 Galectins
"Galectins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of animal lectins that bind specifically to beta-galactoside in a calcium-independent manner. Members of this class are distiguished from other lectins by the presence of a conserved carbohydrate recognition domain. The majority of proteins in this class bind to sugar molecules in a sulfhydryl-dependent manner and are often referred to as S-type lectins, however this property is not required for membership in this class.
| Descriptor ID |
D037161
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| MeSH Number(s) |
D12.776.503.307
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| Concept/Terms |
Galectins- Galectins
- beta-Galactoside Binding Lectin
- Binding Lectin, beta-Galactoside
- Lectin, beta-Galactoside Binding
- beta Galactoside Binding Lectin
- D-Galactoside-Binding Lectin
- D Galactoside Binding Lectin
- Lectin, D-Galactoside-Binding
- S-Type Lectins
- S Type Lectins
- Galaptins
- Galectin
- Lectins, S-Type
- Lectins, S Type
- S-Type Lectin
- Lectin, S-Type
- S Type Lectin
- beta-D-Galactosyl-Specific Lectin
- Lectin, beta-D-Galactosyl-Specific
- beta D Galactosyl Specific Lectin
- Galactose-Binding Lectin
- Galactose Binding Lectin
- Lectin, Galactose-Binding
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Below are MeSH descriptors whose meaning is more general than "Galectins".
Below are MeSH descriptors whose meaning is more specific than "Galectins".
This graph shows the total number of publications written about "Galectins" by people in this website by year, and whether "Galectins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 1 | 2 | | 2012 | 2 | 0 | 2 | | 2013 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2018 | 1 | 1 | 2 | | 2019 | 1 | 0 | 1 | | 2022 | 2 | 1 | 3 |
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Below are the most recent publications written about "Galectins" by people in Profiles.
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Cervantes-Alvarez E, Limon-de la Rosa N, Vilatoba M, P?rez-Monter C, Hurtado-Gomez S, Martinez-Cabrera C, Argemi J, Alatorre-Arenas E, Yarza-Regalado S, Tejeda-Dominguez F, Lizardo-Thiebaud MJ, Mendez-Guerrero O, Gamboa-Dominguez A, Aguilar-Salinas CA, Huang CA, Kershenobich D, Bataller R, Torre A, Navarro-Alvarez N. Galectin-3 is overexpressed in advanced cirrhosis and predicts post-liver transplant infectious complications. Liver Int. 2022 10; 42(10):2260-2273.
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Lee M, Hamilton JAG, Talekar GR, Ross AJ, Michael L, Rupji M, Dwivedi B, Raikar SS, Boss J, Scharer CD, Graham DK, DeRyckere D, Porter CC, Henry CJ. Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia. Nat Commun. 2022 03 03; 13(1):1157.
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Cervantes-Alvarez E, la Rosa NL, la Mora MS, Valdez-Sandoval P, Palacios-Jimenez M, Rodriguez-Alvarez F, Vera-Maldonado BI, Aguirre-Aguilar E, Escobar-Valderrama JM, Alanis-Mendizabal J, M?ndez-Guerrero O, Tejeda-Dominguez F, Torres-Ru?z J, G?mez-Mart?n D, Colborn KL, Kershenobich D, Huang CA, Navarro-Alvarez N. Galectin-3 as a potential prognostic biomarker of severe COVID-19 in SARS-CoV-2 infected patients. Sci Rep. 2022 02 03; 12(1):1856.
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Ueki S, Miyabe Y, Yamamoto Y, Fukuchi M, Hirokawa M, Spencer LA, Weller PF. Charcot-Leyden Crystals in Eosinophilic Inflammation: Active Cytolysis Leads to Crystal Formation. Curr Allergy Asthma Rep. 2019 06 15; 19(8):35.
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Ueki S, Tokunaga T, Melo RCN, Saito H, Honda K, Fukuchi M, Konno Y, Takeda M, Yamamoto Y, Hirokawa M, Fujieda S, Spencer LA, Weller PF. Charcot-Leyden crystal formation is closely associated with eosinophil extracellular trap cell death. Blood. 2018 11 15; 132(20):2183-2187.
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Smith LK, Boukhaled GM, Condotta SA, Mazouz S, Guthmiller JJ, Vijay R, Butler NS, Bruneau J, Shoukry NH, Krawczyk CM, Richer MJ. Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity. Immunity. 2018 02 20; 48(2):299-312.e5.
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Elmwall J, Kwiecinski J, Na M, Ali AA, Osla V, Shaw LN, Wang W, S?vman K, Josefsson E, Bylund J, Jin T, Welin A, Karlsson A. Galectin-3 Is a Target for Proteases Involved in the Virulence of Staphylococcus aureus. Infect Immun. 2017 07; 85(7).
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Rosen HR, Golden-Mason L, Daly AK, Yang I, Day CP. Variants in the LGALS9 Gene Are Associated With Development of Liver Disease in Heavy Consumers of Alcohol. Clin Gastroenterol Hepatol. 2016 May; 14(5):762-8.e1.
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Rosen HR, Biggins SW, Niki T, Gralla J, Hillman H, Hirashima M, Schilsky M, Lee WM. Association Between Plasma Level of Galectin-9 and Survival of Patients With Drug-Induced Acute Liver Failure. Clin Gastroenterol Hepatol. 2016 Apr; 14(4):606-612.e3.
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Harwood NM, Golden-Mason L, Cheng L, Rosen HR, Mengshol JA. HCV-infected cells and differentiation increase monocyte immunoregulatory galectin-9 production. J Leukoc Biol. 2016 Mar; 99(3):495-503.
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