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Connection

Kenneth Tyler to Brain

This is a "connection" page, showing publications Kenneth Tyler has written about Brain.

 
Connection Strength
 
 
 
3.164
 
  1. Stonedahl S, Leser JS, Clarke P, Potter H, Boyd TD, Tyler KL. Treatment with Granulocyte-Macrophage Colony-Stimulating Factor Reduces Viral Titers in the Brains of West Nile Virus-Infected Mice and Improves Survival. J Virol. 2023 03 30; 97(3):e0180522.
    View in: PubMed
    Score: 0.348
  2. Clarke P, Leser JS, Tyler KL. Intrinsic Innate Immune Responses Control Viral Growth and Protect against Neuronal Death in an Ex Vivo Model of West Nile Virus-Induced Central Nervous System Disease. J Virol. 2021 08 25; 95(18):e0083521.
    View in: PubMed
    Score: 0.313
  3. Seitz S, Clarke P, Tyler KL. Pharmacologic Depletion of Microglia Increases Viral Load in the Brain and Enhances Mortality in Murine Models of Flavivirus-Induced Encephalitis. J Virol. 2018 08 15; 92(16).
    View in: PubMed
    Score: 0.253
  4. Clarke P, Leser JS, Bowen RA, Tyler KL. Virus-induced transcriptional changes in the brain include the differential expression of genes associated with interferon, apoptosis, interleukin 17 receptor A, and glutamate signaling as well as flavivirus-specific upregulation of tRNA synthetases. mBio. 2014 Mar 11; 5(2):e00902-14.
    View in: PubMed
    Score: 0.187
  5. Clarke P, Leser JS, Quick ED, Dionne KR, Beckham JD, Tyler KL. Death receptor-mediated apoptotic signaling is activated in the brain following infection with West Nile virus in the absence of a peripheral immune response. J Virol. 2014 Jan; 88(2):1080-9.
    View in: PubMed
    Score: 0.183
  6. Dionne KR, Tyler KL. Slice culture modeling of central nervous system (CNS) viral infection. Methods Mol Biol. 2013; 1078:97-117.
    View in: PubMed
    Score: 0.172
  7. Dionne KR, Galvin JM, Schittone SA, Clarke P, Tyler KL. Type I interferon signaling limits reoviral tropism within the brain and prevents lethal systemic infection. J Neurovirol. 2011 Aug; 17(4):314-26.
    View in: PubMed
    Score: 0.155
  8. Tyler KL, Leser JS, Phang TL, Clarke P. Gene expression in the brain during reovirus encephalitis. J Neurovirol. 2010 Feb; 16(1):56-71.
    View in: PubMed
    Score: 0.141
  9. Clarke P, Beckham JD, Leser JS, Hoyt CC, Tyler KL. Fas-mediated apoptotic signaling in the mouse brain following reovirus infection. J Virol. 2009 Jun; 83(12):6161-70.
    View in: PubMed
    Score: 0.133
  10. Goody RJ, Beckham JD, Rubtsova K, Tyler KL. JAK-STAT signaling pathways are activated in the brain following reovirus infection. J Neurovirol. 2007 Aug; 13(4):373-83.
    View in: PubMed
    Score: 0.118
  11. Beckham JD, Tyler KL. Infectious disease - developments in the field of Creutzfeldt-Jakob disease. Rev Neurol Dis. 2007; 4(3):168-72.
    View in: PubMed
    Score: 0.114
  12. Richardson-Burns SM, Tyler KL. Regional differences in viral growth and central nervous system injury correlate with apoptosis. J Virol. 2004 May; 78(10):5466-75.
    View in: PubMed
    Score: 0.094
  13. Richardson-Burns SM, Kleinschmidt-DeMasters BK, DeBiasi RL, Tyler KL. Progressive multifocal leukoencephalopathy and apoptosis of infected oligodendrocytes in the central nervous system of patients with and without AIDS. Arch Neurol. 2002 Dec; 59(12):1930-6.
    View in: PubMed
    Score: 0.086
  14. Stonedahl S, Leser JS, Clarke P, Tyler KL. Depletion of Microglia in an Ex Vivo Brain Slice Culture Model of West Nile Virus Infection Leads to Increased Viral Titers and Cell Death. Microbiol Spectr. 2022 04 27; 10(2):e0068522.
    View in: PubMed
    Score: 0.082
  15. Dionne KR, Tyler KL, Clarke P. Slice Culture Modeling of CNS Viral Infection. Methods Mol Biol. 2021; 2311:109-130.
    View in: PubMed
    Score: 0.075
  16. Tyler KL, Malessa R. The Goltz-Ferrier debates and the triumph of cerebral localizationalist theory. Neurology. 2000 Oct 10; 55(7):1015-24.
    View in: PubMed
    Score: 0.074
  17. Clarke P, Zhuang Y, Berens HM, Leser JS, Tyler KL. Interferon Beta Contributes to Astrocyte Activation in the Brain following Reovirus Infection. J Virol. 2019 05 15; 93(10).
    View in: PubMed
    Score: 0.067
  18. Pelosi E, Rozenberg F, Coen DM, Tyler KL. A herpes simplex virus DNA polymerase mutation that specifically attenuates neurovirulence in mice. Virology. 1998 Dec 20; 252(2):364-72.
    View in: PubMed
    Score: 0.065
  19. Tyler KL. Acute Viral Encephalitis. N Engl J Med. 2018 Aug 09; 379(6):557-566.
    View in: PubMed
    Score: 0.063
  20. Oberhaus SM, Smith RL, Clayton GH, Dermody TS, Tyler KL. Reovirus infection and tissue injury in the mouse central nervous system are associated with apoptosis. J Virol. 1997 Mar; 71(3):2100-6.
    View in: PubMed
    Score: 0.057
  21. Tyler KL, Sandberg E, Baum KF. Medical medullary syndrome and meningovascular syphilis: a case report in an HIV-infected man and a review of the literature. Neurology. 1994 Dec; 44(12):2231-5.
    View in: PubMed
    Score: 0.049
  22. Berens HM, Tyler KL. The proapoptotic Bcl-2 protein Bax plays an important role in the pathogenesis of reovirus encephalitis. J Virol. 2011 Apr; 85(8):3858-71.
    View in: PubMed
    Score: 0.038
  23. Beckham JD, Tuttle K, Tyler KL. Reovirus activates transforming growth factor beta and bone morphogenetic protein signaling pathways in the central nervous system that contribute to neuronal survival following infection. J Virol. 2009 May; 83(10):5035-45.
    View in: PubMed
    Score: 0.033
  24. Davis LE, Beckham JD, Tyler KL. North American encephalitic arboviruses. Neurol Clin. 2008 Aug; 26(3):727-57, ix.
    View in: PubMed
    Score: 0.032
  25. Kaye KM, Spriggs DR, Bassel-Duby R, Fields BN, Tyler KL. Genetic basis for altered pathogenesis of an immune-selected antigenic variant of reovirus type 3 (Dearing). J Virol. 1986 Jul; 59(1):90-7.
    View in: PubMed
    Score: 0.027
  26. Kleinschmidt-DeMasters BK, Tyler KL. Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis. N Engl J Med. 2005 Jul 28; 353(4):369-74.
    View in: PubMed
    Score: 0.025
  27. Clarke P, Debiasi RL, Goody R, Hoyt CC, Richardson-Burns S, Tyler KL. Mechanisms of reovirus-induced cell death and tissue injury: role of apoptosis and virus-induced perturbation of host-cell signaling and transcription factor activation. Viral Immunol. 2005; 18(1):89-115.
    View in: PubMed
    Score: 0.025
  28. Tyler KL. Human herpesvirus 6 and multiple sclerosis: the continuing conundrum. J Infect Dis. 2003 May 01; 187(9):1360-4.
    View in: PubMed
    Score: 0.022
  29. Richardson-Burns SM, Kominsky DJ, Tyler KL. Reovirus-induced neuronal apoptosis is mediated by caspase 3 and is associated with the activation of death receptors. J Neurovirol. 2002 Oct; 8(5):365-80.
    View in: PubMed
    Score: 0.021
  30. Bonney S, Seitz S, Ryan CA, Jones KL, Clarke P, Tyler KL, Siegenthaler JA. Gamma Interferon Alters Junctional Integrity via Rho Kinase, Resulting in Blood-Brain Barrier Leakage in Experimental Viral Encephalitis. mBio. 2019 08 06; 10(4).
    View in: PubMed
    Score: 0.017
  31. Tyler KL. Prions and prion diseases of the central nervous system. Curr Clin Top Infect Dis. 1999; 19:226-51.
    View in: PubMed
    Score: 0.016
  32. Oberhaus SM, Dermody TS, Tyler KL. Apoptosis and the cytopathic effects of reovirus. Curr Top Microbiol Immunol. 1998; 233(Pt 2):23-49.
    View in: PubMed
    Score: 0.015
  33. Messacar K, Fischer M, Dominguez SR, Tyler KL, Abzug MJ. Encephalitis in US Children. Infect Dis Clin North Am. 2018 03; 32(1):145-162.
    View in: PubMed
    Score: 0.015
  34. Cleary MA, Walter JH, Wraith JE, White F, Tyler K, Jenkins JP. Magnetic resonance imaging in phenylketonuria: reversal of cerebral white matter change. J Pediatr. 1995 Aug; 127(2):251-5.
    View in: PubMed
    Score: 0.013
  35. Paskavitz JF, Anderson CA, Filley CM, Kleinschmidt-DeMasters BK, Tyler KL. Acute arcuate fiber demyelinating encephalopathy following Epstein-Barr virus infection. Ann Neurol. 1995 Jul; 38(1):127-31.
    View in: PubMed
    Score: 0.013
  36. Tyler KL, Virgin HW, Bassel-Duby R, Fields BN. Antibody inhibits defined stages in the pathogenesis of reovirus serotype 3 infection of the central nervous system. J Exp Med. 1989 Sep 01; 170(3):887-900.
    View in: PubMed
    Score: 0.009
  37. Virgin HW, Bassel-Duby R, Fields BN, Tyler KL. Antibody protects against lethal infection with the neurally spreading reovirus type 3 (Dearing). J Virol. 1988 Dec; 62(12):4594-604.
    View in: PubMed
    Score: 0.008
  38. Zimmermann AK, Loucks FA, Schroeder EK, Bouchard RJ, Tyler KL, Linseman DA. Glutathione binding to the Bcl-2 homology-3 domain groove: a molecular basis for Bcl-2 antioxidant function at mitochondria. J Biol Chem. 2007 Oct 05; 282(40):29296-304.
    View in: PubMed
    Score: 0.007
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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