Leukostasis
"Leukostasis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Abnormal intravascular leukocyte aggregation and clumping often seen in leukemia patients. The brain and lungs are the two most commonly affected organs. This acute syndrome requires aggressive cytoreductive modalities including chemotherapy and/or leukophoresis. It is differentiated from LEUKEMIC INFILTRATION which is a neoplastic process where leukemic cells invade organs.
| Descriptor ID |
D018921
|
| MeSH Number(s) |
C15.378.553.560
|
| Concept/Terms |
Leukostasis- Leukostasis
- Leukostases
- Leukostasis Syndrome
- Leukostasis Syndromes
- Syndrome, Leukostasis
- Syndromes, Leukostasis
|
Below are MeSH descriptors whose meaning is more general than "Leukostasis".
Below are MeSH descriptors whose meaning is more specific than "Leukostasis".
This graph shows the total number of publications written about "Leukostasis" by people in this website by year, and whether "Leukostasis" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukostasis" by people in Profiles.
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Thakur A, Scheinman RI, Rao VR, Kompella UB. Pazopanib, a multitargeted tyrosine kinase inhibitor, reduces diabetic retinal vascular leukostasis and leakage. Microvasc Res. 2011 Nov; 82(3):346-50.
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Rao VR, Prescott E, Shelke NB, Trivedi R, Thomas P, Struble C, Gadek T, O'Neill CA, Kompella UB. Delivery of SAR 1118 to the retina via ophthalmic drops and its effectiveness in a rat streptozotocin (STZ) model of diabetic retinopathy (DR). Invest Ophthalmol Vis Sci. 2010 Oct; 51(10):5198-204.