 Azoxymethane
"Azoxymethane" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent carcinogen and neurotoxic compound. It is particularly effective in inducing colon carcinomas.
| Descriptor ID |
D001397
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| MeSH Number(s) |
D02.172.080
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Azoxymethane".
Below are MeSH descriptors whose meaning is more specific than "Azoxymethane".
This graph shows the total number of publications written about "Azoxymethane" by people in this website by year, and whether "Azoxymethane" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 | | 2010 | 1 | 1 | 2 | | 2013 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Azoxymethane" by people in Profiles.
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Flynn CL, Markey GE, Neudecker V, Farrelly C, Furuta GT, Eltzschig HK, Masterson JC, McNamee EN. The MicroRNA miR-223 Constrains Colitis-associated Tumorigenesis by Limiting Myeloid Cell Infiltration and Chemokine Expression. J Immunol. 2024 Dec 15; 213(12):1869-1883.
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Kumar R, Maurya AK, Parker KD, Kant R, Ibrahim H, Kabir MI, Kumar D, Weber AM, Agarwal R, Kuhn KA, Ryan EP, Raina K. Gender-based effect of absence of gut microbiota on the protective efficacy of Bifidobacterium longum-fermented rice bran diet against inflammation-associated colon tumorigenesis. Mol Carcinog. 2022 10; 61(10):941-957.
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Zhang Y, Diao N, Lee CK, Chu HW, Bai L, Li L. Neutrophils Deficient in Innate Suppressor IRAK-M Enhances Anti-tumor Immune Responses. Mol Ther. 2020 01 08; 28(1):89-99.
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Sharp SP, Malizia RA, Walrath T, D'Souza SS, Booth CJ, Kartchner BJ, Lee EC, Stain SC, O'Connor W. DNA damage response genes mark the early transition from colitis to neoplasia in colitis-associated colon cancer. Gene. 2018 Nov 30; 677:299-307.
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Han J, Jackson D, Holm J, Turner K, Ashcraft P, Wang X, Cook B, Arning E, Genta RM, Venuprasad K, Souza RF, Sweetman L, Theiss AL. Elevated d-2-hydroxyglutarate during colitis drives progression to colorectal cancer. Proc Natl Acad Sci U S A. 2018 01 30; 115(5):1057-1062.
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Charepalli V, Reddivari L, Radhakrishnan S, Vadde R, Agarwal R, Vanamala JK. Anthocyanin-containing purple-fleshed potatoes suppress colon tumorigenesis via elimination of colon cancer stem cells. J Nutr Biochem. 2015 Dec; 26(12):1641-9.
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Whetstone RD, Wittel UA, Michels NM, Gulizia JM, Gold B. Colon carcinogenesis in wild type and immune compromised mice after treatment with azoxymethane, and azoxymethane with dextran sodium sulfate. Mol Carcinog. 2016 07; 55(7):1187-95.
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Derry MM, Raina K, Agarwal R, Agarwal C. Characterization of azoxymethane-induced colon tumor metastasis to lung in a mouse model relevant to human sporadic colorectal cancer and evaluation of grape seed extract efficacy. Exp Toxicol Pathol. 2014 Aug; 66(5-6):235-42.
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Derry MM, Raina K, Balaiya V, Jain AK, Shrotriya S, Huber KM, Serkova NJ, Agarwal R, Agarwal C. Grape seed extract efficacy against azoxymethane-induced colon tumorigenesis in A/J mice: interlinking miRNA with cytokine signaling and inflammation. Cancer Prev Res (Phila). 2013 Jul; 6(7):625-33.
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Ravichandran K, Velmurugan B, Gu M, Singh RP, Agarwal R. Inhibitory effect of silibinin against azoxymethane-induced colon tumorigenesis in A/J mice. Clin Cancer Res. 2010 Sep 15; 16(18):4595-606.
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