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Connection

Kenneth Tyler to Animals

This is a "connection" page, showing publications Kenneth Tyler has written about Animals.

 
Connection Strength
  
 
 
1.653
  
  1. Frost J, Rudy MJ, Leser JS, Tan H, Hu Y, Wang J, Clarke P, Tyler KL. Telaprevir Treatment Reduces Paralysis in a Mouse Model of Enterovirus D68 Acute Flaccid Myelitis. J Virol. 2023 05 31; 97(5):e0015623.
    View in: PubMed
    Score: 0.049
  2. Stonedahl S, Leser JS, Clarke P, Potter H, Boyd TD, Tyler KL. Treatment with Granulocyte-Macrophage Colony-Stimulating Factor Reduces Viral Titers in the Brains of West Nile Virus-Infected Mice and Improves Survival. J Virol. 2023 03 30; 97(3):e0180522.
    View in: PubMed
    Score: 0.048
  3. Pastula DM, Tyler KL. An Overview of Monkeypox Virus and Its Neuroinvasive Potential. Ann Neurol. 2022 10; 92(4):527-531.
    View in: PubMed
    Score: 0.046
  4. Rudy MJ, Frost J, Clarke P, Tyler KL. Neutralizing Antibody Given after Paralysis Onset Reduces the Severity of Paralysis Compared to Nonspecific Antibody-Treated Controls in a Mouse Model of EV-D68-Associated Acute Flaccid Myelitis. Antimicrob Agents Chemother. 2022 08 16; 66(8):e0022722.
    View in: PubMed
    Score: 0.046
  5. Stonedahl S, Leser JS, Clarke P, Tyler KL. Depletion of Microglia in an Ex Vivo Brain Slice Culture Model of West Nile Virus Infection Leads to Increased Viral Titers and Cell Death. Microbiol Spectr. 2022 04 27; 10(2):e0068522.
    View in: PubMed
    Score: 0.045
  6. Clarke P, Leser JS, Tyler KL. Intrinsic Innate Immune Responses Control Viral Growth and Protect against Neuronal Death in an Ex Vivo Model of West Nile Virus-Induced Central Nervous System Disease. J Virol. 2021 08 25; 95(18):e0083521.
    View in: PubMed
    Score: 0.043
  7. Rozental AJ, McGrath S, Mooney AP, Hinson SR, McKeon A, Pittock SJ, Gross CC, Tyler KL. Evaluation of cell-based and tissue-based immunofluorescent assays for detection of glial fibrillary acidic protein autoantibodies in the cerebrospinal fluid of dogs with meningoencephalitis of unknown origin and other central nervous system disorders. Am J Vet Res. 2021 Feb; 82(2):132-137.
    View in: PubMed
    Score: 0.042
  8. Potter H, Boyd TD, Clarke P, Pelak VS, Tyler KL. Recruiting the innate immune system with GM-CSF to fight viral diseases, including West Nile Virus encephalitis and COVID-19. F1000Res. 2020; 9:345.
    View in: PubMed
    Score: 0.040
  9. Hixon AM, Frost J, Rudy MJ, Messacar K, Clarke P, Tyler KL. Understanding Enterovirus D68-Induced Neurologic Disease: A Basic Science Review. Viruses. 2019 09 04; 11(9).
    View in: PubMed
    Score: 0.038
  10. Hixon AM, Clarke P, Tyler KL. Contemporary Circulating Enterovirus D68 Strains Infect and Undergo Retrograde Axonal Transport in Spinal Motor Neurons Independent of Sialic Acid. J Virol. 2019 08 15; 93(16).
    View in: PubMed
    Score: 0.038
  11. Clarke P, Zhuang Y, Berens HM, Leser JS, Tyler KL. Interferon Beta Contributes to Astrocyte Activation in the Brain following Reovirus Infection. J Virol. 2019 05 15; 93(10).
    View in: PubMed
    Score: 0.037
  12. Seitz S, Clarke P, Tyler KL. Pharmacologic Depletion of Microglia Increases Viral Load in the Brain and Enhances Mortality in Murine Models of Flavivirus-Induced Encephalitis. J Virol. 2018 08 15; 92(16).
    View in: PubMed
    Score: 0.035
  13. Hixon AM, Clarke P, Tyler KL. Evaluating Treatment Efficacy in a Mouse Model of Enterovirus D68-Associated Paralytic Myelitis. J Infect Dis. 2017 12 05; 216(10):1245-1253.
    View in: PubMed
    Score: 0.034
  14. Quick ED, Seitz S, Clarke P, Tyler KL. Minocycline Has Anti-inflammatory Effects and Reduces Cytotoxicity in an Ex Vivo Spinal Cord Slice Culture Model of West Nile Virus Infection. J Virol. 2017 11 15; 91(22).
    View in: PubMed
    Score: 0.033
  15. Hixon AM, Yu G, Leser JS, Yagi S, Clarke P, Chiu CY, Tyler KL. A mouse model of paralytic myelitis caused by enterovirus D68. PLoS Pathog. 2017 02; 13(2):e1006199.
    View in: PubMed
    Score: 0.032
  16. Zhuang Y, Berens-Norman HM, Leser JS, Clarke P, Tyler KL. Mitochondrial p53 Contributes to Reovirus-Induced Neuronal Apoptosis and Central Nervous System Injury in a Mouse Model of Viral Encephalitis. J Virol. 2016 09 01; 90(17):7684-91.
    View in: PubMed
    Score: 0.031
  17. Beckham JD, Pastula DM, Massey A, Tyler KL. Zika Virus as an Emerging Global Pathogen: Neurological Complications of Zika Virus. JAMA Neurol. 2016 Jul 01; 73(7):875-9.
    View in: PubMed
    Score: 0.030
  18. Pastula DM, Smith DE, Beckham JD, Tyler KL. Four emerging arboviral diseases in North America: Jamestown Canyon, Powassan, chikungunya, and Zika virus diseases. J Neurovirol. 2016 06; 22(3):257-60.
    View in: PubMed
    Score: 0.030
  19. Quick ED, Leser JS, Clarke P, Tyler KL. Activation of intrinsic immune responses and microglial phagocytosis in an ex vivo spinal cord slice culture model of West Nile virus infection. J Virol. 2014 Nov; 88(22):13005-14.
    View in: PubMed
    Score: 0.027
  20. Clarke P, Leser JS, Bowen RA, Tyler KL. Virus-induced transcriptional changes in the brain include the differential expression of genes associated with interferon, apoptosis, interleukin 17 receptor A, and glutamate signaling as well as flavivirus-specific upregulation of tRNA synthetases. mBio. 2014 Mar 11; 5(2):e00902-14.
    View in: PubMed
    Score: 0.026
  21. Oyer RJ, David Beckham J, Tyler KL. West Nile and St. Louis encephalitis viruses. Handb Clin Neurol. 2014; 123:433-47.
    View in: PubMed
    Score: 0.026
  22. Clarke P, Leser JS, Quick ED, Dionne KR, Beckham JD, Tyler KL. Death receptor-mediated apoptotic signaling is activated in the brain following infection with West Nile virus in the absence of a peripheral immune response. J Virol. 2014 Jan; 88(2):1080-9.
    View in: PubMed
    Score: 0.025
  23. Dionne KR, Tyler KL. Slice culture modeling of central nervous system (CNS) viral infection. Methods Mol Biol. 2013; 1078:97-117.
    View in: PubMed
    Score: 0.024
  24. Dionne KR, Galvin JM, Schittone SA, Clarke P, Tyler KL. Type I interferon signaling limits reoviral tropism within the brain and prevents lethal systemic infection. J Neurovirol. 2011 Aug; 17(4):314-26.
    View in: PubMed
    Score: 0.021
  25. Berens HM, Tyler KL. The proapoptotic Bcl-2 protein Bax plays an important role in the pathogenesis of reovirus encephalitis. J Virol. 2011 Apr; 85(8):3858-71.
    View in: PubMed
    Score: 0.021
  26. Dionne KR, Leser JS, Lorenzen KA, Beckham JD, Tyler KL. A brain slice culture model of viral encephalitis reveals an innate CNS cytokine response profile and the therapeutic potential of caspase inhibition. Exp Neurol. 2011 Apr; 228(2):222-31.
    View in: PubMed
    Score: 0.021
  27. Beckham JD, Tuttle KD, Tyler KL. Caspase-3 activation is required for reovirus-induced encephalitis in vivo. J Neurovirol. 2010 Jul; 16(4):306-17.
    View in: PubMed
    Score: 0.020
  28. Tyler KL, Leser JS, Phang TL, Clarke P. Gene expression in the brain during reovirus encephalitis. J Neurovirol. 2010 Feb; 16(1):56-71.
    View in: PubMed
    Score: 0.019
  29. Tyler KL. Emerging viral infections of the central nervous system: part 2. Arch Neurol. 2009 Sep; 66(9):1065-74.
    View in: PubMed
    Score: 0.019
  30. Tyler KL. Emerging viral infections of the central nervous system: part 1. Arch Neurol. 2009 Aug; 66(8):939-48.
    View in: PubMed
    Score: 0.019
  31. Clarke P, Beckham JD, Leser JS, Hoyt CC, Tyler KL. Fas-mediated apoptotic signaling in the mouse brain following reovirus infection. J Virol. 2009 Jun; 83(12):6161-70.
    View in: PubMed
    Score: 0.018
  32. Beckham JD, Tuttle K, Tyler KL. Reovirus activates transforming growth factor beta and bone morphogenetic protein signaling pathways in the central nervous system that contribute to neuronal survival following infection. J Virol. 2009 May; 83(10):5035-45.
    View in: PubMed
    Score: 0.018
  33. Clarke P, Tyler KL. Apoptosis in animal models of virus-induced disease. Nat Rev Microbiol. 2009 Feb; 7(2):144-55.
    View in: PubMed
    Score: 0.018
  34. Tyler KL. Neurological infections: advances in therapy, outcome, and prediction. Lancet Neurol. 2009 Jan; 8(1):19-21.
    View in: PubMed
    Score: 0.018
  35. Bosque PJ, Tyler KL. Prions' travels--feces and transmission of prion diseases. J Infect Dis. 2008 Jul 01; 198(1):8-9.
    View in: PubMed
    Score: 0.017
  36. Goody RJ, Schittone SA, Tyler KL. Experimental reovirus-induced acute flaccid paralysis and spinal motor neuron cell death. J Neuropathol Exp Neurol. 2008 Mar; 67(3):231-9.
    View in: PubMed
    Score: 0.017
  37. Goody RJ, Beckham JD, Rubtsova K, Tyler KL. JAK-STAT signaling pathways are activated in the brain following reovirus infection. J Neurovirol. 2007 Aug; 13(4):373-83.
    View in: PubMed
    Score: 0.016
  38. Beckham JD, Goody RJ, Clarke P, Bonny C, Tyler KL. Novel strategy for treatment of viral central nervous system infection by using a cell-permeating inhibitor of c-Jun N-terminal kinase. J Virol. 2007 Jul; 81(13):6984-92.
    View in: PubMed
    Score: 0.016
  39. Anderson CA, Bosque P, Filley CM, Arciniegas DB, Kleinschmidt-Demasters BK, Pape WJ, Tyler KL. Colorado surveillance program for chronic wasting disease transmission to humans: lessons from 2 highly suspicious but negative cases. Arch Neurol. 2007 Mar; 64(3):439-41.
    View in: PubMed
    Score: 0.016
  40. Davis LE, DeBiasi R, Goade DE, Haaland KY, Harrington JA, Harnar JB, Pergam SA, King MK, DeMasters BK, Tyler KL. West Nile virus neuroinvasive disease. Ann Neurol. 2006 Sep; 60(3):286-300.
    View in: PubMed
    Score: 0.015
  41. Debiasi RL, Tyler KL. West Nile virus meningoencephalitis. Nat Clin Pract Neurol. 2006 May; 2(5):264-75.
    View in: PubMed
    Score: 0.015
  42. Goody RJ, Hoyt CC, Tyler KL. Reovirus infection of the CNS enhances iNOS expression in areas of virus-induced injury. Exp Neurol. 2005 Oct; 195(2):379-90.
    View in: PubMed
    Score: 0.014
  43. Richardson-Burns SM, Tyler KL. Minocycline delays disease onset and mortality in reovirus encephalitis. Exp Neurol. 2005 Apr; 192(2):331-9.
    View in: PubMed
    Score: 0.014
  44. Hoyt CC, Richardson-Burns SM, Goody RJ, Robinson BA, Debiasi RL, Tyler KL. Nonstructural protein sigma1s is a determinant of reovirus virulence and influences the kinetics and severity of apoptosis induction in the heart and central nervous system. J Virol. 2005 Mar; 79(5):2743-53.
    View in: PubMed
    Score: 0.014
  45. Clarke P, Richardson-Burns SM, DeBiasi RL, Tyler KL. Mechanisms of apoptosis during reovirus infection. Curr Top Microbiol Immunol. 2005; 289:1-24.
    View in: PubMed
    Score: 0.014
  46. Clarke P, Debiasi RL, Goody R, Hoyt CC, Richardson-Burns S, Tyler KL. Mechanisms of reovirus-induced cell death and tissue injury: role of apoptosis and virus-induced perturbation of host-cell signaling and transcription factor activation. Viral Immunol. 2005; 18(1):89-115.
    View in: PubMed
    Score: 0.014
  47. DeBiasi RL, Robinson BA, Sherry B, Bouchard R, Brown RD, Rizeq M, Long C, Tyler KL. Caspase inhibition protects against reovirus-induced myocardial injury in vitro and in vivo. J Virol. 2004 Oct; 78(20):11040-50.
    View in: PubMed
    Score: 0.013
  48. Tyler KL. COMMENTARY: Gibbs CJ Jr, Amyx HL, Bacote A, Masters CL, Gajdusek DC. Oral transmission of kuru, Creutzfeldt-Jakob disease, and scrapie to nonhuman primates. J Infect Dis 1980; 142:205-208. J Infect Dis. 2004 Aug 01; 190(3):653-60.
    View in: PubMed
    Score: 0.013
  49. Tyler KL. West Nile virus infection in the United States. Arch Neurol. 2004 Aug; 61(8):1190-5.
    View in: PubMed
    Score: 0.013
  50. Richardson-Burns SM, Tyler KL. Regional differences in viral growth and central nervous system injury correlate with apoptosis. J Virol. 2004 May; 78(10):5466-75.
    View in: PubMed
    Score: 0.013
  51. Tyler KL, Barton ES, Ibach ML, Robinson C, Campbell JA, O'Donnell SM, Valyi-Nagy T, Clarke P, Wetzel JD, Dermody TS. Isolation and molecular characterization of a novel type 3 reovirus from a child with meningitis. J Infect Dis. 2004 May 01; 189(9):1664-75.
    View in: PubMed
    Score: 0.013
  52. Tyler KL. Update on herpes simplex encephalitis. Rev Neurol Dis. 2004; 1(4):169-78.
    View in: PubMed
    Score: 0.013
  53. DeBiasi RL, Clarke P, Meintzer S, Jotte R, Kleinschmidt-Demasters BK, Johnson GL, Tyler KL. Reovirus-induced alteration in expression of apoptosis and DNA repair genes with potential roles in viral pathogenesis. J Virol. 2003 Aug; 77(16):8934-47.
    View in: PubMed
    Score: 0.012
  54. Lane TR, Fu J, Sherry B, Tarbet B, Hurst BL, Riabova O, Kazakova E, Egorova A, Clarke P, Leser JS, Frost J, Rudy M, Tyler KL, Klose T, Volobueva AS, Belyaevskaya SV, Zarubaev VV, Kuhn RJ, Makarov V, Ekins S. Efficacy of an isoxazole-3-carboxamide analog of pleconaril in mouse models of Enterovirus-D68 and Coxsackie B5. Antiviral Res. 2023 08; 216:105654.
    View in: PubMed
    Score: 0.012
  55. Clarke P, Tyler KL. Reovirus-induced apoptosis: A minireview. Apoptosis. 2003 Mar; 8(2):141-50.
    View in: PubMed
    Score: 0.012
  56. Poggioli GJ, Dermody TS, Tyler KL. Reovirus-induced sigma1s-dependent G(2)/M phase cell cycle arrest is associated with inhibition of p34(cdc2). J Virol. 2001 Aug; 75(16):7429-34.
    View in: PubMed
    Score: 0.011
  57. DeBiasi RL, Edelstein CL, Sherry B, Tyler KL. Calpain inhibition protects against virus-induced apoptotic myocardial injury. J Virol. 2001 Jan; 75(1):351-61.
    View in: PubMed
    Score: 0.010
  58. Dionne KR, Tyler KL, Clarke P. Slice Culture Modeling of CNS Viral Infection. Methods Mol Biol. 2021; 2311:109-130.
    View in: PubMed
    Score: 0.010
  59. Tyler KL, Malessa R. The Goltz-Ferrier debates and the triumph of cerebral localizationalist theory. Neurology. 2000 Oct 10; 55(7):1015-24.
    View in: PubMed
    Score: 0.010
  60. Poggioli GJ, Keefer C, Connolly JL, Dermody TS, Tyler KL. Reovirus-induced G(2)/M cell cycle arrest requires sigma1s and occurs in the absence of apoptosis. J Virol. 2000 Oct; 74(20):9562-70.
    View in: PubMed
    Score: 0.010
  61. Gill CM, Kapadia RK, Beckham JD, Piquet AL, Tyler KL, Pastula DM. Usutu virus disease: a potential problem for North America? J Neurovirol. 2020 04; 26(2):149-154.
    View in: PubMed
    Score: 0.010
  62. Gill CM, Beckham JD, Piquet AL, Tyler KL, Pastula DM. Five Emerging Neuroinvasive Arboviral Diseases: Cache Valley, Eastern Equine Encephalitis, Jamestown Canyon, Powassan, and Usutu. Semin Neurol. 2019 08; 39(4):419-427.
    View in: PubMed
    Score: 0.009
  63. Bonney S, Seitz S, Ryan CA, Jones KL, Clarke P, Tyler KL, Siegenthaler JA. Gamma Interferon Alters Junctional Integrity via Rho Kinase, Resulting in Blood-Brain Barrier Leakage in Experimental Viral Encephalitis. mBio. 2019 08 06; 10(4).
    View in: PubMed
    Score: 0.009
  64. Debiasi RL, Squier MK, Pike B, Wynes M, Dermody TS, Cohen JJ, Tyler KL. Reovirus-induced apoptosis is preceded by increased cellular calpain activity and is blocked by calpain inhibitors. J Virol. 1999 Jan; 73(1):695-701.
    View in: PubMed
    Score: 0.009
  65. Tyler KL. Prions and prion diseases of the central nervous system. Curr Clin Top Infect Dis. 1999; 19:226-51.
    View in: PubMed
    Score: 0.009
  66. Pelosi E, Rozenberg F, Coen DM, Tyler KL. A herpes simplex virus DNA polymerase mutation that specifically attenuates neurovirulence in mice. Virology. 1998 Dec 20; 252(2):364-72.
    View in: PubMed
    Score: 0.009
  67. Brown DM, Hixon AM, Oldfield LM, Zhang Y, Novotny M, Wang W, Das SR, Shabman RS, Tyler KL, Scheuermann RH. Contemporary Circulating Enterovirus D68 Strains Have Acquired the Capacity for Viral Entry and Replication in Human Neuronal Cells. mBio. 2018 10 16; 9(5).
    View in: PubMed
    Score: 0.009
  68. Oberhaus SM, Dermody TS, Tyler KL. Apoptosis and the cytopathic effects of reovirus. Curr Top Microbiol Immunol. 1998; 233(Pt 2):23-49.
    View in: PubMed
    Score: 0.008
  69. Tyler KL. Pathogenesis of reovirus infections of the central nervous system. Curr Top Microbiol Immunol. 1998; 233(Pt 2):93-124.
    View in: PubMed
    Score: 0.008
  70. Virgin HW, Dermody TS, Tyler KL. Cellular and humoral immunity to reovirus infection. Curr Top Microbiol Immunol. 1998; 233(Pt 2):147-61.
    View in: PubMed
    Score: 0.008
  71. Hoon-Hanks LL, McGrath S, Tyler KL, Owen C, Stenglein MD. Metagenomic Investigation of Idiopathic Meningoencephalomyelitis in Dogs. J Vet Intern Med. 2018 Jan; 32(1):324-330.
    View in: PubMed
    Score: 0.008
  72. Shives KD, Tyler KL, Beckham JD. Molecular mechanisms of neuroinflammation and injury during acute viral encephalitis. J Neuroimmunol. 2017 07 15; 308:102-111.
    View in: PubMed
    Score: 0.008
  73. Oberhaus SM, Smith RL, Clayton GH, Dermody TS, Tyler KL. Reovirus infection and tissue injury in the mouse central nervous system are associated with apoptosis. J Virol. 1997 Mar; 71(3):2100-6.
    View in: PubMed
    Score: 0.008
  74. Tyler KL, Squier MK, Brown AL, Pike B, Willis D, Oberhaus SM, Dermody TS, Cohen JJ. Linkage between reovirus-induced apoptosis and inhibition of cellular DNA synthesis: role of the S1 and M2 genes. J Virol. 1996 Nov; 70(11):7984-91.
    View in: PubMed
    Score: 0.008
  75. Vasek MJ, Garber C, Dorsey D, Durrant DM, Bollman B, Soung A, Yu J, Perez-Torres C, Frouin A, Wilton DK, Funk K, DeMasters BK, Jiang X, Bowen JR, Mennerick S, Robinson JK, Garbow JR, Tyler KL, Suthar MS, Schmidt RE, Stevens B, Klein RS. A complement-microglial axis drives synapse loss during virus-induced memory impairment. Nature. 2016 06 23; 534(7608):538-43.
    View in: PubMed
    Score: 0.008
  76. Almond JW, Brown P, Gore SM, Hofman A, Wientjens PW, Ridley RM, Baker HF, Roberts GW, Tyler KL. Creutzfeldt-Jakob disease and bovine spongiform encephalopathy: any connection? BMJ. 1995 Nov 25; 311(7017):1415-21.
    View in: PubMed
    Score: 0.007
  77. Tyler KL, Squier MK, Rodgers SE, Schneider BE, Oberhaus SM, Grdina TA, Cohen JJ, Dermody TS. Differences in the capacity of reovirus strains to induce apoptosis are determined by the viral attachment protein sigma 1. J Virol. 1995 Nov; 69(11):6972-9.
    View in: PubMed
    Score: 0.007
  78. Dermody TS, Chappell JD, Hofler JG, Kramp W, Tyler KL. Eradication of persistent reovirus infection from a B-cell hybridoma. Virology. 1995 Sep 10; 212(1):272-6.
    View in: PubMed
    Score: 0.007
  79. Virgin HW, Mann MA, Tyler KL. Protective antibodies inhibit reovirus internalization and uncoating by intracellular proteases. J Virol. 1994 Oct; 68(10):6719-29.
    View in: PubMed
    Score: 0.007
  80. Tyler KL, Mann MA, Fields BN, Virgin HW. Protective anti-reovirus monoclonal antibodies and their effects on viral pathogenesis. J Virol. 1993 Jun; 67(6):3446-53.
    View in: PubMed
    Score: 0.006
  81. Dionne KR, Zhuang Y, Leser JS, Tyler KL, Clarke P. Daxx upregulation within the cytoplasm of reovirus-infected cells is mediated by interferon and contributes to apoptosis. J Virol. 2013 Mar; 87(6):3447-60.
    View in: PubMed
    Score: 0.006
  82. Beatman E, Oyer R, Shives KD, Hedman K, Brault AC, Tyler KL, Beckham JD. West Nile virus growth is independent of autophagy activation. Virology. 2012 Nov 10; 433(1):262-72.
    View in: PubMed
    Score: 0.006
  83. Schittone SA, Dionne KR, Tyler KL, Clarke P. Activation of innate immune responses in the central nervous system during reovirus myelitis. J Virol. 2012 Aug; 86(15):8107-18.
    View in: PubMed
    Score: 0.006
  84. Stankiewicz TR, Loucks FA, Schroeder EK, Nevalainen MT, Tyler KL, Aktories K, Bouchard RJ, Linseman DA. Signal transducer and activator of transcription-5 mediates neuronal apoptosis induced by inhibition of Rac GTPase activity. J Biol Chem. 2012 May 11; 287(20):16835-48.
    View in: PubMed
    Score: 0.006
  85. Virgin HW, Mann MA, Fields BN, Tyler KL. Monoclonal antibodies to reovirus reveal structure/function relationships between capsid proteins and genetics of susceptibility to antibody action. J Virol. 1991 Dec; 65(12):6772-81.
    View in: PubMed
    Score: 0.006
  86. Virgin HW, Tyler KL. Role of immune cells in protection against and control of reovirus infection in neonatal mice. J Virol. 1991 Oct; 65(10):5157-64.
    View in: PubMed
    Score: 0.005
  87. Bia MJ, Tyler K. Evidence that calcium channel blockade prevents cyclosporine-induced exacerbation of renal ischemic injury. Transplantation. 1991 Feb; 51(2):293-5.
    View in: PubMed
    Score: 0.005
  88. Blakely PK, Kleinschmidt-DeMasters BK, Tyler KL, Irani DN. Disrupted glutamate transporter expression in the spinal cord with acute flaccid paralysis caused by West Nile virus infection. J Neuropathol Exp Neurol. 2009 Oct; 68(10):1061-72.
    View in: PubMed
    Score: 0.005
  89. Tyler KL, Virgin HW, Bassel-Duby R, Fields BN. Antibody inhibits defined stages in the pathogenesis of reovirus serotype 3 infection of the central nervous system. J Exp Med. 1989 Sep 01; 170(3):887-900.
    View in: PubMed
    Score: 0.005
  90. Miyamoto SD, Brown RD, Robinson BA, Tyler KL, Long CS, Debiasi RL. Cardiac cell-specific apoptotic and cytokine responses to reovirus infection: determinants of myocarditic phenotype. J Card Fail. 2009 Aug; 15(6):529-39.
    View in: PubMed
    Score: 0.005
  91. Virgin HW, Bassel-Duby R, Fields BN, Tyler KL. Antibody protects against lethal infection with the neurally spreading reovirus type 3 (Dearing). J Virol. 1988 Dec; 62(12):4594-604.
    View in: PubMed
    Score: 0.004
  92. Zimmermann AK, Loucks FA, Schroeder EK, Bouchard RJ, Tyler KL, Linseman DA. Glutathione binding to the Bcl-2 homology-3 domain groove: a molecular basis for Bcl-2 antioxidant function at mitochondria. J Biol Chem. 2007 Oct 05; 282(40):29296-304.
    View in: PubMed
    Score: 0.004
  93. Tyler KL, McPhee DA, Fields BN. Distinct pathways of viral spread in the host determined by reovirus S1 gene segment. Science. 1986 Aug 15; 233(4765):770-4.
    View in: PubMed
    Score: 0.004
  94. Kaye KM, Spriggs DR, Bassel-Duby R, Fields BN, Tyler KL. Genetic basis for altered pathogenesis of an immune-selected antigenic variant of reovirus type 3 (Dearing). J Virol. 1986 Jul; 59(1):90-7.
    View in: PubMed
    Score: 0.004
  95. Le SS, Loucks FA, Udo H, Richardson-Burns S, Phelps RA, Bouchard RJ, Barth H, Aktories K, Tyler KL, Kandel ER, Heidenreich KA, Linseman DA. Inhibition of Rac GTPase triggers a c-Jun- and Bim-dependent mitochondrial apoptotic cascade in cerebellar granule neurons. J Neurochem. 2005 Aug; 94(4):1025-39.
    View in: PubMed
    Score: 0.004
  96. Tyler KL, Bronson RT, Byers KB, Fields B. Molecular basis of viral neurotropism: experimental reovirus infection. Neurology. 1985 Jan; 35(1):88-92.
    View in: PubMed
    Score: 0.003
  97. Edelmann KH, Richardson-Burns S, Alexopoulou L, Tyler KL, Flavell RA, Oldstone MB. Does Toll-like receptor 3 play a biological role in virus infections? Virology. 2004 May 01; 322(2):231-8.
    View in: PubMed
    Score: 0.003
  98. Cuevas BD, Abell AN, Witowsky JA, Yujiri T, Johnson NL, Kesavan K, Ware M, Jones PL, Weed SA, DeBiasi RL, Oka Y, Tyler KL, Johnson GL. MEKK1 regulates calpain-dependent proteolysis of focal adhesion proteins for rear-end detachment of migrating fibroblasts. EMBO J. 2003 Jul 01; 22(13):3346-55.
    View in: PubMed
    Score: 0.003
  99. Mann MA, Tyler KL, Knipe DM, Fields BN. Type 3 reovirus neuroinvasion after intramuscular inoculation: viral genetic determinants of lethality and spinal cord infection. Virology. 2002 Nov 25; 303(2):213-21.
    View in: PubMed
    Score: 0.003
  100. Yujiri T, Ware M, Widmann C, Oyer R, Russell D, Chan E, Zaitsu Y, Clarke P, Tyler K, Oka Y, Fanger GR, Henson P, Johnson GL. MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation. Proc Natl Acad Sci U S A. 2000 Jun 20; 97(13):7272-7.
    View in: PubMed
    Score: 0.003
  101. Connolly JL, Rodgers SE, Clarke P, Ballard DW, Kerr LD, Tyler KL, Dermody TS. Reovirus-induced apoptosis requires activation of transcription factor NF-kappaB. J Virol. 2000 Apr; 74(7):2981-9.
    View in: PubMed
    Score: 0.002
  102. Greenwood-Van Meerveld B, Tyler K, Kuge T, Ogata N. Anti-diarrhoeal effects of seirogan in the rat small intestine and colon examined in vitro. Aliment Pharmacol Ther. 1999 Jan; 13(1):97-102.
    View in: PubMed
    Score: 0.002
  103. Rodgers SE, Barton ES, Oberhaus SM, Pike B, Gibson CA, Tyler KL, Dermody TS. Reovirus-induced apoptosis of MDCK cells is not linked to viral yield and is blocked by Bcl-2. J Virol. 1997 Mar; 71(3):2540-6.
    View in: PubMed
    Score: 0.002
  104. Sherry B, Li XY, Tyler KL, Cullen JM, Virgin HW. Lymphocytes protect against and are not required for reovirus-induced myocarditis. J Virol. 1993 Oct; 67(10):6119-24.
    View in: PubMed
    Score: 0.002
  105. Sacks SL, Wanklin RJ, Reece DE, Hicks KA, Tyler KL, Coen DM. Progressive esophagitis from acyclovir-resistant herpes simplex. Clinical roles for DNA polymerase mutants and viral heterogeneity? Ann Intern Med. 1989 Dec 01; 111(11):893-9.
    View in: PubMed
    Score: 0.001
  106. Coen DM, Kosz-Vnenchak M, Jacobson JG, Leib DA, Bogard CL, Schaffer PA, Tyler KL, Knipe DM. Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate. Proc Natl Acad Sci U S A. 1989 Jun; 86(12):4736-40.
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    Score: 0.001
  107. Leib DA, Coen DM, Bogard CL, Hicks KA, Yager DR, Knipe DM, Tyler KL, Schaffer PA. Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency. J Virol. 1989 Feb; 63(2):759-68.
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    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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