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Connection

Trevor Williams to Transcription Factor AP-2

This is a "connection" page, showing publications Trevor Williams has written about Transcription Factor AP-2.

 
Connection Strength
  
 
 
6.357
  
  1. Van Otterloo E, Li H, Jones KL, Williams T. AP-2a and AP-2? cooperatively orchestrate homeobox gene expression during branchial arch patterning. Development. 2018 01 25; 145(2).
    View in: PubMed
    Score: 0.576
  2. Green RM, Feng W, Phang T, Fish JL, Li H, Spritz RA, Marcucio RS, Hooper J, Jamniczky H, Hallgr?msson B, Williams T. Tfap2a-dependent changes in mouse facial morphology result in clefting that can be ameliorated by a reduction in Fgf8 gene dosage. Dis Model Mech. 2015 Jan; 8(1):31-43.
    View in: PubMed
    Score: 0.461
  3. Li H, Sheridan R, Williams T. Analysis of TFAP2A mutations in Branchio-Oculo-Facial Syndrome indicates functional complexity within the AP-2a DNA-binding domain. Hum Mol Genet. 2013 Aug 15; 22(16):3195-206.
    View in: PubMed
    Score: 0.413
  4. Feng W, Simoes-de-Souza F, Finger TE, Restrepo D, Williams T. Disorganized olfactory bulb lamination in mice deficient for transcription factor AP-2epsilon. Mol Cell Neurosci. 2009 Nov; 42(3):161-71.
    View in: PubMed
    Score: 0.318
  5. Feng W, Huang J, Zhang J, Williams T. Identification and analysis of a conserved Tcfap2a intronic enhancer element required for expression in facial and limb bud mesenchyme. Mol Cell Biol. 2008 Jan; 28(1):315-25.
    View in: PubMed
    Score: 0.284
  6. Winger Q, Huang J, Auman HJ, Lewandoski M, Williams T. Analysis of transcription factor AP-2 expression and function during mouse preimplantation development. Biol Reprod. 2006 Sep; 75(3):324-33.
    View in: PubMed
    Score: 0.255
  7. Donner AL, Williams T. Frontal nasal prominence expression driven by Tcfap2a relies on a conserved binding site for STAT proteins. Dev Dyn. 2006 May; 235(5):1358-70.
    View in: PubMed
    Score: 0.255
  8. Van Otterloo E, Milanda I, Pike H, Thompson JA, Li H, Jones KL, Williams T. AP-2a and AP-2? cooperatively function in the craniofacial surface ectoderm to regulate chromatin and gene expression dynamics during facial development. Elife. 2022 03 25; 11.
    View in: PubMed
    Score: 0.192
  9. Taiyab A, Akula M, Dham J, Deschamps P, Sheardown H, Williams T, Borr?s T, West-Mays JA. Deletion of transcription factor AP-2? from the developing murine trabecular meshwork region leads to progressive glaucomatous changes. J Neurosci Res. 2022 02; 100(2):638-652.
    View in: PubMed
    Score: 0.188
  10. Walker H, Taiyab A, Deschamps P, Williams T, West-Mays JA. Conditional Deletion of AP-2? in the Periocular Mesenchyme of Mice Alters Corneal Epithelial Cell Fate and Stratification. Int J Mol Sci. 2021 Aug 13; 22(16).
    View in: PubMed
    Score: 0.184
  11. Taiyab A, Saraco A, Akula M, Deschamps P, Ball AK, Williams T, West-Mays JA. Progressive Loss of Retinal Ganglion Cells in Activating Protein-2? Neural Crest Cell Knockout Mice. Curr Eye Res. 2021 10; 46(10):1509-1515.
    View in: PubMed
    Score: 0.179
  12. Woodruff ED, Gutierrez GC, Van Otterloo E, Williams T, Cohn MJ. Anomalous incisor morphology indicates tissue-specific roles for Tfap2a and Tfap2b in tooth development. Dev Biol. 2021 04; 472:67-74.
    View in: PubMed
    Score: 0.177
  13. Gu VW, Cho E, Thompson DT, Cassady VC, Borcherding N, Koch KE, Wu VT, Lorenzen AW, van der Heide DM, White JR, Kulak MV, Williams T, Zhang W, Weigel RJ. AP-2? Is Required for Maintenance of Multipotent Mammary Stem Cells. Stem Cell Reports. 2021 01 12; 16(1):106-119.
    View in: PubMed
    Score: 0.176
  14. Akula M, Taiyab A, Deschamps P, Yee S, Ball AK, Williams T, West-Mays JA. AP-2? is required for formation of the murine trabecular meshwork and Schlemm's canal. Exp Eye Res. 2020 06; 195:108042.
    View in: PubMed
    Score: 0.168
  15. Kousa YA, Zhu H, Fakhouri WD, Lei Y, Kinoshita A, Roushangar RR, Patel NK, Agopian AJ, Yang W, Leslie EJ, Busch TD, Mansour TA, Li X, Smith AL, Li EB, Sharma DB, Williams TJ, Chai Y, Amendt BA, Liao EC, Mitchell LE, Bassuk AG, Gregory S, Ashley-Koch A, Shaw GM, Finnell RH, Schutte BC. The TFAP2A-IRF6-GRHL3 genetic pathway is conserved in neurulation. Hum Mol Genet. 2019 05 15; 28(10):1726-1737.
    View in: PubMed
    Score: 0.158
  16. Hicks EA, Zaveri M, Deschamps PA, Noseworthy MD, Ball A, Williams T, West-Mays JA. Conditional Deletion of AP-2a and AP-2? in the Developing Murine Retina Leads to Altered Amacrine Cell Mosaics and Disrupted Visual Function. Invest Ophthalmol Vis Sci. 2018 05 01; 59(6):2229-2239.
    View in: PubMed
    Score: 0.147
  17. Seberg HE, Van Otterloo E, Loftus SK, Liu H, Bonde G, Sompallae R, Gildea DE, Santana JF, Manak JR, Pavan WJ, Williams T, Cornell RA. TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF. PLoS Genet. 2017 03; 13(3):e1006636.
    View in: PubMed
    Score: 0.135
  18. Martino VB, Sabljic T, Deschamps P, Green RM, Akula M, Peacock E, Ball A, Williams T, West-Mays JA. Conditional deletion of AP-2? in mouse cranial neural crest results in anterior segment dysgenesis and early-onset glaucoma. Dis Model Mech. 2016 08 01; 9(8):849-61.
    View in: PubMed
    Score: 0.129
  19. Chen L, Martino V, Dombkowski A, Williams T, West-Mays J, Gage PJ. AP-2? Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development. Invest Ophthalmol Vis Sci. 2016 Mar; 57(3):1072-81.
    View in: PubMed
    Score: 0.126
  20. Kerr CL, Zaveri MA, Robinson ML, Williams T, West-Mays JA. AP-2a is required after lens vesicle formation to maintain lens integrity. Dev Dyn. 2014 Oct; 243(10):1298-309.
    View in: PubMed
    Score: 0.111
  21. Wang J, Bai Y, Li H, Greene SB, Klysik E, Yu W, Schwartz RJ, Williams TJ, Martin JF. MicroRNA-17-92, a direct Ap-2a transcriptional target, modulates T-box factor activity in orofacial clefting. PLoS Genet. 2013; 9(9):e1003785.
    View in: PubMed
    Score: 0.106
  22. Bassett EA, Korol A, Deschamps PA, Buettner R, Wallace VA, Williams T, West-Mays JA. Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Dev Dyn. 2012 Apr; 241(4):814-29.
    View in: PubMed
    Score: 0.096
  23. Schmidt M, Huber L, Majdazari A, Sch?tz G, Williams T, Rohrer H. The transcription factors AP-2? and AP-2a are required for survival of sympathetic progenitors and differentiated sympathetic neurons. Dev Biol. 2011 Jul 01; 355(1):89-100.
    View in: PubMed
    Score: 0.090
  24. Bassett EA, Williams T, Zacharias AL, Gage PJ, Fuhrmann S, West-Mays JA. AP-2alpha knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis. Hum Mol Genet. 2010 May 01; 19(9):1791-804.
    View in: PubMed
    Score: 0.083
  25. Wang X, Pasolli HA, Williams T, Fuchs E. AP-2 factors act in concert with Notch to orchestrate terminal differentiation in skin epidermis. J Cell Biol. 2008 Oct 06; 183(1):37-48.
    View in: PubMed
    Score: 0.075
  26. Pontoriero GF, Deschamps P, Ashery-Padan R, Wong R, Yang Y, Zavadil J, Cvekl A, Sullivan S, Williams T, West-Mays JA. Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype. Dev Dyn. 2008 Mar; 237(3):602-17.
    View in: PubMed
    Score: 0.072
  27. Guttormsen J, Koster MI, Stevens JR, Roop DR, Williams T, Winger QA. Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice. Dev Biol. 2008 May 01; 317(1):187-95.
    View in: PubMed
    Score: 0.072
  28. Bassett EA, Pontoriero GF, Feng W, Marquardt T, Fini ME, Williams T, West-Mays JA. Conditional deletion of activating protein 2alpha (AP-2alpha) in the developing retina demonstrates non-cell-autonomous roles for AP-2alpha in optic cup development. Mol Cell Biol. 2007 Nov; 27(21):7497-510.
    View in: PubMed
    Score: 0.070
  29. Makhani LF, Williams T, West-Mays JA. Genetic analysis indicates that transcription factors AP-2alpha and Pax6 cooperate in the normal patterning and morphogenesis of the lens. Mol Vis. 2007 Jul 19; 13:1215-25.
    View in: PubMed
    Score: 0.069
  30. Wang X, Bolotin D, Chu DH, Polak L, Williams T, Fuchs E. AP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermis. J Cell Biol. 2006 Jan 30; 172(3):409-21.
    View in: PubMed
    Score: 0.063
  31. Koster MI, Kim S, Huang J, Williams T, Roop DR. TAp63alpha induces AP-2gamma as an early event in epidermal morphogenesis. Dev Biol. 2006 Jan 01; 289(1):253-61.
    View in: PubMed
    Score: 0.062
  32. Brewer S, Williams T. Loss of AP-2alpha impacts multiple aspects of ventral body wall development and closure. Dev Biol. 2004 Mar 15; 267(2):399-417.
    View in: PubMed
    Score: 0.055
  33. Brewer S, Feng W, Huang J, Sullivan S, Williams T. Wnt1-Cre-mediated deletion of AP-2alpha causes multiple neural crest-related defects. Dev Biol. 2004 Mar 01; 267(1):135-52.
    View in: PubMed
    Score: 0.055
  34. Nguyen TT, Mitchell JM, Kiel MD, Kenny CP, Li H, Jones KL, Cornell RA, Williams TJ, Nichols JT, Van Otterloo E. TFAP2 paralogs regulate midfacial development in part through a conserved ALX genetic pathway. Development. 2024 Jan 01; 151(1).
    View in: PubMed
    Score: 0.054
  35. Feng W, Williams T. Cloning and characterization of the mouse AP-2 epsilon gene: a novel family member expressed in the developing olfactory bulb. Mol Cell Neurosci. 2003 Oct; 24(2):460-75.
    View in: PubMed
    Score: 0.053
  36. Zhang J, Brewer S, Huang J, Williams T. Overexpression of transcription factor AP-2alpha suppresses mammary gland growth and morphogenesis. Dev Biol. 2003 Apr 01; 256(1):127-45.
    View in: PubMed
    Score: 0.052
  37. Auman HJ, Nottoli T, Lakiza O, Winger Q, Donaldson S, Williams T. Transcription factor AP-2gamma is essential in the extra-embryonic lineages for early postimplantation development. Development. 2002 Jun; 129(11):2733-47.
    View in: PubMed
    Score: 0.049
  38. Mohibullah N, Donner A, Ippolito JA, Williams T. SELEX and missing phosphate contact analyses reveal flexibility within the AP-2[alpha] protein: DNA binding complex. Nucleic Acids Res. 1999 Jul 01; 27(13):2760-9.
    View in: PubMed
    Score: 0.040
  39. Fr?b F, Sock E, Tamm ER, Saur AL, Hillg?rtner S, Williams TJ, Fujii T, Fukunaga R, Wegner M. Ep400 deficiency in Schwann cells causes persistent expression of early developmental regulators and peripheral neuropathy. Nat Commun. 2019 05 29; 10(1):2361.
    View in: PubMed
    Score: 0.039
  40. West-Mays JA, Zhang J, Nottoli T, Hagopian-Donaldson S, Libby D, Strissel KJ, Williams T. AP-2alpha transcription factor is required for early morphogenesis of the lens vesicle. Dev Biol. 1999 Feb 01; 206(1):46-62.
    View in: PubMed
    Score: 0.039
  41. Turner BC, Zhang J, Gumbs AA, Maher MG, Kaplan L, Carter D, Glazer PM, Hurst HC, Haffty BG, Williams T. Expression of AP-2 transcription factors in human breast cancer correlates with the regulation of multiple growth factor signalling pathways. Cancer Res. 1998 Dec 01; 58(23):5466-72.
    View in: PubMed
    Score: 0.038
  42. Nottoli T, Hagopian-Donaldson S, Zhang J, Perkins A, Williams T. AP-2-null cells disrupt morphogenesis of the eye, face, and limbs in chimeric mice. Proc Natl Acad Sci U S A. 1998 Nov 10; 95(23):13714-9.
    View in: PubMed
    Score: 0.038
  43. Creaser PC, D'Argenio DA, Williams T. Comparative and functional analysis of the AP2 promoter indicates that conserved octamer and initiator elements are critical for activity. Nucleic Acids Res. 1996 Jul 01; 24(13):2597-605.
    View in: PubMed
    Score: 0.032
  44. Zhang J, Hagopian-Donaldson S, Serbedzija G, Elsemore J, Plehn-Dujowich D, McMahon AP, Flavell RA, Williams T. Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2. Nature. 1996 May 16; 381(6579):238-41.
    View in: PubMed
    Score: 0.032
  45. Warren G, Gordon M, Siracusa LD, Buchberg AM, Williams T. Physical and genetic localization of the gene encoding the AP-2 transcription factor to mouse chromosome 13. Genomics. 1996 Jan 15; 31(2):234-7.
    View in: PubMed
    Score: 0.031
  46. Williams T, Tjian R. Analysis of the DNA-binding and activation properties of the human transcription factor AP-2. Genes Dev. 1991 Apr; 5(4):670-82.
    View in: PubMed
    Score: 0.022
  47. Williams T, Tjian R. Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteins. Science. 1991 Mar 01; 251(4997):1067-71.
    View in: PubMed
    Score: 0.022
  48. Williams T, Admon A, L?scher B, Tjian R. Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements. Genes Dev. 1988 Dec; 2(12A):1557-69.
    View in: PubMed
    Score: 0.019
  49. Sumigama S, Ito T, Kajiyama H, Shibata K, Tamakoshi K, Kikkawa F, Williams T, Tainsky MA, Nomura S, Mizutani S. Suppression of invasion and peritoneal carcinomatosis of ovarian cancer cells by overexpression of AP-2alpha. Oncogene. 2004 Jul 15; 23(32):5496-504.
    View in: PubMed
    Score: 0.014
  50. Ahituv N, Erven A, Fuchs H, Guy K, Ashery-Padan R, Williams T, de Angelis MH, Avraham KB, Steel KP. An ENU-induced mutation in AP-2alpha leads to middle ear and ocular defects in Doarad mice. Mamm Genome. 2004 Jun; 15(6):424-32.
    View in: PubMed
    Score: 0.014
  51. Douglas DB, Akiyama Y, Carraway H, Belinsky SA, Esteller M, Gabrielson E, Weitzman S, Williams T, Herman JG, Baylin SB. Hypermethylation of a small CpGuanine-rich region correlates with loss of activator protein-2alpha expression during progression of breast cancer. Cancer Res. 2004 Mar 01; 64(5):1611-20.
    View in: PubMed
    Score: 0.014
  52. Sivak JM, West-Mays JA, Yee A, Williams T, Fini ME. Transcription Factors Pax6 and AP-2alpha Interact To Coordinate Corneal Epithelial Repair by Controlling Expression of Matrix Metalloproteinase Gelatinase B. Mol Cell Biol. 2004 Jan; 24(1):245-57.
    View in: PubMed
    Score: 0.014
  53. West-Mays JA, Sivak JM, Papagiotas SS, Kim J, Nottoli T, Williams T, Fini ME. Positive influence of AP-2alpha transcription factor on cadherin gene expression and differentiation of the ocular surface. Differentiation. 2003 Apr; 71(3):206-16.
    View in: PubMed
    Score: 0.013
  54. Kennedy B, Enns R, Nelson D, Williams T, Bao X, Ziegler MG. Reduction of adrenal and kidney epinephrine and phenylethanolamine N-methyltransferase in AP-2 knockout mouse fetuses. Ann N Y Acad Sci. 2002 Oct; 971:92-4.
    View in: PubMed
    Score: 0.012
  55. Brewer S, Jiang X, Donaldson S, Williams T, Sucov HM. Requirement for AP-2alpha in cardiac outflow tract morphogenesis. Mech Dev. 2002 Jan; 110(1-2):139-49.
    View in: PubMed
    Score: 0.012
  56. Mazina OM, Phillips MA, Williams T, Vines CA, Cherr GN, Rice RH. Redistribution of transcription factor AP-2alpha in differentiating cultured human epidermal cells. J Invest Dermatol. 2001 Oct; 117(4):864-70.
    View in: PubMed
    Score: 0.012
  57. Beger M, Butz K, Denk C, Williams T, Hurst HC, Hoppe-Seyler F. Expression pattern of AP-2 transcription factors in cervical cancer cells and analysis of their influence on human papillomavirus oncogene transcription. J Mol Med (Berl). 2001 Jun; 79(5-6):314-20.
    View in: PubMed
    Score: 0.011
  58. Pena P, Reutens AT, Albanese C, D'Amico M, Watanabe G, Donner A, Shu IW, Williams T, Pestell RG. Activator protein-2 mediates transcriptional activation of the CYP11A1 gene by interaction with Sp1 rather than binding to DNA. Mol Endocrinol. 1999 Aug; 13(8):1402-16.
    View in: PubMed
    Score: 0.010
  59. Shen H, Wilke T, Ashique AM, Narvey M, Zerucha T, Savino E, Williams T, Richman JM. Chicken transcription factor AP-2: cloning, expression and its role in outgrowth of facial prominences and limb buds. Dev Biol. 1997 Aug 15; 188(2):248-66.
    View in: PubMed
    Score: 0.009
  60. Johnson W, Albanese C, Handwerger S, Williams T, Pestell RG, Jameson JL. Regulation of the human chorionic gonadotropin alpha- and beta-subunit promoters by AP-2. J Biol Chem. 1997 Jun 13; 272(24):15405-12.
    View in: PubMed
    Score: 0.009
  61. Bosher JM, Totty NF, Hsuan JJ, Williams T, Hurst HC. A family of AP-2 proteins regulates c-erbB-2 expression in mammary carcinoma. Oncogene. 1996 Oct 17; 13(8):1701-7.
    View in: PubMed
    Score: 0.008
  62. Williamson JA, Bosher JM, Skinner A, Sheer D, Williams T, Hurst HC. Chromosomal mapping of the human and mouse homologues of two new members of the AP-2 family of transcription factors. Genomics. 1996 Jul 01; 35(1):262-4.
    View in: PubMed
    Score: 0.008
  63. Somasundaram K, Jayaraman G, Williams T, Moran E, Frisch S, Thimmapaya B. Repression of a matrix metalloprotease gene by E1A correlates with its ability to bind to cell type-specific transcription factor AP-2. Proc Natl Acad Sci U S A. 1996 Apr 02; 93(7):3088-93.
    View in: PubMed
    Score: 0.008
  64. Bosher JM, Williams T, Hurst HC. The developmentally regulated transcription factor AP-2 is involved in c-erbB-2 overexpression in human mammary carcinoma. Proc Natl Acad Sci U S A. 1995 Jan 31; 92(3):744-7.
    View in: PubMed
    Score: 0.007
  65. Mellentin-Michelotti J, John S, Pennie WD, Williams T, Hager GL. The 5' enhancer of the mouse mammary tumor virus long terminal repeat contains a functional AP-2 element. J Biol Chem. 1994 Dec 16; 269(50):31983-90.
    View in: PubMed
    Score: 0.007
  66. Lafyatis R, Denhez F, Williams T, Sporn M, Roberts A. Sequence specific protein binding to and activation of the TGF-beta 3 promoter through a repeated TCCC motif. Nucleic Acids Res. 1991 Dec 11; 19(23):6419-25.
    View in: PubMed
    Score: 0.006
  67. L?scher B, Mitchell PJ, Williams T, Tjian R. Regulation of transcription factor AP-2 by the morphogen retinoic acid and by second messengers. Genes Dev. 1989 Oct; 3(10):1507-17.
    View in: PubMed
    Score: 0.005
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