 Connection
Robert Kuchta to DNA Primase
This is a "connection" page, showing publications Robert Kuchta has written about DNA Primase.
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5.479 |
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Dickerson SM, Kuchta RD. Protein Displacement by Herpes Helicase-Primase and the Key Role of UL42 during Helicase-Coupled DNA Synthesis by the Herpes Polymerase. Biochemistry. 2017 05 30; 56(21):2651-2662.
Score: 0.543
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Weller SK, Kuchta RD. The DNA helicase-primase complex as a target for herpes viral infection. Expert Opin Ther Targets. 2013 Oct; 17(10):1119-32.
Score: 0.418
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Urban M, Joubert N, Purse BW, Hocek M, Kuchta RD. Mechanisms by which human DNA primase chooses to polymerize a nucleoside triphosphate. Biochemistry. 2010 Feb 02; 49(4):727-35.
Score: 0.328
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Urban M, Joubert N, Hocek M, Alexander RE, Kuchta RD. Herpes simplex virus-1 DNA primase: a remarkably inaccurate yet selective polymerase. Biochemistry. 2009 Nov 24; 48(46):10866-81.
Score: 0.323
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Cavanaugh NA, Ramirez-Aguilar KA, Urban M, Kuchta RD. Herpes simplex virus-1 helicase-primase: roles of each subunit in DNA binding and phosphodiester bond formation. Biochemistry. 2009 Nov 03; 48(43):10199-207.
Score: 0.322
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Kuchta RD, Stengel G. Mechanism and evolution of DNA primases. Biochim Biophys Acta. 2010 May; 1804(5):1180-9.
Score: 0.314
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Cavanaugh NA, Kuchta RD. Initiation of new DNA strands by the herpes simplex virus-1 primase-helicase complex and either herpes DNA polymerase or human DNA polymerase alpha. J Biol Chem. 2009 Jan 16; 284(3):1523-32.
Score: 0.301
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Keller KE, Cavanaugh N, Kuchta RD. Interaction of herpes primase with the sugar of a NTP. Biochemistry. 2008 Aug 26; 47(34):8977-84.
Score: 0.295
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Ramirez-Aguilar KA, Moore CL, Kuchta RD. Herpes simplex virus 1 primase employs watson-crick hydrogen bonding to identify cognate nucleoside triphosphates. Biochemistry. 2005 Nov 29; 44(47):15585-93.
Score: 0.245
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Richardson KA, Vega TP, Richardson FC, Moore CL, Rohloff JC, Tomkinson B, Bendele RA, Kuchta RD. Polymerization of the triphosphates of AraC, 2',2'-difluorodeoxycytidine (dFdC) and OSI-7836 (T-araC) by human DNA polymerase alpha and DNA primase. Biochem Pharmacol. 2004 Dec 15; 68(12):2337-46.
Score: 0.229
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Moore CL, Zivkovic A, Engels JW, Kuchta RD. Human DNA primase uses Watson-Crick hydrogen bonds to distinguish between correct and incorrect nucleoside triphosphates. Biochemistry. 2004 Sep 28; 43(38):12367-74.
Score: 0.226
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Ramirez-Aguilar KA, Kuchta RD. Herpes simplex virus-1 primase: a polymerase with extraordinarily low fidelity. Biochemistry. 2004 Jul 20; 43(28):9084-91.
Score: 0.223
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Moore CL, Chiaramonte M, Higgins T, Kuchta RD. Synthesis of nucleotide analogues that potently and selectively inhibit human DNA primase. Biochemistry. 2002 Nov 26; 41(47):14066-75.
Score: 0.199
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Zerbe LK, Kuchta RD. The p58 subunit of human DNA primase is important for primer initiation, elongation, and counting. Biochemistry. 2002 Apr 16; 41(15):4891-900.
Score: 0.191
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Arezi B, Kuchta RD. Eukaryotic DNA primase. Trends Biochem Sci. 2000 Nov; 25(11):572-6.
Score: 0.172
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Arezi B, Kirk BW, Copeland WC, Kuchta RD. Interactions of DNA with human DNA primase monitored with photoactivatable cross-linking agents: implications for the role of the p58 subunit. Biochemistry. 1999 Sep 28; 38(39):12899-907.
Score: 0.160
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Zerbe LK, Goodman MF, Efrati E, Kuchta RD. Abasic template lesions are strong chain terminators for DNA primase but not for DNA polymerase alpha during the synthesis of new DNA strands. Biochemistry. 1999 Sep 28; 38(39):12908-14.
Score: 0.160
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Kirk BW, Kuchta RD. Human DNA primase: anion inhibition, manganese stimulation, and their effects on in vitro start-site selection. Biochemistry. 1999 Aug 03; 38(31):10126-34.
Score: 0.158
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Kirk BW, Kuchta RD. Arg304 of human DNA primase is a key contributor to catalysis and NTP binding: primase and the family X polymerases share significant sequence homology. Biochemistry. 1999 Jun 15; 38(24):7727-36.
Score: 0.157
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Chen Y, Bai P, Mackay S, Korza G, Carson JH, Kuchta RD, Weller SK. Herpes simplex virus type 1 helicase-primase: DNA binding and consequent protein oligomerization and primase activation. J Virol. 2011 Jan; 85(2):968-78.
Score: 0.086
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Ramirez-Aguilar KA, Kuchta RD. Mechanism of primer synthesis by the herpes simplex virus 1 helicase-primase. Biochemistry. 2004 Feb 17; 43(6):1754-62.
Score: 0.054
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Ramirez-Aguilar KA, Low-Nam NA, Kuchta RD. Key role of template sequence for primer synthesis by the herpes simplex virus 1 helicase-primase. Biochemistry. 2002 Dec 10; 41(49):14569-79.
Score: 0.050
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Richardson FC, Kuchta RD, Mazurkiewicz A, Richardson KA. Polymerization of 2'-fluoro- and 2'-O-methyl-dNTPs by human DNA polymerase alpha, polymerase gamma, and primase. Biochem Pharmacol. 2000 May 01; 59(9):1045-52.
Score: 0.042
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Kirk BW, Harrington C, Perrino FW, Kuchta RD. Eucaryotic DNA primase does not prefer to synthesize primers at pyrimidine rich DNA sequences when nucleoside triphosphates are present at concentrations found in whole cells. Biochemistry. 1997 Jun 03; 36(22):6725-31.
Score: 0.034
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Kuchta RD. Isotopic assays of viral polymerases and related proteins. Methods Enzymol. 1996; 275:241-57.
Score: 0.031
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Catalano CE, Kuchta RD. Inactivation of DNA polymerase alpha-primase by acrolein: loss of activity depends on the DNA substrate. Biochem Biophys Res Commun. 1995 Sep 25; 214(3):971-7.
Score: 0.030
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Thompson HC, Kuchta RD. Arabinofuranosyl nucleotides are not chain-terminators during initiation of new strands of DNA by DNA polymerase alpha-primase. Biochemistry. 1995 Sep 05; 34(35):11198-203.
Score: 0.030
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Ilsley DD, Lee SH, Miller WH, Kuchta RD. Acyclic guanosine analogs inhibit DNA polymerases alpha, delta, and epsilon with very different potencies and have unique mechanisms of action. Biochemistry. 1995 Feb 28; 34(8):2504-10.
Score: 0.029
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Sheaff RJ, Kuchta RD. Misincorporation of nucleotides by calf thymus DNA primase and elongation of primers containing multiple noncognate nucleotides by DNA polymerase alpha. J Biol Chem. 1994 Jul 29; 269(30):19225-31.
Score: 0.028
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Sheaff RJ, Kuchta RD. Mechanism of calf thymus DNA primase: slow initiation, rapid polymerization, and intelligent termination. Biochemistry. 1993 Mar 30; 32(12):3027-37.
Score: 0.025
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Kuchta RD, Ilsley D, Kravig KD, Schubert S, Harris B. Inhibition of DNA primase and polymerase alpha by arabinofuranosylnucleoside triphosphates and related compounds. Biochemistry. 1992 May 19; 31(19):4720-8.
Score: 0.024
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Kuchta RD, Willhelm L. Inhibition of DNA primase by 9-beta-D-arabinofuranosyladenosine triphosphate. Biochemistry. 1991 Jan 22; 30(3):797-803.
Score: 0.022
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Kuchta RD, Reid B, Chang LM. DNA primase. Processivity and the primase to polymerase alpha activity switch. J Biol Chem. 1990 Sep 25; 265(27):16158-65.
Score: 0.021
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Sheaff RJ, Kuchta RD, Ilsley D. Calf thymus DNA polymerase alpha-primase: "communication" and primer-template movement between the two active sites. Biochemistry. 1994 Mar 01; 33(8):2247-54.
Score: 0.007
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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