Amifostine
"Amifostine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Descriptor ID |
D004999
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MeSH Number(s) |
D02.705.400.625.050 D02.705.539.345.050 D02.886.300.692.050
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Concept/Terms |
Amifostine- Amifostine
- Amifostine Trihydrate
- Trihydrate, Amifostine
- APAETP
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Below are MeSH descriptors whose meaning is more general than "Amifostine".
Below are MeSH descriptors whose meaning is more specific than "Amifostine".
This graph shows the total number of publications written about "Amifostine" by people in this website by year, and whether "Amifostine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 1 | 0 | 1 |
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Below are the most recent publications written about "Amifostine" by people in Profiles.
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Marina N, Chang KW, Malogolowkin M, London WB, Frazier AL, Womer RB, Rescorla F, Billmire DF, Davis MM, Perlman EJ, Giller R, Lauer SJ, Olson TA. Amifostine does not protect against the ototoxicity of high-dose cisplatin combined with etoposide and bleomycin in pediatric germ-cell tumors: a Children's Oncology Group study. Cancer. 2005 Aug 15; 104(4):841-7.
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Myerson R, Zobeiri I, Birnbaum E, Dietz D, Fleshman J, Kodner I, Picus J, Ratkin G. Early results from a phase I/II radiation dose-escalation study with concurrent amifostine and infusional 5-fluorouracil chemotherapy for preoperative treatment of unresectable or locally recurrent rectal carcinoma. Semin Oncol. 2002 Dec; 29(6 Suppl 19):29-33.
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