Trimetrexate
"Trimetrexate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against PNEUMOCYSTIS PNEUMONIA in AIDS patients. Myelosuppression is its dose-limiting toxic effect.
| Descriptor ID |
D016597
|
| MeSH Number(s) |
D03.633.100.786.925
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Trimetrexate".
Below are MeSH descriptors whose meaning is more specific than "Trimetrexate".
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Below are the most recent publications written about "Trimetrexate" by people in Profiles.