suppl 1:S43-58.
Score: 0.329
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Abbate A, Canada JM, Van Tassell BW, Wise CM, Dinarello CA. Interleukin-1 blockade in rheumatoid arthritis and heart failure: a missed opportunity? Int J Cardiol. 2014 Feb 15; 171(3):e125-6.
Score: 0.308
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Dinarello CA, Bufler P. Interleukin-37. Semin Immunol. 2013 Dec 15; 25(6):466-8.
Score: 0.306
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Dinarello CA. Keep up the heat on IL-1. Blood. 2012 Sep 27; 120(13):2538-9.
Score: 0.282
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Dinarello CA, Simon A, van der Meer JW. Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases. Nat Rev Drug Discov. 2012 Aug; 11(8):633-52.
Score: 0.279
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Boraschi D, Lucchesi D, Hainzl S, Leitner M, Maier E, Mangelberger D, Oostingh GJ, Pfaller T, Pixner C, Posselt G, Italiani P, Nold MF, Nold-Petry CA, Bufler P, Dinarello CA. IL-37: a new anti-inflammatory cytokine of the IL-1 family. Eur Cytokine Netw. 2011 Sep; 22(3):127-47.
Score: 0.262
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Dinarello CA. Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. Blood. 2011 Apr 07; 117(14):3720-32.
Score: 0.252
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Dinarello C, Arend W, Sims J, Smith D, Blumberg H, O'Neill L, Goldbach-Mansky R, Pizarro T, Hoffman H, Bufler P, Nold M, Ghezzi P, Mantovani A, Garlanda C, Boraschi D, Rubartelli A, Netea M, van der Meer J, Joosten L, Mandrup-Poulsen T, Donath M, Lewis E, Pfeilschifter J, Martin M, Kracht M, Muehl H, Novick D, Lukic M, Conti B, Solinger A, Kelk P, Peyman K, van de Veerdonk F, Gabel C. IL-1 family nomenclature. Nat Immunol. 2010 Nov; 11(11):973.
Score: 0.247
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Nold MF, Nold-Petry CA, Zepp JA, Palmer BE, Bufler P, Dinarello CA. IL-37 is a fundamental inhibitor of innate immunity. Nat Immunol. 2010 Nov; 11(11):1014-22.
Score: 0.246
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Dinarello CA. Why not treat human cancer with interleukin-1 blockade? Cancer Metastasis Rev. 2010 Jun; 29(2):317-29.
Score: 0.240
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Dinarello CA. IL-1: discoveries, controversies and future directions. Eur J Immunol. 2010 Mar; 40(3):599-606.
Score: 0.236
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Dinarello CA. Interleukin-1beta and the autoinflammatory diseases. N Engl J Med. 2009 Jun 04; 360(23):2467-70.
Score: 0.224
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Dinarello CA. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol. 2009; 27:519-50.
Score: 0.218
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Auron PE, Webb AC, Rosenwasser LJ, Mucci SF, Rich A, Wolff SM, Dinarello CA. Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. Proc. Natl. Acad. Sci. USA 1984. 81: 7907-7911. J Immunol. 2007 May 01; 178(9):5413-7.
Score: 0.194
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Dinarello CA. The paradox of pro-inflammatory cytokines in cancer. Cancer Metastasis Rev. 2006 Sep; 25(3):307-13.
Score: 0.185
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Dinarello CA. Interleukin 1 and interleukin 18 as mediators of inflammation and the aging process. Am J Clin Nutr. 2006 Feb; 83(2):447S-455S.
Score: 0.178
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Dinarello CA. Interleukin-1beta. Crit Care Med. 2005 Dec; 33(12 Suppl):S460-2.
Score: 0.176
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Gonçalves SM, Leite L, de Vasconcelos P, Pereira I, Dewi IMW, Mercier T, Aerts R, Ligeiro D, Mendes F, Freitas F, Condeço J, Vieira J, Espada E, Lagrou K, Maertens JA, Gresnigt MS, Dinarello CA, Lacerda JF, Pinho Vaz C, Cunha C, Carvalho A, van de Veerdonk FL. A Functional Polymorphism in IL-36ß Modulates Macrophage Antifungal Effector Functions and Increases Susceptibility to Invasive Pulmonary Aspergillosis. J Infect Dis. 2025 Nov 14; 232(5):1208-1219.
Score: 0.175
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Schwärzler J, Menghini P, Dinarello C, Cominelli F, Tilg H. IL-1 family of cytokines in gastrointestinal and liver disorders. Nat Rev Gastroenterol Hepatol. 2026 Jan; 23(1):29-43.
Score: 0.175
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Dinarello CA. An IL-1 family member requires caspase-1 processing and signals through the ST2 receptor. Immunity. 2005 Nov; 23(5):461-2.
Score: 0.175
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Dinarello CA. Blocking IL-1 in systemic inflammation. J Exp Med. 2005 May 02; 201(9):1355-9.
Score: 0.169
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Dinarello CA. Therapeutic strategies to reduce IL-1 activity in treating local and systemic inflammation. Curr Opin Pharmacol. 2004 Aug; 4(4):378-85.
Score: 0.160
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Bufler P, Gamboni-Robertson F, Azam T, Kim SH, Dinarello CA. Interleukin-1 homologues IL-1F7b and IL-18 contain functional mRNA instability elements within the coding region responsive to lipopolysaccharide. Biochem J. 2004 Jul 15; 381(Pt 2):503-10.
Score: 0.160
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Lee JK, Kim SH, Lewis EC, Azam T, Reznikov LL, Dinarello CA. Differences in signaling pathways by IL-1beta and IL-18. Proc Natl Acad Sci U S A. 2004 Jun 08; 101(23):8815-20.
Score: 0.158
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Reznikov LL, Waksman J, Azam T, Kim SH, Bufler P, Niwa T, Werman A, Zhang X, Pischetsrieder M, Shaldon S, Dinarello CA. Effect of advanced glycation end products on endotoxin-induced TNF-alpha, IL-1beta and IL-8 in human peripheral blood mononuclear cells. Clin Nephrol. 2004 May; 61(5):324-36.
Score: 0.158
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Gaballa JM, Højen JF, De Graaf DM, Amo-Aparicio J, Marchetti C, Cavalli G, Dinarello A, Li S, Corbisiero MF, Tengesdal IW, Redzic JS, Azam T, Webber WS, Pankratz KA, May MJ, Cominelli F, Eisenmesser EZ, Kim S, Dinarello CA, Boraschi D. International nomenclature guidelines for the IL-1 family of cytokines and receptors. Nat Immunol. 2024 Apr; 25(4):581-582.
Score: 0.157
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Dinarello CA. Unraveling the NALP-3/IL-1beta inflammasome: a big lesson from a small mutation. Immunity. 2004 Mar; 20(3):243-4.
Score: 0.156
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Dinarello A, May M, Amo-Aparicio J, Azam T, Gaballa JM, Marchetti C, Tesoriere A, Ghirardo R, Redzic JS, Webber WS, Atif SM, Li S, Eisenmesser EZ, de Graaf DM, Dinarello CA. IL-38 regulates intestinal stem cell homeostasis by inducing WNT signaling and beneficial IL-1ß secretion. Proc Natl Acad Sci U S A. 2023 11 07; 120(45):e2306476120.
Score: 0.152
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The E, Zhai Y, Yao Q, Ao L, Li S, Fullerton DA, Dinarello CA, Meng X. Recombinant IL-37 Exerts an Anti-inflammatory Effect on Human Aortic Valve Interstitial Cells through Extracellular and Intracellular Actions. Int J Biol Sci. 2023; 19(12):3908-3919.
Score: 0.150
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Dinarello CA. Setting the cytokine trap for autoimmunity. Nat Med. 2003 Jan; 9(1):20-2.
Score: 0.144
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Dinarello CA. The IL-1 family and inflammatory diseases. Clin Exp Rheumatol. 2002 Sep-Oct; 20(5 Suppl 27):S1-13.
Score: 0.140
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Lonnemann N, Hosseini S, Ohm M, Geffers R, Hiller K, Dinarello CA, Korte M. IL-37 expression reduces acute and chronic neuroinflammation and rescues cognitive impairment in an Alzheimer's disease mouse model. Elife. 2022 08 30; 11.
Score: 0.140
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Teufel LU, de Graaf DM, Netea MG, Dinarello CA, Joosten LAB, Arts RJW. Circulating interleukin-38 concentrations in healthy adults. Front Immunol. 2022; 13:964365.
Score: 0.140
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Dinarello CA. Anti-cytokine therapies in response to systemic infection. J Investig Dermatol Symp Proc. 2001 Dec; 6(3):244-50.
Score: 0.133
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van Deuren RC, Arts P, Cavalli G, Jaeger M, Steehouwer M, van de Vorst M, Gilissen C, Joosten LAB, Dinarello CA, Mhlanga MM, Kumar V, Netea MG, van de Veerdonk FL, Hoischen A. Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses. Genome Med. 2021 05 25; 13(1):94.
Score: 0.129
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Kouwenberg M, Pulskens WPC, Diepeveen L, Bakker-van Bebber M, Dinarello CA, Netea MG, Hilbrands LB, van der Vlag J. Reduced CXCL1 production by endogenous IL-37 expressing dendritic cells does not affect T cell activation. PLoS One. 2021; 16(5):e0251809.
Score: 0.129
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Dinarello CA, Muegge K, Durum SK. Measurement of soluble and membrane-bound interleukin 1 using a fibroblast bioassay. Curr Protoc Immunol. 2001 May; Chapter 6:Unit 6.2.
Score: 0.128
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Mountford S, Effenberger M, Noll-Puchta H, Griessmair L, Ringleb A, Haas S, Denk G, Reiter FP, Mayr D, Dinarello CA, Tilg H, Bufler P. Modulation of Liver Inflammation and Fibrosis by Interleukin-37. Front Immunol. 2021; 12:603649.
Score: 0.127
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Pomerantz BJ, Reznikov LL, Harken AH, Dinarello CA. Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2871-6.
Score: 0.127
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Hamilton JAG, Lee MY, Hunter R, Ank RS, Story JY, Talekar G, Sisroe T, Ballak DB, Fedanov A, Porter CC, Eisenmesser EZ, Dinarello CA, Raikar SS, DeGregori J, Henry CJ. Interleukin-37 improves T-cell-mediated immunity and chimeric antigen receptor T-cell therapy in aged backgrounds. Aging Cell. 2021 02; 20(2):e13309.
Score: 0.126
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Sánchez-Fernández A, Zandee S, Amo-Aparicio J, Charabati M, Prat A, Garlanda C, Eisenmesser EZ, Dinarello CA, López-Vales R. IL-37 exerts therapeutic effects in experimental autoimmune encephalomyelitis through the receptor complex IL-1R5/IL-1R8. Theranostics. 2021; 11(1):1-13.
Score: 0.125
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Rønholt K, Nielsen AL, Johansen C, Vestergaard C, Fauerbye A, López-Vales R, Dinarello CA, Iversen L. IL-37 Expression Is Downregulated in Lesional Psoriasis Skin. Immunohorizons. 2020 11 25; 4(11):754-761.
Score: 0.124
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de Graaf DM, Jaeger M, van den Munckhof ICL, Ter Horst R, Schraa K, Zwaag J, Kox M, Fujita M, Yamauchi T, Mercurio L, Madonna S, Rutten JHW, de Graaf J, Riksen NP, van de Veerdonk FL, Netea MG, Joosten LAB, Dinarello CA. Reduced concentrations of the B cell cytokine interleukin 38 are associated with cardiovascular disease risk in overweight subjects. Eur J Immunol. 2021 03; 51(3):662-671.
Score: 0.124
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Amo-Aparicio J, Sanchez-Fernandez A, Li S, Eisenmesser EZ, Garlanda C, Dinarello CA, Lopez-Vales R. Extracellular and nuclear roles of IL-37 after spinal cord injury. Brain Behav Immun. 2021 01; 91:194-201.
Score: 0.123
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Dinarello CA. The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1. N Engl J Med. 2000 Sep 07; 343(10):732-4.
Score: 0.122
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Dinarello CA. Interleukin-18, a proinflammatory cytokine. Eur Cytokine Netw. 2000 Sep; 11(3):483-6.
Score: 0.122
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Dinarello CA. Proinflammatory cytokines. Chest. 2000 Aug; 118(2):503-8.
Score: 0.122
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Reznikov LL, Kim SH, Westcott JY, Frishman J, Fantuzzi G, Novick D, Rubinstein M, Dinarello CA. IL-18 binding protein increases spontaneous and IL-1-induced prostaglandin production via inhibition of IFN-gamma. Proc Natl Acad Sci U S A. 2000 Feb 29; 97(5):2174-9.
Score: 0.118
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Klück V, van Deuren RC, Cavalli G, Shaukat A, Arts P, Cleophas MC, Cri?an TO, Tausche AK, Riches P, Dalbeth N, Stamp LK, Hindmarsh JH, Jansen TLTA, Janssen M, Steehouwer M, Lelieveld S, van de Vorst M, Gilissen C, Dagna L, Van de Veerdonk FL, Eisenmesser EZ, Kim S, Merriman TR, Hoischen A, Netea MG, Dinarello CA, Joosten LA. Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout. Ann Rheum Dis. 2020 04; 79(4):536-544.
Score: 0.118
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Vidal-Vanaclocha F, Fantuzzi G, Mendoza L, Fuentes AM, Anasagasti MJ, Martín J, Carrascal T, Walsh P, Reznikov LL, Kim SH, Novick D, Rubinstein M, Dinarello CA. IL-18 regulates IL-1beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1. Proc Natl Acad Sci U S A. 2000 Jan 18; 97(2):734-9.
Score: 0.117
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Reznikov LL, Shames BD, Barton HA, Selzman CH, Fantuzzi G, Kim SH, Johnson SM, Dinarello CA. Interleukin-1beta deficiency results in reduced NF-kappaB levels in pregnant mice. Am J Physiol Regul Integr Comp Physiol. 2000 Jan; 278(1):R263-70.
Score: 0.117
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Ballak DB, Brunt VE, Sapinsley ZJ, Ziemba BP, Richey JJ, Zigler MC, Johnson LC, Gioscia-Ryan RA, Culp-Hill R, Eisenmesser EZ, D'Alessandro A, Dinarello CA, Seals DR. Short-term interleukin-37 treatment improves vascular endothelial function, endurance exercise capacity, and whole-body glucose metabolism in old mice. Aging Cell. 2020 01; 19(1):e13074.
Score: 0.116
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Mountford S, Ringleb A, Schwaiger R, Mayr D, Kobold S, Dinarello CA, Bufler P. Interleukin-37 Inhibits Colon Carcinogensis During Chronic Colitis. Front Immunol. 2019; 10:2632.
Score: 0.116
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Højen JF, Kristensen MLV, McKee AS, Wade MT, Azam T, Lunding LP, de Graaf DM, Swartzwelter BJ, Wegmann M, Tolstrup M, Beckman K, Fujita M, Fischer S, Dinarello CA. IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease. Nat Immunol. 2019 09; 20(9):1138-1149.
Score: 0.114
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Madonna S, Girolomoni G, Dinarello CA, Albanesi C. The Significance of IL-36 Hyperactivation and IL-36R Targeting in Psoriasis. Int J Mol Sci. 2019 Jul 05; 20(13).
Score: 0.113
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Dinarello CA. Is there an interleukin-1 genetic predisposition to developing severe sepsis? Crit Care Med. 1999 Jul; 27(7):1397-8.
Score: 0.113
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Osborne DG, Domenico J, Luo Y, Reid AL, Amato C, Zhai Z, Gao D, Ziman M, Dinarello CA, Robinson WA, Fujita M. Interleukin-37 is highly expressed in regulatory T cells of melanoma patients and enhanced by melanoma cell secretome. Mol Carcinog. 2019 09; 58(9):1670-1679.
Score: 0.112
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Reznikov LL, Fantuzzi G, Selzman CH, Shames BD, Barton HA, Bell H, McGregor JA, Dinarello CA. Utilization of endoscopic inoculation in a mouse model of intrauterine infection-induced preterm birth: role of interleukin 1beta. Biol Reprod. 1999 May; 60(5):1231-8.
Score: 0.111
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Mantovani A, Dinarello CA, Molgora M, Garlanda C. Interleukin-1 and Related Cytokines in the Regulation of Inflammation and Immunity. Immunity. 2019 04 16; 50(4):778-795.
Score: 0.111
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Puren AJ, Fantuzzi G, Dinarello CA. Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cells. Proc Natl Acad Sci U S A. 1999 Mar 02; 96(5):2256-61.
Score: 0.110
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Fantuzzi G, Dinarello CA. Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1). J Clin Immunol. 1999 Jan; 19(1):1-11.
Score: 0.109
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Reznikov LL, Puren AJ, Fantuzzi G, Mühl H, Shapiro L, Yoon DY, Cutler DL, Dinarello CA. Spontaneous and inducible cytokine responses in healthy humans receiving a single dose of IFN-alpha2b: increased production of interleukin-1 receptor antagonist and suppression of IL-1-induced IL-8. J Interferon Cytokine Res. 1998 Oct; 18(10):897-903.
Score: 0.107
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Dinarello CA. Interleukin-1 beta, interleukin-18, and the interleukin-1 beta converting enzyme. Ann N Y Acad Sci. 1998 Sep 29; 856:1-11.
Score: 0.107
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Kuipers EN, van Dam AD, Ballak DB, de Wit EA, Dinarello CA, Stienstra R, van Diepen JA, Rensen PCN, Boon MR. IL-37 Expression Reduces Lean Body Mass in Mice by Reducing Food Intake. Int J Mol Sci. 2018 Aug 02; 19(8).
Score: 0.106
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Yoon DY, Dinarello CA. Antibodies to domains II and III of the IL-1 receptor accessory protein inhibit IL-1 beta activity but not binding: regulation of IL-1 responses is via type I receptor, not the accessory protein. J Immunol. 1998 Apr 01; 160(7):3170-9.
Score: 0.103
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Barak V, Nisman B, Polliack A, Vannier E, Dinarello CA. Correlation of serum levels of interleukin-1 family members with disease activity and response to treatment in hairy cell leukemia. Eur Cytokine Netw. 1998 Mar; 9(1):33-9.
Score: 0.103
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Puren AJ, Fantuzzi G, Gu Y, Su MS, Dinarello CA. Interleukin-18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFalpha production from non-CD14+ human blood mononuclear cells. J Clin Invest. 1998 Feb 01; 101(3):711-21.
Score: 0.102
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van de Veerdonk FL, de Graaf DM, Joosten LA, Dinarello CA. Biology of IL-38 and its role in disease. Immunol Rev. 2018 01; 281(1):191-196.
Score: 0.102
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Dinarello CA. Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist. Int Rev Immunol. 1998; 16(5-6):457-99.
Score: 0.102
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Grabherr F, Grander C, Adolph TE, Wieser V, Mayr L, Enrich B, Macheiner S, Sangineto M, Reiter A, Viveiros A, Zoller H, Bufler P, Moschen AR, Dinarello CA, Tilg H. Ethanol-mediated suppression of IL-37 licenses alcoholic liver disease. Liver Int. 2018 06; 38(6):1095-1101.
Score: 0.101
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Dinarello CA. Interleukin-1. Cytokine Growth Factor Rev. 1997 Dec; 8(4):253-65.
Score: 0.101
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Dinarello CA. Blocking interleukin-1 and tumor necrosis factor in disease. Eur Cytokine Netw. 1997 Sep; 8(3):294-6.
Score: 0.099
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Hoeke G, Khedoe PPSJ, van Diepen JA, Pike-Overzet K, van de Ven B, Vazirpanah N, Mol I, Hiemstra PS, Staal FJT, Stienstra R, Netea MG, Dinarello CA, Rensen PCN, Berbée JFP. The Effects of Selective Hematopoietic Expression of Human IL-37 on Systemic Inflammation and Atherosclerosis in LDLr-Deficient Mice. Int J Mol Sci. 2017 Aug 09; 18(8).
Score: 0.099
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Fantuzzi G, Sacco S, Ghezzi P, Dinarello CA. Physiological and cytokine responses in IL-1 beta-deficient mice after zymosan-induced inflammation. Am J Physiol. 1997 Jul; 273(1 Pt 2):R400-6.
Score: 0.098
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Schauer AE, Klassert TE, von Lachner C, Riebold D, Schneeweiß A, Stock M, Müller MM, Hammerschmidt S, Bufler P, Seifert U, Dietert K, Dinarello CA, Nold MF, Gruber AD, Nold-Petry CA, Slevogt H. IL-37 Causes Excessive Inflammation and Tissue Damage in Murine Pneumococcal Pneumonia. J Innate Immun. 2017; 9(4):403-418.
Score: 0.098
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Dinarello CA. Induction of interleukin-1 and interleukin-1 receptor antagonist. Semin Oncol. 1997 Jun; 24(3 Suppl 9):S9-81-S9-93.
Score: 0.098
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Zhan Q, Zeng Q, Song R, Zhai Y, Xu D, Fullerton DA, Dinarello CA, Meng X. IL-37 suppresses MyD88-mediated inflammatory responses in human aortic valve interstitial cells. Mol Med. 2017 05; 23:83-91.
Score: 0.096
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Shapiro L, Dinarello CA. Hyperosmotic stress as a stimulant for proinflammatory cytokine production. Exp Cell Res. 1997 Mar 15; 231(2):354-62.
Score: 0.096
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Li J, Zhai Y, Ao L, Hui H, Fullerton DA, Dinarello CA, Meng X. Interleukin-37 suppresses the inflammatory response to protect cardiac function in old endotoxemic mice. Cytokine. 2017 07; 95:55-63.
Score: 0.096
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Roerink ME, van der Schaaf ME, Dinarello CA, Knoop H, van der Meer JW. Interleukin-1 as a mediator of fatigue in disease: a narrative review. J Neuroinflammation. 2017 01 21; 14(1):16.
Score: 0.095
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Clark BD, Ikejima T, Mancilla J, Orencole SF, Sirko SP, Ishii N, Okuda K, Dinarello CA. An antibody to a 17 amino acid synthetic peptide of the type I interleukin-1 receptor preferentially blocks interleukin-1 beta binding. J Interferon Cytokine Res. 1996 Dec; 16(12):1079-88.
Score: 0.094
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Pereira BJ, Sundaram S, Barrett TW, Butt NK, Porat R, King AJ, Dinarello CA. Transfer of cytokine-inducing bacterial products across hemodialyzer membranes in the presence of plasma or whole blood. Clin Nephrol. 1996 Dec; 46(6):394-401.
Score: 0.094
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Nowak KL, Chonchol M, Ikizler TA, Farmer-Bailey H, Salas N, Chaudhry R, Wang W, Smits G, Tengesdal I, Dinarello CA, Hung AM. IL-1 Inhibition and Vascular Function in CKD. J Am Soc Nephrol. 2017 Mar; 28(3):971-980.
Score: 0.093
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Cavalli G, Pappalardo F, Mangieri A, Dinarello CA, Dagna L, Tresoldi M. Treating Life-Threatening Myocarditis by Blocking Interleukin-1. Crit Care Med. 2016 Aug; 44(8):e751-4.
Score: 0.092
-
Fantuzzi G, Zheng H, Faggioni R, Benigni F, Ghezzi P, Sipe JD, Shaw AR, Dinarello CA. Effect of endotoxin in IL-1 beta-deficient mice. J Immunol. 1996 Jul 01; 157(1):291-6.
Score: 0.092
-
Van Tassell BW, Abouzaki NA, Oddi Erdle C, Carbone S, Trankle CR, Melchior RD, Turlington JS, Thurber CJ, Christopher S, Dixon DL, Fronk DT, Thomas CS, Rose SW, Buckley LF, Dinarello CA, Biondi-Zoccai G, Abbate A. Interleukin-1 Blockade in Acute Decompensated Heart Failure: A Randomized, Double-Blinded, Placebo-Controlled Pilot Study. J Cardiovasc Pharmacol. 2016 Jun; 67(6):544-51.
Score: 0.091
-
Lust JA, Lacy MQ, Zeldenrust SR, Witzig TE, Moon-Tasson LL, Dinarello CA, Donovan KA. Reduction in C-reactive protein indicates successful targeting of the IL-1/IL-6 axis resulting in improved survival in early stage multiple myeloma. Am J Hematol. 2016 06; 91(6):571-4.
Score: 0.090
-
Fantuzzi G, Dinarello CA. The inflammatory response in interleukin-1 beta-deficient mice: comparison with other cytokine-related knock-out mice. J Leukoc Biol. 1996 Apr; 59(4):489-93.
Score: 0.090
-
Dinarello CA. Biologic basis for interleukin-1 in disease. Blood. 1996 Mar 15; 87(6):2095-147.
Score: 0.090
-
Vidal-Vanaclocha F, Alvarez A, Asumendi A, Urcelay B, Tonino P, Dinarello CA. Interleukin 1 (IL-1)-dependent melanoma hepatic metastasis in vivo; increased endothelial adherence by IL-1-induced mannose receptors and growth factor production in vitro. J Natl Cancer Inst. 1996 Feb 21; 88(3-4):198-205.
Score: 0.089
-
Endres S, Whitaker RE, Ghorbani R, Meydani SN, Dinarello CA. Oral aspirin and ibuprofen increase cytokine-induced synthesis of IL-1 beta and of tumour necrosis factor-alpha ex vivo. Immunology. 1996 Feb; 87(2):264-70.
Score: 0.089
-
Coll-Miró M, Francos-Quijorna I, Santos-Nogueira E, Torres-Espin A, Bufler P, Dinarello CA, López-Vales R. Beneficial effects of IL-37 after spinal cord injury in mice. Proc Natl Acad Sci U S A. 2016 Feb 02; 113(5):1411-6.
Score: 0.089
-
Roerink ME, Knoop H, Bredie SJ, Heijnen M, Joosten LA, Netea MG, Dinarello CA, van der Meer JW. Cytokine inhibition in chronic fatigue syndrome patients: study protocol for a randomized controlled trial. Trials. 2015 Oct 05; 16:439.
Score: 0.087
-
Dinarello CA. Interleukin-1 and interleukin-1 receptor antagonist. Nutrition. 1995 Sep-Oct; 11(5 Suppl):492-4.
Score: 0.086
-
Dinarello CA. Controlling the production of interleukin-1 and tumor necrosis factor in disease. Nutrition. 1995 Sep-Oct; 11(5 Suppl):695-7.
Score: 0.086
-
Ballak DB, Stienstra R, Tack CJ, Dinarello CA, van Diepen JA. IL-1 family members in the pathogenesis and treatment of metabolic disease: Focus on adipose tissue inflammation and insulin resistance. Cytokine. 2015 Oct; 75(2):280-90.
Score: 0.086
-
Chernoff AE, Granowitz EV, Shapiro L, Vannier E, Lonnemann G, Angel JB, Kennedy JS, Rabson AR, Wolff SM, Dinarello CA. A randomized, controlled trial of IL-10 in humans. Inhibition of inflammatory cytokine production and immune responses. J Immunol. 1995 May 15; 154(10):5492-9.
Score: 0.085
-
Højen JF, Rasmussen TA, Andersen KL, Winckelmann AA, Laursen RR, Gunst JD, Møller HJ, Fujita M, Østergaard L, Søgaard OS, Dinarello CA, Tolstrup M. Interleukin-37 Expression Is Increased in Chronic HIV-1-Infected Individuals and Is Associated with Inflammation and the Size of the Total Viral Reservoir. Mol Med. 2015 Apr 14; 21:337-45.
Score: 0.084
-
Nold-Petry CA, Lo CY, Rudloff I, Elgass KD, Li S, Gantier MP, Lotz-Havla AS, Gersting SW, Cho SX, Lao JC, Ellisdon AM, Rotter B, Azam T, Mangan NE, Rossello FJ, Whisstock JC, Bufler P, Garlanda C, Mantovani A, Dinarello CA, Nold MF. IL-37 requires the receptors IL-18Ra and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction. Nat Immunol. 2015 Apr; 16(4):354-65.
Score: 0.084
-
Lonnemann G, Shapiro L, Engler-Blum G, Müller GA, Koch KM, Dinarello CA. Cytokines in human renal interstitial fibrosis. I. Interleukin-1 is a paracrine growth factor for cultured fibrosis-derived kidney fibroblasts. Kidney Int. 1995 Mar; 47(3):837-44.
Score: 0.083
-
Lonnemann G, Engler-Blum G, Müller GA, Koch KM, Dinarello CA. Cytokines in human renal interstitial fibrosis. II. Intrinsic interleukin (IL)-1 synthesis and IL-1-dependent production of IL-6 and IL-8 by cultured kidney fibroblasts. Kidney Int. 1995 Mar; 47(3):845-54.
Score: 0.083
-
Dinarello CA. Interleukin-1 and interleukin-1 receptor antagonist production during haemodialysis: which cytokine is a surrogate marker for dialysis-related complications? Nephrol Dial Transplant. 1995; 10 Suppl 3:25-8.
Score: 0.083
-
Kaplanski G, Farnarier C, Kaplanski S, Porat R, Shapiro L, Bongrand P, Dinarello CA. Interleukin-1 induces interleukin-8 secretion from endothelial cells by a juxtacrine mechanism. Blood. 1994 Dec 15; 84(12):4242-8.
Score: 0.082
-
Netea MG, van de Veerdonk FL, van der Meer JW, Dinarello CA, Joosten LA. Inflammasome-independent regulation of IL-1-family cytokines. Annu Rev Immunol. 2015; 33:49-77.
Score: 0.082
-
Dinarello CA. The interleukin-1 family: 10 years of discovery. FASEB J. 1994 Dec; 8(15):1314-25.
Score: 0.082
-
Moretti S, Bozza S, Oikonomou V, Renga G, Casagrande A, Iannitti RG, Puccetti M, Garlanda C, Kim S, Li S, van de Veerdonk FL, Dinarello CA, Romani L. IL-37 inhibits inflammasome activation and disease severity in murine aspergillosis. PLoS Pathog. 2014 Nov; 10(11):e1004462.
Score: 0.082
-
Dinarello CA. To Sheldon M. Wolff, as we commemorate the 10th anniversary of the clonings of IL-1 alpha and IL-1 beta. Eur Cytokine Netw. 1994 Nov-Dec; 5(6):513-6.
Score: 0.082
-
Dinarello CA. The biological properties of interleukin-1. Eur Cytokine Netw. 1994 Nov-Dec; 5(6):517-31.
Score: 0.082
-
Shapiro L, Panayotatos N, Meydani SN, Wu D, Dinarello CA. Ciliary neurotrophic factor combined with soluble receptor inhibits synthesis of proinflammatory cytokines and prostaglandin-E2 in vitro. Exp Cell Res. 1994 Nov; 215(1):51-6.
Score: 0.082
-
Luo Y, Cai X, Liu S, Wang S, Nold-Petry CA, Nold MF, Bufler P, Norris D, Dinarello CA, Fujita M. Suppression of antigen-specific adaptive immunity by IL-37 via induction of tolerogenic dendritic cells. Proc Natl Acad Sci U S A. 2014 Oct 21; 111(42):15178-83.
Score: 0.081
-
Dinarello CA. Interleukin-1 antagonists. J Interferon Res. 1994 Oct; 14(5):307.
Score: 0.081
-
Ballak DB, van Diepen JA, Moschen AR, Jansen HJ, Hijmans A, Groenhof GJ, Leenders F, Bufler P, Boekschoten MV, Müller M, Kersten S, Li S, Kim S, Eini H, Lewis EC, Joosten LA, Tilg H, Netea MG, Tack CJ, Dinarello CA, Stienstra R. IL-37 protects against obesity-induced inflammation and insulin resistance. Nat Commun. 2014 Sep 03; 5:4711.
Score: 0.081
-
Dinarello CA. Interleukin-1 in disease. Keio J Med. 1994 Sep; 43(3):131-6.
Score: 0.081
-
Wakabayashi G, Cannon JG, Gelfand JA, Clark BD, Aiura K, Burke JF, Wolff SM, Dinarello CA. Altered interleukin-1 and tumor necrosis factor production and secretion during pyrogenic tolerance to LPS in rabbits. Am J Physiol. 1994 Jul; 267(1 Pt 2):R329-36.
Score: 0.080
-
Dinarello CA. Is there a role for interleukin-1 blockade in intravenous immunoglobulin therapy? Immunol Rev. 1994 Jun; 139:173-88.
Score: 0.079
-
Vannier E, Dinarello CA. Histamine enhances interleukin (IL)-1-induced IL-6 gene expression and protein synthesis via H2 receptors in peripheral blood mononuclear cells. J Biol Chem. 1994 Apr 01; 269(13):9952-6.
Score: 0.078
-
Pereira BJ, Shapiro L, King AJ, Falagas ME, Strom JA, Dinarello CA. Plasma levels of IL-1 beta, TNF alpha and their specific inhibitors in undialyzed chronic renal failure, CAPD and hemodialysis patients. Kidney Int. 1994 Mar; 45(3):890-6.
Score: 0.078
-
Bulau AM, Nold MF, Li S, Nold-Petry CA, Fink M, Mansell A, Schwerd T, Hong J, Rubartelli A, Dinarello CA, Bufler P. Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses. Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7):2650-5.
Score: 0.077
-
Schirò R, Longoni D, Rossi V, Maglia O, Doni A, Arsura M, Carrara G, Masera G, Vannier E, Dinarello CA, et al. Suppression of juvenile chronic myelogenous leukemia colony growth by interleukin-1 receptor antagonist. Blood. 1994 Jan 15; 83(2):460-5.
Score: 0.077
-
Dinarello CA. Blocking interleukin-1 receptors. Int J Clin Lab Res. 1994; 24(2):61-79.
Score: 0.077
-
Pereira BJ, King AJ, Falagas ME, Dinarello CA. Interleukin-1 receptor antagonist: an index of dialysis-induced interleukin-1 production. Nephron. 1994; 67(3):358-61.
Score: 0.077
-
Dinarello CA. Interleukin-1. Adv Pharmacol. 1994; 25:21-51.
Score: 0.077
-
Poutsiaka DD, Mengozzi M, Vannier E, Sinha B, Dinarello CA. Cross-linking of the beta-glucan receptor on human monocytes results in interleukin-1 receptor antagonist but not interleukin-1 production. Blood. 1993 Dec 15; 82(12):3695-700.
Score: 0.077
-
Garlanda C, Dinarello CA, Mantovani A. The interleukin-1 family: back to the future. Immunity. 2013 Dec 12; 39(6):1003-18.
Score: 0.077
-
Tilg H, Vogel W, Wiedermann CJ, Shapiro L, Herold M, Judmaier G, Dinarello CA. Circulating interleukin-1 and tumor necrosis factor antagonists in liver disease. Hepatology. 1993 Nov; 18(5):1132-8.
Score: 0.076
-
Van Tassell BW, Arena R, Biondi-Zoccai G, Canada JM, Oddi C, Abouzaki NA, Jahangiri A, Falcao RA, Kontos MC, Shah KB, Voelkel NF, Dinarello CA, Abbate A. Effects of interleukin-1 blockade with anakinra on aerobic exercise capacity in patients with heart failure and preserved ejection fraction (from the D-HART pilot study). Am J Cardiol. 2014 Jan 15; 113(2):321-327.
Score: 0.076
-
Hara N, Alkanani AK, Dinarello CA, Zipris D. Modulation of virus-induced innate immunity and type 1 diabetes by IL-1 blockade. Innate Immun. 2014 Aug; 20(6):574-84.
Score: 0.076
-
Aiura K, Gelfand JA, Burke JF, Thompson RC, Dinarello CA. Interleukin-1 (IL-1) receptor antagonist prevents Staphylococcus epidermidis-induced hypotension and reduces circulating levels of tumor necrosis factor and IL-1 beta in rabbits. Infect Immun. 1993 Aug; 61(8):3342-50.
Score: 0.075
-
Pereira BJ, King AJ, Poutsiaka DD, Strom JA, Dinarello CA. Comparison of first use and reuse of cuprophan membranes on interleukin-1 receptor antagonist and interleukin-1 beta production by blood mononuclear cells. Am J Kidney Dis. 1993 Aug; 22(2):288-95.
Score: 0.075
-
Vannier E, Dinarello CA. Histamine enhances interleukin (IL)-1-induced IL-1 gene expression and protein synthesis via H2 receptors in peripheral blood mononuclear cells. Comparison with IL-1 receptor antagonist. J Clin Invest. 1993 Jul; 92(1):281-7.
Score: 0.074
-
Dinarello CA. Modalities for reducing interleukin 1 activity in disease. Immunol Today. 1993 Jun; 14(6):260-4.
Score: 0.074
-
Kaplanski G, Porat R, Aiura K, Erban JK, Gelfand JA, Dinarello CA. Activated platelets induce endothelial secretion of interleukin-8 in vitro via an interleukin-1-mediated event. Blood. 1993 May 15; 81(10):2492-5.
Score: 0.074
-
Dinarello CA. Modalities for reducing interleukin 1 activity in disease. Trends Pharmacol Sci. 1993 May; 14(5):155-9.
Score: 0.074
-
Dinarello CA, Wolff SM. The role of interleukin-1 in disease. N Engl J Med. 1993 Jan 14; 328(2):106-13.
Score: 0.072
-
Dinarello CA. Blocking interleukin-1 in disease. Blood Purif. 1993; 11(2):118-27.
Score: 0.072
-
Dinarello CA. Interleukin-1 and tumor necrosis factor and their naturally occurring antagonists during hemodialysis. Kidney Int Suppl. 1992 Oct; 38:S68-77.
Score: 0.071
-
Dinarello CA. The role of interleukin-1 in host responses to infectious diseases. Infect Agents Dis. 1992 Oct; 1(5):227-36.
Score: 0.071
-
Cannon JG, Friedberg JS, Gelfand JA, Tompkins RG, Burke JF, Dinarello CA. Circulating interleukin-1 beta and tumor necrosis factor-alpha concentrations after burn injury in humans. Crit Care Med. 1992 Oct; 20(10):1414-9.
Score: 0.071
-
Miller LC, Isa S, Vannier E, Georgilis K, Steere AC, Dinarello CA. Live Borrelia burgdorferi preferentially activate interleukin-1 beta gene expression and protein synthesis over the interleukin-1 receptor antagonist. J Clin Invest. 1992 Sep; 90(3):906-12.
Score: 0.070
-
Granowitz EV, Porat R, Mier JW, Pribble JP, Stiles DM, Bloedow DC, Catalano MA, Wolff SM, Dinarello CA. Pharmacokinetics, safety and immunomodulatory effects of human recombinant interleukin-1 receptor antagonist in healthy humans. Cytokine. 1992 Sep; 4(5):353-60.
Score: 0.070
-
Mancilla J, Ikejima T, Dinarello CA. Glycosylation of the interleukin-1 receptor type I is required for optimal binding of interleukin-1. Lymphokine Cytokine Res. 1992 Aug; 11(4):197-205.
Score: 0.070
-
Katzen NA, Segal GM, Vannier E, Nerad JL, Klempner MS, Dinarello CA. Comparison of granulocyte-macrophage colony stimulating factor and interleukin-1 production from human peripheral blood mononuclear cells as measured by specific radioimmunoassays. Eur Cytokine Netw. 1992 Jul-Aug; 3(4):365-72.
Score: 0.069
-
Dinarello CA. Interleukin-1 and tumor necrosis factor: effector cytokines in autoimmune diseases. Semin Immunol. 1992 Jun; 4(3):133-45.
Score: 0.069
-
Dinarello CA. Role of interleukin-1 in infectious diseases. Immunol Rev. 1992 Jun; 127:119-46.
Score: 0.069
-
Dinarello CA. Dissociation of transcription from translation of human IL-1 beta: induction of steady state mRNA by adherence or recombinant C5a in the absence of translation. Proc Soc Exp Biol Med. 1992 Jun; 200(2):228-32.
Score: 0.069
-
Vannier E, Miller LC, Dinarello CA. Coordinated antiinflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist. Proc Natl Acad Sci U S A. 1992 May 01; 89(9):4076-80.
Score: 0.069
-
Granowitz EV, Clark BD, Vannier E, Callahan MV, Dinarello CA. Effect of interleukin-1 (IL-1) blockade on cytokine synthesis: I. IL-1 receptor antagonist inhibits IL-1-induced cytokine synthesis and blocks the binding of IL-1 to its type II receptor on human monocytes. Blood. 1992 May 01; 79(9):2356-63.
Score: 0.069
-
Dinarello CA. ELISA kits based on monoclonal antibodies do not measure total IL-1 beta synthesis. J Immunol Methods. 1992 Apr 08; 148(1-2):255-9.
Score: 0.068
-
Romero R, Mazor M, Brandt F, Sepulveda W, Avila C, Cotton DB, Dinarello CA. Interleukin-1 alpha and interleukin-1 beta in preterm and term human parturition. Am J Reprod Immunol. 1992 Apr-May; 27(3-4):117-23.
Score: 0.068
-
Porat R, Poutsiaka DD, Miller LC, Granowitz EV, Dinarello CA. Interleukin-1 (IL-1) receptor blockade reduces endotoxin and Borrelia burgdorferi-stimulated IL-8 synthesis in human mononuclear cells. FASEB J. 1992 Apr; 6(7):2482-6.
Score: 0.068
-
Ye K, Koch KC, Clark BD, Dinarello CA. Interleukin-1 down-regulates gene and surface expression of interleukin-1 receptor type I by destabilizing its mRNA whereas interleukin-2 increases its expression. Immunology. 1992 Mar; 75(3):427-34.
Score: 0.068
-
van de Veerdonk FL, Stoeckman AK, Wu G, Boeckermann AN, Azam T, Netea MG, Joosten LA, van der Meer JW, Hao R, Kalabokis V, Dinarello CA. IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):3001-5.
Score: 0.068
-
Dinarello CA. Reduction of inflammation by decreasing production of interleukin-1 or by specific receptor antagonism. Int J Tissue React. 1992; 14(2):65-75.
Score: 0.067
-
Koch KC, Ye K, Clark BD, Dinarello CA. Interleukin 4 (IL) 4 up-regulates gene and surface IL 1 receptor type I in murine T helper type 2 cells. Eur J Immunol. 1992 Jan; 22(1):153-7.
Score: 0.067
-
Dinarello CA. The biology of interleukin-1. Chem Immunol. 1992; 51:1-32.
Score: 0.067
-
Granowitz EV, Santos AA, Poutsiaka DD, Cannon JG, Wilmore DW, Wolff SM, Dinarello CA. Production of interleukin-1-receptor antagonist during experimental endotoxaemia. Lancet. 1991 Dec 07; 338(8780):1423-4.
Score: 0.067
-
Dinarello CA. Inflammatory cytokines: interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases. Curr Opin Immunol. 1991 Dec; 3(6):941-8.
Score: 0.067
-
Clark BD, Bedrosian I, Schindler R, Cominelli F, Cannon JG, Shaw AR, Dinarello CA. Detection of interleukin 1 alpha and 1 beta in rabbit tissues during endotoxemia using sensitive radioimmunoassays. J Appl Physiol (1985). 1991 Dec; 71(6):2412-8.
Score: 0.067
-
Barak V, Peritt D, Flechner I, Yanai P, Halperin T, Treves AJ, Dinarello CA. The specific IL-1 inhibitor from the human M20 cell line is distinct from the IL-1 receptor antagonist. Lymphokine Cytokine Res. 1991 Dec; 10(6):437-42.
Score: 0.067
-
Bedrosian I, Sofia RD, Wolff SM, Dinarello CA. Taurolidine, an analogue of the amino acid taurine, suppresses interleukin 1 and tumor necrosis factor synthesis in human peripheral blood mononuclear cells. Cytokine. 1991 Nov; 3(6):568-75.
Score: 0.066
-
Dinarello CA, Thompson RC. Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro. Immunol Today. 1991 Nov; 12(11):404-10.
Score: 0.066
-
Porat R, Clark BD, Wolff SM, Dinarello CA. Enhancement of growth of virulent strains of Escherichia coli by interleukin-1. Science. 1991 Oct 18; 254(5030):430-2.
Score: 0.066
-
Poutsiaka DD, Clark BD, Vannier E, Dinarello CA. Production of interleukin-1 receptor antagonist and interleukin-1 beta by peripheral blood mononuclear cells is differentially regulated. Blood. 1991 Sep 01; 78(5):1275-81.
Score: 0.066
-
McNamee EN, Masterson JC, Jedlicka P, McManus M, Grenz A, Collins CB, Nold MF, Nold-Petry C, Bufler P, Dinarello CA, Rivera-Nieves J. Interleukin 37 expression protects mice from colitis. Proc Natl Acad Sci U S A. 2011 Oct 04; 108(40):16711-6.
Score: 0.065
-
Granowitz EV, Clark BD, Mancilla J, Dinarello CA. Interleukin-1 receptor antagonist competitively inhibits the binding of interleukin-1 to the type II interleukin-1 receptor. J Biol Chem. 1991 Aug 05; 266(22):14147-50.
Score: 0.065
-
Wakabayashi G, Gelfand JA, Jung WK, Connolly RJ, Burke JF, Dinarello CA. Staphylococcus epidermidis induces complement activation, tumor necrosis factor and interleukin-1, a shock-like state and tissue injury in rabbits without endotoxemia. Comparison to Escherichia coli. J Clin Invest. 1991 Jun; 87(6):1925-35.
Score: 0.064
-
Belizario JE, Dinarello CA. Interleukin 1, interleukin 6, tumor necrosis factor, and transforming growth factor beta increase cell resistance to tumor necrosis factor cytotoxicity by growth arrest in the G1 phase of the cell cycle. Cancer Res. 1991 May 01; 51(9):2379-85.
Score: 0.064
-
Dinarello CA. Interleukin-1 and interleukin-1 antagonism. Blood. 1991 Apr 15; 77(8):1627-52.
Score: 0.064
-
Wakabayashi G, Gelfand JA, Burke JF, Thompson RC, Dinarello CA. A specific receptor antagonist for interleukin 1 prevents Escherichia coli-induced shock in rabbits. FASEB J. 1991 Mar 01; 5(3):338-43.
Score: 0.063
-
Sirko SP, Schindler R, Doyle MJ, Weisman SM, Dinarello CA. Transcription, translation and secretion of interleukin 1 and tumor necrosis factor: effects of tebufelone, a dual cyclooxygenase/5-lipoxygenase inhibitor. Eur J Immunol. 1991 Feb; 21(2):243-50.
Score: 0.063
-
Miller LC, Isa S, LoPreste G, Schaller JG, Dinarello CA. Neonatal interleukin-1 beta, interleukin-6, and tumor necrosis factor: cord blood levels and cellular production. J Pediatr. 1990 Dec; 117(6):961-5.
Score: 0.062
-
Hauser SL, Doolittle TH, Lincoln R, Brown RH, Dinarello CA. Cytokine accumulations in CSF of multiple sclerosis patients: frequent detection of interleukin-1 and tumor necrosis factor but not interleukin-6. Neurology. 1990 Nov; 40(11):1735-9.
Score: 0.062
-
Schindler R, Gelfand JA, Dinarello CA. Recombinant C5a stimulates transcription rather than translation of interleukin-1 (IL-1) and tumor necrosis factor: translational signal provided by lipopolysaccharide or IL-1 itself. Blood. 1990 Oct 15; 76(8):1631-8.
Score: 0.062
-
Zucali JR, Morse C, Dinarello CA. The role of protein kinase C in interleukin 1 and tumor necrosis factor alpha induction of fibroblasts to produce and release granulocyte-macrophage colony-stimulating activity. Exp Hematol. 1990 Sep; 18(8):888-92.
Score: 0.061
-
Cominelli F, Nast CC, Clark BD, Schindler R, Lierena R, Eysselein VE, Thompson RC, Dinarello CA. Interleukin 1 (IL-1) gene expression, synthesis, and effect of specific IL-1 receptor blockade in rabbit immune complex colitis. J Clin Invest. 1990 Sep; 86(3):972-80.
Score: 0.061
-
Ikejima T, Okusawa S, Ghezzi P, van der Meer JW, Dinarello CA. Interleukin-1 induces tumor necrosis factor (TNF) in human peripheral blood mononuclear cells in vitro and a circulating TNF-like activity in rabbits. J Infect Dis. 1990 Jul; 162(1):215-23.
Score: 0.060
-
Munoz C, Endres S, van der Meer J, Schlesinger L, Arevalo M, Dinarello C. Interleukin-1 beta in human colostrum. Res Immunol. 1990 Jul-Aug; 141(6):505-13.
Score: 0.060
-
Schindler R, Clark BD, Dinarello CA. Dissociation between interleukin-1 beta mRNA and protein synthesis in human peripheral blood mononuclear cells. J Biol Chem. 1990 Jun 25; 265(18):10232-7.
Score: 0.060
-
Heinhuis B, Koenders MI, van de Loo FA, van Lent PL, Kim SH, Dinarello CA, Joosten LA, van den Berg WB. IL-32gamma and Streptococcus pyogenes cell wall fragments synergise for IL-1-dependent destructive arthritis via upregulation of TLR-2 and NOD2. Ann Rheum Dis. 2010 Oct; 69(10):1866-72.
Score: 0.060
-
Schindler R, Ghezzi P, Dinarello CA. IL-1 induces IL-1. IV. IFN-gamma suppresses IL-1 but not lipopolysaccharide-induced transcription of IL-1. J Immunol. 1990 Mar 15; 144(6):2216-22.
Score: 0.059
-
Dinarello CA. Interleukin-1 and inhibition of interleukin-1 in hemodialysis patients. Contrib Nephrol. 1990; 86:48-69; discussion 69-72.
Score: 0.058
-
Dinarello CA, Endres S, Meydani SN, Meydani M, Hellerstein MK. Interleukin-1, anorexia, and dietary fatty acids. Ann N Y Acad Sci. 1990; 587:332-8.
Score: 0.058
-
Dinarello CA, Schindler R. Dissociation of transcription from translation of human IL-1-beta: the induction of steady state mRNA by adherence or recombinant C5a in the absence of translation. Prog Clin Biol Res. 1990; 349:195-204.
Score: 0.058
-
Schindler R, Mancilla J, Endres S, Ghorbani R, Clark SC, Dinarello CA. Correlations and interactions in the production of interleukin-6 (IL-6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF. Blood. 1990 Jan 01; 75(1):40-7.
Score: 0.058
-
Schindler R, Lonnemann G, Shaldon S, Koch KM, Dinarello CA. Transcription, not synthesis, of interleukin-1 and tumor necrosis factor by complement. Kidney Int. 1990 Jan; 37(1):85-93.
Score: 0.058
-
Endres S, Cannon JG, Ghorbani R, Dempsey RA, Sisson SD, Lonnemann G, Van der Meer JW, Wolff SM, Dinarello CA. In vitro production of IL 1 beta, IL 1 alpha, TNF and IL2 in healthy subjects: distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation. Eur J Immunol. 1989 Dec; 19(12):2327-33.
Score: 0.058
-
Joosten LA, Netea MG, Fantuzzi G, Koenders MI, Helsen MM, Sparrer H, Pham CT, van der Meer JW, Dinarello CA, van den Berg WB. Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta. Arthritis Rheum. 2009 Dec; 60(12):3651-62.
Score: 0.058
-
Dinarello CA. The endogenous pyrogens in host-defense interactions. Hosp Pract (Off Ed). 1989 Nov 15; 24(11):111-5, 118, 121 passim.
Score: 0.058
-
Orencole SF, Dinarello CA. Characterization of a subclone (D10S) of the D10.G4.1 helper T-cell line which proliferates to attomolar concentrations of interleukin-1 in the absence of mitogens. Cytokine. 1989 Nov; 1(1):14-22.
Score: 0.058
-
Savage N, Puren AJ, Orencole SF, Ikejima T, Clark BD, Dinarello CA. Studies on IL-1 receptors on D10S T-helper cells: demonstration of two molecularly and antigenically distinct IL-1 binding proteins. Cytokine. 1989 Nov; 1(1):23-35.
Score: 0.058
-
Lonnemann G, Endres S, Van der Meer JW, Cannon JG, Koch KM, Dinarello CA. Differences in the synthesis and kinetics of release of interleukin 1 alpha, interleukin 1 beta and tumor necrosis factor from human mononuclear cells. Eur J Immunol. 1989 Sep; 19(9):1531-6.
Score: 0.057
-
Fibbe WE, van der Meer JW, Falkenburg JH, Hamilton MS, Kluin PM, Dinarello CA. A single low dose of human recombinant interleukin 1 accelerates the recovery of neutrophils in mice with cyclophosphamide-induced neutropenia. Exp Hematol. 1989 Aug; 17(7):805-8.
Score: 0.057
-
Hellerstein MK, Meydani SN, Meydani M, Wu K, Dinarello CA. Interleukin-1-induced anorexia in the rat. Influence of prostaglandins. J Clin Invest. 1989 Jul; 84(1):228-35.
Score: 0.056
-
Ben-Sasson SZ, Hu-Li J, Quiel J, Cauchetaux S, Ratner M, Shapira I, Dinarello CA, Paul WE. IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation. Proc Natl Acad Sci U S A. 2009 Apr 28; 106(17):7119-24.
Score: 0.056
-
Dinarello CA, Endres S. Role for interleukin-1 in the pathogenesis of hypersensitivity diseases. J Cell Biochem. 1989 Mar; 39(3):229-38.
Score: 0.055
-
Dinarello CA, Clark BD, Puren AJ, Savage N, Rosoff PM. The interleukin 1 receptor. Immunol Today. 1989 Feb; 10(2):49-51.
Score: 0.055
-
Konnikov N, Pincus SH, Dinarello CA. Elevated plasma interleukin-1 levels in humans following ultraviolet light therapy for psoriasis. J Invest Dermatol. 1989 Feb; 92(2):235-9.
Score: 0.055
-
Schindler R, Dinarello CA. A method for removing interleukin-1- and tumor necrosis factor-inducing substances from bacterial cultures by ultrafiltration with polysulfone. J Immunol Methods. 1989 Jan 17; 116(2):159-65.
Score: 0.055
-
Dinarello CA. Interleukin-1 and its biologically related cytokines. Adv Immunol. 1989; 44:153-205.
Score: 0.054
-
Schindler R, Ghezzi P, Dinarello CA. Interferons as inhibitors of interleukin 1 induced interleukin 1 synthesis. Lymphokine Res. 1989; 8(3):275-80.
Score: 0.054
-
Dinarello CA, Okusawa S, Gelfand JA. Interleukin-1 induces a shock-like state in rabbits: synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition. Prog Clin Biol Res. 1989; 286:243-63.
Score: 0.054
-
Dinarello CA. Interleukin-1 and the effects of cyclooxygenase inhibitors on its biological activities. Bull N Y Acad Med. 1989 Jan; 65(1):80-92.
Score: 0.054
-
Dinarello CA, Savage N. Interleukin-1 and its receptor. Crit Rev Immunol. 1989; 9(1):1-20.
Score: 0.054
-
Dinarello CA, Orencole SF, Savage N. Interleukin-1 induced T-lymphocyte proliferation and its relation to IL-1 receptors. Adv Exp Med Biol. 1989; 254:45-53.
Score: 0.054
-
van der Meer JW, Rubin RH, Pasternack M, Medearis DN, Lynch P, Dinarello CA. The in vivo and in vitro effects of interleukin-1 and tumor necrosis factor on murine cytomegalovirus infection. Biotherapy. 1989; 1(3):227-31.
Score: 0.054
-
Dinarello CA, Neta R. An overview on interleukin-1 as a therapeutic agent. Biotherapy. 1989; 1(4):245-54.
Score: 0.054
-
Cominelli F, Dinarello CA. Interleukin-1 in the pathogenesis of and protection from inflammatory bowel disease. Biotherapy. 1989; 1(4):369-75.
Score: 0.054
-
Schindler R, Lonnemann G, Shaldon S, Koch KM, Dinarello CA. Induction of interleukin-1 and tumor necrosis factor during in vitro hemodialysis with different membranes. Contrib Nephrol. 1989; 74:58-65.
Score: 0.054
-
Dinarello CA, Okusawa S, Gelfand JA. Interleukin-1 induces a shock-like state in rabbits: synergism with tumor necrosis factor and the effect of ibuprofen. Prog Clin Biol Res. 1989; 299:203-15.
Score: 0.054
-
Endres S, Ghorbani R, Lonnemann G, van der Meer JW, Dinarello CA. Measurement of immunoreactive interleukin-1 beta from human mononuclear cells: optimization of recovery, intrasubject consistency, and comparison with interleukin-1 alpha and tumor necrosis factor. Clin Immunol Immunopathol. 1988 Dec; 49(3):424-38.
Score: 0.054
-
Schweizer A, Feige U, Fontana A, Müller K, Dinarello CA. Interleukin-1 enhances pain reflexes. Mediation through increased prostaglandin E2 levels. Agents Actions. 1988 Dec; 25(3-4):246-51.
Score: 0.054
-
Ikejima T, Okusawa S, van der Meer JW, Dinarello CA. Induction by toxic-shock-syndrome toxin-1 of a circulating tumor necrosis factor-like substance in rabbits and of immunoreactive tumor necrosis factor and interleukin-1 from human mononuclear cells. J Infect Dis. 1988 Nov; 158(5):1017-25.
Score: 0.054
-
Sisson SD, Dinarello CA. Production of interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor by human mononuclear cells stimulated with granulocyte-macrophage colony-stimulating factor. Blood. 1988 Oct; 72(4):1368-74.
Score: 0.054
-
Rosoff PM, Savage N, Dinarello CA. Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanism. Cell. 1988 Jul 01; 54(1):73-81.
Score: 0.053
-
Lonnemann G, Koch KM, Shaldon S, Dinarello CA. Studies on the ability of hemodialysis membranes to induce, bind, and clear human interleukin-1. J Lab Clin Med. 1988 Jul; 112(1):76-86.
Score: 0.053
-
Van't Wout JW, Van der Meer JW, Barza M, Dinarello CA. Protection of neutropenic mice from lethal Candida albicans infection by recombinant interleukin 1. Eur J Immunol. 1988 Jul; 18(7):1143-6.
Score: 0.053
-
Ghezzi P, Dinarello CA. IL-1 induces IL-1. III. Specific inhibition of IL-1 production by IFN-gamma. J Immunol. 1988 Jun 15; 140(12):4238-44.
Score: 0.052
-
Coceani F, Lees J, Dinarello CA. Occurrence of interleukin-1 in cerebrospinal fluid of the conscious cat. Brain Res. 1988 Apr 19; 446(2):245-50.
Score: 0.052
-
Sharma S, Kulk N, Nold MF, Gräf R, Kim SH, Reinhardt D, Dinarello CA, Bufler P. The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines. J Immunol. 2008 Apr 15; 180(8):5477-82.
Score: 0.052
-
Okusawa S, Gelfand JA, Ikejima T, Connolly RJ, Dinarello CA. Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition. J Clin Invest. 1988 Apr; 81(4):1162-72.
Score: 0.052
-
van der Meer JW, Barza M, Wolff SM, Dinarello CA. A low dose of recombinant interleukin 1 protects granulocytopenic mice from lethal gram-negative infection. Proc Natl Acad Sci U S A. 1988 Mar; 85(5):1620-3.
Score: 0.051
-
Dinarello CA. Interleukin-1. Dig Dis Sci. 1988 Mar; 33(3 Suppl):25S-35S.
Score: 0.051
-
Dinarello CA, Koch KM, Shaldon S. Interleukin-1 and its relevance in patients treated with hemodialysis. Kidney Int Suppl. 1988 Mar; 24:S21-6.
Score: 0.051
-
Dinarello CA. Biology of interleukin 1. FASEB J. 1988 Feb; 2(2):108-15.
Score: 0.051
-
Dinarello CA. Interleukin-1. Ann N Y Acad Sci. 1988; 546:122-32.
Score: 0.051
-
Shaldon S, Koch KM, Dinarello CA. Interleukin-1 activation and acute phase response during hemodialysis. Contrib Nephrol. 1988; 61:18-26.
Score: 0.051
-
Cannon JG, van der Meer JW, Kwiatkowski D, Endres S, Lonnemann G, Burke JF, Dinarello CA. Interleukin-1 beta in human plasma: optimization of blood collection, plasma extraction, and radioimmunoassay methods. Lymphokine Res. 1988; 7(4):457-67.
Score: 0.051
-
Lonnemann G, Endres S, van der Meer JW, Cannon JG, Dinarello CA. A radioimmunoassay for human interleukin-1 alpha: measurement of IL-1 alpha produced in vitro by human blood mononuclear cells stimulated with endotoxin. Lymphokine Res. 1988; 7(2):75-84.
Score: 0.051
-
Dinarello CA. Endogenous pyrogens. Methods Enzymol. 1988; 163:495-510.
Score: 0.051
-
Conti P, Reale M, Fiore S, Cancelli A, Angeletti PU, Dinarello CA. Recombinant interleukin 1 and tumor necrosis factor acting in synergy to release thromboxane, 6-KETO-PGF1 alpha and PGE2 by human neutrophils. Scand J Rheumatol Suppl. 1988; 75:318-24.
Score: 0.051
-
Lonnemann G, Bingel M, Floege J, Koch KM, Shaldon S, Dinarello CA. Detection of endotoxin-like interleukin-1-inducing activity during in vitro dialysis. Kidney Int. 1988 Jan; 33(1):29-35.
Score: 0.051
-
Dinarello CA. Interleukin-1--its multiple biological effects and its association with hemodialysis. Blood Purif. 1988; 6(3):164-72.
Score: 0.051
-
Endres S, van der Meer JW, Dinarello CA. Interleukin-1 in the pathogenesis of fever. Eur J Clin Invest. 1987 Dec; 17(6):469-74.
Score: 0.051
-
Dinarello CA. The biology of interleukin 1 and comparison to tumor necrosis factor. Immunol Lett. 1987 Dec; 16(3-4):227-31.
Score: 0.051
-
Movat HZ, Burrowes CE, Cybulsky MI, Dinarello CA. Acute inflammation and a Shwartzman-like reaction induced by interleukin-1 and tumor necrosis factor. Synergistic action of the cytokines in the induction of inflammation and microvascular injury. Am J Pathol. 1987 Dec; 129(3):463-76.
Score: 0.051
-
Shaldon S, Elie M, Koch KM, Dinarello CA. Interleukin-1 stimulation in the ESRD patient: potential long-term consequences. Transplant Proc. 1987 Oct; 19(5):4353-7.
Score: 0.050
-
Shaldon S, Dinarello CA. The relationship between biocompatibility and interleukin-1. Life Support Syst. 1987 Oct-Dec; 5(4):341-5.
Score: 0.050
-
Dinarello CA, Ikejima T, Warner SJ, Orencole SF, Lonnemann G, Cannon JG, Libby P. Interleukin 1 induces interleukin 1. I. Induction of circulating interleukin 1 in rabbits in vivo and in human mononuclear cells in vitro. J Immunol. 1987 Sep 15; 139(6):1902-10.
Score: 0.050
-
Lorenzo JA, Sousa SL, Alander C, Raisz LG, Dinarello CA. Comparison of the bone-resorbing activity in the supernatants from phytohemagglutinin-stimulated human peripheral blood mononuclear cells with that of cytokines through the use of an antiserum to interleukin 1. Endocrinology. 1987 Sep; 121(3):1164-70.
Score: 0.050
-
Zucali JR, Elfenbein GJ, Barth KC, Dinarello CA. Effects of human interleukin 1 and human tumor necrosis factor on human T lymphocyte colony formation. J Clin Invest. 1987 Sep; 80(3):772-7.
Score: 0.050
-
Dinarello CA, Lonnemann G, Maxwell R, Shaldon S. Ultrafiltration to reject human interleukin-1-inducing substances derived from bacterial cultures. J Clin Microbiol. 1987 Jul; 25(7):1233-8.
Score: 0.049
-
Ree HJ, Crowley JP, Dinarello CA. Anti-interleukin-1 reactive cells in Hodgkin's disease. Cancer. 1987 May 15; 59(10):1717-20.
Score: 0.049
-
Muñoz CG, Keusch GT, Dinarello CA. A new micromethod for determination of interleukin-1 production from frozen human blood mononuclear cells. J Immunol Methods. 1987 May 04; 99(1):123-7.
Score: 0.049
-
Lachman LB, Brown DC, Dinarello CA. Growth-promoting effect of recombinant interleukin 1 and tumor necrosis factor for a human astrocytoma cell line. J Immunol. 1987 May 01; 138(9):2913-6.
Score: 0.049
-
Cybulsky MI, Movat HZ, Dinarello CA. Role of interleukin-1 and tumour necrosis factor-alpha in acute inflammation. Ann Inst Pasteur Immunol. 1987 May-Jun; 138(3):505-12.
Score: 0.049
-
Mandrup-Poulsen T, Egeberg J, Nerup J, Bendtzen K, Nielsen JH, Dinarello CA. Ultrastructural studies of time-course and cellular specificity of interleukin-1 mediated islet cytotoxicity. Acta Pathol Microbiol Immunol Scand C. 1987 Apr; 95(2):55-63.
Score: 0.048
-
Auron PE, Warner SJ, Webb AC, Cannon JG, Bernheim HA, McAdam KJ, Rosenwasser LJ, LoPreste G, Mucci SF, Dinarello CA. Studies on the molecular nature of human interleukin 1. J Immunol. 1987 Mar 01; 138(5):1447-56.
Score: 0.048
-
Gauldie J, Sauder DN, McAdam KP, Dinarello CA. Purified interleukin-1 (IL-1) from human monocytes stimulates acute-phase protein synthesis by rodent hepatocytes in vitro. Immunology. 1987 Feb; 60(2):203-7.
Score: 0.048
-
Schnyder J, Payne T, Dinarello CA. Human monocyte or recombinant interleukin 1's are specific for the secretion of a metalloproteinase from chondrocytes. J Immunol. 1987 Jan 15; 138(2):496-503.
Score: 0.048
-
Dinarello CA. Interleukin-1: multiple biological properties and mechanisms of action. Adv Prostaglandin Thromboxane Leukot Res. 1987; 17B:900-4.
Score: 0.047
-
Hunninghake GW, Glazier AJ, Monick MM, Dinarello CA. Interleukin-1 is a chemotactic factor for human T-lymphocytes. Am Rev Respir Dis. 1987 Jan; 135(1):66-71.
Score: 0.047
-
Del Rey A, Besedovsky H, Sorkin E, Dinarello CA. Interleukin-1 and glucocorticoid hormones integrate an immunoregulatory feedback circuit. Ann N Y Acad Sci. 1987; 496:85-90.
Score: 0.047
-
Dinarello CA, Lonnemann G, Bingel M, Koch KM, Shaldon S. Biological consequences of monocyte activation during hemodialysis. Contrib Nephrol. 1987; 59:1-9.
Score: 0.047
-
Miller LC, Dinarello CA. Biologic activities of interleukin-1 relevant to rheumatic diseases. Pathol Immunopathol Res. 1987; 6(1):22-36.
Score: 0.047
-
Lonnemann G, Bingel M, Koch KM, Shaldon S, Dinarello CA. Plasma interleukin-1 activity in humans undergoing hemodialysis with regenerated cellulosic membranes. Lymphokine Res. 1987; 6(2):63-70.
Score: 0.047
-
Lisi PJ, Chu CW, Koch GA, Endres S, Lonnemann G, Dinarello CA. Development and use of a radioimmunoassay for human interleukin-1 beta. Lymphokine Res. 1987; 6(3):229-44.
Score: 0.047
-
Dinarello CA. The multiple biological properties of interleukin-1 influencing immunocompetent cells. Adv Exp Med Biol. 1987; 213:103-14.
Score: 0.047
-
Pincus SH, Whitcomb EA, Dinarello CA. Interaction of IL 1 and TPA in modulation of eosinophil function. J Immunol. 1986 Dec 01; 137(11):3509-14.
Score: 0.047
-
Ghezzi P, Saccardo B, Villa P, Rossi V, Bianchi M, Dinarello CA. Role of interleukin-1 in the depression of liver drug metabolism by endotoxin. Infect Immun. 1986 Dec; 54(3):837-40.
Score: 0.047
-
Libby P, Ordovas JM, Birinyi LK, Auger KR, Dinarello CA. Inducible interleukin-1 gene expression in human vascular smooth muscle cells. J Clin Invest. 1986 Dec; 78(6):1432-8.
Score: 0.047
-
Cannon JG, Evans WJ, Hughes VA, Meredith CN, Dinarello CA. Physiological mechanisms contributing to increased interleukin-1 secretion. J Appl Physiol (1985). 1986 Nov; 61(5):1869-74.
Score: 0.047
-
Dinarello CA, Krueger JM. Induction of interleukin 1 by synthetic and naturally occurring muramyl peptides. Fed Proc. 1986 Oct; 45(11):2545-8.
Score: 0.047
-
Cannon JG, Tatro JB, Reichlin S, Dinarello CA. Alpha melanocyte stimulating hormone inhibits immunostimulatory and inflammatory actions of interleukin 1. J Immunol. 1986 Oct 01; 137(7):2232-6.
Score: 0.047
-
Dinarello CA. Multiple biological properties of recombinant human interleukin 1 (beta). Immunobiology. 1986 Sep; 172(3-5):301-15.
Score: 0.046
-
Besedovsky H, del Rey A, Sorkin E, Dinarello CA. Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones. Science. 1986 Aug 08; 233(4764):652-4.
Score: 0.046
-
Libby P, Ordovas JM, Auger KR, Robbins AH, Birinyi LK, Dinarello CA. Endotoxin and tumor necrosis factor induce interleukin-1 gene expression in adult human vascular endothelial cells. Am J Pathol. 1986 Aug; 124(2):179-85.
Score: 0.046
-
Conti P, Cifone MG, Alesse E, Reale M, Fieschi C, Dinarello CA. In vitro enhanced thromboxane B2 release by polymorphonuclear leukocytes and macrophages after treatment with human recombinant interleukin 1. Prostaglandins. 1986 Jul; 32(1):111-5.
Score: 0.046
-
Nachman RL, Hajjar KA, Silverstein RL, Dinarello CA. Interleukin 1 induces endothelial cell synthesis of plasminogen activator inhibitor. J Exp Med. 1986 Jun 01; 163(6):1595-600.
Score: 0.046
-
Dinarello CA, Cannon JG, Wolff SM, Bernheim HA, Beutler B, Cerami A, Figari IS, Palladino MA, O'Connor JV. Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1. J Exp Med. 1986 Jun 01; 163(6):1433-50.
Score: 0.046
-
Dinarello CA, Cannon JG, Mier JW, Bernheim HA, LoPreste G, Lynn DL, Love RN, Webb AC, Auron PE, Reuben RC, et al. Multiple biological activities of human recombinant interleukin 1. J Clin Invest. 1986 Jun; 77(6):1734-9.
Score: 0.046
-
Carta S, Tassi S, Semino C, Fossati G, Mascagni P, Dinarello CA, Rubartelli A. Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: role of microtubules. Blood. 2006 Sep 01; 108(5):1618-26.
Score: 0.045
-
Dinarello CA, Conti P, Mier JW. Effects of human interleukin-1 on natural killer cell activity: is fever a host defense mechanism for tumor killing? Yale J Biol Med. 1986 Mar-Apr; 59(2):97-106.
Score: 0.045
-
Dayer JM, de Rochemonteix B, Burrus B, Demczuk S, Dinarello CA. Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells. J Clin Invest. 1986 Feb; 77(2):645-8.
Score: 0.045
-
Dinarello CA. Studies on the biological properties of purified and recombinant human interleukin-1. Methods Find Exp Clin Pharmacol. 1986 Feb; 8(2):57-61.
Score: 0.045
-
Dinarello CA. Interleukin-1: amino acid sequences, multiple biological activities and comparison with tumor necrosis factor (cachectin). Year Immunol. 1986; 2:68-89.
Score: 0.044
-
Bingel M, Lonnemann G, Shaldon S, Koch KM, Dinarello CA. Human interleukin-1 production during hemodialysis. Nephron. 1986; 43(3):161-3.
Score: 0.044
-
Dinarello CA, Mier JW. Interleukins. Annu Rev Med. 1986; 37:173-8.
Score: 0.044
-
Dinarello CA. Inhibitors of histone deacetylases as anti-inflammatory drugs. Ernst Schering Res Found Workshop. 2006; (56):45-60.
Score: 0.044
-
Netea MG, Azam T, Ferwerda G, Girardin SE, Walsh M, Park JS, Abraham E, Kim JM, Yoon DY, Dinarello CA, Kim SH. IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism. Proc Natl Acad Sci U S A. 2005 Nov 08; 102(45):16309-14.
Score: 0.044
-
Portnoy J, Pan T, Dinarello CA, Shannon JM, Westcott JY, Zhang L, Mason RJ. Alveolar type II cells inhibit fibroblast proliferation: role of IL-1alpha. Am J Physiol Lung Cell Mol Physiol. 2006 Feb; 290(2):L307-16.
Score: 0.043
-
Dinarello CA. An update on human interleukin-1: from molecular biology to clinical relevance. J Clin Immunol. 1985 Sep; 5(5):287-97.
Score: 0.043
-
Lewis EC, Shapiro L, Bowers OJ, Dinarello CA. Alpha1-antitrypsin monotherapy prolongs islet allograft survival in mice. Proc Natl Acad Sci U S A. 2005 Aug 23; 102(34):12153-8.
Score: 0.043
-
Crawford GD, Wyler DJ, Dinarello CA. Parasite-monocyte interactions in human leishmaniasis: production of interleukin-1 in vitro. J Infect Dis. 1985 Aug; 152(2):315-22.
Score: 0.043
-
Fitzgerald AA, Leclercq SA, Yan A, Homik JE, Dinarello CA. Rapid responses to anakinra in patients with refractory adult-onset Still's disease. Arthritis Rheum. 2005 Jun; 52(6):1794-803.
Score: 0.042
-
Cannon JG, Dinarello CA. Increased plasma interleukin-1 activity in women after ovulation. Science. 1985 Mar 08; 227(4691):1247-9.
Score: 0.042
-
Dinarello CA, Kent EF. Chemical characterization of an interleukin-1-inducing substance derived from human mixed leukocyte reactions: IL-1-inducing substance is not gamma interferon. Yale J Biol Med. 1985 Mar-Apr; 58(2):101-13.
Score: 0.042
-
Bernheim HA, Dinarello CA. Effect of protein synthesis inhibitors on leukocytic pyrogen-induced in vitro hypothalamic prostaglandin production. Yale J Biol Med. 1985 Mar-Apr; 58(2):179-87.
Score: 0.042
-
Libby P, Wyler DJ, Janicka MW, Dinarello CA. Differential effects of human interleukin-1 on growth of human fibroblasts and vascular smooth muscle cells. Arteriosclerosis. 1985 Mar-Apr; 5(2):186-91.
Score: 0.042
-
Mier JW, Souza LM, Allegretta M, Boone T, Bernheim HA, Dinarello CA. Dissimilarities between purified human interleukin-1 and recombinant human interleukin-2 in the induction of fever, brain prostaglandin, and acute-phase protein synthesis. J Biol Response Mod. 1985 Feb; 4(1):35-45.
Score: 0.042
-
Auron PE, Webb AC, Rosenwasser LJ, Mucci SF, Rich A, Wolff SM, Dinarello CA. Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. Proc Natl Acad Sci U S A. 1984 Dec; 81(24):7907-11.
Score: 0.041
-
Dinarello CA. Interleukin-1 and the pathogenesis of the acute-phase response. N Engl J Med. 1984 Nov 29; 311(22):1413-8.
Score: 0.041
-
Ludwiczek O, Vannier E, Borggraefe I, Kaser A, Siegmund B, Dinarello CA, Tilg H. Imbalance between interleukin-1 agonists and antagonists: relationship to severity of inflammatory bowel disease. Clin Exp Immunol. 2004 Nov; 138(2):323-9.
Score: 0.041
-
Dinarello CA, O'Connor JV, LoPreste G, Swift RL. Human leukocytic pyrogen test for detection of pyrogenic material in growth hormone produced by recombinant Escherichia coli. J Clin Microbiol. 1984 Sep; 20(3):323-9.
Score: 0.040
-
Dinarello CA, Clowes GH, Gordon AH, Saravis CA, Wolff SM. Cleavage of human interleukin 1: isolation of a peptide fragment from plasma of febrile humans and activated monocytes. J Immunol. 1984 Sep; 133(3):1332-8.
Score: 0.040
-
Bendtzen K, Dinarello CA. Mechanism of action of cyclosporin A. Effect on T-cell-binding of interleukin 1 and antagonizing effect of insulin. Scand J Immunol. 1984 Jul; 20(1):43-51.
Score: 0.040
-
Goldberg AL, Baracos V, Rodemann P, Waxman L, Dinarello C. Control of protein degradation in muscle by prostaglandins, Ca2+, and leukocytic pyrogen (interleukin 1). Fed Proc. 1984 Apr; 43(5):1301-6.
Score: 0.039
-
Werman A, Werman-Venkert R, White R, Lee JK, Werman B, Krelin Y, Voronov E, Dinarello CA, Apte RN. The precursor form of IL-1alpha is an intracrine proinflammatory activator of transcription. Proc Natl Acad Sci U S A. 2004 Feb 24; 101(8):2434-9.
Score: 0.039
-
Shaldon S, Koch KM, Quellhorst E, Dinarello CA. Pathogenesis of sclerosing peritonitis in CAPD. Trans Am Soc Artif Intern Organs. 1984; 30:193-4.
Score: 0.039
-
Dinarello CA. Interleukin-1. Rev Infect Dis. 1984 Jan-Feb; 6(1):51-95.
Score: 0.039
-
Dinarello CA, Bishai I, Rosenwasser LJ, Coceani F. The influence of lipoxygenase inhibitors on the in vitro production of human leukocytic pyrogen and lymphocyte activating factor (interleukin-1). Int J Immunopharmacol. 1984; 6(1):43-50.
Score: 0.039
-
Dinarello CA. Interleukin 1 as mediator of the acute-phase response. Surv Immunol Res. 1984; 3(1):29-33.
Score: 0.039
-
Song X, Voronov E, Dvorkin T, Fima E, Cagnano E, Benharroch D, Shendler Y, Bjorkdahl O, Segal S, Dinarello CA, Apte RN. Differential effects of IL-1 alpha and IL-1 beta on tumorigenicity patterns and invasiveness. J Immunol. 2003 Dec 15; 171(12):6448-56.
Score: 0.038
-
Tengesdal IW, Dinarello CA, Marchetti C. NLRP3 and cancer: Pathogenesis and therapeutic opportunities. Pharmacol Ther. 2023 11; 251:108545.
Score: 0.038
-
Lipsky PE, Thompson PA, Rosenwasser LJ, Dinarello CA. The role of interleukin 1 in human B cell activation: inhibition of B cell proliferation and the generation of immunoglobulin-secreting cells by an antibody against human leukocytic pyrogen. J Immunol. 1983 Jun; 130(6):2708-14.
Score: 0.037
-
Voronov E, Shouval DS, Krelin Y, Cagnano E, Benharroch D, Iwakura Y, Dinarello CA, Apte RN. IL-1 is required for tumor invasiveness and angiogenesis. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2645-50.
Score: 0.036
-
Dinarello CA, Marnoy SO, Rosenwasser LJ. Role of arachidonate metabolism in the immunoregulatory function of human leukocytic pyrogen/lymphocyte-activating factor/interleukin 1. J Immunol. 1983 Feb; 130(2):890-5.
Score: 0.036
-
Stuyt RJ, Kim SH, Reznikov LL, Fantuzzi G, Novick D, Rubinstein M, Kullberg BJ, van der Meer JW, Dinarello CA, Netea MG. Regulation of Staphylococcus epidermidis-induced IFN-gamma in whole human blood: the role of endogenous IL-18, IL-12, IL-1, and TNF. Cytokine. 2003 Jan 21; 21(2):65-73.
Score: 0.036
-
Carrascal MT, Mendoza L, Valcárcel M, Salado C, Egilegor E, Tellería N, Vidal-Vanaclocha F, Dinarello CA. Interleukin-18 binding protein reduces b16 melanoma hepatic metastasis by neutralizing adhesiveness and growth factors of sinusoidal endothelium. Cancer Res. 2003 Jan 15; 63(2):491-7.
Score: 0.036
-
Bufler P, Azam T, Gamboni-Robertson F, Reznikov LL, Kumar S, Dinarello CA, Kim SH. A complex of the IL-1 homologue IL-1F7b and IL-18-binding protein reduces IL-18 activity. Proc Natl Acad Sci U S A. 2002 Oct 15; 99(21):13723-8.
Score: 0.035
-
The E, de Graaf DM, Zhai Y, Yao Q, Ao L, Fullerton DA, Dinarello CA, Meng X. Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3. Proc Natl Acad Sci U S A. 2022 09 06; 119(36):e2202577119.
Score: 0.035
-
Dinarello CA, Wolff SM. Production of fever and its effects on the host. Klin Wochenschr. 1982 Jul 15; 60(14):727-30.
Score: 0.035
-
Brunt VE, Ikoba AP, Ziemba BP, Ballak DB, Hoischen A, Dinarello CA, Ehringer MA, Seals DR. Circulating interleukin-37 declines with aging in healthy humans: relations to healthspan indicators and IL37 gene SNPs. Geroscience. 2023 02; 45(1):65-84.
Score: 0.034
-
Netea MG, Stuyt RJ, Kim SH, Van der Meer JW, Kullberg BJ, Dinarello CA. The role of endogenous interleukin (IL)-18, IL-12, IL-1beta, and tumor necrosis factor-alpha in the production of interferon-gamma induced by Candida albicans in human whole-blood cultures. J Infect Dis. 2002 Apr 01; 185(7):963-70.
Score: 0.034
-
Dinarello CA, Bendtzen K, Wolff SM. Studies on the active site of human leukocytic pyrogen. Inflammation. 1982 Mar; 6(1):63-78.
Score: 0.034
-
Gatti S, Beck J, Fantuzzi G, Bartfai T, Dinarello CA. Effect of interleukin-18 on mouse core body temperature. Am J Physiol Regul Integr Comp Physiol. 2002 Mar; 282(3):R702-9.
Score: 0.034
-
Schultz MJ, Rijneveld AW, Florquin S, Edwards CK, Dinarello CA, van der Poll T. Role of interleukin-1 in the pulmonary immune response during Pseudomonas aeruginosa pneumonia. Am J Physiol Lung Cell Mol Physiol. 2002 Feb; 282(2):L285-90.
Score: 0.034
-
Dinarello CA, Dempsey RA, Mier JW, Rosenwasser LJ, Parkinson DR. Fever, interleukin-1 and host defense against malignancy. Lymphokine Res. 1982; 1(3):59-67.
Score: 0.034
-
Teufel LU, Arts RJW, Netea MG, Dinarello CA, Joosten LAB. IL-1 family cytokines as drivers and inhibitors of trained immunity. Cytokine. 2022 02; 150:155773.
Score: 0.033
-
Dinarello CA. Novel targets for interleukin 18 binding protein. Ann Rheum Dis. 2001 Nov; 60 Suppl 3:iii18-24.
Score: 0.033
-
Siegmund B, Lehr HA, Fantuzzi G, Dinarello CA. IL-1 beta -converting enzyme (caspase-1) in intestinal inflammation. Proc Natl Acad Sci U S A. 2001 Nov 06; 98(23):13249-54.
Score: 0.033
-
Dinarello CA, Shparber M, Kent EF, Wolff SM. Production of leukocytic pyrogen from phagocytes of neonates. J Infect Dis. 1981 Oct; 144(4):337-43.
Score: 0.033
-
Dinarello CA, Bernheim HA. Ability of human leukocytic pyrogen to stimulate brain prostaglandin synthesis in vitro. J Neurochem. 1981 Sep; 37(3):702-8.
Score: 0.033
-
Javan H, Li L, Schaaf CL, Lee YS, Salama ME, Dinarello CA, Selzman CH. Interleukin-1 Receptor Antagonism Abrogates Acute Pressure Overload-Induced Murine Heart Failure. Ann Thorac Surg. 2022 07; 114(1):98-107.
Score: 0.033
-
de Graaf DM, Teufel LU, van de Veerdonk FL, Joosten LAB, Netea MG, Dinarello CA, Arts RJW. IL-38 prevents induction of trained immunity by inhibition of mTOR signaling. J Leukoc Biol. 2021 11; 110(5):907-915.
Score: 0.032
-
Kim SH, Reznikov LL, Stuyt RJ, Selzman CH, Fantuzzi G, Hoshino T, Young HA, Dinarello CA. Functional reconstitution and regulation of IL-18 activity by the IL-18R beta chain. J Immunol. 2001 Jan 01; 166(1):148-54.
Score: 0.031
-
O'Neill LA, Dinarello CA. The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense. Immunol Today. 2000 May; 21(5):206-9.
Score: 0.030
-
Kristiansen OP, Pociot F, Johannesen J, Bergholdt R, Dinarello CA, Nerup J, Mandrup-Poulsen T. Linkage disequilibrium testing of four interleukin-1 gene-cluster polymorphisms in Danish multiplex families with insulin-dependent diabetes mellitus. Cytokine. 2000 Feb; 12(2):171-5.
Score: 0.029
-
Donath MY, Dinarello CA, Mandrup-Poulsen T. Targeting innate immune mediators in type 1 and type 2 diabetes. Nat Rev Immunol. 2019 12; 19(12):734-746.
Score: 0.029
-
Cain BS, Meldrum DR, Dinarello CA, Meng X, Joo KS, Banerjee A, Harken AH. Tumor necrosis factor-alpha and interleukin-1beta synergistically depress human myocardial function. Crit Care Med. 1999 Jul; 27(7):1309-18.
Score: 0.028
-
Netea MG, Kullberg BJ, Boerman OC, Verschueren I, Dinarello CA, Van der Meer JW. Soluble murine IL-1 receptor type I induces release of constitutive IL-1 alpha. J Immunol. 1999 Apr 15; 162(8):4876-81.
Score: 0.028
-
Dinarello CA. Cytokines as endogenous pyrogens. J Infect Dis. 1999 Mar; 179 Suppl 2:S294-304.
Score: 0.028
-
Dinarello CA, Gatti S, Bartfai T. Fever: links with an ancient receptor. Curr Biol. 1999 Feb 25; 9(4):R147-50.
Score: 0.028
-
Mercurio L, Morelli M, Scarponi C, Eisenmesser EZ, Doti N, Pagnanelli G, Gubinelli E, Mazzanti C, Cavani A, Ruvo M, Dinarello CA, Albanesi C, Madonna S. IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment. Cell Death Dis. 2018 10 30; 9(11):1104.
Score: 0.027
-
Fraenkel L, Roubenoff R, LaValley M, McAlindon T, Chaisson C, Evans S, Harris T, Dinarello CA, Felson DT. The association of peripheral monocyte derived interleukin 1beta (IL-1beta), IL-1 receptor antagonist, and tumor necrosis factor-alpha with osteoarthritis in the elderly. J Rheumatol. 1998 Sep; 25(9):1820-6.
Score: 0.027
-
Shapiro L, Heidenreich KA, Meintzer MK, Dinarello CA. Role of p38 mitogen-activated protein kinase in HIV type 1 production in vitro. Proc Natl Acad Sci U S A. 1998 Jun 23; 95(13):7422-6.
Score: 0.026
-
Larsen CM, Wadt KA, Juhl LF, Andersen HU, Karlsen AE, Su MS, Seedorf K, Shapiro L, Dinarello CA, Mandrup-Poulsen T. Interleukin-1beta-induced rat pancreatic islet nitric oxide synthesis requires both the p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases. J Biol Chem. 1998 Jun 12; 273(24):15294-300.
Score: 0.026
-
Faggioni R, Fantuzzi G, Fuller J, Dinarello CA, Feingold KR, Grunfeld C. IL-1 beta mediates leptin induction during inflammation. Am J Physiol. 1998 01; 274(1):R204-8.
Score: 0.025
-
Roubenoff R, Harris TB, Abad LW, Wilson PW, Dallal GE, Dinarello CA. Monocyte cytokine production in an elderly population: effect of age and inflammation. J Gerontol A Biol Sci Med Sci. 1998 Jan; 53(1):M20-6.
Score: 0.025
-
Dinarello CA. Proinflammatory and anti-inflammatory cytokines as mediators in the pathogenesis of septic shock. Chest. 1997 Dec; 112(6 Suppl):321S-329S.
Score: 0.025
-
Mühl H, Dinarello CA. Macrophage inflammatory protein-1 alpha production in lipopolysaccharide-stimulated human adherent blood mononuclear cells is inhibited by the nitric oxide synthase inhibitor N(G)-monomethyl-L-arginine. J Immunol. 1997 Nov 15; 159(10):5063-9.
Score: 0.025
-
van Deuren M, van der Ven-Jongekrijg J, Vannier E, van Dalen R, Pesman G, Bartelink AK, Dinarello CA, van der Meer JW. The pattern of interleukin-1beta (IL-1beta) and its modulating agents IL-1 receptor antagonist and IL-1 soluble receptor type II in acute meningococcal infections. Blood. 1997 Aug 01; 90(3):1101-8.
Score: 0.025
-
Alheim K, Chai Z, Fantuzzi G, Hasanvan H, Malinowsky D, Di Santo E, Ghezzi P, Dinarello CA, Bartfai T. Hyperresponsive febrile reactions to interleukin (IL) 1alpha and IL-1beta, and altered brain cytokine mRNA and serum cytokine levels, in IL-1beta-deficient mice. Proc Natl Acad Sci U S A. 1997 Mar 18; 94(6):2681-6.
Score: 0.024
-
Fantuzzi G, Ku G, Harding MW, Livingston DJ, Sipe JD, Kuida K, Flavell RA, Dinarello CA. Response to local inflammation of IL-1 beta-converting enzyme- deficient mice. J Immunol. 1997 Feb 15; 158(4):1818-24.
Score: 0.024
-
Aiura K, Clark BD, Dinarello CA, Margolis NH, Kaplanski G, Burke JF, Tompkins RG, Gelfand JA. Interaction with autologous platelets multiplies interleukin-1 and tumor necrosis factor production in mononuclear cells. J Infect Dis. 1997 Jan; 175(1):123-9.
Score: 0.024
-
Torcia M, Lucibello M, Vannier E, Fabiani S, Miliani A, Guidi G, Spada O, Dower SK, Sims JE, Shaw AR, Dinarello CA, Garaci E, Cozzolino F. Modulation of osteoclast-activating factor activity of multiple myeloma bone marrow cells by different interleukin-1 inhibitors. Exp Hematol. 1996 Jul; 24(8):868-74.
Score: 0.023
-
Takabayashi T, Vannier E, Clark BD, Margolis NH, Dinarello CA, Burke JF, Gelfand JA. A new biologic role for C3a and C3a desArg: regulation of TNF-alpha and IL-1 beta synthesis. J Immunol. 1996 May 01; 156(9):3455-60.
Score: 0.023
-
Vannier E, de Waal Malefyt R, Salazar-Montes A, de Vries JE, Dinarello CA. Interleukin-13 (IL-13) induces IL-1 receptor antagonist gene expression and protein synthesis in peripheral blood mononuclear cells: inhibition by an IL-4 mutant protein. Blood. 1996 Apr 15; 87(8):3307-15.
Score: 0.023
-
Dinarello CA. Cytokines as mediators in the pathogenesis of septic shock. Curr Top Microbiol Immunol. 1996; 216:133-65.
Score: 0.022
-
Pomianek MJ, Colton CK, Dinarello CA, Miller LC. Synthesis of tumor necrosis factor alpha and interleukin-1 receptor antagonist, but not interleukin-1, by human mononuclear cells is enhanced by exposure of whole blood to shear stress. ASAIO J. 1996 Jan-Feb; 42(1):52-9.
Score: 0.022
-
Dinarello CA, Roubenoff R. George Clowes' classic paper and the search for "muscle proteolysis factor". Nutrition. 1996 Jan; 12(1):67-8.
Score: 0.022
-
Shapiro L, Dinarello CA. Osmotic regulation of cytokine synthesis in vitro. Proc Natl Acad Sci U S A. 1995 Dec 19; 92(26):12230-4.
Score: 0.022
-
Kaplanski G, Teysseire N, Farnarier C, Kaplanski S, Lissitzky JC, Durand JM, Soubeyrand J, Dinarello CA, Bongrand P. IL-6 and IL-8 production from cultured human endothelial cells stimulated by infection with Rickettsia conorii via a cell-associated IL-1 alpha-dependent pathway. J Clin Invest. 1995 Dec; 96(6):2839-44.
Score: 0.022
-
Beasley D, McGuiggin ME, Dinarello CA. Human vascular smooth muscle cells produce an intracellular form of interleukin-1 receptor antagonist. Am J Physiol. 1995 Oct; 269(4 Pt 1):C961-8.
Score: 0.022
-
Granowitz EV, Saget BM, Wang MZ, Dinarello CA, Skolnik PR. Interleukin 1 induces HIV-1 expression in chronically infected U1 cells: blockade by interleukin 1 receptor antagonist and tumor necrosis factor binding protein type 1. Mol Med. 1995 Sep; 1(6):667-77.
Score: 0.022
-
Miller LC, Sharma A, McKusick AF, Tassoni JP, Dinarello CA, Kaplan MM. Synthesis of interleukin-1 beta in primary biliary cirrhosis: relationship to treatment with methotrexate or colchicine and disease progression. Hepatology. 1995 Aug; 22(2):518-24.
Score: 0.021
-
Schindler R, Dinarello CA, Koch KM. Angiotensin-converting-enzyme inhibitors suppress synthesis of tumour necrosis factor and interleukin 1 by human peripheral blood mononuclear cells. Cytokine. 1995 Aug; 7(6):526-33.
Score: 0.021
-
Mileno MD, Margolis NH, Clark BD, Dinarello CA, Burke JF, Gelfand JA. Coagulation of whole blood stimulates interleukin-1 beta gene expression. J Infect Dis. 1995 Jul; 172(1):308-11.
Score: 0.021
-
Stosic-Grujicic S, Basara N, Milenkovic P, Dinarello CA. Modulation of acute myeloblastic leukemia (AML) cell proliferation and blast colony formation by antisense oligomer for IL-1 beta converting enzyme (ICE) and IL-1 receptor antagonist (IL-1ra). J Chemother. 1995 Feb; 7(1):67-70.
Score: 0.021
-
Fantuzzi G, Benigni F, Sironi M, Conni M, Carelli M, Cantoni L, Shapiro L, Dinarello CA, Sipe JD, Ghezzi P. Ciliary neurotrophic factor (CNTF) induces serum amyloid A, hypoglycaemia and anorexia, and potentiates IL-1 induced corticosterone and IL-6 production in mice. Cytokine. 1995 Feb; 7(2):150-6.
Score: 0.021
-
Vogels MT, Mensink EJ, Ye K, Boerman OC, Verschueren CM, Dinarello CA, van der Meer JW. Differential gene expression for IL-1 receptor antagonist, IL-1, and TNF receptors and IL-1 and TNF synthesis may explain IL-1-induced resistance to infection. J Immunol. 1994 Dec 15; 153(12):5772-80.
Score: 0.021
-
Lynch EA, Dinarello CA, Cannon JG. Gender differences in IL-1 alpha, IL-1 beta, and IL-1 receptor antagonist secretion from mononuclear cells and urinary excretion. J Immunol. 1994 Jul 01; 153(1):300-6.
Score: 0.020
-
Roubenoff R, Roubenoff RA, Cannon JG, Kehayias JJ, Zhuang H, Dawson-Hughes B, Dinarello CA, Rosenberg IH. Rheumatoid cachexia: cytokine-driven hypermetabolism accompanying reduced body cell mass in chronic inflammation. J Clin Invest. 1994 Jun; 93(6):2379-86.
Score: 0.020
-
Proud D, Gwaltney JM, Hendley JO, Dinarello CA, Gillis S, Schleimer RP. Increased levels of interleukin-1 are detected in nasal secretions of volunteers during experimental rhinovirus colds. J Infect Dis. 1994 May; 169(5):1007-13.
Score: 0.020
-
Mester M, Carter EA, Tompkins RG, Gelfand JA, Dinarello CA, Burke JF, Clark BD. Thermal injury induces very early production of interleukin-1 alpha in the rat by mechanisms other than endotoxemia. Surgery. 1994 May; 115(5):588-96.
Score: 0.020
-
Tilg H, Shapiro L, Vannier E, Poutsiaka DD, Trehu E, Atkins MB, Dinarello CA, Mier JW. Induction of circulating antagonists to IL-1 and TNF by IL-2 administration and their effects on IL-2 induced cytokine production in vitro. J Immunol. 1994 Mar 15; 152(6):3189-98.
Score: 0.020
-
Tilg H, Trehu E, Shapiro L, Pape D, Atkins MB, Dinarello CA, Mier JW. Induction of circulating soluble tumour necrosis factor receptor and interleukin 1 receptor antagonist following interleukin 1 alpha infusion in humans. Cytokine. 1994 Mar; 6(2):215-9.
Score: 0.019
-
Manetti R, Barak V, Piccinni MP, Sampognaro S, Parronchi P, Maggi E, Dinarello CA, Romagnani S. Interleukin-1 favours the in vitro development of type 2 T helper (Th2) human T-cell clones. Res Immunol. 1994 Feb; 145(2):93-100.
Score: 0.019
-
Endres S, Meydani SN, Ghorbani R, Schindler R, Dinarello CA. Dietary supplementation with n-3 fatty acids suppresses interleukin-2 production and mononuclear cell proliferation. J Leukoc Biol. 1993 Dec; 54(6):599-603.
Score: 0.019
-
Tilg H, Vannier E, Vachino G, Dinarello CA, Mier JW. Antiinflammatory properties of hepatic acute phase proteins: preferential induction of interleukin 1 (IL-1) receptor antagonist over IL-1 beta synthesis by human peripheral blood mononuclear cells. J Exp Med. 1993 Nov 01; 178(5):1629-36.
Score: 0.019
-
Shapiro L, Zhang XX, Rupp RG, Wolff SM, Dinarello CA. Ciliary neurotrophic factor is an endogenous pyrogen. Proc Natl Acad Sci U S A. 1993 Sep 15; 90(18):8614-8.
Score: 0.019
-
Mancilla-Ramírez J, Ramírez-Herrera M, Portillo-Gómez L, Gaitán-Meza J, Dinarello CA. [Antagonists in neonatal sepsis]. Bol Med Hosp Infant Mex. 1993 Sep; 50(9):691-3.
Score: 0.019
-
Tilg H, Pape D, Trehu E, Shapiro L, Atkins MB, Dinarello CA, Mier JW. A method for the detection of erythrocyte-bound interleukin-8 in humans during interleukin-1 immunotherapy. J Immunol Methods. 1993 Aug 09; 163(2):253-8.
Score: 0.019
-
Granowitz EV, Porat R, Mier JW, Orencole SF, Kaplanski G, Lynch EA, Ye K, Vannier E, Wolff SM, Dinarello CA. Intravenous endotoxin suppresses the cytokine response of peripheral blood mononuclear cells of healthy humans. J Immunol. 1993 Aug 01; 151(3):1637-45.
Score: 0.019
-
Zumsteg U, Reimers JI, Pociot F, Mørch L, Helqvist S, Brendel M, Alejandro R, Mandrup-Poulsen T, Dinarello CA, Nerup J. Differential interleukin-1 receptor antagonism on pancreatic beta and alpha cells. Studies in rodent and human islets and in normal rats. Diabetologia. 1993 Aug; 36(8):759-66.
Score: 0.019
-
Bersudsky M, Luski L, Fishman D, White RM, Ziv-Sokolovskaya N, Dotan S, Rider P, Kaplanov I, Aychek T, Dinarello CA, Apte RN, Voronov E. Non-redundant properties of IL-1a and IL-1ß during acute colon inflammation in mice. Gut. 2014 Apr; 63(4):598-609.
Score: 0.019
-
Mester M, Tompkins RG, Gelfand JA, Dinarello CA, Burke JF, Clark BD. Intestinal production of interleukin-1 alpha during endotoxemia in the mouse. J Surg Res. 1993 Jun; 54(6):584-91.
Score: 0.018
-
Tilg H, Mier JW, Vogel W, Aulitzky WE, Wiedermann CJ, Vannier E, Huber C, Dinarello CA. Induction of circulating IL-1 receptor antagonist by IFN treatment. J Immunol. 1993 May 15; 150(10):4687-92.
Score: 0.018
-
Mandrup-Poulsen T, Zumsteg U, Reimers J, Pociot F, Mørch L, Helqvist S, Dinarello CA, Nerup J. Involvement of interleukin 1 and interleukin 1 antagonist in pancreatic beta-cell destruction in insulin-dependent diabetes mellitus. Cytokine. 1993 May; 5(3):185-91.
Score: 0.018
-
Romero LI, Schettini G, Lechan RM, Dinarello CA, Reichlin S. Bacterial lipopolysaccharide induction of IL-6 in rat telencephalic cells is mediated in part by IL-1. Neuroendocrinology. 1993 May; 57(5):892-7.
Score: 0.018
-
Dinarello CA, Gelfand JA, Wolff SM. Anticytokine strategies in the treatment of the systemic inflammatory response syndrome. JAMA. 1993 Apr 14; 269(14):1829-35.
Score: 0.018
-
Mancilla J, García P, Dinarello CA. The interleukin-1 receptor antagonist can either reduce or enhance the lethality of Klebsiella pneumoniae sepsis in newborn rats. Infect Immun. 1993 Mar; 61(3):926-32.
Score: 0.018
-
Schindler R, Linnenweber S, Schulze M, Oppermann M, Dinarello CA, Shaldon S, Koch KM. Gene expression of interleukin-1 beta during hemodialysis. Kidney Int. 1993 Mar; 43(3):712-21.
Score: 0.018
-
Miller LC, Lynch EA, Isa S, Logan JW, Dinarello CA, Steere AC. Balance of synovial fluid IL-1 beta and IL-1 receptor antagonist and recovery from Lyme arthritis. Lancet. 1993 Jan 16; 341(8838):146-8.
Score: 0.018
-
Kaplan E, Dinarello CA, Wakabayashi G, Burke JF, Connolly RS, Gelfand JA. Interleukin-1 pretreatment protects against endotoxin-induced hypotension in rabbits: association with decreased tumor necrosis factor levels. J Infect Dis. 1993 Jan; 167(1):244-7.
Score: 0.018
-
Nerad JL, Griffiths JK, Van der Meer JW, Endres S, Poutsiaka DD, Keusch GT, Bennish M, Salam MA, Dinarello CA, Cannon JG. Interleukin-1 beta (IL-1 beta), IL-1 receptor antagonist, and TNF alpha production in whole blood. J Leukoc Biol. 1992 Dec; 52(6):687-92.
Score: 0.018
-
Pereira BJ, Poutsiaka DD, King AJ, Strom JA, Narayan G, Levey AS, Dinarello CA. In vitro production of interleukin-1 receptor antagonist in chronic renal failure, CAPD and HD. Kidney Int. 1992 Dec; 42(6):1419-24.
Score: 0.018
-
Andersson J, Björk L, Dinarello CA, Towbin H, Andersson U. Lipopolysaccharide induces human interleukin-1 receptor antagonist and interleukin-1 production in the same cell. Eur J Immunol. 1992 Oct; 22(10):2617-23.
Score: 0.018
-
Memon RA, Feingold KR, Moser AH, Doerrler W, Adi S, Dinarello CA, Grunfeld C. Differential effects of interleukin-1 and tumor necrosis factor on ketogenesis. Am J Physiol. 1992 Aug; 263(2 Pt 1):E301-9.
Score: 0.017
-
Ho JL, Badaró R, Schwartz A, Dinarello CA, Gelfand JA, Sobel J, Barral A, Netto MB, Carvalho EM, Reed SG, et al. Diminished in vitro production of interleukin-1 and tumor necrosis factor-alpha during acute visceral leishmaniasis and recovery after therapy. J Infect Dis. 1992 Jun; 165(6):1094-102.
Score: 0.017
-
Granowitz EV, Vannier E, Poutsiaka DD, Dinarello CA. Effect of interleukin-1 (IL-1) blockade on cytokine synthesis: II. IL-1 receptor antagonist inhibits lipopolysaccharide-induced cytokine synthesis by human monocytes. Blood. 1992 May 01; 79(9):2364-9.
Score: 0.017
-
Dinarello CA. Cytokines: agents provocateurs in hemodialysis? Kidney Int. 1992 Mar; 41(3):683-94.
Score: 0.017
-
Feingold KR, Doerrler W, Dinarello CA, Fiers W, Grunfeld C. Stimulation of lipolysis in cultured fat cells by tumor necrosis factor, interleukin-1, and the interferons is blocked by inhibition of prostaglandin synthesis. Endocrinology. 1992 Jan; 130(1):10-6.
Score: 0.017
-
Rambaldi A, Torcia M, Bettoni S, Vannier E, Barbui T, Shaw AR, Dinarello CA, Cozzolino F. Modulation of cell proliferation and cytokine production in acute myeloblastic leukemia by interleukin-1 receptor antagonist and lack of its expression by leukemic cells. Blood. 1991 Dec 15; 78(12):3248-53.
Score: 0.017
-
Dinarello CA, Cannon JG, Mancilla J, Bishai I, Lees J, Coceani F. Interleukin-6 as an endogenous pyrogen: induction of prostaglandin E2 in brain but not in peripheral blood mononuclear cells. Brain Res. 1991 Oct 25; 562(2):199-206.
Score: 0.017
-
Grunfeld C, Dinarello CA, Feingold KR. Tumor necrosis factor-alpha, interleukin-1, and interferon alpha stimulate triglyceride synthesis in HepG2 cells. Metabolism. 1991 Sep; 40(9):894-8.
Score: 0.016
-
Cohan VL, Scott AL, Dinarello CA, Prendergast RA. Interleukin-1 is a mucus secretagogue. Cell Immunol. 1991 Sep; 136(2):425-34.
Score: 0.016
-
Ghezzi P, Dinarello CA, Bianchi M, Rosandich ME, Repine JE, White CW. Hypoxia increases production of interleukin-1 and tumor necrosis factor by human mononuclear cells. Cytokine. 1991 May; 3(3):189-94.
Score: 0.016
-
Feingold KR, Soued M, Adi S, Staprans I, Neese R, Shigenaga J, Doerrler W, Moser A, Dinarello CA, Grunfeld C. Effect of interleukin-1 on lipid metabolism in the rat. Similarities to and differences from tumor necrosis factor. Arterioscler Thromb. 1991 May-Jun; 11(3):495-500.
Score: 0.016
-
Dustin ML, Rothlein R, Bhan AK, Dinarello CA, Springer TA. Induction by IL 1 and interferon-?: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J. Immunol. 1986. 137: 245-254. J Immunol. 2011 May 01; 186(9):5024-33.
Score: 0.016
-
Conti P, Reale M, Barbacane RC, Panara MR, Bongrazio M, Dempsey RA, Dinarello CA. Reduced mitogen stimulation of DNA synthesis in human lymphocytes by a human recombinant interleukin-1 receptor antagonist. Immunol Lett. 1991 Apr; 28(1):19-25.
Score: 0.016
-
Clinton SK, Fleet JC, Loppnow H, Salomon RN, Clark BD, Cannon JG, Shaw AR, Dinarello CA, Libby P. Interleukin-1 gene expression in rabbit vascular tissue in vivo. Am J Pathol. 1991 Apr; 138(4):1005-14.
Score: 0.016
-
Kamari Y, Shaish A, Vax E, Shemesh S, Kandel-Kfir M, Arbel Y, Olteanu S, Barshack I, Dotan S, Voronov E, Dinarello CA, Apte RN, Harats D. Lack of interleukin-1a or interleukin-1ß inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice. J Hepatol. 2011 Nov; 55(5):1086-94.
Score: 0.016
-
Miller LG, Galpern WR, Dunlap K, Dinarello CA, Turner TJ. Interleukin-1 augments gamma-aminobutyric acidA receptor function in brain. Mol Pharmacol. 1991 Feb; 39(2):105-8.
Score: 0.016
-
Endres S, Fülle HJ, Sinha B, Stoll D, Dinarello CA, Gerzer R, Weber PC. Cyclic nucleotides differentially regulate the synthesis of tumour necrosis factor-alpha and interleukin-1 beta by human mononuclear cells. Immunology. 1991 Jan; 72(1):56-60.
Score: 0.016
-
Morin M, Schindler R, Wakabayashi G, Daumy G, Dinarello CA, Gelfand JA. Picogram concentrations of endotoxin stimulate synthesis of IL-1 beta and TNF alpha by human peripheral blood mononuclear cells exposed to recombinant human C5a. Eur Cytokine Netw. 1991 Jan-Feb; 2(1):27-30.
Score: 0.016
-
Endres S, Meydani SN, Dinarello CA. Effects of omega 3 fatty acid supplements on ex vivo synthesis of cytokines in human volunteers. Comparison with oral aspirin and ibuprofen. World Rev Nutr Diet. 1991; 66:401-6.
Score: 0.016
-
Bochner BS, Charlesworth EN, Lichtenstein LM, Derse CP, Gillis S, Dinarello CA, Schleimer RP. Interleukin-1 is released at sites of human cutaneous allergic reactions. J Allergy Clin Immunol. 1990 Dec; 86(6 Pt 1):830-9.
Score: 0.016
-
Bianchi M, Mantovani A, Erroi A, Dinarello CA, Ghezzi P. Ambroxol inhibits interleukin 1 and tumor necrosis factor production in human mononuclear cells. Agents Actions. 1990 Nov; 31(3-4):275-9.
Score: 0.015
-
Numerof RP, Kotik AN, Dinarello CA, Mier JW. Pro-interleukin-1 beta production by a subpopulation of human T cells, but not NK cells, in response to interleukin-2. Cell Immunol. 1990 Oct 01; 130(1):118-28.
Score: 0.015
-
Galy AH, Dinarello CA, Kupper TS, Kameda A, Hadden JW. Effects of cytokines on human thymic epithelial cells in culture. II. Recombinant IL 1 stimulates thymic epithelial cells to produce IL6 and GM-CSF. Cell Immunol. 1990 Aug; 129(1):161-75.
Score: 0.015
-
Grunfeld C, Soued M, Adi S, Moser AH, Dinarello CA, Feingold KR. Evidence for two classes of cytokines that stimulate hepatic lipogenesis: relationships among tumor necrosis factor, interleukin-1 and interferon-alpha. Endocrinology. 1990 Jul; 127(1):46-54.
Score: 0.015
-
Kandel RA, Petelycky M, Dinarello CA, Minden M, Pritzker KP, Cruz TF. Comparison of the effect of interleukin 6 and interleukin 1 on collagenase and proteoglycan production by chondrocytes. J Rheumatol. 1990 Jul; 17(7):953-7.
Score: 0.015
-
Koenig JI, Snow K, Clark BD, Toni R, Cannon JG, Shaw AR, Dinarello CA, Reichlin S, Lee SL, Lechan RM. Intrinsic pituitary interleukin-1 beta is induced by bacterial lipopolysaccharide. Endocrinology. 1990 Jun; 126(6):3053-8.
Score: 0.015
-
Molina JM, Scadden DT, Amirault C, Woon A, Vannier E, Dinarello CA, Groopman JE. Human immunodeficiency virus does not induce interleukin-1, interleukin-6, or tumor necrosis factor in mononuclear cells. J Virol. 1990 Jun; 64(6):2901-6.
Score: 0.015
-
Lechan RM, Toni R, Clark BD, Cannon JG, Shaw AR, Dinarello CA, Reichlin S. Immunoreactive interleukin-1 beta localization in the rat forebrain. Brain Res. 1990 Apr 23; 514(1):135-40.
Score: 0.015
-
Abbate A, Kontos MC, Grizzard JD, Biondi-Zoccai GG, Van Tassell BW, Robati R, Roach LM, Arena RA, Roberts CS, Varma A, Gelwix CC, Salloum FN, Hastillo A, Dinarello CA, Vetrovec GW. Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study). Am J Cardiol. 2010 May 15; 105(10):1371-1377.e1.
Score: 0.015
-
Schindler R, Dinarello CA. Ultrafiltration to remove endotoxins and other cytokine-inducing materials from tissue culture media and parenteral fluids. Biotechniques. 1990 Apr; 8(4):408-13.
Score: 0.015
-
Wilson CS, Ellner JJ, Dinarello CA, Keusch GT, el Kholy A. Dissociation of immunoregulatory function of blood monocytes from maturational state and expression of interleukin-1 in humans chronically infected with Schistosoma mansoni. Am J Trop Med Hyg. 1990 Mar; 42(3):234-42.
Score: 0.015
-
Salem P, Deryckx S, Dulioust A, Vivier E, Denizot Y, Damais C, Dinarello CA, Thomas Y. Immunoregulatory functions of paf-acether. IV. Enhancement of IL-1 production by muramyl dipeptide-stimulated monocytes. J Immunol. 1990 Feb 15; 144(4):1338-44.
Score: 0.015
-
Cominelli F, Nast CC, Llerena R, Dinarello CA, Zipser RD. Interleukin 1 suppresses inflammation in rabbit colitis. Mediation by endogenous prostaglandins. J Clin Invest. 1990 Feb; 85(2):582-6.
Score: 0.015
-
Park MM, Hornback NB, Endres S, Dinarello CA. The effect of whole body hyperthermia on the immune cell activity of cancer patients. Lymphokine Res. 1990; 9(2):213-23.
Score: 0.015
-
Wogensen LD, Kolb-Bachofen V, Christensen P, Dinarello CA, Mandrup-Poulsen T, Martin S, Nerup J. Functional and morphological effects of interleukin-1 beta on the perfused rat pancreas. Diabetologia. 1990 Jan; 33(1):15-23.
Score: 0.015
-
Cominelli F, Nast CC, Dinarello CA, Gentilini P, Zipser RD. Regulation of eicosanoid production in rabbit colon by interleukin-1. Gastroenterology. 1989 Dec; 97(6):1400-5.
Score: 0.015
-
Molina JM, Scadden DT, Byrn R, Dinarello CA, Groopman JE. Production of tumor necrosis factor alpha and interleukin 1 beta by monocytic cells infected with human immunodeficiency virus. J Clin Invest. 1989 Sep; 84(3):733-7.
Score: 0.014
-
Cannon JG, Fielding RA, Fiatarone MA, Orencole SF, Dinarello CA, Evans WJ. Increased interleukin 1 beta in human skeletal muscle after exercise. Am J Physiol. 1989 Aug; 257(2 Pt 2):R451-5.
Score: 0.014
-
Andrews HJ, Bunning RA, Dinarello CA, Russell RG. Modulation of human chondrocyte metabolism by recombinant human interferon gamma: in-vitro effects on basal and IL-1-stimulated proteinase production, cartilage degradation and DNA synthesis. Biochim Biophys Acta. 1989 Jul 11; 1012(2):128-34.
Score: 0.014
-
Tsoukas CD, Watry D, Escobar SS, Provvedini DM, Dinarello CA, Hustmyer FG, Manolagas SC. Inhibition of interleukin-1 production by 1,25-dihydroxyvitamin D3. J Clin Endocrinol Metab. 1989 Jul; 69(1):127-33.
Score: 0.014
-
Gottlieb RA, Lennarz WJ, Knowles RD, Cianciolo GJ, Dinarello CA, Lachman LB, Kleinerman ES. Synthetic peptide corresponding to a conserved domain of the retroviral protein p15E blocks IL-1-mediated signal transduction. J Immunol. 1989 Jun 15; 142(12):4321-8.
Score: 0.014
-
Drapkin MS, Wisch JS, Gelfand JA, Cannon JG, Dinarello CA. Plasmapheresis for fulminant meningococcemia. Pediatr Infect Dis J. 1989 Jun; 8(6):399-400.
Score: 0.014
-
Endres S, van der Meer JW, Dinarello CA. [Cytokines in the pathogenesis of fever]. Internist (Berl). 1989 Jun; 30(6):358-61.
Score: 0.014
-
Whitcomb EA, Dinarello CA, Pincus SH. Differential effects of interleukin-1 alpha and interleukin-1 beta on human peripheral blood eosinophils. Blood. 1989 May 15; 73(7):1904-8.
Score: 0.014
-
Loppnow H, Brade H, Dürrbaum I, Dinarello CA, Kusumoto S, Rietschel ET, Flad HD. IL-1 induction-capacity of defined lipopolysaccharide partial structures. J Immunol. 1989 May 01; 142(9):3229-38.
Score: 0.014
-
Flores EA, Bistrian BR, Pomposelli JJ, Dinarello CA, Blackburn GL, Istfan NW. Infusion of tumor necrosis factor/cachectin promotes muscle catabolism in the rat. A synergistic effect with interleukin 1. J Clin Invest. 1989 May; 83(5):1614-22.
Score: 0.014
-
Cannon JG, Clark BD, Wingfield P, Schmeissner U, Losberger C, Dinarello CA, Shaw AR. Rabbit IL-1. Cloning, expression, biologic properties, and transcription during endotoxemia. J Immunol. 1989 Apr 01; 142(7):2299-306.
Score: 0.014
-
Flores EA, Drabik M, Gauldie J, Blackburn GL, Dinarello CA, Bistrian BR. Leukocyte endogenous mediator fails to alter protein dynamics in a model of liver dysfunction. J Lab Clin Med. 1989 Feb; 113(2):211-20.
Score: 0.014
-
Gothelf Y, Dinarello CA, Yamin M, Sharon N, Milner Y, Gazit E. IL-1 production by T6 (CD1a) positive cord blood mononuclear cells (Langerhan's cell precursors?). Lymphokine Res. 1989; 8(4):373-82.
Score: 0.014
-
Scarborough DE, Lee SL, Dinarello CA, Reichlin S. Interleukin-1 beta stimulates somatostatin biosynthesis in primary cultures of fetal rat brain. Endocrinology. 1989 Jan; 124(1):549-51.
Score: 0.014
-
Cady AB, Riveau G, Chedid L, Dinarello CA, Johannsen L, Krueger JM. Interleukin-1-induced sleep and febrile responses differentially altered by a muramyl dipeptide derivative. Int J Immunopharmacol. 1989; 11(8):887-93.
Score: 0.014
-
Kaplan E, Dinarello CA, Gelfand JA. Interleukin-1 and the response to injury. Immunol Res. 1989; 8(2):118-29.
Score: 0.014
-
Romero R, Durum S, Dinarello CA, Oyarzun E, Hobbins JC, Mitchell MD. Interleukin-1 stimulates prostaglandin biosynthesis by human amnion. Prostaglandins. 1989 Jan; 37(1):13-22.
Score: 0.014
-
Tredget EE, Yu YM, Zhong S, Burini R, Okusawa S, Gelfand JA, Dinarello CA, Young VR, Burke JF. Role of interleukin 1 and tumor necrosis factor on energy metabolism in rabbits. Am J Physiol. 1988 Dec; 255(6 Pt 1):E760-8.
Score: 0.014
-
Mier JW, Vachino G, van der Meer JW, Numerof RP, Adams S, Cannon JG, Bernheim HA, Atkins MB, Parkinson DR, Dinarello CA. Induction of circulating tumor necrosis factor (TNF alpha) as the mechanism for the febrile response to interleukin-2 (IL-2) in cancer patients. J Clin Immunol. 1988 Nov; 8(6):426-36.
Score: 0.013
-
Bagby GC, Dinarello CA, Neerhout RC, Ridgway D, McCall E. Interleukin 1-dependent paracrine granulopoiesis in chronic granulocytic leukemia of the juvenile type. J Clin Invest. 1988 Oct; 82(4):1430-6.
Score: 0.013
-
Krogh Rasmussen A, Bech K, Feldt-Rasmussen U, Poulsen S, Holten I, Ryberg M, Dinarello CA, Siersbaek-Nielsen K, Friis T, Bendtzen K. Interleukin-1 affects the function of cultured human thyroid cells. Allergy. 1988 Aug; 43(6):435-41.
Score: 0.013
-
Haak-Frendscho M, Dinarello C, Kaplan AP. Recombinant human interleukin-1 beta causes histamine release from human basophils. J Allergy Clin Immunol. 1988 Aug; 82(2):218-23.
Score: 0.013
-
Okusawa S, Yancey KB, van der Meer JW, Endres S, Lonnemann G, Hefter K, Frank MM, Burke JF, Dinarello CA, Gelfand JA. C5a stimulates secretion of tumor necrosis factor from human mononuclear cells in vitro. Comparison with secretion of interleukin 1 beta and interleukin 1 alpha. J Exp Med. 1988 Jul 01; 168(1):443-8.
Score: 0.013
-
Vlassara H, Brownlee M, Manogue KR, Dinarello CA, Pasagian A. Cachectin/TNF and IL-1 induced by glucose-modified proteins: role in normal tissue remodeling. Science. 1988 Jun 10; 240(4858):1546-8.
Score: 0.013
-
Beasley D, Dinarello CA, Cannon JG. Interleukin-1 induces natriuresis in conscious rats: role of renal prostaglandins. Kidney Int. 1988 Jun; 33(6):1059-65.
Score: 0.013
-
Shaldon S, Dinarello C, Port F, Kluger M. Interleukin-1: the pros and cons of its clinical relevance. Artif Organs. 1988 Jun; 12(3):221.
Score: 0.013
-
Breder CD, Dinarello CA, Saper CB. Interleukin-1 immunoreactive innervation of the human hypothalamus. Science. 1988 Apr 15; 240(4850):321-4.
Score: 0.013
-
Domer FR, Mori K, Dinarello CA, Sokoloff L. Effects of leukocytic pyrogen (interleukin-1) on local cerebral glucose utilization in rats with and without premedication with indomethacin or dexamethasone. J Cereb Blood Flow Metab. 1988 Apr; 8(2):173-8.
Score: 0.013
-
van der Meer JW, Endres S, Lonnemann G, Cannon JG, Ikejima T, Okusawa S, Gelfand JA, Dinarello CA. Concentrations of immunoreactive human tumor necrosis factor alpha produced by human mononuclear cells in vitro. J Leukoc Biol. 1988 Mar; 43(3):216-23.
Score: 0.013
-
Wogensen LD, Mandrup-Poulsen T, Markholst H, Mølvig J, Lernmark A, Holst JJ, Dinarello CA, Nerup J. Interleukin-1 potentiates glucose stimulated insulin release in the isolated perfused pancreas. Acta Endocrinol (Copenh). 1988 Mar; 117(3):302-6.
Score: 0.013
-
Dinarello CA, Cannon JG, Wolff SM. New concepts on the pathogenesis of fever. Rev Infect Dis. 1988 Jan-Feb; 10(1):168-89.
Score: 0.013
-
Shaldon S, Dinarello CA, Koch KM, Lonnemann G, Bingel M, Granolleras C, Deschodt G, Branger B, Oulès R, Fourcade J. Interleukin-1 and dialysis. Adv Nephrol Necker Hosp. 1988; 17:423-34.
Score: 0.013
-
Conti P, Reale M, Angeletti PU, Dinarello CA. Restoration of anti-interleukin-1 depressed natural killer activity by human recombinant interferon alpha or gamma, human recombinant interleukin-2 and indomethacin. Int J Immunopharmacol. 1988; 10(8):907-11.
Score: 0.013
-
Zsebo KM, Yuschenkoff VN, Schiffer S, Chang D, McCall E, Dinarello CA, Brown MA, Altrock B, Bagby GC. Vascular endothelial cells and granulopoiesis: interleukin-1 stimulates release of G-CSF and GM-CSF. Blood. 1988 Jan; 71(1):99-103.
Score: 0.013
-
Bingel M, Lonnemann G, Koch KM, Dinarello CA, Shaldon S. Plasma interleukin-1 activity during hemodialysis: the influence of dialysis membranes. Nephron. 1988; 50(4):273-6.
Score: 0.013
-
Shaldon S, Dinarello C, Elie M, Koch KM. Interleukin-1 and biocompatibility in haemodialysis. Contrib Nephrol. 1988; 62:128-31.
Score: 0.013
-
Knudsen PJ, Dinarello CA, Strom TB. Glucocorticoids inhibit transcriptional and post-transcriptional expression of interleukin 1 in U937 cells. J Immunol. 1987 Dec 15; 139(12):4129-34.
Score: 0.013
-
Mandrup-Poulsen T, Bendtzen K, Dinarello CA, Nerup J. Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity. J Immunol. 1987 Dec 15; 139(12):4077-82.
Score: 0.013
-
Jandl RC, George JL, Dinarello CA, Schur PH. The effect of interleukin 1 on IgG synthesis in systemic lupus erythematosus. Clin Immunol Immunopathol. 1987 Dec; 45(3):384-94.
Score: 0.013
-
Tocco-Bradley R, Georgieff M, Jones CT, Moldawer LL, Dinarello CA, Blackburn GL, Bistrian BR. Changes in energy expenditure and fat metabolism in rats infused with interleukin-1. Eur J Clin Invest. 1987 Dec; 17(6):504-10.
Score: 0.013
-
Kandel RA, Dinarello CA, Biswas C. The stimulation of collagenase production in rabbit articular chondrocytes by interleukin-1 is increased by collagens. Biochem Int. 1987 Nov; 15(5):1021-31.
Score: 0.013
-
Bishai I, Dinarello CA, Coceani F. Prostaglandin formation in feline cerebral microvessels: effect of endotoxin and interleukin-1. Can J Physiol Pharmacol. 1987 Nov; 65(11):2225-30.
Score: 0.013
-
Okusawa S, Dinarello CA, Yancey KB, Endres S, Lawley TJ, Frank MM, Burke JF, Gelfand JA. C5a induction of human interleukin 1. Synergistic effect with endotoxin or interferon-gamma. J Immunol. 1987 Oct 15; 139(8):2635-40.
Score: 0.013
-
Dinarello CA, Mier JW. Lymphokines. N Engl J Med. 1987 Oct 08; 317(15):940-5.
Score: 0.013
-
Bochner BS, Landy SD, Plaut M, Dinarello CA, Schleimer RP. Interleukin 1 production by human lung tissue. I. Identification and characterization. J Immunol. 1987 Oct 01; 139(7):2297-302.
Score: 0.012
-
Van Damme J, De Ley M, Van Snick J, Dinarello CA, Billiau A. The role of interferon-beta 1 and the 26-kDa protein (interferon-beta 2) as mediators of the antiviral effect of interleukin 1 and tumor necrosis factor. J Immunol. 1987 Sep 15; 139(6):1867-72.
Score: 0.012
-
Mier JW, Dinarello CA, Atkins MB, Punsal PI, Perlmutter DH. Regulation of hepatic acute phase protein synthesis by products of interleukin 2 (IL 2)-stimulated human peripheral blood mononuclear cells. J Immunol. 1987 Aug 15; 139(4):1268-72.
Score: 0.012
-
Roh MS, Drazenovich KA, Barbose JJ, Dinarello CA, Cobb CF. Direct stimulation of the adrenal cortex by interleukin-1. Surgery. 1987 Aug; 102(2):140-6.
Score: 0.012
-
Spinas GA, Hansen BS, Linde S, Kastern W, Mølvig J, Mandrup-Poulsen T, Dinarello CA, Nielsen JH, Nerup J. Interleukin 1 dose-dependently affects the biosynthesis of (pro)insulin in isolated rat islets of Langerhans. Diabetologia. 1987 Jul; 30(7):474-80.
Score: 0.012
-
McClain CJ, Cohen D, Ott L, Dinarello CA, Young B. Ventricular fluid interleukin-1 activity in patients with head injury. J Lab Clin Med. 1987 Jul; 110(1):48-54.
Score: 0.012
-
Shoham S, Davenne D, Cady AB, Dinarello CA, Krueger JM. Recombinant tumor necrosis factor and interleukin 1 enhance slow-wave sleep. Am J Physiol. 1987 Jul; 253(1 Pt 2):R142-9.
Score: 0.012
-
Mannie MD, Dinarello CA, Paterson PY. Interleukin 1 and myelin basic protein synergistically augment adoptive transfer activity of lymphocytes mediating experimental autoimmune encephalomyelitis in Lewis rats. J Immunol. 1987 Jun 15; 138(12):4229-35.
Score: 0.012
-
White CW, Ghezzi P, Dinarello CA, Caldwell SA, McMurtry IF, Repine JE. Recombinant tumor necrosis factor/cachectin and interleukin 1 pretreatment decreases lung oxidized glutathione accumulation, lung injury, and mortality in rats exposed to hyperoxia. J Clin Invest. 1987 Jun; 79(6):1868-73.
Score: 0.012
-
Tan ZS, Beiser AS, Vasan RS, Roubenoff R, Dinarello CA, Harris TB, Benjamin EJ, Au R, Kiel DP, Wolf PA, Seshadri S. Inflammatory markers and the risk of Alzheimer disease: the Framingham Study. Neurology. 2007 May 29; 68(22):1902-8.
Score: 0.012
-
Georgilis K, Schaefer C, Dinarello CA, Klempner MS. Human recombinant interleukin 1 beta has no effect on intracellular calcium or on functional responses of human neutrophils. J Immunol. 1987 May 15; 138(10):3403-7.
Score: 0.012
-
Riveau GR, Novitsky TJ, Roslansky PF, Dinarello CA, Warren HS. Role of interleukin-1 in augmenting serum neutralization of bacterial lipopolysaccharide. J Clin Microbiol. 1987 May; 25(5):889-92.
Score: 0.012
-
Le PT, Tuck DT, Dinarello CA, Haynes BF, Singer KH. Human thymic epithelial cells produce interleukin 1. J Immunol. 1987 Apr 15; 138(8):2520-6.
Score: 0.012
-
Drabik MD, Schnure FC, Mok KT, Moldawer LL, Dinarello CA, Blackburn GL, Bistrian BR. Effect of protein depletion and short-term parenteral refeeding on the host response to interleukin 1 administration. J Lab Clin Med. 1987 Apr; 109(4):509-16.
Score: 0.012
-
Dejana E, Breviario F, Erroi A, Bussolino F, Mussoni L, Gramse M, Pintucci G, Casali B, Dinarello CA, Van Damme J, et al. Modulation of endothelial cell functions by different molecular species of interleukin 1. Blood. 1987 Feb; 69(2):695-9.
Score: 0.012
-
Naylor AM, Gubitz GJ, Dinarello CA, Veale WL. Central effects of vasopressin and 1-desamino-8-D-arginine vasopressin (DDAVP) on interleukin-1 fever in the rat. Brain Res. 1987 Jan 13; 401(1):173-7.
Score: 0.012
-
Bingel M, Lonnemann G, Koch KM, Dinarello CA, Shaldon S. Enhancement of in-vitro human interleukin-1 production by sodium acetate. Lancet. 1987 Jan 03; 1(8523):14-6.
Score: 0.012
-
Shaldon S, Dinarello CA, Wyler DJ. Induction of interleukin-1 during CAPD. Contrib Nephrol. 1987; 57:207-12.
Score: 0.012
-
Zucali JR, Broxmeyer HE, Dinarello CA, Gross MA, Weiner RS. Regulation of early human hematopoietic (BFU-E and CFU-GEMM) progenitor cells in vitro by interleukin 1-induced fibroblast-conditioned medium. Blood. 1987 Jan; 69(1):33-7.
Score: 0.012
-
Movat HZ, Cybulsky MI, Colditz IG, Chan MK, Dinarello CA. Acute inflammation in gram-negative infection: endotoxin, interleukin 1, tumor necrosis factor, and neutrophils. Fed Proc. 1987 Jan; 46(1):97-104.
Score: 0.012
-
Dinarello CA, Dempsey RA, Allegretta M, LoPreste G, Dainiak N, Parkinson DR, Mier JW. Inhibitory effects of elevated temperature on human cytokine production and natural killer activity. Cancer Res. 1986 Dec; 46(12 Pt 1):6236-41.
Score: 0.012
-
Spinas GA, Mandrup-Poulsen T, Mølvig J, Baek L, Bendtzen K, Dinarello CA, Nerup J. Low concentrations of interleukin-1 stimulate and high concentrations inhibit insulin release from isolated rat islets of Langerhans. Acta Endocrinol (Copenh). 1986 Dec; 113(4):551-8.
Score: 0.012
-
Knudsen PJ, Dinarello CA, Strom TB. Prostaglandins posttranscriptionally inhibit monocyte expression of interleukin 1 activity by increasing intracellular cyclic adenosine monophosphate. J Immunol. 1986 Nov 15; 137(10):3189-94.
Score: 0.012
-
Bagby GC, Dinarello CA, Wallace P, Wagner C, Hefeneider S, McCall E. Interleukin 1 stimulates granulocyte macrophage colony-stimulating activity release by vascular endothelial cells. J Clin Invest. 1986 Nov; 78(5):1316-23.
Score: 0.012
-
Evans WJ, Meredith CN, Cannon JG, Dinarello CA, Frontera WR, Hughes VA, Jones BH, Knuttgen HG. Metabolic changes following eccentric exercise in trained and untrained men. J Appl Physiol (1985). 1986 Nov; 61(5):1864-8.
Score: 0.012
-
McClain CJ, Cohen DA, Dinarello CA, Cannon JG, Shedlofsky SI, Kaplan AM. Serum interleukin-1 (IL-1) activity in alcoholic hepatitis. Life Sci. 1986 Oct 20; 39(16):1479-85.
Score: 0.012
-
Dustin ML, Rothlein R, Bhan AK, Dinarello CA, Springer TA. Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J Immunol. 1986 Jul 01; 137(1):245-54.
Score: 0.011
-
Rosenwasser LJ, Webb AC, Clark BD, Irie S, Chang L, Dinarello CA, Gehrke L, Wolff SM, Rich A, Auron PE. Expression of biologically active human interleukin 1 subpeptides by transfected simian COS cells. Proc Natl Acad Sci U S A. 1986 Jul; 83(14):5243-6.
Score: 0.011
-
Bendtzen K, Mandrup-Poulsen T, Nerup J, Nielsen JH, Dinarello CA, Svenson M. Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans. Science. 1986 Jun 20; 232(4757):1545-7.
Score: 0.011
-
Zucali JR, Dinarello CA, Oblon DJ, Gross MA, Anderson L, Weiner RS. Interleukin 1 stimulates fibroblasts to produce granulocyte-macrophage colony-stimulating activity and prostaglandin E2. J Clin Invest. 1986 Jun; 77(6):1857-63.
Score: 0.011
-
Perlmutter DH, Goldberger G, Dinarello CA, Mizel SB, Colten HR. Regulation of class III major histocompatibility complex gene products by interleukin-1. Science. 1986 May 16; 232(4752):850-2.
Score: 0.011
-
Lotz M, Tsoukas CD, Fong S, Dinarello CA, Carson DA, Vaughan JH. Release of lymphokines after infection with Epstein Barr virus in vitro. II. A monocyte-dependent inhibitor of interleukin 1 downregulates the production of interleukin 2 and interferon-gamma in rheumatoid arthritis. J Immunol. 1986 May 15; 136(10):3643-8.
Score: 0.011
-
Knudsen PJ, Dinarello CA, Strom TB. Purification and characterization of a unique human interleukin 1 from the tumor cell line U937. J Immunol. 1986 May 01; 136(9):3311-6.
Score: 0.011
-
Roh MS, Moldawer LL, Ekman LG, Dinarello CA, Bistrian BR, Jeevanandam M, Brennan MF. Stimulatory effect of interleukin-1 upon hepatic metabolism. Metabolism. 1986 May; 35(5):419-24.
Score: 0.011
-
Lachman LB, Dinarello CA, Llansa ND, Fidler IJ. Natural and recombinant human interleukin 1-beta is cytotoxic for human melanoma cells. J Immunol. 1986 Apr 15; 136(8):3098-102.
Score: 0.011
-
Miossec P, Dinarello CA, Ziff M. Interleukin-1 lymphocyte chemotactic activity in rheumatoid arthritis synovial fluid. Arthritis Rheum. 1986 Apr; 29(4):461-70.
Score: 0.011
-
Hamawy KJ, Yamazaki K, Georgieff M, Dinarello CA, Moldawer LL, Blackburn GL, Bistrian BR. Improvements in host immunity by partially purified interleukin 1 in rats with portacaval anastomosis and splenectomy. JPEN J Parenter Enteral Nutr. 1986 Mar-Apr; 10(2):146-50.
Score: 0.011
-
Joosten LA, Netea MG, Kim SH, Yoon DY, Oppers-Walgreen B, Radstake TR, Barrera P, van de Loo FA, Dinarello CA, van den Berg WB. IL-32, a proinflammatory cytokine in rheumatoid arthritis. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3298-303.
Score: 0.011
-
Wolff SM, Auron PE, Dinarello CA, Rosenwasser LJ, Webb AC, Rich A. Clone controversy at Immunex. Nature. 1986 Jan 23-29; 319(6051):270.
Score: 0.011
-
Walter J, Davenne D, Shoham S, Dinarello CA, Krueger JM. Brain temperature changes coupled to sleep states persist during interleukin 1-enhanced sleep. Am J Physiol. 1986 Jan; 250(1 Pt 2):R96-103.
Score: 0.011
-
Hamby BA, Huggins EM, Lachman LB, Dinarello CA, Sigel MM. Fish lymphocytes respond to human IL-1. Lymphokine Res. 1986; 5(2):157-62.
Score: 0.011
-
Mandrup-Poulsen T, Bendtzen K, Nerup J, Dinarello CA, Svenson M, Nielsen JH. Affinity-purified human interleukin I is cytotoxic to isolated islets of Langerhans. Diabetologia. 1986 Jan; 29(1):63-7.
Score: 0.011
-
Song X, Krelin Y, Dvorkin T, Bjorkdahl O, Segal S, Dinarello CA, Voronov E, Apte RN. CD11b+/Gr-1+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1beta-secreting cells. J Immunol. 2005 Dec 15; 175(12):8200-8.
Score: 0.011
-
Ahmed MS, Llanos-Q J, Dinarello CA, Blatteis CM. Interleukin 1 reduces opioid binding in guinea pig brain. Peptides. 1985 Nov-Dec; 6(6):1149-54.
Score: 0.011
-
Herman J, Dinarello CA, Kew MC, Rabson AR. The role of interleukin 1 (IL 1) in tumor-NK cell interactions: correction of defective NK cell activity in cancer patients by treating target cells with IL 1. J Immunol. 1985 Oct; 135(4):2882-6.
Score: 0.011
-
Stern DM, Bank I, Nawroth PP, Cassimeris J, Kisiel W, Fenton JW, Dinarello C, Chess L, Jaffe EA. Self-regulation of procoagulant events on the endothelial cell surface. J Exp Med. 1985 Oct 01; 162(4):1223-35.
Score: 0.011
-
Williams JM, Deloria D, Hansen JA, Dinarello CA, Loertscher R, Shapiro HM, Strom TB. The events of primary T cell activation can be staged by use of Sepharose-bound anti-T3 (64.1) monoclonal antibody and purified interleukin 1. J Immunol. 1985 Oct; 135(4):2249-55.
Score: 0.011
-
Ramadori G, Sipe JD, Dinarello CA, Mizel SB, Colten HR. Pretranslational modulation of acute phase hepatic protein synthesis by murine recombinant interleukin 1 (IL-1) and purified human IL-1. J Exp Med. 1985 Sep 01; 162(3):930-42.
Score: 0.011
-
Watters JM, Bessey PQ, Dinarello CA, Wolff SM, Wilmore DW. The induction of interleukin-1 in humans and its metabolic effects. Surgery. 1985 Aug; 98(2):298-306.
Score: 0.011
-
Chu ET, Lareau M, Rosenwasser LJ, Dinarello CA, Geha RS. Antigen presentation by EBV-B cells to resting and activated T cells: role of interleukin 1. J Immunol. 1985 Mar; 134(3):1676-81.
Score: 0.010
-
Wang W, Faubel S, Ljubanovic D, Mitra A, Falk SA, Kim J, Tao Y, Soloviev A, Reznikov LL, Dinarello CA, Schrier RW, Edelstein CL. Endotoxemic acute renal failure is attenuated in caspase-1-deficient mice. Am J Physiol Renal Physiol. 2005 May; 288(5):F997-1004.
Score: 0.010
-
Shaldon S, Koch KM, Quellhorst E, Lonnemann G, Dinarello CA. CAPD is a second-class treatment. Contrib Nephrol. 1985; 44:163-72.
Score: 0.010
-
Sahasrabuddhe CG, Dinarello C, Martin B, Maizel AL. Intracellular human IL-1: a precursor for the secreted monokine. Lymphokine Res. 1985; 4(3):205-13.
Score: 0.010
-
Williams JM, Dinarello CA, Rosenwasser LJ, Kelley V, Reddish M, Strom TB. Phorbol myristate acetate-protein complex mimics bioactivity of human IL-1. 1. Direct evidence that PMA temporarily enters and is released from cellular compartment during superinduction protocol. Lymphokine Res. 1985; 4(4):275-97.
Score: 0.010
-
Auron PE, Rosenwasser LJ, Matsushima K, Copeland T, Dinarello CA, Oppenheim JJ, Webb AC. Human and murine interleukin 1 possess sequence and structural similarities. J Mol Cell Immunol. 1985; 2(3):169-77.
Score: 0.010
-
Kaye J, Gillis S, Mizel SB, Shevach EM, Malek TR, Dinarello CA, Lachman LB, Janeway CA. Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2. J Immunol. 1984 Sep; 133(3):1339-45.
Score: 0.010
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Pearson FC, Bohon J, Lee W, Bruszer G, Sagona M, Dawe R, Jakubowski G, Morrison D, Dinarello C. Comparison of chemical analyses of hollow-fiber dialyzer extracts. Artif Organs. 1984 Aug; 8(3):291-8.
Score: 0.010
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Falkoff RJ, Butler JL, Dinarello CA, Fauci AS. Direct effects of a monoclonal B cell differentiation factor and of purified interleukin 1 on B cell differentiation. J Immunol. 1984 Aug; 133(2):692-6.
Score: 0.010
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Chu ET, Rosenwasser LJ, Dinarello CA, Rosen FS, Geha RS. Immunodeficiency with defective T-cell response to interleukin 1. Proc Natl Acad Sci U S A. 1984 Aug; 81(15):4945-9.
Score: 0.010
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Sauder DN, Dinarello CA, Morhenn VB. Langerhans cell production of interleukin-1. J Invest Dermatol. 1984 Jun; 82(6):605-7.
Score: 0.010
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Krueger JM, Walter J, Dinarello CA, Wolff SM, Chedid L. Sleep-promoting effects of endogenous pyrogen (interleukin-1). Am J Physiol. 1984 Jun; 246(6 Pt 2):R994-9.
Score: 0.010
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Ikejima T, Dinarello CA, Gill DM, Wolff SM. Induction of human interleukin-1 by a product of Staphylococcus aureus associated with toxic shock syndrome. J Clin Invest. 1984 May; 73(5):1312-20.
Score: 0.010
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Chu E, Rosenwasser LJ, Dinarello CA, Lareau M, Geha RS. Role of interleukin 1 in antigen-specific T cell proliferation. J Immunol. 1984 Mar; 132(3):1311-6.
Score: 0.010
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Bendtzen K, Baek L, Berild D, Hasselbach H, Dinarello CA, Wolff SM. Demonstration of circulating leukocytic pyrogen/interleukin-1 during fever. N Engl J Med. 1984 Mar 01; 310(9):596.
Score: 0.010
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Wang M, Sankula R, Tsai BM, Meldrum KK, Turrentine M, March KL, Brown JW, Dinarello CA, Meldrum DR. P38 MAPK mediates myocardial proinflammatory cytokine production and endotoxin-induced contractile suppression. Shock. 2004 Feb; 21(2):170-4.
Score: 0.010
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Sauder DN, Mounessa NL, Katz SI, Dinarello CA, Gallin JI. Chemotactic cytokines: the role of leukocytic pyrogen and epidermal cell thymocyte-activating factor in neutrophil chemotaxis. J Immunol. 1984 Feb; 132(2):828-32.
Score: 0.010
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Park JW, Taube C, Swasey C, Kodama T, Joetham A, Balhorn A, Takeda K, Miyahara N, Allen CB, Dakhama A, Kim SH, Dinarello CA, Gelfand EW. Interleukin-1 receptor antagonist attenuates airway hyperresponsiveness following exposure to ozone. Am J Respir Cell Mol Biol. 2004 Jun; 30(6):830-6.
Score: 0.010
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Sobrado J, Moldawer LL, Bistrian BR, Dinarello CA, Blackburn GL. Effect of ibuprofen on fever and metabolic changes induced by continuous infusion of leukocytic pyrogen (interleukin 1) or endotoxin. Infect Immun. 1983 Dec; 42(3):997-1005.
Score: 0.010
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Falkoff RJ, Muraguchi A, Hong JX, Butler JL, Dinarello CA, Fauci AS. The effects of interleukin 1 on human B cell activation and proliferation. J Immunol. 1983 Aug; 131(2):801-5.
Score: 0.009
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Wood DD, Ihrie EJ, Dinarello CA, Cohen PL. Isolation of an interleukin-1-like factor from human joint effusions. Arthritis Rheum. 1983 Aug; 26(8):975-83.
Score: 0.009
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Coceani F, Bishai I, Dinarello CA, Fitzpatrick FA. Prostaglandin E2 and thromboxane B2 in cerebrospinal fluid of afebrile and febrile cat. Am J Physiol. 1983 Jun; 244(6):R785-93.
Score: 0.009
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Baracos V, Rodemann HP, Dinarello CA, Goldberg AL. Stimulation of muscle protein degradation and prostaglandin E2 release by leukocytic pyrogen (interleukin-1). A mechanism for the increased degradation of muscle proteins during fever. N Engl J Med. 1983 Mar 10; 308(10):553-8.
Score: 0.009
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Banda NK, Vondracek A, Kraus D, Dinarello CA, Kim SH, Bendele A, Senaldi G, Arend WP. Mechanisms of inhibition of collagen-induced arthritis by murine IL-18 binding protein. J Immunol. 2003 Feb 15; 170(4):2100-5.
Score: 0.009
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Dempsey RA, Dinarello CA, Mier JW, Rosenwasser LJ, Allegretta M, Brown TE, Parkinson DR. The differential effects of human leukocyte pyrogen/lymphocyte-activating factor, T cell growth factor, and interferon on human natural killer activity. J Immunol. 1982 Dec; 129(6):2504-10.
Score: 0.009
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Raeburn CD, Dinarello CA, Zimmerman MA, Calkins CM, Pomerantz BJ, McIntyre RC, Harken AH, Meng X. Neutralization of IL-18 attenuates lipopolysaccharide-induced myocardial dysfunction. Am J Physiol Heart Circ Physiol. 2002 Aug; 283(2):H650-7.
Score: 0.009
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Stuyt RJ, Netea MG, Verschueren I, Fantuzzi G, Dinarello CA, Van Der Meer JW, Kullberg BJ. Role of interleukin-18 in host defense against disseminated Candida albicans infection. Infect Immun. 2002 Jun; 70(6):3284-6.
Score: 0.009
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Dinarello CA, Wolff SM. Molecular basis of fever in humans. Am J Med. 1982 May; 72(5):799-819.
Score: 0.009
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Netea MG, Kullberg BJ, Galama JM, Stalenhoef AF, Dinarello CA, Van der Meer JW. Non-LPS components of Chlamydia pneumoniae stimulate cytokine production through Toll-like receptor 2-dependent pathways. Eur J Immunol. 2002 04; 32(4):1188-95.
Score: 0.009
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Leoni F, Zaliani A, Bertolini G, Porro G, Pagani P, Pozzi P, Donà G, Fossati G, Sozzani S, Azam T, Bufler P, Fantuzzi G, Goncharov I, Kim SH, Pomerantz BJ, Reznikov LL, Siegmund B, Dinarello CA, Mascagni P. The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines. Proc Natl Acad Sci U S A. 2002 Mar 05; 99(5):2995-3000.
Score: 0.008
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Dinarello CA, Rosenwasser LJ, Wolff SM. Demonstration of a circulating suppressor factor of thymocyte proliferation during endotoxin fever in humans. J Immunol. 1981 Dec; 127(6):2517-9.
Score: 0.008
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Rosenwasser LJ, Dinarello CA. Ability of human leukocytic pyrogen to enhance phytohemagglutinin induced murine thymocyte proliferation. Cell Immunol. 1981 Sep 01; 63(1):134-42.
Score: 0.008
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Lee SJ, Cho YS, Cho MC, Shim JH, Lee KA, Ko KK, Choe YK, Park SN, Hoshino T, Kim S, Dinarello CA, Yoon DY. Both E6 and E7 oncoproteins of human papillomavirus 16 inhibit IL-18-induced IFN-gamma production in human peripheral blood mononuclear and NK cells. J Immunol. 2001 Jul 01; 167(1):497-504.
Score: 0.008
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Hong TP, Andersen NA, Nielsen K, Karlsen AE, Fantuzzi G, Eizirik DL, Dinarello CA, Mandrup-Poulsen T. Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma. Eur Cytokine Netw. 2000 Jun; 11(2):193-205.
Score: 0.008
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Biasucci LM, Liuzzo G, Fantuzzi G, Caligiuri G, Rebuzzi AG, Ginnetti F, Dinarello CA, Maseri A. Increasing levels of interleukin (IL)-1Ra and IL-6 during the first 2 days of hospitalization in unstable angina are associated with increased risk of in-hospital coronary events. Circulation. 1999 Apr 27; 99(16):2079-84.
Score: 0.007
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Freeman LM, Rush JE, Kehayias JJ, Ross JN, Meydani SN, Brown DJ, Dolnikowski GG, Marmor BN, White ME, Dinarello CA, Roubenoff R. Nutritional alterations and the effect of fish oil supplementation in dogs with heart failure. J Vet Intern Med. 1998 Nov-Dec; 12(6):440-8.
Score: 0.007
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Kaplanski G, Fabrigoule M, Boulay V, Dinarello CA, Bongrand P, Kaplanski S, Farnarier C. Thrombin induces endothelial type II activation in vitro: IL-1 and TNF-alpha-independent IL-8 secretion and E-selectin expression. J Immunol. 1997 Jun 01; 158(11):5435-41.
Score: 0.006
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Benigni F, Fantuzzi G, Sacco S, Sironi M, Pozzi P, Dinarello CA, Sipe JD, Poli V, Cappelletti M, Paonessa G, Pennica D, Panayotatos N, Ghezzi P. Six different cytokines that share GP130 as a receptor subunit, induce serum amyloid A and potentiate the induction of interleukin-6 and the activation of the hypothalamus-pituitary-adrenal axis by interleukin-1. Blood. 1996 Mar 01; 87(5):1851-4.
Score: 0.006
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Tilg H, Atkins MB, Dinarello CA, Mier JW. Induction of circulating interleukin 10 by interleukin 1 and interleukin 2, but not interleukin 6 immunotherapy. Cytokine. 1995 Oct; 7(7):734-9.
Score: 0.005
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Angel JB, Saget BM, Wang MZ, Wang A, Dinarello CA, Skolnik PR. Interleukin-10 enhances human immunodeficiency virus type 1 expression in a chronically infected promonocytic cell line (U1) by a tumor necrosis factor alpha-independent mechanism. J Interferon Cytokine Res. 1995 Jun; 15(6):575-84.
Score: 0.005
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Chomarat P, Vannier E, Dechanet J, Rissoan MC, Banchereau J, Dinarello CA, Miossec P. Balance of IL-1 receptor antagonist/IL-1 beta in rheumatoid synovium and its regulation by IL-4 and IL-10. J Immunol. 1995 Feb 01; 154(3):1432-9.
Score: 0.005
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Mancilla-Ramírez J, Dinarello CA, Santos-Preciado JI. [Phosphatidylcholine induces an increase in the production of interleukin-6 and improves survival of rats with neonatal sepsis caused by Klebsiella pneumoniae]. Gac Med Mex. 1995 Jan-Feb; 131(1):14-22.
Score: 0.005
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Mandrup-Poulsen T, Wogensen LD, Jensen M, Svensson P, Nilsson P, Emdal T, Mølvig J, Dinarello CA, Nerup J. Circulating interleukin-1 receptor antagonist concentrations are increased in adult patients with thermal injury. Crit Care Med. 1995 Jan; 23(1):26-33.
Score: 0.005
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Latini R, Bianchi M, Correale E, Dinarello CA, Fantuzzi G, Fresco C, Maggioni AP, Mengozzi M, Romano S, Shapiro L, et al. Cytokines in acute myocardial infarction: selective increase in circulating tumor necrosis factor, its soluble receptor, and interleukin-1 receptor antagonist. J Cardiovasc Pharmacol. 1994 Jan; 23(1):1-6.
Score: 0.005
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Pociot F, Rønningen KS, Bergholdt R, Lorenzen T, Johannesen J, Ye K, Dinarello CA, Nerup J. Genetic susceptibility markers in Danish patients with type 1 (insulin-dependent) diabetes--evidence for polygenicity in man. Danish Study Group of Diabetes in Childhood. Autoimmunity. 1994; 19(3):169-78.
Score: 0.005
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Erroi A, Fantuzzi G, Mengozzi M, Sironi M, Orencole SF, Clark BD, Dinarello CA, Isetta A, Gnocchi P, Giovarelli M, et al. Differential regulation of cytokine production in lipopolysaccharide tolerance in mice. Infect Immun. 1993 Oct; 61(10):4356-9.
Score: 0.005
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Meydani SN, Lichtenstein AH, Cornwall S, Meydani M, Goldin BR, Rasmussen H, Dinarello CA, Schaefer EJ. Immunologic effects of national cholesterol education panel step-2 diets with and without fish-derived N-3 fatty acid enrichment. J Clin Invest. 1993 Jul; 92(1):105-13.
Score: 0.005
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Santos AA, Scheltinga MR, Lynch E, Brown EF, Lawton P, Chambers E, Browning J, Dinarello CA, Wolff SM, Wilmore DW. Elaboration of interleukin 1-receptor antagonist is not attenuated by glucocorticoids after endotoxemia. Arch Surg. 1993 Feb; 128(2):138-43; discussion 143-4.
Score: 0.005
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Re F, Mengozzi M, Muzio M, Dinarello CA, Mantovani A, Colotta F. Expression of interleukin-1 receptor antagonist (IL-1ra) by human circulating polymorphonuclear cells. Eur J Immunol. 1993 Feb; 23(2):570-3.
Score: 0.005
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Feingold KR, Staprans I, Memon RA, Moser AH, Shigenaga JK, Doerrler W, Dinarello CA, Grunfeld C. Endotoxin rapidly induces changes in lipid metabolism that produce hypertriglyceridemia: low doses stimulate hepatic triglyceride production while high doses inhibit clearance. J Lipid Res. 1992 Dec; 33(12):1765-76.
Score: 0.004
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Numerof RP, Sipe JD, Trehu EG, Dinarello CA, Mier JW. Suppression of IL-2-induced SAA gene expression in mice by the administration of an IL-1 receptor antagonist. Cytokine. 1992 Nov; 4(6):555-60.
Score: 0.004
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Romero R, Sepulveda W, Mazor M, Brandt F, Cotton DB, Dinarello CA, Mitchell MD. The natural interleukin-1 receptor antagonist in term and preterm parturition. Am J Obstet Gynecol. 1992 Oct; 167(4 Pt 1):863-72.
Score: 0.004
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Avraham H, Vannier E, Cowley S, Jiang SX, Chi S, Dinarello CA, Zsebo KM, Groopman JE. Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells. Blood. 1992 Jan 15; 79(2):365-71.
Score: 0.004
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Houba V, Berger FM, Dinarello CA, Johnson AG, Le J, Mauël J, Van der Meer JW, Philippeaux MM, Vilcek J, Vogels MT. Protodyne: an immunostimulatory protein component, prepared from gram-positive Bacillus subtilis. Dev Biol Stand. 1992; 77:121-8.
Score: 0.004
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Grunfeld C, Soued M, Adi S, Moser AH, Fiers W, Dinarello CA, Feingold KR. Interleukin 4 inhibits stimulation of hepatic lipogenesis by tumor necrosis factor, interleukin 1, and interleukin 6 but not by interferon-alpha. Cancer Res. 1991 Jun 01; 51(11):2803-7.
Score: 0.004
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Molina JM, Schindler R, Ferriani R, Sakaguchi M, Vannier E, Dinarello CA, Groopman JE. Production of cytokines by peripheral blood monocytes/macrophages infected with human immunodeficiency virus type 1 (HIV-1). J Infect Dis. 1990 May; 161(5):888-93.
Score: 0.004
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Loppnow H, Dürrbaum I, Brade H, Dinarello CA, Kusumoto S, Rietschel ET, Flad HD. Lipid A, the immunostimulatory principle of lipopolysaccharides? Adv Exp Med Biol. 1990; 256:561-6.
Score: 0.004
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Prakash S, Dinarello CA, Danko K, Stadecker MJ, Wyler DJ. Schistosomal egg granuloma-derived fibroblast-stimulating factor is apparently distinct from interleukin-1. Infect Immun. 1989 Mar; 57(3):679-84.
Score: 0.003
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White CW, Ghezzi P, McMahon S, Dinarello CA, Repine JE. Cytokines increase rat lung antioxidant enzymes during exposure to hyperoxia. J Appl Physiol (1985). 1989 Feb; 66(2):1003-7.
Score: 0.003
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Michie HR, Manogue KR, Spriggs DR, Revhaug A, O'Dwyer S, Dinarello CA, Cerami A, Wolff SM, Wilmore DW. Detection of circulating tumor necrosis factor after endotoxin administration. N Engl J Med. 1988 Jun 09; 318(23):1481-6.
Score: 0.003
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Tagaya Y, Okada M, Sugie K, Kasahara T, Kondo N, Hamuro J, Matsushima K, Dinarello CA, Yodoi J. IL-2 receptor(p55)/Tac-inducing factor. Purification and characterization of adult T cell leukemia-derived factor. J Immunol. 1988 Apr 15; 140(8):2614-20.
Score: 0.003
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Rustgi VK, Jones DB, Dinarello CA, Hoofnagle JH. Lymphokines and bile secretion in the rat. Liver. 1987 Jun; 7(3):149-54.
Score: 0.003
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Fauci AS, Rosenberg SA, Sherwin SA, Dinarello CA, Longo DL, Lane HC. NIH conference. Immunomodulators in clinical medicine. Ann Intern Med. 1987 Mar; 106(3):421-33.
Score: 0.003
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Perlmutter DH, Dinarello CA, Punsal PI, Colten HR. Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression. J Clin Invest. 1986 Nov; 78(5):1349-54.
Score: 0.003
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Lotz M, Tsoukas CD, Robinson CA, Dinarello CA, Carson DA, Vaughan JH. Basis for defective responses of rheumatoid arthritis synovial fluid lymphocytes to anti-CD3 (T3) antibodies. J Clin Invest. 1986 Sep; 78(3):713-21.
Score: 0.003
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Lotz M, Tsoukas CD, Fong S, Dinarello CA, Carson DA, Vaughan JH. Release of lymphokines after Epstein Barr virus infection in vitro. I. Sources of and kinetics of production of interferons and interleukins in normal humans. J Immunol. 1986 May 15; 136(10):3636-42.
Score: 0.003
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Peters M, Butler JL, Margolick JB, Gerrard TL, Dinarello CA, Fauci AS. Synergy of helper factors in the differentiation of in vivo-preactivated antigen-specific human B cells. Cell Immunol. 1985 Mar; 91(1):33-42.
Score: 0.003
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Loda M, Clowes GH, Dinarello CA, George BC, Lane B, Richardson W. Induction of hepatic protein synthesis by a peptide in blood plasma of patients with sepsis and trauma. Surgery. 1984 Aug; 96(2):204-13.
Score: 0.003
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Wyler DJ, Stadecker MJ, Dinarello CA, O'Dea JF. Fibroblast stimulation in schistosomiasis. V. Egg granuloma macrophages spontaneously secrete a fibroblast-stimulating factor. J Immunol. 1984 Jun; 132(6):3142-8.
Score: 0.002
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Beer DJ, Dinarello CA, Rosenwasser LJ, Rocklin RE. Human monocyte-derived soluble product(s) has an accessory function in the generation of histamine- and concanavalin A-induced suppressor T cells. J Clin Invest. 1982 Aug; 70(2):393-400.
Score: 0.002
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McAdam KP, Li J, Knowles J, Foss NT, Dinarello CA, Rosenwasser LJ, Selinger MJ, Kaplan MM, Goodman R, Herbert PN, Bausserman LL, Nadler LM. The biology of SAA: identification of the inducer, in vitro synthesis, and heterogeneity demonstrated with monoclonal antibodies. Ann N Y Acad Sci. 1982; 389:126-36.
Score: 0.002
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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