 Ophthalmoplegia, Chronic Progressive External
"Ophthalmoplegia, Chronic Progressive External" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitochondrial myopathy characterized by slowly progressive paralysis of the levator palpebrae, orbicularis oculi, and extraocular muscles. Ragged-red fibers and atrophy are found on muscle biopsy. Familial and sporadic forms may occur. Disease onset is usually in the first or second decade of life, and the illness slowly progresses until usually all ocular motility is lost. (From Adams et al., Principles of Neurology, 6th ed, p1422)
| Descriptor ID |
D017246
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| MeSH Number(s) |
C05.651.460.700 C10.292.562.750.250 C10.597.622.447.511 C10.668.491.500.700 C11.590.472.250 C18.452.660.560.700 C23.888.592.636.447.511
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| Concept/Terms |
Ophthalmoplegia, Chronic Progressive External- Ophthalmoplegia, Chronic Progressive External
- Graefe Disease
- Disease, Graefe
- Mitochondrial Ocular Myopathy
- Myopathy, Mitochondrial Ocular
- Ocular Myopathy, Mitochondrial
- Chronic Progressive External Ophthalmoplegia
- Graefe's Disease
- Ocular Myopathy of Von Graefe-Fuchs
- Ocular Myopathy of Von Graefe Fuchs
- Ophthalmoplegia, Progressive External
- External Ophthalmoplegia, Progressive
- Progressive External Ophthalmoplegia
- CPEO
- Ocular Muscular Dystrophy
- Dystrophy, Ocular Muscular
- Muscular Dystrophies, Ocular
- Muscular Dystrophy, Ocular
- Ocular Muscular Dystrophies
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Below are MeSH descriptors whose meaning is more general than "Ophthalmoplegia, Chronic Progressive External".
Below are MeSH descriptors whose meaning is more specific than "Ophthalmoplegia, Chronic Progressive External".
This graph shows the total number of publications written about "Ophthalmoplegia, Chronic Progressive External" by people in this website by year, and whether "Ophthalmoplegia, Chronic Progressive External" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ophthalmoplegia, Chronic Progressive External" by people in Profiles.
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Wong JC, Foster LA, Sadjadi R. A clue for familial mitochondrial disorder: Discovering a vintage painting. Neurology. 2018 02 06; 90(6):294-295.
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Van Hove JL, Cunningham V, Rice C, Ringel SP, Zhang Q, Chou PC, Truong CK, Wong LJ. Finding twinkle in the eyes of a 71-year-old lady: a case report and review of the genotypic and phenotypic spectrum of TWINKLE-related dominant disease. Am J Med Genet A. 2009 May; 149A(5):861-7.
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Colyer MH, Bower KS, Ward TP, Hidayat AA, Subramanian PS. Mitochondrial myopathy presenting with segmental corneal oedema and retrocorneal membrane. Br J Ophthalmol. 2007 May; 91(5):696-7.
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