 Antidepressive Agents
"Antidepressive Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.
| Descriptor ID |
D000928
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| MeSH Number(s) |
D27.505.954.427.700.122
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| Concept/Terms |
Antidepressive Agents- Antidepressive Agents
- Agents, Antidepressive
- Antidepressant Drugs
- Drugs, Antidepressant
- Antidepressants
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Below are MeSH descriptors whose meaning is more general than "Antidepressive Agents".
Below are MeSH descriptors whose meaning is more specific than "Antidepressive Agents".
This graph shows the total number of publications written about "Antidepressive Agents" by people in this website by year, and whether "Antidepressive Agents" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 1 | 1 | 2 | | 1999 | 1 | 2 | 3 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2004 | 2 | 0 | 2 | | 2005 | 3 | 4 | 7 | | 2006 | 1 | 3 | 4 | | 2007 | 5 | 0 | 5 | | 2008 | 2 | 8 | 10 | | 2009 | 5 | 2 | 7 | | 2010 | 4 | 1 | 5 | | 2011 | 8 | 3 | 11 | | 2012 | 8 | 7 | 15 | | 2013 | 6 | 5 | 11 | | 2014 | 9 | 2 | 11 | | 2015 | 5 | 3 | 8 | | 2016 | 9 | 6 | 15 | | 2017 | 10 | 0 | 10 | | 2018 | 8 | 5 | 13 | | 2019 | 6 | 5 | 11 | | 2020 | 6 | 4 | 10 | | 2021 | 3 | 5 | 8 | | 2022 | 1 | 3 | 4 | | 2023 | 1 | 3 | 4 | | 2024 | 5 | 6 | 11 | | 2025 | 6 | 1 | 7 |
To return to the timeline, click here.
Below are the most recent publications written about "Antidepressive Agents" by people in Profiles.
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Gomez-Lumbreras A, Tawfik AG, Del Fiol G, Kawamoto K, Reese T, Trinkley K, Jones A, Mitchell J, Malone DC. Risk of gastrointestinal bleeding by specific SSRIs and SNRIs: A systematic review and meta-analysis. Br J Clin Pharmacol. 2026 Mar; 92(3):793-808.
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Whaites Heinonen E, Bandoli G, Robertson B, Yonemitsu C, Bode L, Riedy H, Bertrand K, Chambers C. Varied human milk oligosaccharides in human milk from mothers treated with antidepressants and anti-inflammatories. Pediatr Res. 2026 Jul; 100(2):846-855.
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Ali DA, Hale E, Ascencio A, Berkowitz SJ. Antidepressant pharmacotherapy in childhood PTSD with and without comorbid ADHD: a nationwide retrospective study. J Psychiatr Res. 2025 10; 190:199-204.
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Whaites Heinonen E, Johnson DL, Todd A, Chambers CD. Lower Adherence to Breastfeeding Recommendations in Mothers Treated With Antirheumatic and Antidepressant Medications. J Hum Lact. 2025 08; 41(3):412-422.
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Ozmen O, Rush E, Park BH, Jones M, Trafton J, Brenner L, Rupper RW, Ward M, Nebeker JR, Pizer SD. Combining Machine Learning and Comparative Effectiveness Methodology to Study Primary Care Pharmacotherapy Pathways for Veterans With Depression. Med Care. 2025 06 01; 63(6):422-429.
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Kamp M, Lo CWH, Kokkinidis G, Chauhan M, Gillett AC, McIntosh AM, Pain O, Lewis CM. Sociodemographic, clinical, and genetic factors associated with self-reported antidepressant response outcomes in the UK Biobank. Psychol Med. 2025 Mar 12; 55:e80.
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Whaites Heinonen E, Bertrand K, Chambers C. Macronutrients in Human Milk Exposed to Antidepressant and Anti-Inflammatory Medications. JAMA Netw Open. 2025 01 02; 8(1):e2453332.
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Fabiano N, Wong S, Gupta A, Tran J, Bhambra N, Min KK, Dragioti E, Barbui C, Fiedorowicz JG, Gosling CJ, Cortese S, Gandhi J, Saraf G, Shorr R, Vigod SN, Frey BN, Delorme R, Solmi M. Safety of psychotropic medications in pregnancy: an umbrella review. Mol Psychiatry. 2025 01; 30(1):327-335.
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Li D, Pain O, Fabbri C, Wong WLE, Lo CWH, Ripke S, Cattaneo A, Souery D, Dernovsek MZ, Henigsberg N, Hauser J, Lewis G, Mors O, Perroud N, Rietschel M, Uher R, Maier W, Baune BT, Biernacka JM, Bondolfi G, Domschke K, Kato M, Liu YL, Serretti A, Tsai SJ, Weinshilboum R, McIntosh AM, Lewis CM. Metabolic activity of CYP2C19 and CYP2D6 on antidepressant response from 13 clinical studies using genotype imputation: a meta-analysis. Transl Psychiatry. 2024 07 19; 14(1):296.
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Petimar J, Young JG, Yu H, Rifas-Shiman SL, Daley MF, Heerman WJ, Janicke DM, Jones WS, Lewis KH, Lin PD, Prentice C, Merriman JW, Toh S, Block JP. Medication-Induced Weight Change Across Common Antidepressant Treatments : A Target Trial Emulation Study. Ann Intern Med. 2024 08; 177(8):993-1003.
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