 Iduronidase
"Iduronidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that hydrolyzes iduronosidic linkages in desulfated dermatan. Deficiency of this enzyme produces Hurler's syndrome. EC 3.2.1.76.
| Descriptor ID |
D007068
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| MeSH Number(s) |
D08.811.277.450.560
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| Concept/Terms |
Iduronidase- Iduronidase
- alpha-L-Idosiduronase
- alpha L Idosiduronase
- alpha-L-Iduronidase
- alpha L Iduronidase
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Below are MeSH descriptors whose meaning is more general than "Iduronidase".
Below are MeSH descriptors whose meaning is more specific than "Iduronidase".
This graph shows the total number of publications written about "Iduronidase" by people in this website by year, and whether "Iduronidase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Iduronidase" by people in Profiles.
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Chen AH, Harmatz P, Nestrasil I, Eisengart JB, King KE, Rudser K, Kaizer AM, Svatkova A, Wakumoto A, Le SQ, Madden J, Young S, Zhang H, Polgreen LE, Dickson PI. Intrathecal enzyme replacement for cognitive decline in mucopolysaccharidosis type I, a randomized, open-label, controlled pilot study. Mol Genet Metab. 2020 02; 129(2):80-90.
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Thomas JA, Jacobs S, Kierstein J, Van Hove J. Outcome after three years of laronidase enzyme replacement therapy in a patient with Hurler syndrome. J Inherit Metab Dis. 2006 Dec; 29(6):762.
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