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Connection

Robert Kuchta to Humans

This is a "connection" page, showing publications Robert Kuchta has written about Humans.

 
Connection Strength
 
 
 
0.222
 
  1. Vashishtha AK, Kuchta RD. Polymerase and exonuclease activities in herpes simplex virus type 1 DNA polymerase are not highly coordinated. Biochemistry. 2015 Jan 20; 54(2):240-9.
    View in: PubMed
    Score: 0.012
  2. Weller SK, Kuchta RD. The DNA helicase-primase complex as a target for herpes viral infection. Expert Opin Ther Targets. 2013 Oct; 17(10):1119-32.
    View in: PubMed
    Score: 0.011
  3. Lund TJ, Cavanaugh NA, Joubert N, Urban M, Patro JN, Hocek M, Kuchta RD. B family DNA polymerases asymmetrically recognize pyrimidines and purines. Biochemistry. 2011 Aug 23; 50(33):7243-50.
    View in: PubMed
    Score: 0.010
  4. Stengel G, Purse BW, Kuchta RD. Effect of transition metal ions on the fluorescence and Taq-catalyzed polymerase chain reaction of tricyclic cytidine analogs. Anal Biochem. 2011 Sep 01; 416(1):53-60.
    View in: PubMed
    Score: 0.009
  5. Urban M, Joubert N, Purse BW, Hocek M, Kuchta RD. Mechanisms by which human DNA primase chooses to polymerize a nucleoside triphosphate. Biochemistry. 2010 Feb 02; 49(4):727-35.
    View in: PubMed
    Score: 0.009
  6. Patro JN, Urban M, Kuchta RD. Interaction of human DNA polymerase alpha and DNA polymerase I from Bacillus stearothermophilus with hypoxanthine and 8-oxoguanine nucleotides. Biochemistry. 2009 Sep 01; 48(34):8271-8.
    View in: PubMed
    Score: 0.008
  7. Stengel G, Purse BW, Wilhelmsson LM, Urban M, Kuchta RD. Ambivalent incorporation of the fluorescent cytosine analogues tC and tCo by human DNA polymerase alpha and Klenow fragment. Biochemistry. 2009 Aug 11; 48(31):7547-55.
    View in: PubMed
    Score: 0.008
  8. Shewach DS, Kuchta RD. Introduction to cancer chemotherapeutics. Chem Rev. 2009 Jul; 109(7):2859-61.
    View in: PubMed
    Score: 0.008
  9. Kuchta RD, Stengel G. Mechanism and evolution of DNA primases. Biochim Biophys Acta. 2010 May; 1804(5):1180-9.
    View in: PubMed
    Score: 0.008
  10. Cavanaugh NA, Urban M, Beckman J, Spratt TE, Kuchta RD. Identifying the features of purine dNTPs that allow accurate and efficient DNA replication by herpes simplex virus I DNA polymerase. Biochemistry. 2009 Apr 21; 48(15):3554-64.
    View in: PubMed
    Score: 0.008
  11. Patro JN, Urban M, Kuchta RD. Role of the 2-amino group of purines during dNTP polymerization by human DNA polymerase alpha. Biochemistry. 2009 Jan 13; 48(1):180-9.
    View in: PubMed
    Score: 0.008
  12. Cavanaugh NA, Kuchta RD. Initiation of new DNA strands by the herpes simplex virus-1 primase-helicase complex and either herpes DNA polymerase or human DNA polymerase alpha. J Biol Chem. 2009 Jan 16; 284(3):1523-32.
    View in: PubMed
    Score: 0.008
  13. Keller KE, Cavanaugh N, Kuchta RD. Interaction of herpes primase with the sugar of a NTP. Biochemistry. 2008 Aug 26; 47(34):8977-84.
    View in: PubMed
    Score: 0.008
  14. Beckman J, Kincaid K, Hocek M, Spratt T, Engels J, Cosstick R, Kuchta RD. Human DNA polymerase alpha uses a combination of positive and negative selectivity to polymerize purine dNTPs with high fidelity. Biochemistry. 2007 Jan 16; 46(2):448-60.
    View in: PubMed
    Score: 0.007
  15. Richardson KA, Vega TP, Richardson FC, Moore CL, Rohloff JC, Tomkinson B, Bendele RA, Kuchta RD. Polymerization of the triphosphates of AraC, 2',2'-difluorodeoxycytidine (dFdC) and OSI-7836 (T-araC) by human DNA polymerase alpha and DNA primase. Biochem Pharmacol. 2004 Dec 15; 68(12):2337-46.
    View in: PubMed
    Score: 0.006
  16. Moore CL, Zivkovic A, Engels JW, Kuchta RD. Human DNA primase uses Watson-Crick hydrogen bonds to distinguish between correct and incorrect nucleoside triphosphates. Biochemistry. 2004 Sep 28; 43(38):12367-74.
    View in: PubMed
    Score: 0.006
  17. Bricelj A, Dora Ng YL, Gobec M, Kuchta R, Hu W, Javornik ?, Ro?ic M, G?tschow M, Zheng G, Kr?nke J, Steinebach C, Sosic I. Design, Synthesis, and Evaluation of BCL-2 Targeting PROTACs. Chemistry. 2024 Aug 12; 30(45):e202400430.
    View in: PubMed
    Score: 0.006
  18. Chiaramonte M, Moore CL, Kincaid K, Kuchta RD. Facile polymerization of dNTPs bearing unnatural base analogues by DNA polymerase alpha and Klenow fragment (DNA polymerase I). Biochemistry. 2003 Sep 09; 42(35):10472-81.
    View in: PubMed
    Score: 0.006
  19. Moore CL, Chiaramonte M, Higgins T, Kuchta RD. Synthesis of nucleotide analogues that potently and selectively inhibit human DNA primase. Biochemistry. 2002 Nov 26; 41(47):14066-75.
    View in: PubMed
    Score: 0.005
  20. Zerbe LK, Kuchta RD. The p58 subunit of human DNA primase is important for primer initiation, elongation, and counting. Biochemistry. 2002 Apr 16; 41(15):4891-900.
    View in: PubMed
    Score: 0.005
  21. Arezi B, Kuchta RD. Eukaryotic DNA primase. Trends Biochem Sci. 2000 Nov; 25(11):572-6.
    View in: PubMed
    Score: 0.005
  22. Steet RA, Melancon P, Kuchta RD. 3'-Azidothymidine potently inhibits the biosynthesis of highly branched N-linked oligosaccharides and poly-N-acetyllactosamine chains in cells. J Biol Chem. 2000 Sep 01; 275(35):26812-20.
    View in: PubMed
    Score: 0.005
  23. Arezi B, Kirk BW, Copeland WC, Kuchta RD. Interactions of DNA with human DNA primase monitored with photoactivatable cross-linking agents: implications for the role of the p58 subunit. Biochemistry. 1999 Sep 28; 38(39):12899-907.
    View in: PubMed
    Score: 0.004
  24. Kirk BW, Kuchta RD. Human DNA primase: anion inhibition, manganese stimulation, and their effects on in vitro start-site selection. Biochemistry. 1999 Aug 03; 38(31):10126-34.
    View in: PubMed
    Score: 0.004
  25. Kirk BW, Kuchta RD. Arg304 of human DNA primase is a key contributor to catalysis and NTP binding: primase and the family X polymerases share significant sequence homology. Biochemistry. 1999 Jun 15; 38(24):7727-36.
    View in: PubMed
    Score: 0.004
  26. Romaszko J, Cymes I, Draganska E, Kuchta R, Glinska-Lewczuk K. Mortality among the homeless: Causes and meteorological relationships. PLoS One. 2017; 12(12):e0189938.
    View in: PubMed
    Score: 0.004
  27. Romaszko J, Kuchta R, Opalach C, Bertrand-Bucinska A, Romaszko AM, Giergielewicz-Januszko B, Bucinski A. Socioeconomic Characteristics, Health Risk Factors and Alcohol Consumption among the Homeless in North-Eastern Part of Poland. Cent Eur J Public Health. 2017 Mar; 25(1):29-34.
    View in: PubMed
    Score: 0.004
  28. Opalach C, Romaszko J, Jaracz M, Kuchta R, Borkowska A, Bucinski A. Coping Styles and Alcohol Dependence among Homeless People. PLoS One. 2016; 11(9):e0162381.
    View in: PubMed
    Score: 0.003
  29. Kuchta RD. Isotopic assays of viral polymerases and related proteins. Methods Enzymol. 1996; 275:241-57.
    View in: PubMed
    Score: 0.003
  30. Ilsley DD, Lee SH, Miller WH, Kuchta RD. Acyclic guanosine analogs inhibit DNA polymerases alpha, delta, and epsilon with very different potencies and have unique mechanisms of action. Biochemistry. 1995 Feb 28; 34(8):2504-10.
    View in: PubMed
    Score: 0.003
  31. Hall ET, Yan JP, Melan?on P, Kuchta RD. 3'-Azido-3'-deoxythymidine potently inhibits protein glycosylation. A novel mechanism for AZT cytotoxicity. J Biol Chem. 1994 May 20; 269(20):14355-8.
    View in: PubMed
    Score: 0.003
  32. Ungermannova D, Parker SJ, Nasveschuk CG, Chapnick DA, Phillips AJ, Kuchta RD, Liu X. Identification and mechanistic studies of a novel ubiquitin E1 inhibitor. J Biomol Screen. 2012 Apr; 17(4):421-34.
    View in: PubMed
    Score: 0.002
  33. Ungermannova D, Parker SJ, Nasveschuk CG, Wang W, Quade B, Zhang G, Kuchta RD, Phillips AJ, Liu X. Largazole and its derivatives selectively inhibit ubiquitin activating enzyme (e1). PLoS One. 2012; 7(1):e29208.
    View in: PubMed
    Score: 0.002
  34. Sun T, Yang X, Wang W, Zhang X, Xu Q, Zhu S, Kuchta R, Chen G, Liu X. Cellular abundance of Mps1 and the role of its carboxyl terminal tail in substrate recruitment. J Biol Chem. 2010 Dec 03; 285(49):38730-9.
    View in: PubMed
    Score: 0.002
  35. Johnson LM, Hansen RR, Urban M, Kuchta RD, Bowman CN. Photoinitiator nucleotide for quantifying nucleic Acid hybridization. Biomacromolecules. 2010 Apr 12; 11(4):1133-8.
    View in: PubMed
    Score: 0.002
  36. Townsend MB, Smagala JA, Dawson ED, Deyde V, Gubareva L, Klimov AI, Kuchta RD, Rowlen KL. Detection of adamantane-resistant influenza on a microarray. J Clin Virol. 2008 Jun; 42(2):117-23.
    View in: PubMed
    Score: 0.002
  37. Dankbar DM, Dawson ED, Mehlmann M, Moore CL, Smagala JA, Shaw MW, Cox NJ, Kuchta RD, Rowlen KL. Diagnostic microarray for influenza B viruses. Anal Chem. 2007 Mar 01; 79(5):2084-90.
    View in: PubMed
    Score: 0.002
  38. Mehlmann M, Bonner AB, Williams JV, Dankbar DM, Moore CL, Kuchta RD, Podsiad AB, Tamerius JD, Dawson ED, Rowlen KL. Comparison of the MChip to viral culture, reverse transcription-PCR, and the QuickVue influenza A+B test for rapid diagnosis of influenza. J Clin Microbiol. 2007 Apr; 45(4):1234-7.
    View in: PubMed
    Score: 0.002
  39. Dawson ED, Moore CL, Dankbar DM, Mehlmann M, Townsend MB, Smagala JA, Smith CB, Cox NJ, Kuchta RD, Rowlen KL. Identification of A/H5N1 influenza viruses using a single gene diagnostic microarray. Anal Chem. 2007 Jan 01; 79(1):378-84.
    View in: PubMed
    Score: 0.002
  40. Dawson ED, Moore CL, Smagala JA, Dankbar DM, Mehlmann M, Townsend MB, Smith CB, Cox NJ, Kuchta RD, Rowlen KL. MChip: a tool for influenza surveillance. Anal Chem. 2006 Nov 15; 78(22):7610-5.
    View in: PubMed
    Score: 0.002
  41. Richards OC, Spagnolo JF, Lyle JM, Vleck SE, Kuchta RD, Kirkegaard K. Intramolecular and intermolecular uridylylation by poliovirus RNA-dependent RNA polymerase. J Virol. 2006 Aug; 80(15):7405-15.
    View in: PubMed
    Score: 0.002
  42. Townsend MB, Dawson ED, Mehlmann M, Smagala JA, Dankbar DM, Moore CL, Smith CB, Cox NJ, Kuchta RD, Rowlen KL. Experimental evaluation of the FluChip diagnostic microarray for influenza virus surveillance. J Clin Microbiol. 2006 Aug; 44(8):2863-71.
    View in: PubMed
    Score: 0.002
  43. Richardson FC, Kuchta RD, Mazurkiewicz A, Richardson KA. Polymerization of 2'-fluoro- and 2'-O-methyl-dNTPs by human DNA polymerase alpha, polymerase gamma, and primase. Biochem Pharmacol. 2000 May 01; 59(9):1045-52.
    View in: PubMed
    Score: 0.001
  44. Yan JP, Ilsley DD, Frohlick C, Steet R, Hall ET, Kuchta RD, Melan?on P. 3'-Azidothymidine (zidovudine) inhibits glycosylation and dramatically alters glycosphingolipid synthesis in whole cells at clinically relevant concentrations. J Biol Chem. 1995 Sep 29; 270(39):22836-41.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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